Blood Composition and Function
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Questions and Answers

What is the main difference between serum and plasma in terms of composition?

  • Serum contains fibrinogen and clotting factors.
  • Plasma contains serum and red blood cells.
  • Serum is plasma minus fibrinogen and all clotting factors. (correct)
  • Plasma contains more nutrients than serum.
  • What is the correct procedure for obtaining plasma from whole blood?

  • Use a pipette to collect blood directly from the syringe.
  • Transfer blood to a container without anticoagulant and wait for it to clot.
  • Centrifuge anti-coagulated blood at 2500 rpm for 20-30 minutes. (correct)
  • Allow blood to sit at room temperature for several hours.
  • What happens to red blood cells during the process of centrifuging blood to obtain plasma?

  • They remain suspended in the supernatant fluid.
  • They convert into serum over time.
  • They form a packed layer at the bottom of the tube. (correct)
  • They are completely dissolved in the plasma.
  • In the diagram comparing serum and plasma, what is indicated by the yellow liquid?

    <p>Serum, which is plasma without clotting factors.</p> Signup and view all the answers

    How long should blood remain in a container to form serum before pipetting?

    <p>For one to two hours.</p> Signup and view all the answers

    What is the primary function of blood concerning homeostasis?

    <p>Temperature regulation</p> Signup and view all the answers

    Which component makes up the largest percentage of blood by volume?

    <p>Plasma</p> Signup and view all the answers

    What is the primary purpose of albumin in blood plasma?

    <p>Maintenance of osmotic pressure</p> Signup and view all the answers

    How many white blood cells are typically found per cubic millimeter of blood?

    <p>5,000-10,000</p> Signup and view all the answers

    Which of the following is a function of blood?

    <p>Stoppage of bleeding</p> Signup and view all the answers

    What percentage of blood volume do formed elements account for?

    <p>45%</p> Signup and view all the answers

    Which plasma protein has the highest concentration?

    <p>Albumin</p> Signup and view all the answers

    What percentage of red blood cells is typically found in the blood?

    <p>4.2-6.2 million per cubic mm</p> Signup and view all the answers

    Which blood sample type is most commonly used for routine laboratory tests?

    <p>Venous sample</p> Signup and view all the answers

    What is a common use for arterial blood samples?

    <p>Blood pH and arterial blood gases</p> Signup and view all the answers

    Which type of blood sample is taken from the fingertip or heel?

    <p>Capillary sample</p> Signup and view all the answers

    What characteristic of veins allows them to accommodate larger volumes of blood?

    <p>Thin walls and wide lumens</p> Signup and view all the answers

    What is the primary function of globulins in the blood?

    <p>Defensive function and transportation of substances</p> Signup and view all the answers

    Which of the following samples is NOT suitable for hematological tests?

    <p>Hemolyzed samples</p> Signup and view all the answers

    Which blood condition is characterized by a decrease in red blood corpuscles?

    <p>Anemia</p> Signup and view all the answers

    Which is true about the structure of arteries?

    <p>They have thick walls and narrow lumens</p> Signup and view all the answers

    Why are capillary blood tests often less reliable for certain values?

    <p>Sample dilution from tissue fluid</p> Signup and view all the answers

    What is the range for white blood corpuscles in a healthy individual?

    <p>4000 to 11000 per cubic mm</p> Signup and view all the answers

    What is the preferred method for blood sample collection in infants?

    <p>Capillary sample from the heel</p> Signup and view all the answers

    What is the function of fibrinogen in the blood?

    <p>To aid in blood clotting</p> Signup and view all the answers

    What happens to samples if even a small clot forms in anti-coagulated blood?

    <p>They can negate the test results</p> Signup and view all the answers

    What term describes the increase in white blood corpuscles?

    <p>Leucocytosis</p> Signup and view all the answers

    What is the correct sequence of blood vessels starting from the heart?

    <p>Arteries → Arterioles → Capillary Bed → Venules → Veins</p> Signup and view all the answers

    What describes the role of platelets in the blood?

    <p>Blood clotting</p> Signup and view all the answers

    Study Notes

    Blood Composition and Function

    • Blood is a vital fluid tissue, making up 8% of body weight (approximately 5.6 liters).
    • Blood's functions include: transport, defense (e.g., stopping bleeding), and homeostasis.

    Blood Composition Breakdown

    • Plasma (55%): Mostly water (91%), with proteins (7%), and other solutes (2%).

      • Plasma proteins include albumin (osmotic pressure, transport), globulins (defense, transport), fibrinogen (blood clotting).
      • Other solutes include ions, nutrients, waste products, gases, and regulatory substances.
    • Formed elements (45%):

      • Red blood cells (RBCs): 4.2-6.2 million per cubic mm. Low RBCs is anemia; high RBCs is polycythemia.
      • White blood cells (WBCs): 4000-11000 per cubic mm. Low WBCs is leukopenia; high WBCs is leukocytosis. Types include neutrophils, lymphocytes, monocytes, eosinophils, and basophils.
      • Platelets: 250,000-500,000 per cubic mm. Low platelets is thrombocytopenia; high platelets is thrombocytosis.

    Blood Vessels

    • Arteries: Carry blood away from the heart; thick walls, narrow lumens, less distensible.
    • Veins: Carry blood to the heart; thinner walls, wider lumens, more distensible (can store more blood).

    Blood Sampling Types

    • Venous blood: From superficial veins (preferred for most clinical tests). Infants may use the femoral vein.
    • Arterial blood: From arteries (used for blood gas analysis and pH). Radial or femoral arteries are often used.
    • Capillary blood: From fingertips, heels, earlobes (used for Hb estimation, cell counts, coagulation time, blood groups in infants & children, and patients with fragile veins).

    Unsuitable Blood Samples for Hematological Tests

    • Clotted blood: Even small clots invalidate results.
    • Hemolysed blood: Red blood cell rupture releases hemoglobin, rendering the sample unusable.

    Blood Sample Processing

    • Whole blood/Plasma: Blood withdrawn is mixed with an anticoagulant. If plasma is desired, centrifugation separates plasma from formed elements.
    • Serum: Blood draws are allowed to clot; the supernatant is collected as serum. Centrifugation helps remove any remaining cells.

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    Description

    Explore the vital roles and composition of blood in this quiz. Learn about the components such as plasma and formed elements, along with their functions in transport, defense, and homeostasis. Test your knowledge on blood cell counts and the significance of variations in these counts.

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