Blood Composition and Function Quiz
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Questions and Answers

If a patient's blood sample appears dark red, what is the most likely explanation?

  • The patient's blood has a lower than normal oxygen level. (correct)
  • The patient is experiencing hypothermia, causing the blood to darken.
  • The patient's blood is highly oxygenated due to efficient respiratory function.
  • The patient has a high concentration of erythrocytes, increasing blood viscosity.

Which statement accurately describes the roles of different components within the cardiovascular system regarding blood transport?

  • Capillaries directly pump blood throughout the body, maintaining constant pressure.
  • The heart pumps blood, arteries transport blood away from the heart, and veins transport blood toward the heart. (correct)
  • Arteries carry blood towards the heart, while veins carry blood away from the heart.
  • The heart facilitates the exchange between blood and body tissues, while capillaries pump the blood.

How would an increased concentration of solutes in the blood plasma primarily affect the movement of fluids in the body?

  • It would increase osmosis, causing water to move out of the blood into surrounding tissues.
  • It would decrease osmosis, causing water to move into the blood from surrounding tissues.
  • It would increase osmosis, causing water to move into the blood from surrounding tissues. (correct)
  • It would have no impact on osmosis, maintaining a stable fluid balance.

If a person's blood pH is measured at 7.30, what condition might this indicate and why?

<p>Acidosis, because the blood pH is slightly below the normal range. (A)</p> Signup and view all the answers

Which characteristic of blood is most directly affected by a significant increase in the number of erythrocytes?

<p>Blood viscosity, causing it to become thicker. (B)</p> Signup and view all the answers

Why is maintaining appropriate blood pH crucial for plasma protein integrity?

<p>Significant pH alterations denature plasma proteins, which compromises their structure and function. (C)</p> Signup and view all the answers

How does testosterone affect hematocrit levels in adult males, and what physiological mechanism explains this?

<p>Testosterone causes more erythropoietin secretion by the kidney, which stimulates erythropoiesis and increases hematocrit. (B)</p> Signup and view all the answers

In a centrifuged blood sample, what component occupies the greatest volume and what is its primary function?

<p>Erythrocytes, which primarily transport oxygen throughout the body. (B)</p> Signup and view all the answers

What cellular characteristics differentiate leukocytes from erythrocytes in a blood smear?

<p>Leukocytes are larger and possess a noticeable nucleus, while erythrocytes are smaller, more numerous, and lack a nucleus. (C)</p> Signup and view all the answers

How would severe dehydration likely affect a person's hematocrit, and what is the underlying mechanism?

<p>Dehydration would increase hematocrit by decreasing plasma volume, which concentrates red blood cells. (C)</p> Signup and view all the answers

How do plasma proteins contribute to maintaining blood volume and blood pressure?

<p>By exerting colloid osmotic pressure, preventing fluid loss from the blood. (A)</p> Signup and view all the answers

What is the likely consequence of a liver disease that significantly reduces the production of plasma proteins?

<p>Fluid loss from blood and subsequent tissue swelling (edema). (B)</p> Signup and view all the answers

Why do nonpolar molecules require carrier proteins for transport in the blood?

<p>Because nonpolar molecules are repelled by the polar nature of plasma. (C)</p> Signup and view all the answers

Which of the following is the most abundant plasma protein and what is its primary function related to blood pressure?

<p>Albumin; maintains colloid osmotic pressure to help maintain blood volume. (A)</p> Signup and view all the answers

What is the significance of blood being considered a solution in the context of its composition?

<p>It means that blood contains a uniform mixture of dissolved substances which can be easily transported. (C)</p> Signup and view all the answers

If a patient's blood test reveals a significantly low level of albumin, which of the following physiological changes would be most expected?

<p>Accumulation of fluid in tissues (edema). (A)</p> Signup and view all the answers

Which characteristic of substances dictates whether they dissolve directly in blood plasma or require a carrier protein?

<p>Their polarity or charge. (D)</p> Signup and view all the answers

How do LDL and HDL contribute to the function of blood plasma?

<p>They act as transport proteins for lipids. (D)</p> Signup and view all the answers

Where does hematopoiesis primarily occur in the human body?

<p>Red bone marrow of certain bones (C)</p> Signup and view all the answers

Which of the following is NOT a type of formed element production during hematopoiesis?

<p>Osteogenesis (B)</p> Signup and view all the answers

What structural characteristic of erythrocytes enables them to efficiently transport oxygen and carbon dioxide?

<p>Biconcave disc shape (D)</p> Signup and view all the answers

What is the primary role of hemoglobin within erythrocytes?

<p>To transport oxygen and carbon dioxide (A)</p> Signup and view all the answers

A single hemoglobin molecule can bind a maximum of how many oxygen molecules?

<p>Four (A)</p> Signup and view all the answers

Which component of the hemoglobin molecule directly binds to oxygen?

<p>The iron ion (B)</p> Signup and view all the answers

What is the role of erythropoietin (EPO) in the production of red blood cells?

<p>It stimulates the production of red blood cells (B)</p> Signup and view all the answers

How does testosterone affect erythropoietin (EPO) production and consequently, erythrocyte count?

<p>Testosterone stimulates EPO production, leading to higher erythrocyte counts. (D)</p> Signup and view all the answers

How would an endurance athlete using EPO as a form of blood doping benefit?

<p>Increased oxygen delivery to muscles, improving endurance (C)</p> Signup and view all the answers

How does altitude affect EPO levels in the body?

<p>Altitude increases EPO levels due to decreased oxygen availability. (D)</p> Signup and view all the answers

Why does a second exposure to Rh+ blood in an Rh- individual result in a transfusion reaction?

<p>Anti-Rh antibodies, formed after the first exposure, recognize and agglutinate the Rh+ erythrocytes. (A)</p> Signup and view all the answers

During a blood transfusion, agglutination occurs because:

<p>The recipient's antibodies bind to the transfused erythrocytes, causing them to clump together. (C)</p> Signup and view all the answers

In the context of ABO blood types, what determines a person's blood type?

<p>The specific antigens present on the surface of their erythrocytes. (C)</p> Signup and view all the answers

Why is it critical to determine a patient's blood type before performing a blood transfusion?

<p>To prevent agglutination and potential blockage of blood vessels. (D)</p> Signup and view all the answers

Consider a scenario where a patient with type A blood receives a transfusion of type B blood. What immediate physiological response is most likely to occur?

<p>Agglutination of erythrocytes, potentially leading to blocked blood vessels. (A)</p> Signup and view all the answers

An individual with blood type O is considered a 'universal donor' because:

<p>Their blood lacks A and B antigens, so it won't trigger an immune response in recipients with type A, B, or AB blood. (D)</p> Signup and view all the answers

If a mother is Rh- and the fetus is Rh+, under what circumstances might Rh incompatibility pose a risk?

<p>During subsequent pregnancies with Rh+ fetuses, if the mother has been sensitized. (C)</p> Signup and view all the answers

What is the primary function of performing an agglutination test in blood typing?

<p>To determine the presence or absence of specific antigens on erythrocytes. (A)</p> Signup and view all the answers

Flashcards

Hematocrit

The percentage of blood volume occupied by erythrocytes.

Normal Hematocrit Ranges

Adult males: 42–56%; Adult females: 38–46%.

Blood Smear

A thin layer of blood on a slide, stained to observe different cells.

Erythrocytes Appearance

Most numerous formed elements, are pink, anucleate, and biconcave.

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Leukocytes vs Erythrocytes

Leukocytes are larger with a nucleus, while erythrocytes lack one.

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Functions of Blood

Blood moves gases, nutrients, wastes, and hormones throughout the body.

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Cardiovascular System

System that includes the heart and blood vessels to transport blood.

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Blood Volume

Normal adult blood volume is approximately 5,000 cc (5 liters).

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Blood Viscosity

The thickness of blood, higher with more erythrocytes (red blood cells).

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Blood pH

Blood pH ranges from 7.35 to 7.45, slightly alkaline.

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Plasma Composition

Plasma is a liquid component of blood, containing dissolved substances like electrolytes, nutrients, and gases.

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Plasma Proteins

Proteins in plasma act as transporters for lipids, hormones, and ions; examples include LDL and HDL.

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Colloid Osmotic Pressure

Pressure exerted by plasma proteins that helps retain fluid in blood vessels and maintain blood pressure.

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Albumin

Most abundant plasma protein, crucial for maintaining osmotic pressure and preventing fluid loss.

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Dissolved Substances in Plasma

Includes organic and inorganic molecules, such as electrolytes, nutrients, gases, and waste products.

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Transport Proteins Example

LDL and HDL are examples of plasma proteins that transport lipids in the bloodstream.

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Fluid Loss in Diseases

Decreased plasma protein levels due to diseases can cause fluid loss from blood, leading to swelling in tissues.

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Diseases Affecting Plasma Proteins

Conditions like liver disease can lower plasma protein production, affecting colloid osmotic pressure and fluid balance.

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Hematopoiesis

The process of producing blood cells in the bone marrow.

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Erythropoiesis

The production of red blood cells (erythrocytes).

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Leukopoiesis

The production of white blood cells (leukocytes).

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Thrombopoiesis

The production of platelets from megakaryocytes.

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Erythrocyte Structure

Biconcave discs lacking a nucleus, packed with hemoglobin.

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Hemoglobin

A red-pigmented protein that binds oxygen and carbon dioxide.

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Oxygen Binding

Hemoglobin can bind four oxygen molecules through iron ions.

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Erythropoietin (EPO)

A hormone that stimulates erythropoiesis, increasing red blood cell production.

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Testosterone and EPO

Testosterone increases EPO production, leading to higher red blood cell count in males.

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Environmental Factors on EPO

Altitude and other factors can influence erythropoietin levels in the body.

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Rh Blood Group

A blood group determined by the presence of Rh factor protein on red blood cells.

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Rh Positive

Blood type where the Rh factor is present on red blood cells (Rh+).

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Rh Negative

Blood type without the Rh factor on red blood cells (Rh-).

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Anti-Rh Antibodies

Antibodies formed in Rh- individuals who receive Rh+ blood.

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Transfusion Reaction

A harmful response when an incompatible blood type is transfused.

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Agglutination

The clumping of red blood cells due to antibody binding.

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Rh Incompatibility

A situation where an Rh- mother carries an Rh+ baby, risking RBC damage.

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Clinical Considerations of Transfusion

Understanding the risks of transfusion reactions and their effects.

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Study Notes

Blood Overview

  • Blood is a continuously regenerated connective tissue
  • It transports gases, nutrients, wastes, and hormones throughout the body
  • Blood is transported through the cardiovascular system
  • The heart pumps blood
  • Arteries carry blood away from the heart
  • Veins carry blood towards the heart
  • Capillaries allow exchange between blood and body tissues

Functions of Blood

  • Transportation:
    • Carries oxygen from the lungs to tissues
    • Transports nutrients from the digestive tract to tissues
    • Carries hormones from endocrine glands to target cells
    • Transports metabolic waste products to the excretory organs
  • Regulation:
    • Regulates blood pH
    • Maintains body temperature
    • Maintains water balance in cells
  • Protection:
    • White blood cells (WBCs) protect against disease by phagocytosis
    • Blood is a reservoir for substances like water and electrolytes
    • Blood performs hemostasis (the process of stopping blood loss)

Physical Characteristics of Blood

  • Color: High oxygen = bright red; Low oxygen = dark red
  • Volume: Approximately 5 liters in a normal adult
  • Viscosity: Thick; high erythrocyte concentration = high viscosity
  • Solutes Concentration: Influences osmosis direction
  • Temperature: Slightly higher than body temperature (one degree Celsius)
  • pH: 7.35 to 7.45; slightly alkaline, crucial for plasma protein integrity

Whole Blood Separation

  • Whole blood is separated into three components during centrifugation
  • Plasma (55%): Primarily water, proteins (albumin, globulins, fibrinogen), other solutes
  • Buffy coat (<1%): A thin layer containing platelets and leukocytes (white blood cells)
  • Erythrocytes (44%): Red blood cells, containing hemoglobin; crucial for oxygen transport

Hematocrit

  • Percentage of volume in all formed elements, mainly erythrocytes
  • Adult males: 42-56%
  • Adult females: 38-46%

Formed Elements in Blood

  • Erythrocytes (Red Blood Cells): Most numerous, biconcave discs, anucleate, filled with hemoglobin, transport oxygen and carbon dioxide
  • Leukocytes (White Blood Cells): Larger than erythrocytes, various types with diverse functions (e.g., neutrophils, lymphocytes)
  • Platelets: Small fragments of cells, involved in blood clotting

Blood Types (ABO)

  • ABO blood groups: Categorizes blood based on the presence or absence of A and B antigens on erythrocytes
  • Rh factor: Another blood antigen system; person is positive if the Rh factor is present on erythrocytes

Erythropoiesis

  • Erythropoiesis is the production of red blood cells, regulated by erythropoietin (EPO)
  • EPO is produced in the kidneys when blood oxygen levels are low
  • Testosterone also stimulates EPO production, influencing erythrocyte counts
  • Environmental factors like altitude affect EPO levels

Erythrocyte Fate and Destruction

  • Aged or damaged erythrocytes are eliminated by macrophages in the liver and spleen
  • Hemoglobin is broken down into heme and globin
  • Heme is converted to bilirubin, transported to the liver, and excreted in bile
  • Iron from hemoglobin is recycled for erythrocyte production elsewhere

Blood Proteins and Osmotic Pressure

  • Plasma proteins, particularly albumin, exert colloid osmotic pressure
  • This pressure helps maintain blood volume and prevents fluid loss from capillaries
  • Deficiencies in plasma proteins can cause fluid imbalances and swelling.

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Blood Part 1 (4) - Week 3 PDF

Description

Test your knowledge of blood composition, pH balance, and the roles of erythrocytes and leukocytes. Explore the impact of solute concentrations, dehydration, and hormonal influences on blood characteristics. Understand the crucial relationship between blood pH and plasma protein integrity.

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