30 Questions
Bradykinin synthesises which of the following ?
Nitric Oxide
Which type of GPCR does Angiotensin II most commonly act via ?
Gq
The posterior pituitary is divided into how many segments ?
2
Which layer of the adrenal cortex produces cortisol?
Zona fasciculata
What is the primary hormone produced by the Zona glomerulosa?
Aldosterone
What stimulates the biosynthesis of aldosterone in the Zona glomerulosa?
Angiotensin II
Which adrenal hormone is involved in mineralocorticoid activity?
Aldosterone
In which layer of the adrenal cortex is androgen produced ?
Zona reticularis
What are the main adrenal androgens?
DHEA and androstenedione
What is the consequence of too much aldosterone?
Hypertension and hypokalemia
In which zone of the adrenal gland is glucocorticoid excess observed?
Zona fasciculata
What hormone is released by adrenal medullary cells in response to stress?
Adrenaline
Which disease is characterised by hormonal overproduction in the Zona glomerulosa of the adrenal glands?
Conn's syndrome
Where is thyrotropin releasing hormone (TRH) produced?
Hypothalamus
The thyroid gland is formed from thickening of what ?
Endoderm
Eicosanoids are derived from what ?
Fatty acids
Which of the following is true in regards to receptor antagonists ?
Stimulates up-regulation of receptors
Which of the following is true ?
GH is highest during the night and cortisol is highest during the morning
Which of the following is a sub-section of the anterior pituitary gland ?
Pars intermedia
What is the primary function of the hormones stored in the posterior pituitary gland?
Conservation of body water
Which nuclei give rise to terminals that are found in the posterior pituitary gland?
Supraoptic and paraventricular nuclei
Which of the following reactions does aromatase catalyse in steroidogenesis ?
Conversion of androstenedione into estrone
Which hormone is formed from monodeiodination of T4 in both the thyroid and peripheral tissues?
T3
What is the main second messenger involved in the mechanism of action of TSH receptors to stimulate thyroid hormone release?
cAMP
Which system does thyroid hormone mimic the actions of?
Sympathetic nervous system
What is the primary function of progesterone during the menstrual cycle?
Inhibits uterine contractions
What is the typical duration of the follicular/proliferative phase of the menstrual cycle?
14-21 days
What is the role of FSH during the follicular/proliferative phase of the menstrual cycle?
All of the above
FSH stimulates which of the following ?
Granulosa cells in women
Which cells produce parathyroid ?
Chief cells
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