M2: Neuropathologies
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Questions and Answers

This lobe is responsible for planning and executing volitional behavior.

  • Frontal (correct)
  • Temporal
  • Parietal
  • Occipital

This side of the temporal lobe appears to be important for the interpretation of complex nonverbal visual stimuli and for recognition and comprehension of nonverbal sounds, including receptive components of music.

  • Anterior temporal lobe
  • Right temporal lobe (correct)
  • Left temporal lobe
  • Association cortex

This lobe is important for perception, integration, and mediation of touch, body awareness, and visuospatial information.

  • Frontal
  • Temporal
  • Parietal (correct)
  • Occipital

Damage in the association cortex in either of these lobes typically disturbs position sense and causes various visuospatial impairments.

<p>Parietal (C)</p> Signup and view all the answers

Damage in the association cortex adjacent to the visual cortex in either hemisphere typically causes visual agnosia and distorted visual perceptions

<p>Occipital (D)</p> Signup and view all the answers

Damage to the primary motor cortex causes weakness or paralysis of muscle groups on what side of the body?

<p>Contralateral (B)</p> Signup and view all the answers

This portion of the temporal lobe appears to be important for pitch discrimination and separating an auditory signal from a noise background.

<p>Anterior temporal lobe (A)</p> Signup and view all the answers

Damage in the visual association cortex in what hemisphere usually causes severe reading impairment?

<p>Left (B)</p> Signup and view all the answers

Damage to this part of the frontal lobes may cause a variety of impairments, including disturbed affect, attentional impairments, and difficulties initiating and maintaining behavior.

<p>Anterior frontal lobe (C)</p> Signup and view all the answers

What lobe is important for the perception and processing of auditory stimuli>

<p>Temporal (C)</p> Signup and view all the answers

Responsible for initiating most, if not all, skilled volitional movement

<p>Pyramidal system (D)</p> Signup and view all the answers

This is a diffuse system of subcortical structures and pathway arising from diverse locations in the CNS (primarily the BG) and projecting to cranial and spinal nerves

<p>Extra-pyramidal system (B)</p> Signup and view all the answers

This system is responsible for balance and orientation of the body in space and for maintaining general states of attention and alertness

<p>Vestibular-Reticular System (C)</p> Signup and view all the answers

A condition in which patients fail to recognize otherwise familiar stimuli in a sensory modality even though basic perception in that modality is preserved

<p>Agnosia (D)</p> Signup and view all the answers

Difficulty in carrying out sequences of volitional movements in the absence of weakness, paralysis, sensory loss, or incoordination in the muscles used for the movements.

<p>Apraxia (A)</p> Signup and view all the answers

This is the major source of blood to the brain.

<p>Internal carotid (C)</p> Signup and view all the answers

This artery supplies the upper and anterior frontal lobes and the anterior corpus callosum.

<p>Anterior cerebral artery (A)</p> Signup and view all the answers

This artery supplies the posterior frontal lobe, most of the parietal and temporal lobes, plus the thalamus and basal ganglia

<p>Middle cerebral artery (C)</p> Signup and view all the answers

Damage to this artery affects the calcarine cortex (Primary visual), thalamus, upper midbrain, and hippocampus. It can cause visual impairments, low pain tolerance, coma, movement disorder, and memory deficits

<p>Posterior cerebral artery (C)</p> Signup and view all the answers

This artery supplies the occipital lobe and the inferior temporal lobe.

<p>Posterior cerebral artery (C)</p> Signup and view all the answers

Damage to this artery can cause contralateral sensorimotor deficits, visual deficits, aphasia, apraxia, cognitive deficits

<p>Middle cerebral artery (B)</p> Signup and view all the answers

Ischemic is the most common form of stroke.

<p>True (A)</p> Signup and view all the answers

This structure supplies blood to the entire brain via cortical and central arteries. It provides collateral blood flow, equalizes pressure, and redundancy in case of occlusion

<p>Circle of Willis (A)</p> Signup and view all the answers

How can the blood brain barrier be broken down?

<p>Hypertension - high blood pressure Hyperosmolitity- high concentration of a substance can open the BBB Microwaves- exposure to microwaves open the BBB Radiation Infectious agents Trauma, Ischemia, inflammation, pressure</p> Signup and view all the answers

This artery supplies blood to the facial muscles, forehead, and oral, nasal, orbital cavities

<p>External cartoid (B)</p> Signup and view all the answers

What are 3 acute-onset diseases that can stabilize and improve over time?

<p>Abscesses Encephalitis Acute disseminated encephalomyelitis (ADEM) Stroke TBI</p> Signup and view all the answers

Nearly 50% of patients demonstrate cognitive impairments over time (memory, sustained attention, processing speed) with language difficulties being less common.

<p>MS (B)</p> Signup and view all the answers

What is the most frequent cause of dementia?

<p>Alzheimer's (C)</p> Signup and view all the answers

This progressive disease is caused by deterioration of dopamine-producing neurons in the BG (substantia nigra) and brainstem. Symptoms include resting tremors, bradykinesia, muscle rigidity, and postural instability.

<p>Parkinson's disease (C)</p> Signup and view all the answers

In the United States, what disease is second to Alzheimer's disease as a cause of dementia?

<p>Vascular disease (A)</p> Signup and view all the answers

Flashcards

Frontal Lobe Function

Responsible for planning and executing voluntary actions.

Temporal Lobe Function (Left)

Crucial for understanding language.

Temporal Lobe Function (Right)

Important for interpreting non-verbal signals.

Parietal Lobe Function

Processes touch, body awareness, and spatial info.

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Motor Cortex Function

Controls voluntary movements.

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Visual Cortex Damage (Left)

Can lead to severe reading impairment.

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Cerebellum Function

Controls balance and body posture.

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Agnosia

Inability to recognize familiar stimuli despite intact sensory perception.

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Apraxia

Difficulty performing sequential tasks, despite muscle control.

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Circle of Willis Function

Provides backup blood flow to the brain.

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Anterior Cerebral Artery Function

Supplies upper & anterior frontal lobes and corpus callosum.

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Middle Cerebral Artery Function

Supplies sensory and motor parts of the brain.

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Posterior Cerebral Artery Function

Supplies the occipital and inferior temporal lobes.

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Internal Carotid Artery Function

Supplies blood to the brain via the anterior and middle arteries.

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Vertebral & Basilar Arteries Function

Supplies the brain via the posterior cerebral artery.

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Blood-Brain Barrier Function

Protects the brain from harmful substances.

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External Carotid Artery Function

Supplies blood to face, head muscles and orbital cavities.

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Acute-Onset Neurological Disease Example

Conditions causing sudden neurological problems.

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Dementia Symptoms

Cognitive impairments like memory loss in patients.

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Parkinson's Disease Cause

Dopamine-producing neuron deterioration in specific brain areas.

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Dementia Common Cause

Alzheimer's disease is a major cause of dementia.

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Study Notes

Frontal Lobe

  • Responsible for planning and executing volitional behavior
  • Damage to the association cortex in the frontal lobes can disrupt position sense, cause visuospatial impairments, and affect affect, attention, behavior initiation, and maintenance

Temporal Lobe

  • The left temporal lobe is important for language comprehension
  • The right temporal lobe is important for interpreting complex nonverbal visuals and sounds
  • Damage to the temporal lobe association cortex can cause visual agnosia and distorted visual perceptions

Parietal Lobe

  • Important for perception, integration, and mediation of touch, body awareness, and visuospatial information
  • Damage to the association cortex in the parietal lobe can disrupt position sense and cause visuospatial impairments

Motor Cortex

  • Responsible for initiating most, if not all, skilled volitional movement
  • Damage to the primary motor cortex causes weakness or paralysis of muscle groups on the contralateral side of the body

Visual Cortex

  • Damage to the visual association cortex in the left hemisphere usually causes severe reading impairment

Cerebellum

  • This is a diffuse system of subcortical structures and pathway arising from diverse locations in the CNS (primarily the BG) and projecting to cranial and spinal nerves
  • Responsible for balance and orientation of the body in space and for maintaining general states of attention and alertness

Agnosia

  • A condition in which patients fail to recognize otherwise familiar stimuli in a sensory modality even though basic perception in that modality is preserved

Apraxia

  • Difficulty in carrying out sequences of volitional movements in the absence of weakness, paralysis, sensory loss, or incoordination in the muscles used for the movements

Circle of Willis

  • This is the major source of blood to the brain
  • It provides collateral blood flow, equalizes pressure, and redundancy in case of occlusion
  • The circle of Willis supplies blood to the entire brain via cortical and central arteries

Anterior Cerebral Artery

  • Supplies the upper and anterior frontal lobes and the anterior corpus callosum
  • Damage can cause contralateral lower limb weakness or paralysis

Middle Cerebral Artery

  • Supplies the posterior frontal lobe, most of the parietal and temporal lobes, plus the thalamus and basal ganglia
  • Damage can cause contralateral upper limb weakness or paralysis, impaired sensation, and aphasia (if left hemisphere is affected)

Posterior Cerebral Artery

  • Supplies the occipital lobe and the inferior temporal lobe
  • Damage can cause visual deficits, contralateral sensorimotor deficits, aphasia, apraxia, and cognitive deficits

Internal Carotid Artery

  • Supplies blood to the brain via the anterior and middle cerebral arteries

Vertebral and Basilar Arteries

  • Supplies blood to the brain via the posterior cerebral artery and other arteries

Blood Brain Barrier

  • Can be broken down by:
    • Hypertension
    • Inflammation
    • Trauma
    • Ischemia

External Carotid Artery

  • Supplies blood to the facial muscles, forehead, and oral, nasal, orbital cavities

Acute-Onset Neurological Diseases

  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
  • Guillain-Barré Syndrome (GBS)
  • Multiple Sclerosis (MS)

Dementia

  • Nearly 50% of patients demonstrate cognitive impairments over time (memory, sustained attention, processing speed) with language difficulties being less common
  • Most frequent cause of dementia is Alzheimer's disease

Parkinson's disease

  • Progressive disease caused by deterioration of dopamine-producing neurons in the BG (substantia nigra) and brainstem
  • Symptoms include resting tremors, bradykinesia, muscle rigidity, and postural instability
  • Second most frequent cause of dementia in the United States

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Test your knowledge on the brain's lobes, particularly focusing on the lobe responsible for planning and executing voluntary actions. This quiz will assess your understanding of the brain's functional regions and their roles in behavior.

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