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Questions and Answers
What is poikilocytosis characterized by?
What is poikilocytosis characterized by?
- A decrease in the production of platelets
- Variation in size of red blood cells (correct)
- An increase in the number of blood cells
- Lack of variation in the shape of red blood cells
Which condition is caused by a deficiency in folate?
Which condition is caused by a deficiency in folate?
- Meganoblastic anemia (correct)
- Sickle cell anemia
- Iron-deficiency anemia
- Hemolytic anemia
What is the primary role of megakaryocytes in the bone marrow?
What is the primary role of megakaryocytes in the bone marrow?
- Creation of lymphocytes
- Formation of platelets (correct)
- Production of red blood cells
- Development of granulocytes
What does hypochromic mean in a blood test?
What does hypochromic mean in a blood test?
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Anisocytosis refers to what feature of red blood cells?
Anisocytosis refers to what feature of red blood cells?
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What kind of anemia is characterized by a central zone that is large and pale in red blood cells?
What kind of anemia is characterized by a central zone that is large and pale in red blood cells?
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Which of the following is a hallmark feature of neutrophils in the bone marrow?
Which of the following is a hallmark feature of neutrophils in the bone marrow?
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What causes the symptoms of pallor in anemic conditions?
What causes the symptoms of pallor in anemic conditions?
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Study Notes
Bone Marrow (BM) and Blood Elements
- Bone marrow produces key blood components, including granulocytes, erythrocytes, and platelets.
- Amegakaryocytes are essential for platelet production.
- Neutrophils in the blood respond to infection and inflammation, characterized by segmented nuclei.
Blood Cell Characteristics
- Poikilocytosis refers to variation in red blood cell (RBC) shape.
- Anisocytosis indicates variation in red blood cell size, often seen in anemic conditions.
- Hypochromic anemia presents as pale-colored RBCs due to insufficient hemoglobin.
Anemia Types and Causes
- Megaloblastic anemia is linked to vitamin B12 or folate deficiency, affecting red blood cell maturation.
- Pernicious anemia is another type stemming from a deficiency in intrinsic factor, leading to impaired vitamin B12 absorption.
- Symptoms of anemia may include pallor and fatigue, highlighting the body's reduced oxygen-carrying capacity.
Red Blood Cell and Platelet Features
- Central pallor in RBCs may indicate hypochromia.
- Megaloblastic anemia may exhibit large, abnormal RBCs termed macrocytes.
- Effective bone marrow function relies on the integration of various precursor cells to maintain homeostasis in blood cell production.
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