Blood Donation: Health History Questionnaire and Physical Examination

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What is the purpose of the health history questionnaire given to blood donors?

To protect the health of both the donor and the recipient (correct)

To identify donors with low hemoglobin levels

To confirm the donor's genetic background

To check the donor's blood type compatibility

Which diseases are mentioned as examples that can be transmitted through blood in the questionnaire?

Diabetes and hypertension

Cancer and Alzheimer's

West Nile virus and malaria (correct)

Influenza and common cold

What is the goal of blood preservation?

To increase the incidence of skin lesions in donors

To decrease blood pressure in donors

To reduce the number of blood donors needed

To maintain viable blood components for transfusion (correct)

What is the expected post-transfusion RBC survival after 24 hours, according to the text?

75% Signup and view all the answers

Where is blood containing RBCs stored to maintain optimum viability?

Between 1°C to 6°C Signup and view all the answers

What has been correlated with the loss of RBC viability?

Storage duration and associated biochemical changes Signup and view all the answers

Who was the first person to record a blood transfusion in history?

Pope Innocent VII Signup and view all the answers

What did Samuel Pepys speculate about blood transfusion in 1666?

That 'bad blood' could be mended by borrowing blood from a healthier body Signup and view all the answers

What was the purpose of Blundell's 'Impellor'?

To perform a controlled blood transfusion Signup and view all the answers

Who came up with a design for performing blood transfusion involving silver cannulae and rubber tubing with a bulb in the middle?

Edward Lindemann Signup and view all the answers

What animal-to-human transfusion attempt occurred on June 15, 1667?

Sheep to human Signup and view all the answers

Who conducted the first photograph-documented blood transfusion at Bellevue Hospital in 1876?

James Aveling Signup and view all the answers

What was the first anticoagulant recommended by Braxton Hicks in 1869?

Sodium phosphate Signup and view all the answers

Who discovered the ABO blood group in 1901?

Karl Landsteiner Signup and view all the answers

In what year did John Loutit and Patrick Mollison introduce the formula for the preservative ACD?

1957 Signup and view all the answers

What is the maximum volume of blood that can be collected from a 110-lb donor according to AABB standards?

525 mL Signup and view all the answers

How often can a person donate blood according to AABB guidelines?

Every 2 months Signup and view all the answers

How quickly does the body recover the blood plasma volume after donation?

Within 24-48 hours Signup and view all the answers

What is a cryoprotective agent used in the rejuvenation process?

Glycerol Signup and view all the answers

Which freezing temperature is typically used for rejuvenating RBCs?

-80°C Signup and view all the answers

What is a key advantage of the High Glycerol Concentration Technique over the Low Glycerol Concentration Technique?

Can be thawed and refrozen Signup and view all the answers

When are RBCs stored in the liquid state typically rejuvenated?

At outdate Signup and view all the answers

What is one disadvantage of using Rejuvesol in the rejuvenation process?

Expensive and time-consuming Signup and view all the answers

What is the purpose of washing RBCs during the post-freezing deglycerolization process?

To remove nonmetabolized rejuvenation solution materials Signup and view all the answers

What is the main role of citrate in anticoagulant preservative solutions?

Binding to calcium to prevent blood clotting Signup and view all the answers

Which anticoagulant preservative solution extends the shelf life of red blood cells from 21 to 35 days by adding adenine?

CPDA-1 Signup and view all the answers

What is the function of additive solutions in RBC storage?

Extend the shelf life of RBCs by adding nutrients Signup and view all the answers

Which additive solution contains SAGM to retard hemolysis?

ADsol (AS-1) Signup and view all the answers

What is the primary role of adenine in anticoagulant preservative solutions?

Driving glycolysis to produce ATP Signup and view all the answers

Which anticoagulant preservative solution has the highest glucose content for lengthening the storage of blood?

CP2D Signup and view all the answers

Why are additive solutions added to RBCs after removing plasma?

To maintain adequate nutrient levels during storage Signup and view all the answers

What does the initial rejuvenation solution contain mainly for restoring ATP and 2,3-DPG levels?

(PHIGPA) Phosphate, Inosine, Glucose, Pyruvate, Adenine Signup and view all the answers

'Autologous transfusion' primarily involves individuals donating blood for:

'Autologous' use in meeting their own needs for blood transfusion Signup and view all the answers