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Questions and Answers
What is the most common type of anemia?
Which factor is associated with the highest risk for iron deficient anemia?
What is the most sensitive test for iron deficient anemia (IDA)?
Which test measures the available transferrin that is left unbound to iron?
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What is a diagnostic manifestation of iron deficient anemia (IDA)?
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What are the clinical manifestations of moderate iron deficient anemia (IDA)?
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What is the main function of albumins in the plasma?
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What are the primary components of plasma proteins?
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Which organ is responsible for fetal hematopoiesis and filtering the blood?
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What is the primary role of thrombocytes in the blood?
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What is the function of pluripotent cells in the bone marrow?
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Why are erythrocytes able to return to their normal shape after squeezing through microcirculation?
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Where are lymphocytes and mononuclear phagocytes primarily produced?
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What is the most common cause of iron deficient anemia (IDA)?
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Which test is used to indirectly measure the saturation of transferrin with iron?
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What is the primary site where ferritin, a protein that stores iron, is produced?
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Which clinical manifestation is likely to be observed in a patient with moderate iron deficient anemia (IDA)?
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What diagnostic manifestation is typically observed in iron deficient anemia (IDA) when assessing the transferrin saturation indirectly?
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Which factor presents a good sign of malignancy for postmenopausal women and men in the context of iron deficient anemia (IDA)?
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What is the primary stimulus for the conversion of yellow bone marrow to hematopoietic red marrow?
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Which organ primarily produces erythropoietin in the body?
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What is the function of reticulocytes in erythropoiesis?
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What is the primary role of heme in the erythrocyte?
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Which enzyme deficiency results in RBC damage and death due to the lack of glycolysis?
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What is the primary cause of hereditary hemolysis?
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What is the term for the presence of RBCs in various shapes?
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What are the classic clinical manifestations of reduced oxygen carrying capacity?
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What lab value is related to the size of red blood cells?
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What does MCH (Mean Corpuscular Hemoglobin) measure?
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Which condition may affect the ability of hemoglobin to carry and transport oxygen?
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What does an increased reticulocyte count indicate?
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What is the primary function of thrombocytes in the blood?
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What is the main function of albumins in the plasma?
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Why do erythrocytes have a limited life span of 120 days?
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What is the primary role of pluripotent cells in the bone marrow?
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Which organ is the largest secondary lymphoid organ?
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What is the function of lipoproteins in plasma?
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Why are thrombocytes incapable of mitotic division?
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What is the primary function of leukocytes in the blood?
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How do erythrocytes enable torpedo shape to squeeze through microcirculation?
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Where does hematopoiesis primarily occur in adults?
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What is the primary fluid component of blood plasma?
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What is the primary function of primary lymphoid organs?
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Which diagnostic manifestation is typically observed in iron deficient anemia (IDA) when assessing the total iron binding capacity (TIBC)?
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What is the primary cause of hereditary hemolysis?
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Which factor is associated with the highest risk for iron deficient anemia?
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What does a low serum iron level and high TIBC indicate in iron deficient anemia (IDA)?
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Why are pica and koilonychia considered as clinical manifestations of moderate iron deficient anemia (IDA)?
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What is the primary stimulus for the conversion of yellow bone marrow to hematopoietic red marrow?
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What enzyme deficiency results in RBC damage and death due to the lack of glycolysis?
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Which organ primarily produces erythropoietin in the body?
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What is the function of reticulocytes in erythropoiesis?
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Why are thrombocytes incapable of mitotic division?
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What is the primary role of heme in the erythrocyte?
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What lab value is related to the size of red blood cells?
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What is the most common type of anemia associated with hereditary hemolysis?
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What test measures the available transferrin that is left unbound to iron?
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What does an increased reticulocyte count indicate?
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Where does hematopoiesis primarily occur in adults?
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What enzyme is involved in protecting the RBC against oxidative stress?
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What is the primary function of plasma proteins in blood?
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What is the role of thrombocytes in the blood?
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Where does hematopoiesis primarily occur in adults?
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What is the main function of pluripotent cells in the bone marrow?
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What is the primary role of leukocytes in the blood?
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What is the significant function of plasma in blood?
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What is the primary function of primary lymphoid organs?
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What lab value is related to the size of red blood cells?
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What is the function of lipoproteins in plasma?
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What is the main function of serum derived from plasma?
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Which type of cells have membrane-bound granules in the cytoplasm and are capable of destroying microorganisms?
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What is the primary role of chemokines in the immune system?
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What is the main function of interferon in the immune system?
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What are the systemic manifestations of the inflammatory response?
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Which of the following biochemicals is responsible for vasoconstriction and platelet activation?
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What is the primary function of Von Willebrand Factor (vWF) in the clotting process?
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Which pathway is activated in response to damage to the inside of blood vessels or blood?
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What is the impact of protein C deficiency in the clotting system?
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What is the consequence of Factor V Leiden mutation?
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Which molecule serves as a first line of defense in innate immunity by being toxic to microorganisms?
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Which cells play a role in the second line of defense through their role in the inflammatory response?
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What is the primary function of natural killer (NK) cells in innate immunity?
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What is the role of thromboxane A2 in platelet activation?
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Which pathway is most dominant and is activated when tissue factor is released by damaged endothelial cells?
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What is the consequence of protein S deficiency in the clotting system?
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What are the cardinal signs of inflammation?
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Which plasma protein system forms a clot, prevents the spread of infection, and provides a framework for repair and healing?
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Which type of cells produce memory cells that are able to respond more rapidly and efficiently upon subsequent exposure to the same antigen?
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What is the precise recognition portion on an antigen called?
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Which plasma protein system functions in anaphylaxis, mast cell degranulation, leukocyte chemotaxis, and cell lysis?
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Which cell type predominantly responds to neutrophil chemotactic factor released during mast cell degranulation?
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Which component of the plasma proteins provides a biochemical barrier against invading pathogens and promotes wound healing?
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Which cell type is primarily responsible for connecting the innate and adaptive immune responses?
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What is the function of antibodies/immunoglobulins produced by plasma cells?
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Which cellular mediator is contained in tissue close to vessels and acts as an activator of inflammation?
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What is the primary role of monocytes and macrophages in the late inflammatory response?
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Which receptor on smooth muscle cells causes bronchoconstriction upon activation?
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Which type of cells are involved in both inflammatory and immune functions, have membrane-bound granules in the cytoplasm, and migrate through vessel walls to sites where they are needed?
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Which proteins act directly on the hypothalamus to cause fever as part of the systemic manifestations of inflammation?
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Which plasma proteins are involved in attracting leukocytes to the site of inflammation as part of the local manifestations of inflammation?
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Which type of immune response do interleukins enhance?
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What is the primary function of Von Willebrand factor (vWF) in the clotting process?
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What is the consequence of protein C deficiency in the clotting system?
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Which pathway is activated when tissue factor (tissue thromboplastin) is released by damaged endothelial cells?
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What is the role of Factor V Leiden in the clotting process?
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Which plasma protein system functions in anaphylaxis, mast cell degranulation, leukocyte chemotaxis, and cell lysis?
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What cellular mediator is contained in tissue close to vessels and acts as an activator of inflammation?
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What is the primary role of antibodies/immunoglobulins produced by plasma cells?
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What is the primary function of natural killer (NK) cells in innate immunity?
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What enzyme deficiency results in RBC damage and death due to the lack of glycolysis?
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What is the primary function of albumins in the plasma?
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What are the primary components released by platelet granules during activation?
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What is the primary role of neutrophils in the early inflammatory response?
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Which plasma protein system functions to destroy pathogens directly, prevent injury to host tissue, and guarantee activation when needed?
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What is the function of antigenic determinant (epitope) on an antigen?
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Which cellular mediator is an activator of inflammation and is contained in tissue close to blood vessels?
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What is the primary function of immunoglobulins (antibodies) produced by plasma cells?
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Which type of blood vessel does histamine cause temporary rapid constriction and dilation of?
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What is the primary function of T cells in the immune response?
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What do memory cells produced by B and T cells enable the body to do more rapidly and efficiently upon subsequent exposure to the same antigen?
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What is the role of plasma proteins in providing a biochemical barrier against invading pathogens?
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What is the primary function of monocytes and macrophages in the late inflammatory response?
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What is the primary role of bradykinin in the kinin system?
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Which component influences the degree of immunogenicity of an antigen by being foreign to the host, appropriate size, adequate chemical complexity, and present in sufficient quantity?
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What is the role of chemokines in the immune system?
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Which type of cells are involved in both inflammatory and immune functions, have membrane-bound granules in the cytoplasm, and migrate through vessel walls to sites where they are needed?
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What is the primary function of interferon in the immune system?
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What are the systemic manifestations of the inflammatory response?
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Which of the following is a cardinal sign of inflammation?
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Which plasma protein system functions in anaphylaxis, mast cell degranulation, leukocyte chemotaxis, and cell lysis?
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Which type of cells are responsible for humoral immunity mediated by circulating antibodies?
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Which plasma protein system provides a biochemical barrier against invading pathogens and promotes wound healing?
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What is the primary role of monocytes and macrophages in the late inflammatory response?
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Which plasma protein system functions to destroy pathogens directly and is involved in leukocyte chemotaxis?
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Which cells are involved in activation of the adaptive immune response?
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What is the primary function of T cells in the immune response?
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What is the function of immunoglobulins (antibodies) in the immune system?
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What do antigenic determinants (epitopes) represent on an antigen?
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Which cells are primarily responsible for histamine release during inflammation?
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What is the main function of complement system in the immune response?
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Which biochemical released by platelet granules stimulates activation of new platelets and causes vasoconstriction?
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What is the function of Von Willebrand Factor (vWF) in the clotting process?
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Which molecule serves as a check and balance in the clotting system by breaking down clotting factors to prevent excessive clotting?
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What is the consequence of Von Willebrand's disease?
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What is the primary consequence of protein S deficiency in the clotting system?
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What is the main consequence of Factor V Leiden mutation?
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Which pathway is MOST DOMINANT and is activated when tissue factor is released by damaged endothelial cells?
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What serves as the first line of defense in innate immunity through physical barriers like skin and epithelial cell linings, and antimicrobial peptides toxic to microorganisms?
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Which type of leukemia is most common in children under the age of 15?
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Which type of leukemia is associated with CNS involvement, increased LDH, and rapid leukemic cell proliferation?
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Which type of leukemia can transform to acute leukemia in a blast crisis characterized by accelerated blast and promyelocyte production?
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Which type of leukemia is the most common in the western world and is least aggressive?
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What is the microorganism responsible for causing rubella?
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Which microorganism is responsible for causing West Nile Virus?
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What is the primary microorganism responsible for causing Rocky Mountain spotted fever?
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Which microorganism is responsible for causing tinea (ringworm)?
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What is the primary microorganism responsible for causing malaria?
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Which microorganism is responsible for causing toxoplasmosis?
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What is the primary feature of Hodgkin's lymphoma?
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Which type of leukemia is most common in children under the age of 15 and is very responsive to therapy?
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Which leukemia type is normally discovered on routine complete blood count (CVC) and is most common in individuals over 60 years old?
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Which leukemia type is associated with the Philadelphia chromosome translocation t(9,22) and can transform to acute leukemia with blast crisis?
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Which type of leukemia has the CM feature of pancytopenia, recurrent infections, splenomegaly, and hepatomegaly as part of its clinical presentation?
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Which type of leukemia is most common in children under the age of 15 and is very responsive to therapy?
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Which type of leukemia is normally discovered on routine complete blood count (CVC) and is most common in individuals over 60 years old?
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Which type of leukemia has CNS involvement associated with B cell phenotype, increased LDH, and rapid leukemic cell proliferation?
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Which type of leukemia can transform to acute leukemia with blast crisis and is associated with the Philadelphia chromosome translocation t(9,22)?
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Which virus is responsible for causing mumps?
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What is the primary microorganism responsible for causing rubella (German measles)?
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Which disease is characterized by a fever and generalized pruritic vesicular rash?
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What microorganism is responsible for causing Lyme disease?
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Which microorganism is responsible for pertussis, also known as 'whooping cough'?
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What is the primary microorganism responsible for causing tinea (ringworm)?
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Which microorganism is responsible for causing parasitic infection malaria?
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What microorganism is responsible for causing toxoplasmosis?
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What type of plasma cell disorder is characterized by neoplastic proliferation of single plasma cell line and monoclonal immunoglobulin production?
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What cancer of the lymphatic system is associated with Ann Arbor staging and lymphadenopathy?
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What group of tumors that occur with malignant transformation and growth of B or T lymphocytes or their precursors in the lymphatic system make up approximately 85% of all cases?
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Which type of leukemia is most common in children under age 15 and is very responsive to therapy?
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Which type of leukemia is associated with translocation of t(9,22) - Philadelphia chromosome and shorter survival with decreased response to treatment?
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Which leukemia type is normally asymptomatic and discovered on routine complete blood count (CVC), and is most common in individuals over 60 years old?
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Which type of leukemia can transform to acute leukemia in blast crisis characterized by accelerated blast and promyelocyte production?
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Which virus is responsible for causing German measles?
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What is the primary microorganism responsible for causing Rocky Mountain spotted fever?
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What is the microorganism responsible for causing tinea or ringworm?
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Which microorganism is responsible for causing malaria?
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Which microorganism is responsible for causing parasitic infection toxoplasmosis?
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Which microorganism is responsible for causing West Nile Virus?
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What microorganism is responsible for causing pertussis, also known as 'whooping cough'?
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Which microorganism is responsible for causing Smallpox?
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'Leukemias' are characterized by neoplastic proliferation of abnormal white blood cells. Which type of leukemia involves lymphocytes?
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'Hodgkin's lymphoma' is a cancer of the lymphatic system. What staging system is commonly used to stage Hodgkin's lymphoma?
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What microorganism is responsible for causing Roseola?
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Which microorganism causes scarlet fever?
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Description
mix of medium and hard questions. 197 questions total