Bone Fracture Types

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Questions and Answers

In the context of bone fracture healing, which statement best articulates the mechanistic divergence between primary and secondary bone healing?

  • Secondary bone healing is characterized by a complete absence of inflammatory and reparative phases, unlike primary bone healing which requires an initial inflammatory response.
  • Primary bone healing achieves osseous consolidation via direct bone remodeling across the fracture line under conditions of rigid stabilization, contrasting with secondary bone healing, which involves callus formation under less rigid conditions. (correct)
  • Primary bone healing necessitates callus formation as a precursor to bony union, while secondary bone healing preferentially proceeds through direct remodeling by osteoclasts and osteoblasts.
  • Secondary bone healing depends on rigid stabilization to prevent callus formation, whereas primary bone healing relies on micromotion at the fracture site to stimulate callus development.

Which of the following fracture types is most likely to present with a high risk of infection, thereby necessitating surgical intervention to mitigate potential complications?

  • An incomplete, greenstick fracture of the ulna, commonly observed in pediatric patients.
  • A comminuted fracture of the femur, characterized by multiple bone fragments but with the skin intact.
  • An open (compound) fracture of the radius, where the bone has breached the skin barrier. (correct)
  • A closed, simple fracture of the tibia, resulting from a low-energy sports injury.

Given the complex interplay of mechanical forces and bone characteristics, which fracture type would be most indicative of potential child abuse, especially in pre-ambulatory children?

  • A linear fracture of the humerus, consistent with a direct blow during contact sports.
  • A spiral fracture of the tibia in a non-weight-bearing child, without a plausible accidental mechanism. (correct)
  • A transverse fracture of the femur resulting from a fall from a significant height.
  • An oblique fracture of the radius, sustained during a playground accident.

Considering the intricate process of bone remodeling, what cellular and molecular events critically determine the progression of bone strength after a fracture, distinguishing between primary and secondary bone healing?

<p>The ratio of osteoclast-mediated resorption to osteoblast-mediated deposition, alongside the temporal expression of RANKL and OPG, dictates bone strength restoration. (A)</p> Signup and view all the answers

In evaluating a patient presenting with a pathologic fracture secondary to underlying metabolic derangement, which pre-existing condition would most dramatically alter bone's mechanical competence?

<p>Advanced osteoporosis complicated by long-term glucocorticoid therapy. (D)</p> Signup and view all the answers

In the context of joint dislocations, which statement best encapsulates the biomechanical and neurovascular risks associated with a glenohumeral dislocation?

<p>Glenohumeral dislocations may compromise the axillary nerve, potentially leading to deltoid paralysis and sensory deficits, alongside potential injury to the shoulder capsule. (D)</p> Signup and view all the answers

Given the complex interplay of forces and joint structures, which dislocation is most likely to result from forced abduction and present a heightened risk of avascular necrosis?

<p>Anterior hip dislocation, disrupting blood supply to the femoral head. (C)</p> Signup and view all the answers

Considering the microstructural environment of tendons and ligaments, what key compositional variance critically influences their distinct functional attributes?

<p>Tendons, characterized by a parallel arrangement of collagen fibers with minimal elastin, primarily transmit unidirectional force, whereas ligaments have a more varied collagen orientation with higher elastin content, allowing flexibility and joint stability. (B)</p> Signup and view all the answers

During the healing phase post-tendon or ligament rupture, what advanced therapeutic intervention is MOST critical in achieving optimal restoration?

<p>Precisely calibrated mechanical loading to stimulate collagen alignment and promote enthesis regeneration. (A)</p> Signup and view all the answers

Considering the intricate cascade of pain signal transduction, what pharmacological intervention would MOST effectively target neuropathic pain arising from nerve compression due to a herniated disc?

<p>Voltage-gated calcium channel ligands (e.g., gabapentin, pregabalin) to modulate neuronal excitability and reduce ectopic firing. (C)</p> Signup and view all the answers

In the context of pain modulation, which neurophysiological mechanism accounts for the phenomenon of perceptual dominance?

<p>Inhibition of pain signals in one area by intense pain signals from another, possibly due to shared neural pathways or central modulation. (B)</p> Signup and view all the answers

When developing a comprehensive, multimodal treatment regimen for chronic lower back pain (LBP), what critical consideration should guide the selection and sequencing of interventions to optimize patient outcomes?

<p>Targeting underlying pain mechanism with pharmacological and non-pharmacological strategies alongside functional restoration and psychosocial support. (D)</p> Signup and view all the answers

In a patient presenting with suspected primary osteoporosis, what specific bone quality parameters, beyond bone mineral density (BMD), would be most valuable in predicting fracture risk and guiding personalized treatment strategies?

<p>Trabecular bone score (TBS) to assess microarchitecture, coupled with serum levels of C-terminal telopeptide (CTX) and procollagen type 1 N-terminal propeptide (P1NP) for bone turnover assessment. (C)</p> Signup and view all the answers

Given the complex interplay of hormonal regulation in bone metabolism, what specific intervention would selectively counteract increased osteoclast activity in postmenopausal osteoporosis?

<p>Selective estrogen receptor modulators (SERMs) to mimic estrogen's bone-protective effects. (B)</p> Signup and view all the answers

In the context of osteomalacia pathophysiology, what specific mechanism explains the generalized bone pain?

<p>Accumulation of unmineralized osteoid stimulating mechanoreceptors and causing pain. (A)</p> Signup and view all the answers

How do the pathophysiological mechanisms of calcipenic and phosphopenic rickets differ, and how would these differences manifest clinically and diagnostically?

<p>Calcipenic rickets is due to insufficient vitamin D and or calcium intake, causing hypocalcemia, secondary hyperparathyroidism, and bone demineralization, whereas phosphopenic rickets is caused by renal phosphate wasting. (D)</p> Signup and view all the answers

In a patient diagnosed with osteomyelitis, what advanced imaging modality would discriminate between sequestrum and involucrum formation, guiding surgical debridement?

<p>Magnetic resonance imaging (MRI) with gadolinium contrast to delineate the extent of bone and soft tissue infection and assess vascularity. (D)</p> Signup and view all the answers

What factors are the most critical determinants in the pathogenesis of acute hematogenous osteomyelitis in children versus adults?

<p>The presence or absence of patent transphyseal vessels dictates the likelihood of epiphyseal involvement and subsequent joint destruction. (D)</p> Signup and view all the answers

Given the heterogeneity of bone tumors what features serve to differentiate osteosarcoma from Ewing sarcoma in adolescents?

<p>The histological features serve to differentiate osteosarcoma from Ewing sarcoma, with osteosarcoma arising from malignant bone tumor. (B)</p> Signup and view all the answers

During the progressive stages of osteoarthritis (OA), what complex interplay of cellular and molecular events drives irreversible articular cartilage degradation and aberrant subchondral bone remodeling?

<p>Chondrocyte dysfunction, coupled with upregulated matrix metalloproteinase (MMP) activity and inflammatory cytokine production, resulting in ECM degradation and altered bone turnover. (A)</p> Signup and view all the answers

Considering the multifaceted pathophysiology of osteoarthritis, what therapeutic intervention is most effective to halt the progressive degradation of articular cartilage?

<p>There is currently no intervention that has shown a strong record against halt the progressive degradation of articular cartilage. (B)</p> Signup and view all the answers

When approaching a patient presenting with suspected rheumatoid arthritis (RA), what serologic and inflammatory markers would provide the strongest evidence?

<p>Positive rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPAs), coupled with elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). (A)</p> Signup and view all the answers

How is the mechanism of pannus formation related to joint destruction and the resulting physical manifestations in Rheumatoid Arthritis?

<p>Pannus formation and joint destruction manifests by a stiffed joint with limited ROM. (B)</p> Signup and view all the answers

What pathophysiological event is directly responsible for acute inflammation and pain in gout?

<p>Neutrophils accumulate and engulf MSU crystals, which releases phagolysosomal contents, causing inflammation and exacerbating tissue damage. (A)</p> Signup and view all the answers

What distinguishes gout from pseudogout?

<p>Gout is commonly due to elevated uritic acid. (D)</p> Signup and view all the answers

Given the significance of genetics in disorders such as gout and rheumatoid arthritis, what role does precision medicine play in the understanding of these conditions?

<p>Genome-wide association studies (GWAS) indicate links/SNPs. (A)</p> Signup and view all the answers

How does Long Covid (post-acute sequelae of COVID-19) most likely impact musculoskeletal system?

<p>More Long Covid (post-acute sequelae of COVID-19) patient report musculoskeletal symptoms than other patient population. (B)</p> Signup and view all the answers

What is a good way to distinguish Long Covid (post-acute sequelae of COVID-19) and Lyme's.

<p>There is no specific symptom that separates Long Covid (post-acute sequelae of COVID-19). (B)</p> Signup and view all the answers

What features allow osteocytes to remain fully functioning?

<p>Communication/mechanoreceptors. (D)</p> Signup and view all the answers

How does diabetes promote/impact arthritis?

<p>It changes and impairs proteoglycans matrix. (C)</p> Signup and view all the answers

How do rheumatoid factors support joint dysfunction?

<p>It signals for inflammation/activates synoviocytes. (E)</p> Signup and view all the answers

What can contribute to osteomalacia and vitamin D deficiency?

<p>Bariatric surgery, genetics and diet intake. (A)</p> Signup and view all the answers

Where do infections deposit in osteomyelitis?

<p>Infections commonly deposit in metaphysis. (B)</p> Signup and view all the answers

Rank the likelihood of infections in osteomyelitis?

<p>Hematogenous/contagious most common. (B)</p> Signup and view all the answers

From Long Covid which of these is most common?

<p>Muscle weakness long term inflammatory chronic widespread myalgia. (C)</p> Signup and view all the answers

Which are bone tumor classification?

<p>Myelogenic to bone/cartilage etc. (C)</p> Signup and view all the answers

What is the hallmark of bone tumor aggression?

<p>Periosteal and bone destruction vs bone formation. (A)</p> Signup and view all the answers

Considering the multifaceted nature of nociception, which statement best encapsulates the role of Aδ and C fibers in the transmission of pain signals from a peripheral injury site to the central nervous system?

<p>Aδ fibers, being large and myelinated, predominantly convey initial sharp, well-localized pain via the anterior spinothalamic tract, whereas C fibers transmit sustained, diffuse, and aching pain through the lateral spinothalamic tract. (A)</p> Signup and view all the answers

In the context of pain modulation, consider the complex interaction between descending inhibitory pathways and neurotransmitters. Which of the following statements best explains the role of endogenous opioids in reducing pain transmission?

<p>Endogenous opioids bind to mu (μ), kappa (k), and delta (δ) receptors on neurons in the periphery, spinal cord, and brain, inhibiting ion channels and preventing the release of excitatory neurotransmitters. (D)</p> Signup and view all the answers

Given the interplay of mechanical forces and bone characteristics, which injury would most strongly suggest an underlying pathological condition affecting bone integrity, especially in the absence of significant trauma?

<p>A comminuted fracture of the vertebral body during a fall from standing height in an elderly patient. (C)</p> Signup and view all the answers

When considering fracture patterns in pediatric patients, which type is MOST indicative of non-accidental trauma, necessitating immediate safeguarding measures and a thorough investigation into the child's living environment?

<p>A spiral fracture of the femur in a non-ambulatory infant. (A)</p> Signup and view all the answers

Within the context of articular cartilage degradation in osteoarthritis (OA), which of the following elements most intricately orchestrates the matrix metalloproteinase (MMP)-mediated breakdown of type II collagen, leading to irreversible joint damage?

<p>The imbalance between the synthesis of tissue inhibitors of metalloproteinases (TIMPs) and MMPs, favoring MMP activity and cartilage degradation. (C)</p> Signup and view all the answers

In scenarios of suspected primary hyperparathyroidism contributing to osteoporosis, what intervention most directly addresses the underlying pathophysiology of increased osteoclastic bone resorption, thus mitigating skeletal fragility?

<p>Surgical parathyroidectomy to remove the hyperfunctioning parathyroid adenoma. (C)</p> Signup and view all the answers

What specific pathomechanism is most immediately responsible for the diffuse bone pain experienced by individuals afflicted with osteomalacia, thereby distinguishing it from other metabolic bone disorders?

<p>The accumulation of non-mineralized osteoid, leading to distention of the periosteum and activation of pain-sensitive nerve endings. (D)</p> Signup and view all the answers

In contrasting the etiologies of calcipenic and phosphopenic rickets, which statement best captures the fundamental distinction in their respective pathophysiologies and downstream clinical or diagnostic ramifications?

<p>Calcipenic rickets arises from insufficient dietary intake or impaired absorption of calcium, leading to secondary hyperparathyroidism and phosphate wasting, whereas phosphopenic rickets involves primary renal phosphate wasting. (B)</p> Signup and view all the answers

To optimally differentiate between a sequestrum and involucrum in osteomyelitis, which imaging modality should be employed to provide the highest resolution to observe the vascular supply to guide surgical planning?

<p>Magnetic resonance imaging (MRI) with gadolinium contrast, due to its ability to delineate soft tissue involvement and assess vascularity. (D)</p> Signup and view all the answers

Concerning the pathogenesis of acute hematogenous osteomyelitis, what delineates the most critical difference influencing the infectious pathway between pediatric and adult populations?

<p>Children's unique metaphyseal vascular structure allows bacterial seeding and proliferation, while adults more commonly present with vertebral involvement due to compromised circulation from degenerative changes. (A)</p> Signup and view all the answers

How might precision medicine improve the understanding of genetics in the pathology of disorders like rheumatoid arthritis (RA) and gout?

<p>By identifying specific genetic mutations and variations within individuals, allowing tailoring of therapeutic regimens targeted to the patient's distinct molecular profile, maximizing efficacy and minimizing adverse events. (D)</p> Signup and view all the answers

Considering the intricate balance of osteoblastic and osteoclastic activity, which of the following best describes the effect of estrogen on bone homeostasis in postmenopausal women?

<p>Estrogen deficiency accelerates bone resorption by increasing osteoclast activity, mediated by heightened expression of RANKL and pro-inflammatory cytokines, with decreased OPG production. (D)</p> Signup and view all the answers

In the context of hip dislocations, especially those resulting from high-energy trauma, which vascular structure is MOST vulnerable to injury?

<p>The medial femoral circumflex artery (MFCA), as it provides the major blood supply to the femoral head. (B)</p> Signup and view all the answers

What cellular mechanism explains the primary difference between bone spurs of osteoarthritis and bone formation in osteomalacia?

<p>Bone spurs (osteophytes) are disorganized bone growth due to normal bone remodeling to compensate for degradation of articular cartilage, while unmineralized bone matrix accumulates in osteomalacia due to inadequate mineralization. (D)</p> Signup and view all the answers

What are the diagnostic criteria that are used to differentiate osteosarcoma from Ewing sarcoma in adolescents?

<p>Microscopic examination, where osteosarcoma contains osteoid tissue while Ewing sarcoma is composed of small round blue cells. (D)</p> Signup and view all the answers

Flashcards

Complete Fracture

Bone is broken entirely into two or more separate pieces.

Incomplete Fracture

Partial bone damage due to bending or lower-impact force.

Open (Compound) Fracture

Bone breaks through the skin, increasing infection risk.

Closed (Simple) Fracture

Bone breaks but does not puncture the skin.

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Comminuted Fracture

Severe trauma causing bone to break into multiple fragments.

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Linear Fracture

Fracture runs parallel to the long axis of the bone.

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Oblique Fracture

Fracture occurs at an angle to the bone shaft.

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Spiral Fracture

Fracture spirals around the bone, due to rotational force.

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Transverse Fracture

Fracture runs straight across the bone at a 90-degree angle.

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Greenstick Fracture

One side of the bone is broken while the other side bends (like a green twig).

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Torus (Buckle) Fracture

Bone cortex buckles but does not break completely.

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Bowing Fracture

Longitudinal force causing one bone to bow while paired bone fractures.

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Pathologic Fracture

Occurs in bones weakened by disease, often with minimal trauma.

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Stress Fracture

Small cracks form due to repetitive stress, often without a single traumatic event.

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Fatigue Fracture

Caused by abnormal stress or torque applied repeatedly to a normal bone.

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Transchondral Fracture

Involves fragmentation and separation of a portion of articular cartilage.

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Primary (Direct) Bone Healing

Bone heals without callus formation, occurs when fracture ends are stabilized

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Secondary (Indirect) Bone Healing

Bone heals through callus formation, when there is some movement at the fracture site

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Hematoma Formation

A blood clot (hematoma) forms in the medullary canal and between fractured ends.

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Procallus Formation

Bone-forming cells in periosteum, endosteum, and marrow activate.

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Knee Dislocation

Various fractures; anterior, posterior, lateral,medial or rotary dislocation in the knee.

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Elbow Dislocation (Adults)

Trauma, often with an associated fracture of the ulna or radial head

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Pain Sign of Dislocation

Pain resulting from inflammatory exudates accumulating in joint.

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Joint Deformity

Joint deformity May be due to fluid buildup or muscle contractions.

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Limited range of motion

Caused by displacement of bones.

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Tendon

Fibrous connective tissue that attaches skeletal muscle to either bone or another structure.

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Ligament

A band of fibrous connective tissue that connects bones where they meet in a joint.

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Strain

Stretching or tearing of a muscle or tendon.

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Sprain

Tearing or stretching of a ligament.

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Proper Healing for tendon

If tendon remains stable, the attachment is strong.

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Substance P

A neuropeptide that enhances pain transmission and inflammation.

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Enkephalins

Enkephalins bind to 8 opioid receptors.

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Excitatory Neurotransmitters

Prostaglandins, histamine, and bradykinin contribute to sensitizing nociceptors.

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Gamma-Aminobutyric Acid (GABA)

Reduces pain transmission, major inhibitory neurotransmitter in the CNS.

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Nociceptors

Detect mechanical, thermal, or chemical stimuli.

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Aδ fibers

Large, myelinated fibers that transmit sharp, well-localized "fast" pain.

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Perceptual Dominance

Pain perception depends entirely on individual not stimulus alone.

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Acute Pain

Transient, lasting seconds to months, serving as a protective mechanism.

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Chronic Pain

Pain that lasts more than 3-6 months and serves no protective purpose.

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Referred Pain

Radiate to the left arm, may also be other areas.

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Pain Mechanisms

Ligaments of the spine have pain receptors.

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Degenerative Changes

Degenerative disk disease is a frequent cause of chronic LBP.

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Bone Mineral Density

Test only quantity of bones.

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Estrogen Deficiency

Decreases bone loss; accelerates menopause and causes bone resorption.

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OPG-Osteoprotegerin

Regulate bone formation.

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Osteosarcoma

Aggressive and destructive, long bones.

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Tumor

Bulky, extends in bone.

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Moth-eaten bone destruction

Tumors affect new bones.

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Chondroma

Infiltration.

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Fibrosarcoma

Fibrous tissue, Metaphysis of long bones.

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Giant Cell Tumor

Young Adults.

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Slow cortical erosion

Lies and attaches to the cortex.

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Ewing Sarcoma

Bones are more affected.

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Exogenous Osteomyelitis

Infection enters from outside the body.

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Endogenous Osteomyelitis

Pathogens travel via blood, common to infant, children.

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Joint Effusion

Inflammatory/synovial change.

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Study Notes

Fracture Types

  • Complete fractures involve a bone broken entirely into two or more separate pieces, potentially needing surgery or immobilization based on severity.
  • Incomplete fractures cause partial bone damage, are often due to bending or low impact, and are more common in children because their bones are more flexible; they usually heal well with immobilization.
  • Open (Compound) fractures occur with high-energy trauma which results in the bone breaking through the skin, which increases infection risk and typically requires surgical intervention.
  • Closed (Simple) fractures involve bone breaks that do not puncture the skin, often treated with casting or splinting, and are usually moderately difficult to treat.
  • Comminuted fractures result from severe trauma causing the bone to shatter into three or more pieces, a high difficulty injury often requiring surgery and hardware for fixation, and frequently occur in the elderly.
  • Linear fractures result from direct impact parallel to the bone axis which are often moderate in severity, and may heal with immobilization, more common in people of all ages.
  • Oblique fractures are a result of slanted force applied to the bone and often occur at an angle to the bone shaft which may need surgical fixation.
  • Spiral fractures are due to twisting force on the bone, often encircling it, and are difficult to treat due to misalignment, frequently requiring surgery, and more common in children and athletes.
  • Transverse fractures are caused by direct impact perpendicular to the bone, running straight across at a 90-degree angle and requires surgical stabilization to treat.
  • Greenstick fractures happen due to bending force on soft bones, breaking one side while bending the other with treatment involving use of a cast.
  • Torus (Buckle) fractures are due to compressive force causing buckling of the bone cortex without a complete break, a condition typically seen in children resolving with immobilization.

Other Fracture Considerations

  • Bowing Fracture: Longitudinal force is the cause, with one bone bending the other fracturing completely, more common in children.
  • Pathologic Fracture: Occurs secondary to disease weakening it and can lead to angular deformity, painless swelling, or generalized bone pain.
  • Stress Fracture: Repetitive strain from activity causes small cracks, more common in athletes, runners or any person doing repetitive physical activities.
  • Fatigue Fracture: Overuse leading to microfractures, and requires activity modification.
  • Transchondral Fracture: Repetitive microtrauma or sudden force that damages cartilage, and depending on where the injury is the treatment ranges from easy to difficult.

General Info on Fractures

  • Fractures of healthy bones, especially the tibia, clavicle, and lower humerus, usually occur in young people as a result of trauma.
  • Fractures of hand and foot bones are often caused by accidents in the workplace
  • Fractures of the upper femur, upper humerus, vertebrae, and pelvis occur more frequently in older adults and are often linked to osteoporosis.
  • Hip fractures, the most serious result of osteoporosis, exhibit significant geographical variations.
  • Stress fractures are painful due to increased remodeling; initially pain only occurs during activity and is usually relieved by rest and soft tissue swelling.
  • Transchondral fractures may be asymptomatic, or painful during movement.

Types of Bone Healing

  • Primary bone healing occurs when fracture ends are stabilized

  • Secondary bone healing occurs when there is movement at the fracture sites.

Primary Direct Bone Healing

  • Bone heals direct remodeling
  • Requires rigid stabilization like surgical fixation
  • has no callus formation
  • and is generally faster

Secondary Indirect Bone Healing

  • Bone goes through inflammatory, reparative and remodeling phases
  • Can use non-rigid fixation like casting
  • Involves callus formation
  • Takes longer to heal

Bone Healing Process Flowchart

  • Bones break, disrupting the periosteum, blood vessels, and surrounding soft tissues resulting in damaged bone ends that bleed into nearby soft tissue
  • A blood clot forms creating a hematoma in between fractured ends and beneath the periosteum
  • Dead tissue and debris trigger inflammation with vasodilation, plasma exudation, and infiltration of leukocytes.
  • New blood vessels from soft tissue and marrow invade the area increasing blood flow
  • Bone cells are activated and procallus forms along bone shaft and covers fractures
  • Subperiosteal procallus forms along the bone's outer surface.
  • The matrix mineralizes and hard callus forms as osteoblasts synthesize collagen and matrix in procallus.
  • The unnecessary callus is resorbed while creating new areas of stress.

Types of Joint Dislocations

  • Shoulder (Glenohumeral Joint) causes glenohumeral dislocation resulting from general trauma with the shoulder being the most dislocated joint in the body
  • Elbow (Radial Head), pulling on the hand or forearm the radial head can slip out, also known as "nursemaid's elbow"
  • Elbow dislocation can be traumatic with broken bones commonly occurring, and the ulna or radial head bones can get dislocated in the joint
  • Wrist, falling on a hyper extended hand causes dislocation of carpal bones
  • Hand dislocation occurs due to hyperextension, is common in contact sports
  • Hip are posterior from car accidents
  • Hip anterior occurs from forced abduction rare in healthy individuals from falling from high altitudes
  • Knee dislocations are unstable joints of various types such as anterior, posterior, medial, lateral, and rotary caused by hyperextension

Other disclocation information

  • Shoulder dislocations may damage the capsule and nerves
  • Nerve damage can disrupt the nerve sensory and paralyze deltoid muscle
  • Disrupting circulation can lead to ischemia and permanent disability
  • In hip can cause avascular necrosis of the femoral head

General Signs and Symptoms of Dislocation

  • Pain from inflammatory
  • Swelling due to joint deformity and muscle contractions
  • Limited range of motion and broken bones

Dislocations - Symptoms and Limitations

  • Shoulder dislocation happens with severe arm pain and limits its movement.
  • Elbow dislocation in kids limits pain at rest but hurts to move the arm
  • Adult Elbow dislocation also causes severe arm pain and resistance to movement, and can also cause joint deformity
  • Wrist dislocation causes lots of pain and inhibits bearing any weight
  • Painful finger dislocation
  • Car accidents causing pain and in the thigh or inguinal region causing immobility, resulting in the leg appearing shortened
  • Anterior hip has lots of pain and you cant move or rotate flexing the leg
  • Various knee dislocations also cause pain and immobility

General Information for Ligaments and Tendons

  • Tendons- muscles to bones enabling movement
  • Ligaments- connect bone to joint
  • Injuries to tendon or ligaments include sprains, strains and ruptures
  • Ligaments are in knee elbow and ankle for stability
  • Tendons are throughout body handling lots of movement like the achilles tendon

General Tendon Notes

  • Tendon is muscle to bone
  • Ligaments are bone to bone - Their difference is in function not structure
  • Sprains are ligament injury with stretching and tearing
  • wrist ankle elbow and knee commonly injured
  • Avulsion injuries separate soft tissues from attachment is sports
  • Strains are in tendons and ruptures with stretching and tearing
  • hands feet knee and arm are usually injured
  • Injuries can be due to heavy strain trauma
  • Also can be from arthritis, lupus or injections, antibiotics

Strains

  • First degree - fibers are stretched and functional with a stable joint
  • Second degree - partial tearing occurs with muscle contraction
  • Third degree - theres improper contraction because the muscle is completely torn

Healing

  • Torn area with bleeding
  • Formation with collagen in ligaments over 3-4 days
  • Muscle tissues align with collagen that interweaves
  • Collagen fibres attach and connect to the bones restoring joints
  • Injuries are also more susceptible to joint dislocations

Other joint injuries

  • commonly seen in finger and elbow sprains with the inability to function
  • the injuries limit mobility and cause lots of pain

The step by step for pain transmission

  • Noxious stimulus activates pain receptors that convert to electrical signals
  • these receptors cause a response using stimuli
  • signals travel through spinal cord to neurons through brain using Ad fibers with well localized fast pain
  • slow transmissions are through unmyelinated C fibers which transmit slow pain
  • Spinothalamic tracts carry this signal through brain which sends signals to cerebral cortex to control the location of pain
  • pain is understood with 3 systems
  • sensoring which uses the somatosensory cortex to identify
  • affective- motivational is limbic feeling and the brainstem
  • cognitive is modified experience which modify thoughts
  • all of this information gets enhanced and suppressed as well and transmitted using enkephalins, endorphins

Role for pain modulation

  • The body regulates pain using signals that is regulated using a pain threshold with neuromodulator which gets raised using certain actions like exercising and such
  • Different methods of inhibitory for the body is to increase and decrease pain by releasing chemicals like prostaglandins histamines

Pain Modulations

  • Are by means of chemical modulators like releasing chemicals that increase pain
  • Other factors like endorphins also affect this

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