Blood Tissue Overview
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Questions and Answers

Which of the following cells are primarily involved in humoral immunity?

  • T-lymphocytes
  • Monocytes
  • B-lymphocytes (correct)
  • Eosinophils
  • Eosinophils increase in number during measles and typhus infections.

    False (B)

    What is the shape of a monocyte's nucleus?

    Kidney-shaped

    The number of platelets in a healthy individual typically ranges from ________ to 40 x 10⁹/l.

    <p>20</p> Signup and view all the answers

    Which of the following statements regarding thrombocytopenia is accurate?

    <p>It is characterized by a decreased number of platelets. (A)</p> Signup and view all the answers

    Match the blood components with their descriptions:

    <p>Eosinophils = Increase in allergic reactions and parasitic infections Platelets = Involved in blood clotting Monocytes = Form macrophages in connective tissue B-lymphocytes = Synthesize antibodies for humoral immunity</p> Signup and view all the answers

    Lymphocytes can be categorized into small, medium, and large based on their dimensions.

    <p>True (A)</p> Signup and view all the answers

    The molecules synthesized by activated B-lymphocytes are called ________.

    <p>antibodies</p> Signup and view all the answers

    Which type of leukocyte is most abundant in a complete blood count (CBC)?

    <p>Neutrophils (D)</p> Signup and view all the answers

    Eosinophils are classified as microphages.

    <p>False (B)</p> Signup and view all the answers

    What are the three key functions of basophils?

    <p>Modulate inflammatory processes, release histamine during allergy, and act as anticoagulants.</p> Signup and view all the answers

    Neutrophils primarily function as __________, engulfing and destroying bacteria.

    <p>phagocytes</p> Signup and view all the answers

    Match the following types of leukocytes with their characteristics:

    <p>Neutrophils = Increased during bacterial infections Basophils = Release of histamine and modulate inflammation Eosinophils = Combat parasites and allergic reactions Monocytes = Differentiate into macrophages in tissues</p> Signup and view all the answers

    What percent of leukocytes in a normal CBC is represented by eosinophils?

    <p>1 - 4% (C)</p> Signup and view all the answers

    Histamine secreted by basophils reduces capillary permeability.

    <p>False (B)</p> Signup and view all the answers

    What is neutrophilia?

    <p>An increased number of neutrophils in a CBC.</p> Signup and view all the answers

    What is the primary fluid component of blood?

    <p>Blood plasma (D)</p> Signup and view all the answers

    Erythrocytes are also known as white blood cells.

    <p>False (B)</p> Signup and view all the answers

    What is the lifespan of erythrocytes in women?

    <p>110 days</p> Signup and view all the answers

    The process of blood clotting involves platelets and _____ proteins.

    <p>plasma</p> Signup and view all the answers

    Match the following blood components with their primary functions:

    <p>Erythrocytes = Transport of O2 and CO2 Leukocytes = Immune defense Thrombocytes = Blood clotting Plasma = Transport nutrients and waste</p> Signup and view all the answers

    Which of the following is a function of leukocytes?

    <p>Immune defense (A)</p> Signup and view all the answers

    The average erythrocyte count for men is lower than for women.

    <p>False (B)</p> Signup and view all the answers

    What is the embryonic origin of blood tissue?

    <p>Mesenchyme</p> Signup and view all the answers

    The number of erythrocytes can increase to a condition known as _____ when there is an elevated count.

    <p>erythrocytosis</p> Signup and view all the answers

    Which component of blood has a biconcave disk shape and is anucleate?

    <p>Erythrocytes (B)</p> Signup and view all the answers

    Flashcards

    Eosinophil increase

    An increase in eosinophil count in the blood, often associated with allergic reactions and parasitic infections.

    Eosinopenia

    A decrease in eosinophil count in the blood, often seen with certain illnesses like measles and typhus or immunosuppressive treatments.

    Lymphocyte size

    Lymphocytes are categorized by size: small (6-8µm), medium (8-12µm), and large (12-18µm).

    Lymphocyte nucleus

    Lymphocyte nuclei are eccentric (not centrally located) and have heterochromatin arranged radially, like 'wheel spokes'.

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    B-lymphocytes

    B-lymphocytes produce antibodies and are involved in humoral immunity.

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    T-helper cells

    T-helper cells regulate the immune response.

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    Monocytes' function

    Monocytes differentiate into macrophages, which perform phagocytosis (engulfing) of pathogens and present antigens.

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    Platelets function

    Platelets are crucial for blood clotting.

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    Blood Function

    Blood transports nutrients, oxygen, and waste products; defends against infection; and regulates body temperature.

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    Blood Components

    Blood consists of blood cells (erythrocytes, leukocytes, thrombocytes) and plasma.

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    Erythrocytes

    Red blood cells; carry oxygen and carbon dioxide.

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    Leukocytes

    White blood cells; part of the immune system.

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    Thrombocytes

    Blood platelets; essential for blood clotting.

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    Blood Plasma

    The liquid part of blood; transports nutrients, waste, and blood cells.

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    Hemoglobin

    The protein in red blood cells that carries oxygen.

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    Erythrocyte Count (Normal)

    The range of normal red blood cell counts for males and females.

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    Erythroclasis

    Breakdown of old red blood cells in the spleen and liver.

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    Blood Tissue Location

    Blood is found in blood vessels and hematopoietic organs.

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    Neutrophils

    A type of white blood cell (leukocyte) with a multi-lobed nucleus and granules that help fight infection.

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    Neutrophil Granules

    Neutrophils contain both specific and non-specific granules. Specific granules contain antibacterial substances; non-specific granules are lysosomes (containing enzymes).

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    Basophils Function

    Basophils release histamine and heparin which activate inflammatory processes and prevent blood clotting.

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    Basophils

    Another type of white blood cell with irregular shaped nucleus and granules that stain basophilic; they are involved in allergies and inflammatory responses.

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    Eosinophils

    A type of white blood cell with a bi-lobed nucleus, and granules that stain strongly pink-orange. They are important for fighting parasites and certain allergic reactions.

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    Eosinophil Granules

    Eosinophil granules contain substances like antihistamines, which help counter allergic reactions.

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    Microphages

    These are cells involved in phagocytosis, the process of engulfing and destroying foreign particles or pathogens.

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    Neutrophilia

    An increased number of neutrophils in blood, often indicative of infection.

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    Study Notes

    Blood Tissue

    • Blood is a fundamental tissue type
    • Accounts for 7% - 8% of total body weight
    • Ranges from 4 to 6 liters
    • Composed of two key components: cells and plasma (fluid extracellular component)

    Blood Cells

    • Erythrocytes (red blood cells): These cells carry oxygen
    • Leukocytes (white blood cells): Crucial for the immune system
    • Thrombocytes (platelets): Involved in blood clotting

    Fluid Extracellular Component

    • Blood plasma: This component makes up approximately 55% of blood

    Blood Tissue - Localization

    • Blood vessels
    • Hematopoietic organs

    Blood Tissue - Functions: Metabolism

    • Water-salt exchange
    • Nutrient and metabolic product transport

    Blood Tissue - Functions: Respiratory

    • Oxygen (O2) and carbon dioxide (CO2) transport between alveoli and tissue cells (primarily erythrocyte function)

    Blood Tissue - Functions: Protective

    • White blood cells (leukocytes) participate in immune responses

    Blood Tissue - Functions: Regulatory

    • Transport of hormones, growth factors, and other active substances
    • Thermoregulation
    • Blood clotting (formation of thrombi in vessel ruptures - platelet and plasma protein function)

    Blood Tissue - Embryonic Origin

    • Mesenchyme (fourth embryonic layer)

    Erythrocytes

    • Red blood cells (RBC)
    • Functional role: respiratory function (oxygen and carbon dioxide transport)
    • Typical shape: biconcave disc (7-8 µm)
    • Lack a nucleus (anucleate cells)
    • Cytoplasm is filled with hemoglobin
    • Normal count: Men – 4.5 to 5.8 x 1012/L, Women – 4.2 to 5.4 x 1012/L
    • Lifespan: in men – 140 days, in women – 110 days
    • Breakdown is called erythroclasis (takes place in the liver and spleen)
    • Increased RBC count: erythrocytosis
    • Decreased RBC count: erythropenia

    Hemoglobin

    • Complex protein
    • Composed of four polypeptide chains of globin
    • Each globin chain contains a heme molecule containing iron (iron binds reversibly with oxygen or carbon dioxide).

    Leukocytes

    • White blood cells (WBC), leukocytes
    • Circulate in blood, but function outside of blood vessels
    • Move through capillary walls using pseudopodia (diapedesis)
    • Normal count: 4 - 10 x 109/L
    • Increased white blood cell count: leukocytosis
    • Decreased white blood cell count: leukopenia

    Types of Leukocytes

    • Granulocytes (with specific granules)
      • Neutrophils (Neu): 55-65% in CBC; 12-15µm; multiple lobes; phagocytosis of bacteria
      • Eosinophils (Eo): 1-4% in CBC; 17µm, two-lobed nucleus; response to allergic reactions
      • Basophils (Ba): 0.5-1% in CBC, irregular nucleus, release histamine
    • Agranulocytes (without specific granules)
      • Lymphocytes (Ly): 25-35% in CBC; various sizes (6-8µm, 8-12µm, 12-18µm); involved in immune response
      • Monocytes (Mo): 4-8% in CBC; 20µm; kidney-shaped nucleus; differentiation into macrophages

    Complete Blood Count (CBC)

    • Measures percentages of leukocytes in blood
    • Reveals unusual increases or decreases in cell counts, which may indicate underlying medical conditions
    • Used to monitor treatment

    Platelets (Thrombocytes)

    • Cytoplasmic fragments of megakaryocytes
    • Crucial for blood clotting
    • Normal platelet count: 20–40 × 109/L
    • Increased platelet count: thrombocytosis
    • Decreased platelet count: thrombocytopenia
    • Contain granules with clotting factors, serotonin, other substances for platelet aggregation, and lysosomes

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    Blood Tissue PDF

    Description

    Explore the fundamental aspects of blood tissue, including its composition, function, and localization in the body. This quiz covers the types of blood cells, their roles in transport and protection, and the significance of plasma. Test your knowledge and deepen your understanding of this essential body tissue.

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