quiz 6-7 lab

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What is the primary function of fibrinogen within the plasma?

  • Forming blood clots (correct)
  • Buffering pH levels
  • Transporting oxygen
  • Providing immunity

Which of the following is NOT a formed element of blood?

  • Erythrocytes
  • Thrombocytes
  • Globulin (correct)
  • Leukocytes

What percentage of total blood volume do formed elements comprise?

  • 10%
  • 55%
  • 45% (correct)
  • 90%

What is the clinical significance of a low hematocrit (HCT) value?

<p>Anemia (B)</p>
Signup and view all the answers

Which adaptation of red blood cells (RBCs) directly facilitates their passage through narrow capillaries?

<p>Flexibility (A)</p>
Signup and view all the answers

What is the primary function of neutrophils?

<p>Phagocytose bacteria (D)</p>
Signup and view all the answers

Which type of white blood cell is primarily involved in combating parasitic infections and plays a role in allergic reactions?

<p>Eosinophils (B)</p>
Signup and view all the answers

Which of the following best describes the role of basophils?

<p>Releasing histamine during inflammatory responses (C)</p>
Signup and view all the answers

What is the role of platelets (thrombocytes) in hemostasis?

<p>Forming platelet plugs and releasing clotting chemicals (C)</p>
Signup and view all the answers

Where does the formation of platelets (thrombocytes) primarily occur?

<p>Red bone marrow (D)</p>
Signup and view all the answers

What immunological characteristic defines the universal donor blood type?

<p>Absence of A and B antigens (D)</p>
Signup and view all the answers

Which of the following blood types is considered the universal recipient?

<p>AB+ (D)</p>
Signup and view all the answers

What is the role of erythropoietin (EPO) in regulating hemopoiesis?

<p>Increases red blood cell production (D)</p>
Signup and view all the answers

In what anatomical location is the heart primarily situated?

<p>Thoracic cavity within the mediastinum (D)</p>
Signup and view all the answers

Which of the following vessels carries oxygenated blood from the heart to the body?

<p>Aorta (A)</p>
Signup and view all the answers

What is the main function of the atrioventricular (AV) valves?

<p>To prevent backflow of blood into the atria during ventricular contraction (B)</p>
Signup and view all the answers

Which heart chamber receives deoxygenated blood from the systemic circulation?

<p>Right atrium (B)</p>
Signup and view all the answers

What is the primary purpose of the pulmonary circulation?

<p>To facilitate gas exchange in the lungs (B)</p>
Signup and view all the answers

Which vessel(s) directly supply blood to the heart muscle itself?

<p>Coronary arteries (C)</p>
Signup and view all the answers

Which of the following is a unique structural feature of cardiac muscle tissue?

<p>Intercalated discs (C)</p>
Signup and view all the answers

What is the functional role of the sinoatrial (SA) node in the intrinsic conduction system of the heart?

<p>To initiate the heartbeat as the heart's pacemaker (D)</p>
Signup and view all the answers

Which component of the intrinsic conduction system is responsible for delaying the impulse to allow atrial contraction to complete before ventricular contraction?

<p>AV Node (A)</p>
Signup and view all the answers

In the intrinsic conduction system, what is the function of the Purkinje fibers?

<p>Distributing the signal to the ventricular myocardium (B)</p>
Signup and view all the answers

What does the QRS complex represent on an electrocardiogram (ECG)?

<p>Ventricular depolarization (B)</p>
Signup and view all the answers

What does the T wave on an electrocardiogram (ECG) represent?

<p>Ventricular repolarization (B)</p>
Signup and view all the answers

Which of the following best describes the sequence of electrical events in the heart?

<p>SA Node -&gt; AV Node -&gt; Bundle of His -&gt; Purkinje Fibers (D)</p>
Signup and view all the answers

If a patient has blood type A+, which antigens are present on their red blood cells?

<p>A and Rh antigens (D)</p>
Signup and view all the answers

A patient's lab results show an elevated hematocrit level. Which condition is most likely indicated by this result?

<p>Dehydration (A)</p>
Signup and view all the answers

Which heart chamber is characterized by having the thickest wall and why?

<p>Left ventricle, due to pumping blood to the systemic circulation (B)</p>
Signup and view all the answers

Damage to the anterior interventricular artery would primarily affect blood supply to which region of the heart?

<p>Interventricular septum and anterior ventricles (A)</p>
Signup and view all the answers

A cardiologist observes an absent P wave on a patient's ECG. What does this likely indicate?

<p>Atrial fibrillation (D)</p>
Signup and view all the answers

How would a drug that selectively blocks desmosomes in cardiac intercalated discs affect heart function?

<p>Prevent the synchronization of contractions between cells. (D)</p>
Signup and view all the answers

Which of the following correctly pairs a blood component with its approximate percentage in whole blood and primary function?

<p>Plasma (55%): Transport, homeostasis, clotting, immunity (A)</p>
Signup and view all the answers

During a blood transfusion, agglutination occurs. This reaction is directly caused by:

<p>The recipient's antibodies attacking the donor's antigens. (D)</p>
Signup and view all the answers

A researcher is studying the effects of a drug on erythrocyte production. Which of the following locations would be the most appropriate for observing the direct impact of this drug?

<p>The red bone marrow (A)</p>
Signup and view all the answers

A patient is diagnosed with a condition that impairs the flexibility of their erythrocytes. Which of the following physiological consequences is most likely to occur?

<p>Difficulty passing through capillaries. (D)</p>
Signup and view all the answers

A new drug is developed that inhibits the function of the AV node. What would be the most likely effect on the ECG?

<p>Lengthening of the PR interval. (D)</p>
Signup and view all the answers

Consider an individual with blood type O negative who requires a blood transfusion. What is the underlying immunological reason making O negative the universal donor in such scenarios?

<p>O negative blood lacks A, B, and Rh antigens, preventing the recipient's antibodies from attacking the donor's red blood cells. (C)</p>
Signup and view all the answers

Imagine a hypothetical scenario where the hormone erythropoietin (EPO) receptors are genetically modified to have a tenfold increase in affinity for EPO. What is the most likely long-term physiological consequence of this modification?

<p>Chronic polycythemia leading to increased blood viscosity and potential thrombotic events. (A)</p>
Signup and view all the answers

Which of the following structures is part of the upper respiratory tract?

<p>Pharynx (A)</p>
Signup and view all the answers

What is the primary role of the nasal cavity in respiration?

<p>Conditioning of inspired air (A)</p>
Signup and view all the answers

Which type of epithelium primarily forms the structure of the alveoli?

<p>Simple squamous epithelium (D)</p>
Signup and view all the answers

During inhalation, the contraction of the diaphragm leads to which of the following?

<p>Increase in thoracic cavity volume (D)</p>
Signup and view all the answers

Which of the following processes primarily occurs during exhalation?

<p>Lungs recoil (C)</p>
Signup and view all the answers

Which of the following muscles contract during active inspiration?

<p>Diaphragm and intercostals (D)</p>
Signup and view all the answers

What is the approximate volume of air exchanged during a normal breath, also known as the tidal volume (TV)?

<p>500 mL (C)</p>
Signup and view all the answers

In alveolar gas exchange, which gas diffuses from the alveoli into the capillaries?

<p>Oxygen (B)</p>
Signup and view all the answers

What effect does a decrease in pH (more acidic conditions) have on the affinity of hemoglobin for oxygen?

<p>Decreases oxygen affinity (B)</p>
Signup and view all the answers

How is the majority of carbon dioxide transported in the blood?

<p>As bicarbonate ions (B)</p>
Signup and view all the answers

Which region of the brain sets the basic rhythm for respiration?

<p>Medulla oblongata (B)</p>
Signup and view all the answers

Which of the following stimuli is detected by peripheral chemoreceptors to regulate respiratory rate?

<p>Decreased pH (D)</p>
Signup and view all the answers

Which of the following is a characteristic of restrictive lung diseases?

<p>Decreased lung expansion (C)</p>
Signup and view all the answers

What is the functional consequence of the large surface area in the alveoli?

<p>Enhanced gas exchange efficiency (D)</p>
Signup and view all the answers

Which of the following changes would result in increased oxygen unloading from hemoglobin?

<p>Increased temperature (D)</p>
Signup and view all the answers

If a patient has damage to the apneustic center in the pons, what aspect of respiration is most likely to be affected?

<p>Modulating depth of breathing (B)</p>
Signup and view all the answers

In systemic tissues, what causes oxygen to exit the blood and enter the cells?

<p>Low oxygen concentration in cells (A)</p>
Signup and view all the answers

Which scenario would result in the highest affinity of hemoglobin for oxygen?

<p>Low temperature, high pH, low CO2 (C)</p>
Signup and view all the answers

What is the primary mechanism by which the medulla oblongata regulates the basic rhythm of respiration?

<p>Activating inspiratory neurons (D)</p>
Signup and view all the answers

In the context of carbon dioxide transport, what role does carbonic anhydrase play?

<p>Conversion of carbon dioxide and water to bicarbonate (D)</p>
Signup and view all the answers

How do central chemoreceptors in the medulla respond to increased carbon dioxide levels?

<p>By indirectly detecting H+ ions in the cerebrospinal fluid (CSF) (D)</p>
Signup and view all the answers

Which of the following characteristics distinguishes obstructive lung diseases from restrictive lung diseases?

<p>Airflow obstruction (C)</p>
Signup and view all the answers

How does the warming of inspired air in the nasal cavity benefit the respiratory system?

<p>It prevents damage to the alveoli due to cold air. (D)</p>
Signup and view all the answers

What is the extra air that can be forcefully exhaled after the end of a normal tidal volume called?

<p>Expiratory reserve volume (ERV) (C)</p>
Signup and view all the answers

In systemic tissues, the exchange of gases results in:

<p>Oxygen exiting the blood and carbon dioxide entering cells (A)</p>
Signup and view all the answers

An increase in carbon dioxide levels leads to greater unloading of $O_2$ from hemoglobin. What is the underlying chemical mechanism that directly explains this?

<p>Increased $H^+$ concentration, leading to conformational change (D)</p>
Signup and view all the answers

Which of the following physiological responses would occur if chemoreceptors detect an increase in carbon dioxide ($CO_2$) and a decrease in oxygen ($O_2$) levels in the blood?

<p>Increased respiratory rate and tidal volume (B)</p>
Signup and view all the answers

A patient with pulmonary fibrosis would likely exhibit which of the following?

<p>Decreased lung expansion (D)</p>
Signup and view all the answers

What is the primary function of the pneumotaxic center located in the pons?

<p>To inhibit inspiration and regulate respiratory rate (B)</p>
Signup and view all the answers

A person standing at sea level quickly ascends to the top of a high mountain. How will this change affect the affinity of hemoglobin for oxygen in their blood?

<p>Increase affinity due to decreased arterial $PO_2$ (B)</p>
Signup and view all the answers

Which of the following best describes the process of humidification within the nasal cavity?

<p>Secretion of mucus by goblet cells to add moisture to inhaled air (D)</p>
Signup and view all the answers

How does increased temperature affect oxygen unloading at the tissues?

<p>Reduces hemoglobin affinity, facilitating $O_2$ release. (A)</p>
Signup and view all the answers

A man with chronic obstructive pulmonary disease (COPD) is admitted to the hospital. Which arterial blood gas finding is most expected?

<p>Low $PO_2$ and high $PCO_2$ (D)</p>
Signup and view all the answers

Which of the following compensatory mechanisms is most likely to occur in a person with chronic bronchitis to maintain oxygen delivery to tissues?

<p>Increased heart rate and erythropoiesis (B)</p>
Signup and view all the answers

A researcher is studying the effect of altitude on minute ventilation (the volume of gas inhaled or exhaled from a person's lungs per minute). Which of the following scenarios would result in the greatest increase in minute ventilation?

<p>A decrease in arterial $PO_2$ and increase in arterial $PCO_2$ (D)</p>
Signup and view all the answers

A patient is diagnosed with a rare condition that selectively impairs the function of type II alveolar cells. Which of the following is the most likely consequence of this condition?

<p>Increased alveolar surface tension, leading to alveolar collapse (B)</p>
Signup and view all the answers

Consider a scenario where a person's body temperature drops significantly due to extreme cold exposure. How would this hypothermia directly influence the oxygen-hemoglobin dissociation curve and oxygen delivery to tissues?

<p>Shift the curve to the left, impairing oxygen unloading at the tissues. (C)</p>
Signup and view all the answers

During strenuous exercise, the body produces lactic acid, which lowers the blood pH. How does this change in pH affect oxygen unloading from hemoglobin in the working muscles?

<p>It increases oxygen unloading by decreasing the affinity of hemoglobin for oxygen. (C)</p>
Signup and view all the answers

Flashcards

Plasma

Liquid component of blood (55%), mostly water (90%) + proteins, electrolytes, nutrients, hormones, gases.

Formed Elements

Cellular components of blood (45%) including red blood cells (RBCs), white blood cells (WBCs), and platelets.

Plasma Function: Transport

Transport of nutrients, hormones, waste, and gases.

Plasma Function: Homeostasis

Maintenence of pH buffer and temperature regulation.

Signup and view all the flashcards

Plasma Function: Clotting

Fibrinogen in plasma is essential for blood clot formation.

Signup and view all the flashcards

Plasma Function: Immunity

Globulins (antibodies) in plasma provide immunity.

Signup and view all the flashcards

Formed Elements Definition

Cellular components (RBCs, WBCs, platelets) suspended in plasma.

Signup and view all the flashcards

Erythrocytes

Red blood cells; transport oxygen.

Signup and view all the flashcards

Leukocytes

White blood cells; defend the body against infection.

Signup and view all the flashcards

Thrombocytes

Cell fragments; form blood clots.

Signup and view all the flashcards

Hematocrit (HCT)

Percentage of RBCs in total blood volume.

Signup and view all the flashcards

Red Blood Cells (RBCs)

Biconcave shape, no nucleus, filled with hemoglobin to carry oxygen.

Signup and view all the flashcards

Neutrophils Function

Phagocytose bacteria; first responders to infection.

Signup and view all the flashcards

Eosinophils Function

Combat parasites; involved in allergies.

Signup and view all the flashcards

Basophils Function

Releases histamine and promotes inflammatory responses.

Signup and view all the flashcards

Lymphocytes Function

B cells (produce antibodies) and T cells (cell-mediated immunity).

Signup and view all the flashcards

Monocytes Function

Become macrophages; long-term phagocytosis.

Signup and view all the flashcards

Platelets Function

Hemostasis; platelet plug formation; release of clotting chemicals.

Signup and view all the flashcards

Platelets Formation

Formation is from megakaryocytes in bone marrow, via fragmentation.

Signup and view all the flashcards

Antigens (Agglutinogens)

Antigens on RBC surface (A, B, Rh).

Signup and view all the flashcards

Antibodies (Agglutinins)

Antibodies in plasma that attack non-self antigens.

Signup and view all the flashcards

Transfusion Reactions

Occur if antigens are attacked by recipient's antibodies.

Signup and view all the flashcards

Universal Donor

O- (no antigens).

Signup and view all the flashcards

Universal Recipient

AB+ (no antibodies).

Signup and view all the flashcards

Hemopoiesis (Hematopoiesis)

Formation of blood cells.

Signup and view all the flashcards

Hemopoiesis Location

Red bone marrow (found in flat bones, vertebrae, pelvis, ribs).

Signup and view all the flashcards

Hemopoiesis Regulation

Erythropoietin (EPO) from kidneys increases RBC production.

Signup and view all the flashcards

Cardiac Muscle Histology

Striated, branched, single central nucleus, intercalated discs.

Signup and view all the flashcards

Cardiac Muscle Function

Synchronize contractions, allow ion flow between cells for unified heartbeat.

Signup and view all the flashcards

SA Node (sinoatrial)

Pacemaker; initiates heartbeat.

Signup and view all the flashcards

AV Node (atrioventricular)

Delays signal to allow atrial contraction.

Signup and view all the flashcards

Bundle of His

Conducts signal through septum.

Signup and view all the flashcards

Bundle Branches

Carry signal down septum

Signup and view all the flashcards

Purkinje Fibers

Distribute signal to ventricular myocardium.

Signup and view all the flashcards

ECG: P wave

Atrial depolarization (atria contract).

Signup and view all the flashcards

ECG: QRS complex

Ventricular depolarization (ventricles contract).

Signup and view all the flashcards

ECG: T wave

Ventricular repolarization (ventricles relax).

Signup and view all the flashcards

Upper Respiratory Tract

Structures including the nose, nasal cavity, sinuses, and pharynx.

Signup and view all the flashcards

Lower Respiratory Tract

Structures including the larynx, trachea, bronchi, bronchioles, and alveoli.

Signup and view all the flashcards

Nasal Cavity Role

The nasal cavity filters air via mucous membranes, humidifies to prevent dryness and warms air with a rich capillary supply.

Signup and view all the flashcards

Alveoli

Gas exchange occurs here, structure is single layer of simple squamous epithelium surrounded by capillaries, featuring a large surface area with a thin diffusion distance.

Signup and view all the flashcards

Diaphragm function in ventilation

Contraction moves downward, expanding the thoracic cavity.

Signup and view all the flashcards

External Intercostals

Elevation of ribs aids in inhalation.

Signup and view all the flashcards

Negative Pressure in Lungs

Leads to air rushing in (inhalation).

Signup and view all the flashcards

Relaxation in Ventilation

Lungs recoil, air exits (exhalation).

Signup and view all the flashcards

Inspiration Mechanism

Active; diaphragm and intercostals contract.

Signup and view all the flashcards

Expiration Mechanism

Passive (at rest); muscles relax, pressure pushes air out.

Signup and view all the flashcards

Tidal Volume (TV)

Normal breath (~500 mL).

Signup and view all the flashcards

Inspiratory Reserve Volume (IRV)

Extra air inhaled after TV.

Signup and view all the flashcards

Expiratory Reserve Volume (ERV)

Extra air exhaled after TV.

Signup and view all the flashcards

Alveolar Exchange - Oxygen

O2 diffuses into capillaries (high → low).

Signup and view all the flashcards

Alveolar Exchange - CO2

CO2 diffuses into alveoli.

Signup and view all the flashcards

Systemic Tissues - Oxygen

O2 exits blood → into cells.

Signup and view all the flashcards

Systemic Tissues - CO2

CO2 produced by cells → enters blood.

Signup and view all the flashcards

Hemoglobin (Hb)

Carries O2 (up to 4 molecules).

Signup and view all the flashcards

Bohr Effect

Low pH = less affinity.

Signup and view all the flashcards

Temperature's Effect on Hemoglobin

Increased temperature decreases affinity.

Signup and view all the flashcards

CO2 Levels Effect on Hemoglobin

Increased CO2 leads to more O2 unloading.

Signup and view all the flashcards

Bicarbonate (HCO3-)

~70% (via carbonic anhydrase reaction).

Signup and view all the flashcards

Medulla Oblongata Function

Sets basic rhythm via inspiratory neurons.

Signup and view all the flashcards

Pons (Apneustic & Pneumotaxic Centers)

Modulate rhythm and depth of breathing.

Signup and view all the flashcards

Peripheral Chemoreceptors

Detect ↓ O2, ↑ CO2, ↓ pH.

Signup and view all the flashcards

Central Chemoreceptors

Sensitive to ↑ CO2 (via H+ in CSF).

Signup and view all the flashcards

Chemoreceptor Signals

Send signals to increase respiratory rate & depth.

Signup and view all the flashcards

Restrictive Lung Disease

Lung expansion is decreased, makes it harder to inhale

Signup and view all the flashcards

Obstructive Lung Disease

Airflow is obstructed, makes it harder to exhale.

Signup and view all the flashcards

Study Notes

  • RESPIRATORY PHYSIOLOGY

Upper vs. Lower Respiratory Tract Structures

  • Upper respiratory tract includes the nose, nasal cavity, sinuses, and pharynx.
  • Lower respiratory tract includes the larynx, trachea, bronchi, bronchioles, and alveoli.

Nasal Cavity Role

  • Conditions air by filtering via mucous membranes, humidifying to prevent dryness, and warming with a rich capillary supply.

Alveoli Function & Structure

  • Function: Site of gas exchange.
  • Structure: Single layer of simple squamous epithelium surrounded by capillaries, providing a large surface area and thin diffusion distance.

Ventilation Mechanics

  • Diaphragm contraction moves it downward, expanding the thoracic cavity.
  • External intercostals elevate ribs.
  • Negative pressure is created, causing air to rush in during inhalation.
  • Relaxation causes lungs to recoil, and air exits during exhalation.

Inspiration vs. Expiration

  • Inspiration: Active; the diaphragm and intercostal muscles contract.
  • Expiration: Passive (at rest); muscles relax, pressure pushes air out.

Lung Volumes

  • Tidal Volume (TV): Normal breath (~500 mL).
  • Inspiratory Reserve Volume (IRV): Extra air inhaled after TV.
  • Expiratory Reserve Volume (ERV): Extra air exhaled after TV.

Gas Exchange at Alveoli & Tissues

  • Alveolar Exchange:
    • O2 diffuses into capillaries (high → low).
    • CO2 diffuses into alveoli.
  • Systemic Tissues:
    • O2 exits blood → into cells.
    • CO2 produced by cells → enters blood.

Hemoglobin & Oxygen

  • Hemoglobin (Hb) carries O2 (up to 4 molecules).
  • Affinity is influenced by:
    • pH (Bohr effect): low pH = less affinity.
    • Temperature: ↑ temp = less affinity.
    • CO2 levels: ↑ CO2 = more O2 unloading.

Carbon Dioxide Transport

  • Form and percentage in blood:
    • Bicarbonate (HCO3-): ~70% (via carbonic anhydrase reaction).
    • Bound to hemoglobin: ~20-23%.
    • Dissolved in plasma: ~7-10%.

Respiratory Control Centers

  • Medulla Oblongata: Sets basic rhythm via inspiratory neurons.
  • Pons (Apneustic & Pneumotaxic Centers): Modulate rhythm and depth of breathing.

Chemoreceptor Regulation

  • Peripheral (carotid & aortic bodies): Detect ↓ O2, ↑ CO2, ↓ pH.
  • Central (medulla): Sensitive to ↑ CO2 (via H+ in CSF).
  • Send signals to increase respiratory rate & depth.

Restrictive vs. Obstructive Lung Diseases

  • Restrictive: Caused by decreased lung expansion (e.g., pulmonary fibrosis, scoliosis).
  • Obstructive: Caused by airflow obstruction (e.g., asthma, COPD, chronic bronchitis, emphysema).

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Blood Components and Their Functions
18 questions
Blood components: Plasma and Formed Elements
30 questions
Use Quizgecko on...
Browser
Browser