M2: Neuropathologies
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Questions and Answers

This lobe is responsible for planning and executing volitional behavior.

  • Frontal (correct)
  • Temporal
  • Parietal
  • Occipital
  • This side of the temporal lobe appears to be important for the interpretation of complex nonverbal visual stimuli and for recognition and comprehension of nonverbal sounds, including receptive components of music.

  • Anterior temporal lobe
  • Right temporal lobe (correct)
  • Left temporal lobe
  • Association cortex
  • This lobe is important for perception, integration, and mediation of touch, body awareness, and visuospatial information.

  • Frontal
  • Temporal
  • Parietal (correct)
  • Occipital
  • Damage in the association cortex in either of these lobes typically disturbs position sense and causes various visuospatial impairments.

    <p>Parietal</p> Signup and view all the answers

    Damage in the association cortex adjacent to the visual cortex in either hemisphere typically causes visual agnosia and distorted visual perceptions

    <p>Occipital</p> Signup and view all the answers

    Damage to the primary motor cortex causes weakness or paralysis of muscle groups on what side of the body?

    <p>Contralateral</p> Signup and view all the answers

    This portion of the temporal lobe appears to be important for pitch discrimination and separating an auditory signal from a noise background.

    <p>Anterior temporal lobe</p> Signup and view all the answers

    Damage in the visual association cortex in what hemisphere usually causes severe reading impairment?

    <p>Left</p> Signup and view all the answers

    Damage to this part of the frontal lobes may cause a variety of impairments, including disturbed affect, attentional impairments, and difficulties initiating and maintaining behavior.

    <p>Anterior frontal lobe</p> Signup and view all the answers

    What lobe is important for the perception and processing of auditory stimuli>

    <p>Temporal</p> Signup and view all the answers

    Responsible for initiating most, if not all, skilled volitional movement

    <p>Pyramidal system</p> Signup and view all the answers

    This is a diffuse system of subcortical structures and pathway arising from diverse locations in the CNS (primarily the BG) and projecting to cranial and spinal nerves

    <p>Extra-pyramidal system</p> Signup and view all the answers

    This system is responsible for balance and orientation of the body in space and for maintaining general states of attention and alertness

    <p>Vestibular-Reticular System</p> Signup and view all the answers

    A condition in which patients fail to recognize otherwise familiar stimuli in a sensory modality even though basic perception in that modality is preserved

    <p>Agnosia</p> Signup and view all the answers

    Difficulty in carrying out sequences of volitional movements in the absence of weakness, paralysis, sensory loss, or incoordination in the muscles used for the movements.

    <p>Apraxia</p> Signup and view all the answers

    This is the major source of blood to the brain.

    <p>Internal carotid</p> Signup and view all the answers

    This artery supplies the upper and anterior frontal lobes and the anterior corpus callosum.

    <p>Anterior cerebral artery</p> Signup and view all the answers

    This artery supplies the posterior frontal lobe, most of the parietal and temporal lobes, plus the thalamus and basal ganglia

    <p>Middle cerebral artery</p> Signup and view all the answers

    Damage to this artery affects the calcarine cortex (Primary visual), thalamus, upper midbrain, and hippocampus. It can cause visual impairments, low pain tolerance, coma, movement disorder, and memory deficits

    <p>Posterior cerebral artery</p> Signup and view all the answers

    This artery supplies the occipital lobe and the inferior temporal lobe.

    <p>Posterior cerebral artery</p> Signup and view all the answers

    Damage to this artery can cause contralateral sensorimotor deficits, visual deficits, aphasia, apraxia, cognitive deficits

    <p>Middle cerebral artery</p> Signup and view all the answers

    Ischemic is the most common form of stroke.

    <p>True</p> Signup and view all the answers

    This structure supplies blood to the entire brain via cortical and central arteries. It provides collateral blood flow, equalizes pressure, and redundancy in case of occlusion

    <p>Circle of Willis</p> Signup and view all the answers

    How can the blood brain barrier be broken down?

    <p>Hypertension - high blood pressure Hyperosmolitity- high concentration of a substance can open the BBB Microwaves- exposure to microwaves open the BBB Radiation Infectious agents Trauma, Ischemia, inflammation, pressure</p> Signup and view all the answers

    This artery supplies blood to the facial muscles, forehead, and oral, nasal, orbital cavities

    <p>External cartoid</p> Signup and view all the answers

    What are 3 acute-onset diseases that can stabilize and improve over time?

    <p>Abscesses Encephalitis Acute disseminated encephalomyelitis (ADEM) Stroke TBI</p> Signup and view all the answers

    Nearly 50% of patients demonstrate cognitive impairments over time (memory, sustained attention, processing speed) with language difficulties being less common.

    <p>MS</p> Signup and view all the answers

    What is the most frequent cause of dementia?

    <p>Alzheimer's</p> Signup and view all the answers

    This progressive disease is caused by deterioration of dopamine-producing neurons in the BG (substantia nigra) and brainstem. Symptoms include resting tremors, bradykinesia, muscle rigidity, and postural instability.

    <p>Parkinson's disease</p> Signup and view all the answers

    In the United States, what disease is second to Alzheimer's disease as a cause of dementia?

    <p>Vascular disease</p> Signup and view all the answers

    Study Notes

    Frontal Lobe

    • Responsible for planning and executing volitional behavior
    • Damage to the association cortex in the frontal lobes can disrupt position sense, cause visuospatial impairments, and affect affect, attention, behavior initiation, and maintenance

    Temporal Lobe

    • The left temporal lobe is important for language comprehension
    • The right temporal lobe is important for interpreting complex nonverbal visuals and sounds
    • Damage to the temporal lobe association cortex can cause visual agnosia and distorted visual perceptions

    Parietal Lobe

    • Important for perception, integration, and mediation of touch, body awareness, and visuospatial information
    • Damage to the association cortex in the parietal lobe can disrupt position sense and cause visuospatial impairments

    Motor Cortex

    • Responsible for initiating most, if not all, skilled volitional movement
    • Damage to the primary motor cortex causes weakness or paralysis of muscle groups on the contralateral side of the body

    Visual Cortex

    • Damage to the visual association cortex in the left hemisphere usually causes severe reading impairment

    Cerebellum

    • This is a diffuse system of subcortical structures and pathway arising from diverse locations in the CNS (primarily the BG) and projecting to cranial and spinal nerves
    • Responsible for balance and orientation of the body in space and for maintaining general states of attention and alertness

    Agnosia

    • A condition in which patients fail to recognize otherwise familiar stimuli in a sensory modality even though basic perception in that modality is preserved

    Apraxia

    • Difficulty in carrying out sequences of volitional movements in the absence of weakness, paralysis, sensory loss, or incoordination in the muscles used for the movements

    Circle of Willis

    • This is the major source of blood to the brain
    • It provides collateral blood flow, equalizes pressure, and redundancy in case of occlusion
    • The circle of Willis supplies blood to the entire brain via cortical and central arteries

    Anterior Cerebral Artery

    • Supplies the upper and anterior frontal lobes and the anterior corpus callosum
    • Damage can cause contralateral lower limb weakness or paralysis

    Middle Cerebral Artery

    • Supplies the posterior frontal lobe, most of the parietal and temporal lobes, plus the thalamus and basal ganglia
    • Damage can cause contralateral upper limb weakness or paralysis, impaired sensation, and aphasia (if left hemisphere is affected)

    Posterior Cerebral Artery

    • Supplies the occipital lobe and the inferior temporal lobe
    • Damage can cause visual deficits, contralateral sensorimotor deficits, aphasia, apraxia, and cognitive deficits

    Internal Carotid Artery

    • Supplies blood to the brain via the anterior and middle cerebral arteries

    Vertebral and Basilar Arteries

    • Supplies blood to the brain via the posterior cerebral artery and other arteries

    Blood Brain Barrier

    • Can be broken down by:
      • Hypertension
      • Inflammation
      • Trauma
      • Ischemia

    External Carotid Artery

    • Supplies blood to the facial muscles, forehead, and oral, nasal, orbital cavities

    Acute-Onset Neurological Diseases

    • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
    • Guillain-Barré Syndrome (GBS)
    • Multiple Sclerosis (MS)

    Dementia

    • Nearly 50% of patients demonstrate cognitive impairments over time (memory, sustained attention, processing speed) with language difficulties being less common
    • Most frequent cause of dementia is Alzheimer's disease

    Parkinson's disease

    • Progressive disease caused by deterioration of dopamine-producing neurons in the BG (substantia nigra) and brainstem
    • Symptoms include resting tremors, bradykinesia, muscle rigidity, and postural instability
    • Second most frequent cause of dementia in the United States

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    Description

    Test your knowledge on the brain's lobes, particularly focusing on the lobe responsible for planning and executing voluntary actions. This quiz will assess your understanding of the brain's functional regions and their roles in behavior.

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