Blood Coagulation Pathways Quiz

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Which factor initiates the intrinsic pathway of blood coagulation?

Activation of factor VII.

Contact of blood with injured endothelial collagen tissue. (correct)

Conversion of fibrinogen to fibrin.

Release of tissue factor.

What is the primary function of thrombin in the common coagulation pathway?

To convert prothrombin to fibrinogen.

To activate factor X to Xa.

To release tissue factor from damaged tissue.

To convert fibrinogen to fibrin. (correct)

The extrinsic pathway of coagulation is initiated by which of these?

Conversion of factor IX to IXa.

Contact of blood with collagen.

Release of tissue factor from damaged tissues. (correct)

Activation of factor XI.

What role does factor XIIIa play in the formation of a blood clot?

It stabilizes the fibrin clot. Signup and view all the answers

In both the intrinsic and extrinsic pathways, what factor is ultimately directly activated to convert prothrombin into thrombin?

Factor Xa Signup and view all the answers

Which term refers to a reduction in platelet count?

Thrombocytopenia Signup and view all the answers

What is the primary event during the initial moments of primary hemostasis?

Platelet adhesion to collagen Signup and view all the answers

What does the term 'hemostasis' most accurately describe?

The arrest of bleeding by the body's own mechanisms Signup and view all the answers

In the coagulation process, what is the final substance produced from the conversion of fibrinogen?

Fibrin threads Signup and view all the answers

Which of the following is NOT a condition associated with thrombocytosis?

Acute infections Signup and view all the answers

Which factor is also known as the antihemophilic factor?

Factor VIII Signup and view all the answers

What is the role of tissue factor in secondary hemostasis?

Initiates the extrinsic pathway Signup and view all the answers

In which stage of hemostasis would "bleeding time" be measured?

Primary hemostasis Signup and view all the answers

Which disorder is specifically linked to a structural or functional abnormality of platelets?

Glanzmann thrombasthenia Signup and view all the answers

Which one of the following is NOT a procoagulant, also known as a clotting factor?

Histamine Signup and view all the answers

Which vitamin is essential for the synthesis of prothrombin and other clotting factors?

Vitamin K Signup and view all the answers

What is the primary function of von Willebrand factor (vWF)?

To act as a carrier protein for factor VIII and aid in platelet adhesion Signup and view all the answers

A patient experiences bleeding that continues for 12 minutes after a small cut. What is most likely affected according to the content?

Their bleeding time only Signup and view all the answers

Which of the following best describes hemophilia?

An X-linked congenital disorder leading to deficient clotting factors Signup and view all the answers

Which is a naturally occurring anticoagulant that helps prevent blood clotting within blood vessels?

Heparin Signup and view all the answers

A patient's blood does not have A or B antigens. According to the information, what ABO blood group are they?

Group O Signup and view all the answers

A patient has blood type B. What antibodies are present in their plasma?

Anti-A Signup and view all the answers

A researcher is using a substance to prevent clotting when drawing blood for in vitro tests. Which substance is likely being used?

EDTA Signup and view all the answers