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ENDOCRINE part 1

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Christy Forwood
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30 Questions

Bradykinin synthesises which of the following ?

Nitric Oxide

Which type of GPCR does Angiotensin II most commonly act via ?

Gq

The posterior pituitary is divided into how many segments ?

2

Which layer of the adrenal cortex produces cortisol?

Zona fasciculata

What is the primary hormone produced by the Zona glomerulosa?

Aldosterone

What stimulates the biosynthesis of aldosterone in the Zona glomerulosa?

Angiotensin II

Which adrenal hormone is involved in mineralocorticoid activity?

Aldosterone

In which layer of the adrenal cortex is androgen produced ?

Zona reticularis

What are the main adrenal androgens?

DHEA and androstenedione

What is the consequence of too much aldosterone?

Hypertension and hypokalemia

In which zone of the adrenal gland is glucocorticoid excess observed?

Zona fasciculata

What hormone is released by adrenal medullary cells in response to stress?

Adrenaline

Which disease is characterised by hormonal overproduction in the Zona glomerulosa of the adrenal glands?

Conn's syndrome

Where is thyrotropin releasing hormone (TRH) produced?

Hypothalamus

The thyroid gland is formed from thickening of what ?

Endoderm

Eicosanoids are derived from what ?

Fatty acids

Which of the following is true in regards to receptor antagonists ?

Stimulates up-regulation of receptors

Which of the following is true ?

GH is highest during the night and cortisol is highest during the morning

Which of the following is a sub-section of the anterior pituitary gland ?

Pars intermedia

What is the primary function of the hormones stored in the posterior pituitary gland?

Conservation of body water

Which nuclei give rise to terminals that are found in the posterior pituitary gland?

Supraoptic and paraventricular nuclei

Which of the following reactions does aromatase catalyse in steroidogenesis ?

Conversion of androstenedione into estrone

Which hormone is formed from monodeiodination of T4 in both the thyroid and peripheral tissues?

T3

What is the main second messenger involved in the mechanism of action of TSH receptors to stimulate thyroid hormone release?

cAMP

Which system does thyroid hormone mimic the actions of?

Sympathetic nervous system

What is the primary function of progesterone during the menstrual cycle?

Inhibits uterine contractions

What is the typical duration of the follicular/proliferative phase of the menstrual cycle?

14-21 days

What is the role of FSH during the follicular/proliferative phase of the menstrual cycle?

All of the above

FSH stimulates which of the following ?

Granulosa cells in women

Which cells produce parathyroid ?

Chief cells

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