Lecture 1.2b - Fundamentals of blood pressure - Hemodynamics
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Questions and Answers

What determines the direction of blood flow in the circulatory system?

  • Cardiac output
  • Pressure gradient (correct)
  • Stroke volume
  • Total peripheral resistance
  • What is the relationship between flow rate and cardiac output?

  • Flow rate is equal to cardiac output
  • Flow rate is directly proportional to cardiac output (correct)
  • Flow rate is inversely proportional to cardiac output
  • Flow rate is independent of cardiac output
  • In which part of the circulatory system is the pressure drop the greatest?

  • Arteries
  • Arterioles (correct)
  • Venules
  • Capillaries
  • What is the relationship between velocity and area of blood vessels?

    <p>Velocity is inversely proportional to area</p> Signup and view all the answers

    What is the unit of measurement for cardiac output?

    <p>ml/minute</p> Signup and view all the answers

    What is the formula for blood pressure?

    <p>Pressure difference = CO x TPR</p> Signup and view all the answers

    What is the formula for calculating resistance in the vascular system?

    <p>Resistance = pressure difference/CO</p> Signup and view all the answers

    Which of the following conditions would increase viscosity in the vascular system?

    <p>Polycythemia</p> Signup and view all the answers

    What is the main reason why capillaries have low resistance?

    <p>They are arranged in parallel with each other</p> Signup and view all the answers

    Which type of flow is characterized by being smooth and in a straight line?

    <p>Laminar flow</p> Signup and view all the answers

    What is the formula for calculating mean arterial pressure (MAP)?

    <p>2/3 DBP + 1/3 SBP</p> Signup and view all the answers

    What is the primary function of the pulse?

    <p>To indicate heart rate</p> Signup and view all the answers

    What is the main factor that affects resistance in arterioles?

    <p>Radius of the vessel</p> Signup and view all the answers

    What is the unit of measurement for blood pressure?

    <p>mmHg</p> Signup and view all the answers

    Study Notes

    Blood Flow

    • Blood flow is driven by a pressure gradient, with a major pressure drop in arteries leading to a drop in pressure by the time the blood reaches the capillaries.
    • Low pressure is present in the venule system.
    • Flow is directly proportional to the change in pressure and inversely proportional to resistance.
    • Blood flows from high to low pressure.

    Blood Pressure

    • Blood pressure is determined by the pressure difference, which is the product of cardiac output (CO) and total peripheral resistance (TPR).
    • CO is the total volume of blood pumped out of the ventricles per minute, calculated by heart rate x stroke volume.
    • Stroke volume is the total volume of blood in ml pumped out of the ventricles for every 1 beat, approximately 4900ml or 5L/minute.
    • Cardiac output is the total volume of blood pumped out of the ventricles per minute.

    Cardiac Output, Flow, Velocity, and Area

    • Cardiac output is measured in ml/minute.
    • Flow rate is equal to cm3/minute or ml/minute.
    • Velocity is measured in cm/min or calculated as Flow/area.
    • Velocity is directly proportional to flow and inversely proportional to area.
    • When the area of the capillaries is high, the velocity of blood travelling through them is low.

    Resistance

    • Resistance is calculated by dividing pressure difference by CO or flow.
    • Poiseuille's equation is used to calculate resistance, which is influenced by viscosity, length, and radius of the vessel.
    • Viscosity is increased in polycythemia and dehydration, and decreased in anemia.
    • Length of the vessel is increased with weight and height.
    • Radius of the vessel is increased in vasodilation and decreased in vasoconstriction.

    Resistance in Series and Parallel Vascular Circuits

    • Normal blood pressure is 120/80 mmHg.
    • Series and parallel circuits are needed to maintain blood pressure.
    • Capillaries have low resistance due to their parallel arrangement.
    • Arterioles have the highest resistance due to their ability to change diameter through vasodilation and vasoconstriction.

    Types of Flow

    • Laminar flow is smooth, silent, and has low resistance.
    • Turbulent flow is chaotic, noisy, and has high resistance.
    • Differences in flow properties allow for blood pressure management.

    Blood Pressure

    • Pressure is calculated as force/unit area.
    • Blood pressure is the force exerted by blood on the vessels.
    • Systolic blood pressure (SBP) is the pressure in arteries during systole, approximately 120 mmHg.
    • Diastolic blood pressure (DBP) is the pressure in arteries during diastole, approximately 80 mmHg.
    • Pulse pressure (PP) is the difference between SBP and DBP, approximately 40 mmHg.
    • Mean arterial pressure (MAP) is calculated as 2/3 DBP + 1/3 SBP, approximately 93.3 mmHg.

    Pulse

    • Pulse is created by the expansion and recoiling of arteries.
    • Pulse indicates heart rate.
    • Pulse is most readily measured at the radial artery.
    • Pulse is recorded as beats per minute.
    • Both the rate and strength of the pulse are important clinically.

    Blood Pressure Measurement

    • Blood pressure is measured in mmHg.

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    Description

    This quiz covers the principles of blood flow, including the role of pressure gradients, resistance, and vessel diameter. Learn how blood pressure changes throughout the circulatory system.

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