Blood Flow and Cardiac Function

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Questions and Answers

A patient's blood pressure is chronically elevated due to increased peripheral resistance. Which of the following interventions would directly address this cause?

  • Recommending a diet high in sodium to increase fluid retention.
  • Administering a diuretic to reduce blood volume.
  • Prescribing a medication that increases heart rate and contractility.
  • Administering a vasodilator to decrease vessel constriction. (correct)

During a marathon, a runner's blood flow to the skeletal muscles increases significantly. Which local metabolic change contributes most directly to this vasodilation?

  • Increased oxygen concentration.
  • Increased pH (more alkaline).
  • Increased carbon dioxide levels. (correct)
  • Decreased carbon dioxide levels.

The sympathetic nervous system influences blood pressure by causing:

  • Decreased heart rate and vasodilation.
  • Increased heart rate and vasoconstriction. (correct)
  • Increased heart rate and vasodilation.
  • Decreased heart rate and vasoconstriction.

Which type of blood vessel is primarily responsible for regulating blood flow into capillary beds?

<p>Arterioles (A)</p> Signup and view all the answers

What compensatory mechanism occurs in response to a sudden drop in blood pressure?

<p>Activation of the renin-angiotensin-aldosterone system (RAAS). (B)</p> Signup and view all the answers

Which of the following factors would increase blood flow to a tissue?

<p>Increased pressure gradient. (A)</p> Signup and view all the answers

How do veins counteract the effects of gravity to ensure blood returns to the heart?

<p>Valves that prevent backflow of blood. (A)</p> Signup and view all the answers

Which of the following best illustrates the role of capillaries in maintaining tissue homeostasis?

<p>Exchanging nutrients and waste products between blood and tissues. (A)</p> Signup and view all the answers

What is the primary long-term mechanism for regulating blood pressure?

<p>Control of blood volume by the kidneys. (B)</p> Signup and view all the answers

A person experiences a sudden increase in blood pressure. What immediate response would the body initiate to lower it?

<p>Increased parasympathetic nervous system activity. (A)</p> Signup and view all the answers

How does nitric oxide (NO) typically affect blood vessels?

<p>It causes vasodilation leading to decreased blood pressure. (A)</p> Signup and view all the answers

The length of a blood vessel increases due to a patient gaining weight. How does this affect blood flow, assuming other factors remain constant?

<p>Blood flow decreases proportionally. (D)</p> Signup and view all the answers

During exercise, the heart's contractility increases due to sympathetic stimulation. Which receptor type mediates this effect in the heart?

<p>Beta-adrenergic receptors. (D)</p> Signup and view all the answers

What effect does increased activity of the parasympathetic nervous system have on the heart?

<p>Decreases heart rate and contractility. (D)</p> Signup and view all the answers

What happens to blood pressure if cardiac output increases while peripheral resistance remains constant?

<p>Blood pressure increases. (D)</p> Signup and view all the answers

Epinephrine can bind to both alpha and beta adrenergic receptors. Which of the following effects is primarily mediated by alpha-adrenergic receptor activation?

<p>Vasoconstriction in peripheral blood vessels. (B)</p> Signup and view all the answers

A patient with kidney disease has impaired long-term blood pressure regulation. Which of the following mechanisms is most likely affected?

<p>Control of blood volume. (B)</p> Signup and view all the answers

If the radius of a blood vessel decreases by half due to vasoconstriction, how would this affect the resistance to blood flow, assuming all other factors remain constant?

<p>Resistance increases to sixteen times its original value. (B)</p> Signup and view all the answers

Which of the following conditions would typically result in vasodilation?

<p>Increased local concentration of carbon dioxide. (A)</p> Signup and view all the answers

Flashcards

Cardiac Function

The heart's ability to pump blood effectively to meet the body's needs.

Cardiac output, stroke volume, and heart rate

Determines how well the heart functions.

Mechanics of Blood Flow

Blood flow depends on pressure gradients and vascular resistance.

Peripheral Resistance

Affected by blood viscosity, vessel length, and vessel radius.

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Blood Flow Direction

Blood flows from areas of higher pressure to areas of lower pressure.

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Regulation of Blood Pressure

Short-term regulation via the nervous system and hormones; long-term regulation through the kidneys.

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Sympathetic Nervous System

Increases heart rate, contractility, and vasoconstriction, raising blood pressure.

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Parasympathetic Nervous System

Decreases heart rate and contractility, lowering blood pressure.

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Renin-Angiotensin-Aldosterone System (RAAS)

Regulates blood volume and vascular resistance.

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Arteries

Carry blood away from the heart; thick-walled and elastic.

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Arterioles

Control blood flow into capillaries through vasoconstriction and vasodilation.

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Capillaries

Thin-walled vessels that facilitate the exchange of substances between blood and tissues.

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Veins

Carry blood back to the heart; have valves to prevent backflow; more compliant than arteries.

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Intrinsic Factors

Local metabolic factors like oxygen, carbon dioxide, pH, and nitric oxide affecting vasodilation and vasoconstriction.

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Extrinsic Factors

Sympathetic/parasympathetic nervous systems and hormones like epinephrine and angiotensin II systemically regulate blood flow and pressure.

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Sympathetic Activation

Generally causes vasoconstriction through alpha-adrenergic receptors, increasing blood pressure.

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Parasympathetic Activation

Has minimal direct effect on most blood vessels but can cause vasodilation in certain tissues via nitric oxide.

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Heart's Response to Sympathetic Stimulation

Increases rate and force of contraction via beta-adrenergic receptors.

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Parasympathetic Stimulation

Slows the heart rate through the vagus nerve.

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Study Notes

  • Transports nutrients, oxygen, hormones, and immune cells to cells in the body
  • Removes metabolic waste products

Cardiac Function

  • Refers to the heart's ability to pump blood effectively to meet the body's needs
  • Cardiac output, stroke volume, and heart rate determine how well the heart functions
  • Blood vessels transport blood throughout the body facilitating the exchange of oxygen, nutrients and waste products between blood and tissues
  • Blood flow is influenced by blood pressure, resistance in blood vessels, and the heart's pumping action
  • Blood pressure is vital for circulating blood and is affected by cardiac output, blood volume, and vascular resistance
  • Sympathetic and parasympathetic nervous systems, hormones, and local factors regulate blood pressure

Mechanics of Blood Flow

  • Blood flow depends on pressure gradients and vascular resistance
  • Peripheral resistance is affected by blood viscosity, vessel length, and vessel radius
  • Blood flows from high to low pressure areas
  • Blood flow is directly proportional to the pressure gradient but inversely proportional to resistance
  • Vasoconstriction decreases blood flow, while vasodilation increases blood flow

Regulation of Blood Pressure

  • Short-term regulation via the nervous system and hormones
  • Long-term regulation through the kidneys, which control blood volume
  • The sympathetic nervous system increases heart rate, contractility, and vasoconstriction, raising blood pressure
  • The parasympathetic nervous system decreases heart rate and contractility, lowering blood pressure
  • The renin-angiotensin-aldosterone system (RAAS) regulates blood volume and vascular resistance

Types of Vessels

  • Arteries carry blood away from the heart and are thick-walled, and elastic
  • Arterioles control blood flow into capillaries through vasoconstriction and vasodilation
  • Capillaries are thin-walled vessels that facilitate the exchange of substances between blood and tissues
  • Veins carry blood back to the heart, have valves to prevent backflow, and are more compliant than arteries
  • Venules collect blood from capillaries and merge into veins

Intrinsic and Extrinsic Factors

  • Intrinsic factors include local metabolic factors like oxygen, carbon dioxide, pH, and nitric oxide, which affect vasodilation and vasoconstriction
  • Extrinsic factors include the sympathetic and parasympathetic nervous systems, hormones (epinephrine, angiotensin II), which systemically regulate blood flow and pressure
  • Sympathetic activation generally causes vasoconstriction through alpha-adrenergic receptors, increasing blood pressure
  • Parasympathetic activation has minimal direct effect on most blood vessels but can cause vasodilation in certain tissues via nitric oxide
  • The heart responds to sympathetic stimulation with increased rate and force of contraction via beta-adrenergic receptors
  • Parasympathetic stimulation slows the heart rate through the vagus nerve

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