Bone Growth and Remodeling Process

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Questions and Answers

Which process involves the formation of bone through the deposition of osteoid tissue by osteoblasts on a mesenchymal surface?

  • Trabecular ossification
  • Periosteal ossification
  • Intramembranous ossification (correct)
  • Endochondral ossification

What is the characteristic of the bone formed through intramembranous ossification?

  • Production of long bones like femur
  • Presence of a marrow cavity
  • Conversion of spongy bone to compact bone
  • Formation of spongy bone first (correct)

During endochondral ossification, what is the main role of the trabeculae?

  • Conversion to fibrous periosteum
  • Formation of the marrow cavity
  • Entrapment of osteocytes
  • Creation of spongy bone (correct)

Which type of bone formation process leads to the production of flat bones like the skull and clavicle?

<p>Intramembranous ossification (B)</p> Signup and view all the answers

What is the function of osteoblasts in bone development?

<p>Bone formation (D)</p> Signup and view all the answers

Which structure is involved in perpetuating spongy bone formation in the middle layer during intramembranous ossification?

<p>Osteocytes (A)</p> Signup and view all the answers

Which structure is responsible for bone elongation in childhood and adolescence?

<p>Metaphysis (B)</p> Signup and view all the answers

What type of bone tissue is primarily found in the epiphyses of long bones during infancy and childhood?

<p>Spongy bone (B)</p> Signup and view all the answers

Which part of a child's bone has an enlarged primary marrow cavity and a distal secondary marrow cavity appearance?

<p>Metaphysis (C)</p> Signup and view all the answers

In which type of bone formation, vascular invasion occurs leading to the formation of primary and secondary marrow cavities?

<p>Endochondral ossification (D)</p> Signup and view all the answers

During adulthood, which structure in bones closes to signal the end of bone growth and elongation?

<p>Epiphyseal plate (D)</p> Signup and view all the answers

Which part of the bone contains a single marrow cavity in adult bones?

<p>Diaphysis (B)</p> Signup and view all the answers

What is the function of epiphyseal plates in bones?

<p>Allow for bone growth in length (D)</p> Signup and view all the answers

Which cells are responsible for laying down new bone matrix in layers parallel to the bone surface?

<p>Osteoblasts (B)</p> Signup and view all the answers

Abnormal calcification may occur in all of the following locations EXCEPT:

<p>Heart (D)</p> Signup and view all the answers

Which enzyme is responsible for digesting collagen during mineral resorption in bones?

<p>Acid phosphatase (D)</p> Signup and view all the answers

What is the normal calcium concentration in blood plasma?

<p>9.2 to 10.4 mg/dL (D)</p> Signup and view all the answers

Which hormone is primarily responsible for stimulating calcium resorption from bone?

<p>Parathyroid hormone (D)</p> Signup and view all the answers

In which bone growth process do bones increase in width throughout life?

<p>Appositional growth (B)</p> Signup and view all the answers

'Wolff's law' states that:

<p>'Bone density determined by mechanical stresses' (A)</p> Signup and view all the answers

What is the primary function of mineral resorption in bones?

<p>To release minerals into the blood (B)</p> Signup and view all the answers

Which component of bone plays a critical role in neuron communication?

<p>Calcium (D)</p> Signup and view all the answers

Flashcards

Intramembranous ossification

The process of bone formation where osteoblasts lay down osteoid tissue on a mesenchymal surface.

Characteristic of intramembranous ossification

Spongy bone forms first.

Trabeculae role in endochondral ossification

The main role of trabeculae in endochondral ossification is to create spongy bone.

Bone formation process for flat bones

Intramembranous ossification produces flat bones.

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Osteoblasts function

Osteoblasts are cells responsible for bone formation.

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Osteocytes role in intramembranous ossification

Osteocytes are involved in the ongoing formation of spongy bone in the middle layer during intramembranous ossification.

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Metaphysis function

The metaphysis is responsible for bone elongation during childhood and adolescence.

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Bone tissue in epiphyses

Spongy bone is primarily found in the epiphyses of long bones during infancy and childhood.

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Metaphysis structure

The metaphysis has an enlarged primary marrow cavity and a distal secondary marrow cavity.

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Vascular invasion in endochondral ossification

Vascular invasion occurs in endochondral ossification, leading to primary and secondary marrow cavities.

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Epiphyseal plate closure

The epiphyseal plate closes during adulthood, signaling the end of bone growth.

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Diaphysis structure

The diaphysis has a single marrow cavity in adult bones.

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Epiphyseal plates function

Epiphyseal plates allow for bone growth in length.

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Osteoblast function

Osteoblasts are cells responsible for laying down new bone matrix.

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Locations of abnormal calcification

Abnormal calcification can occur in many locations, but not in the heart.

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Enzyme responsible for collagen digestion

Acid phosphatase is the enzyme responsible for digesting collagen during mineral resorption.

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Normal blood calcium concentration

The normal calcium concentration in blood plasma is 9.2 to 10.4 mg/dL.

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Hormone responsible for calcium resorption

Parathyroid hormone stimulates calcium resorption from bone.

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Appositional bone growth

Appositional growth is the process by which bones increase in width throughout life.

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Wolff's Law

Wolff's Law states that bone density is determined by mechanical stresses.

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Function of mineral resorption

The primary function of mineral resorption in bones is to release minerals into the blood.

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Calcium role in bone

Calcium is a critical component of bone that plays a role in neuron communication.

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