Blood Composition and Functions

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Questions and Answers

A patient has an abnormally high count of eosinophils in their blood work. Which condition is MOST likely causing this elevated level?

  • Iron deficiency
  • Parasitic infection (correct)
  • Viral infection
  • Bacterial infection

Red blood cells, also known as erythrocytes, contain a nucleus to facilitate oxygen transport.

False (B)

What is the primary function of hemoglobin within red blood cells?

oxygen transport

A blood sample that is bright red in color indicates that the blood is ______.

<p>oxygenated</p> Signup and view all the answers

Match the following white blood cells with their primary functions:

<p>Neutrophils = Phagocytosis and destruction of bacteria and fungi Lymphocytes = Kill viruses; Make antibodies Basophils = Inflammatory response Monocytes = Remove dead cells; Differentiate into macrophages</p> Signup and view all the answers

Which of the following is NOT a typical function associated with blood?

<p>Production of digestive enzymes (D)</p> Signup and view all the answers

Individuals with Rh-positive blood possess Rh antibodies in their plasma.

<p>False (B)</p> Signup and view all the answers

What is the approximate lifespan of platelets in the human circulatory system?

<p>5-9 days</p> Signup and view all the answers

The percentage of blood volume composed of formed elements, such as red blood cells, white blood cells, and platelets, is approximately ______%.

<p>45</p> Signup and view all the answers

After centrifuging a sample of blood, you observe that the buffy coat, containing white blood cells and platelets, is significantly thicker than normal. What does this likely indicate?

<p>Infection or inflammation (C)</p> Signup and view all the answers

Flashcards

What is Blood?

Liquid connective tissue that transports substances, regulates pH and temperature, and protects against blood loss and disease.

What is Blood Plasma?

The liquid extracellular matrix of blood, containing proteins, water, and other solutes.

What are Formed Elements?

Cellular components of blood, including red blood cells, white blood cells, and platelets.

What are Erythrocytes?

Red blood cells, specialized for oxygen transport due to the presence of hemoglobin. They are biconcave discs without a nucleus.

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What is Hemoglobin?

Proteins in red blood cells responsible for carrying oxygen and nutrients.

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What are Leukocytes?

White blood cells, involved in immune responses; classified as granular (neutrophils, eosinophils, basophils) and agranular (lymphocytes, monocytes).

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What are Neutrophils?

Granular leukocytes that phagocytize and destroy bacteria and fungi.

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What are Lymphocytes?

Agranular leukocytes that kill viruses and produce antibodies.

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What are Platelets (Thrombocytes)?

Cell fragments that promote blood clotting.

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What are Blood Types?

Blood classification based on the presence or absence of specific antigens (glycoproteins and glycolipids) on the surface of red blood cells.

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Study Notes

  • Blood is liquid connective tissue with cells in a liquid extracellular matrix.
  • Key functions include transportation, regulation, and protection.

Blood Characteristics

  • More dense and viscous than water.
  • Temperature is 38 degrees Celsius (100.4 Fahrenheit).
  • Has an alkaline pH, ranging from 7.35 to 7.45.
  • Oxygenated blood is bright red, while deoxygenated blood is dark red.
  • Volume in males is 5-6 liters, in females is 4-5 liters.

Blood Components

  • Blood plasma makes up 55% of blood.
  • Formed elements constitute 45% of blood.

Blood Plasma

  • Contains 7% proteins, 91.5% water, and 1.5% other solutes.

Formed Elements

  • Include platelets, white blood cells, and red blood cells.

Red Blood Cells (Erythrocytes)

  • Are biconcave discs, 7-8 micrometers in diameter.
  • Lack a nucleus and other organelles.
  • Specialized for oxygen transport.
  • Live for approximately 120 days.
  • Contain hemoglobin, which is responsible for oxygen and nutrient delivery.
  • Count ranges from 4.5 to 5.8 million.

White Blood Cells (Leukocytes)

  • Have nuclei and organelles, but no hemoglobin.
  • Normal count ranges from 5,000 to 10,000.
  • Classified as either granular or agranular.

Granular Leukocytes

  • Types include neutrophils, eosinophils, and basophils.

Neutrophils

  • Make up 60-70% of WBCs.
  • Have 2-5 lobed nuclei.
  • Function in phagocytosis and destruction of bacteria and fungi.

Eosinophils

  • Make up 2-4% of WBCs.
  • Have bilobed nuclei.
  • Combat parasites and mediate allergic responses.

Basophils

  • Make up 0.5-1% of WBCs.
  • Have bilobed or trilobed nuclei.
  • Mediate inflammatory responses.

Agranular Leukocytes

  • Types include lymphocytes and monocytes.

Lymphocytes

  • Make up 20-25% of WBCs.
  • Have eccentric nuclei.
  • Kill viruses and produce antibodies.

Monocytes

  • Make up 3-8% of WBCs.
  • Have kidney-shaped nuclei.
  • Remove dead cells and differentiate into macrophages.

Immune Response and WBCs

  • Bacterial infections trigger an increase in neutrophils.
  • Viral infections lead to increased lymphocytes and monocytes
  • Allergic reactions stimulate eosinophils and basophils.

Platelets (Thrombocytes)

  • Have a lifespan of 5-9 days.
  • Promote blood clotting.
  • Aged and dead platelets are removed by macrophages in the spleen and liver.
  • Normal count ranges from 150,000 to 400,000.

Blood Groups and Types

  • Erythrocyte surfaces contain genetically determined antigens (glycoproteins and glycolipids).
  • Blood types are based on the presence or absence of these antigens.

Rhesus (Rh) Blood Group

  • Rh positive indicates the presence of the Rh antigen on RBCs and the absence of Rh antibodies.
  • Rh negative indicates the absence of the Rh antigen on RBCs and the presence of Rh antibodies.

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