33 Questions
What is the purpose of the health history questionnaire given to blood donors?
To protect the health of both the donor and the recipient
Which diseases are mentioned as examples that can be transmitted through blood in the questionnaire?
West Nile virus and malaria
What is the goal of blood preservation?
To maintain viable blood components for transfusion
What is the expected post-transfusion RBC survival after 24 hours, according to the text?
75%
Where is blood containing RBCs stored to maintain optimum viability?
Between 1°C to 6°C
What has been correlated with the loss of RBC viability?
Storage duration and associated biochemical changes
Who was the first person to record a blood transfusion in history?
Pope Innocent VII
What did Samuel Pepys speculate about blood transfusion in 1666?
That 'bad blood' could be mended by borrowing blood from a healthier body
What was the purpose of Blundell's 'Impellor'?
To perform a controlled blood transfusion
Who came up with a design for performing blood transfusion involving silver cannulae and rubber tubing with a bulb in the middle?
Edward Lindemann
What animal-to-human transfusion attempt occurred on June 15, 1667?
Sheep to human
Who conducted the first photograph-documented blood transfusion at Bellevue Hospital in 1876?
James Aveling
What was the first anticoagulant recommended by Braxton Hicks in 1869?
Sodium phosphate
Who discovered the ABO blood group in 1901?
Karl Landsteiner
In what year did John Loutit and Patrick Mollison introduce the formula for the preservative ACD?
1957
What is the maximum volume of blood that can be collected from a 110-lb donor according to AABB standards?
525 mL
How often can a person donate blood according to AABB guidelines?
Every 2 months
How quickly does the body recover the blood plasma volume after donation?
Within 24-48 hours
What is a cryoprotective agent used in the rejuvenation process?
Glycerol
Which freezing temperature is typically used for rejuvenating RBCs?
-80°C
What is a key advantage of the High Glycerol Concentration Technique over the Low Glycerol Concentration Technique?
Can be thawed and refrozen
When are RBCs stored in the liquid state typically rejuvenated?
At outdate
What is one disadvantage of using Rejuvesol in the rejuvenation process?
Expensive and time-consuming
What is the purpose of washing RBCs during the post-freezing deglycerolization process?
To remove nonmetabolized rejuvenation solution materials
What is the main role of citrate in anticoagulant preservative solutions?
Binding to calcium to prevent blood clotting
Which anticoagulant preservative solution extends the shelf life of red blood cells from 21 to 35 days by adding adenine?
CPDA-1
What is the function of additive solutions in RBC storage?
Extend the shelf life of RBCs by adding nutrients
Which additive solution contains SAGM to retard hemolysis?
ADsol (AS-1)
What is the primary role of adenine in anticoagulant preservative solutions?
Driving glycolysis to produce ATP
Which anticoagulant preservative solution has the highest glucose content for lengthening the storage of blood?
CP2D
Why are additive solutions added to RBCs after removing plasma?
To maintain adequate nutrient levels during storage
What does the initial rejuvenation solution contain mainly for restoring ATP and 2,3-DPG levels?
(PHIGPA) Phosphate, Inosine, Glucose, Pyruvate, Adenine
'Autologous transfusion' primarily involves individuals donating blood for:
'Autologous' use in meeting their own needs for blood transfusion
Learn about the importance of a uniform donor health history questionnaire and an abbreviated physical examination in blood donation process. Understand how these measures help protect the health of both the donor and the recipient.
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