Bone Health Assessment and Diagnosis Quiz

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Questions and Answers

What laboratory tests are used to assess bone health?

FBC, bone profile, renal profile, PTH, and vitamin D (correct)

Lipid profile, liver function tests, and thyroid function tests

Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and rheumatoid factor

Blood glucose, hemoglobin A1c, and insulin levels

What is the purpose of a DXA scan in assessing bone health?

To determine the age of menopause

To measure muscle strength

To assess joint swelling

To quantify the Bone Mineral Density (BMD) and produce a T-score (correct)

What does a T-score in the context of osteoporosis refer to?

The amount of bone pain experienced by the individual

The measurement of muscle strength in relation to bone density

The ratio of calcium to phosphorus in the bones

The number of standard deviations from the mean Bone Mineral Density (BMD) of a young adult reference population (correct)

Which of the following is NOT included in bone health assessment?

Lung function tests Signup and view all the answers

What laboratory test is used to assess parathyroid function in bone health assessment?

Renal profile Signup and view all the answers

In the context of bone health assessment, what does a DXA scan primarily quantify?

Bone mineral density Signup and view all the answers

Which factor would NOT be a consideration for pharmacological treatment of osteoporosis in postmenopausal women and men aged 50 years and over?

10-year probability of a major osteoporosis-related fracture <20% Signup and view all the answers

How do most osteoporosis medications work?

By inhibiting osteoclastic bone resorption Signup and view all the answers

Which medication primarily stimulates osteoblastic bone formation?

Teriparatide Signup and view all the answers

Which type of medication is considered the most cost-effective option for osteoporosis treatment?

Bisphosphonates Signup and view all the answers

How are oral bisphosphonates typically administered?

On an empty stomach 30 minutes before food Signup and view all the answers

What is the primary function of antiresorptive medication in osteoporosis treatment?

Inhibiting osteoclastic bone resorption Signup and view all the answers

At what age should pharmacological treatment be considered for osteoporosis in men and women?

50 years and over Signup and view all the answers

What is the T-score threshold for considering pharmacological treatment in osteoporosis?

<−2.5 at the femoral neck or lumbar spine Signup and view all the answers

Which medication is often the first-line agent used for osteoporosis treatment due to its cost-effectiveness?

Alendronate Signup and view all the answers

What is the primary effect of anabolic drugs in osteoporosis treatment?

Stimulating bone formation Signup and view all the answers

Study Notes

Laboratory Tests for Bone Health

Bone Mineral Density (BMD): Measured by Dual-energy X-ray Absorptiometry (DXA) scan.

DXA Scan

Primarily quantifies bone density, specifically at the hip and spine.

T-Score

Represents bone density compared to a young, healthy adult (peak bone mass).

Bone Health Assessment Components

Dietary intake
Physical activity
Medical history
Family history
Medications
Lifestyle factors

Parathyroid Function Assessment

Parathyroid hormone (PTH) levels are measured through laboratory tests.

Pharmacological Treatment Considerations

Age
Fracture history
Bone mineral density (BMD)
Underlying medical conditions

Osteoporosis Medication Mechanisms

Antiresorptive agents: Inhibit bone resorption (breakdown).
Anabolic agents: Stimulate bone formation.

Stimulates Osteoblastic Bone Formation

Teriparatide (Forteo) is the primary medication for stimulating osteoblastic bone formation.

Most Cost-Effective Option

Bisphosphonates are considered the most cost-effective option for osteoporosis treatment.

Oral Bisphosphonate Administration

Weekly, monthly, or quarterly doses are typically administered.

Antiresorptive Medication Function

Slows down bone loss by inhibiting bone resorption.

Pharmacological Treatment Age

Considered for men and women aged 50 years and over.

T-Score Threshold for Pharmacological Treatment

T-score of -2.5 or lower.

First-Line Osteoporosis Treatment

Bisphosphonates are often the first-line agent due to cost-effectiveness.

Anabolic Drug Effect

Increase bone mass by promoting bone formation.

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Description

Test your knowledge about bone health assessment, including inquiries and laboratory tests, for diagnosing osteoporosis. Learn about the DXA scan and T-score in quantifying bone mineral density (BMD).