Blood Coagulation Pathways Quiz

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

Which factor initiates the intrinsic pathway of blood coagulation?

  • Activation of factor VII.
  • Contact of blood with injured endothelial collagen tissue. (correct)
  • Conversion of fibrinogen to fibrin.
  • Release of tissue factor.

What is the primary function of thrombin in the common coagulation pathway?

  • To convert prothrombin to fibrinogen.
  • To activate factor X to Xa.
  • To release tissue factor from damaged tissue.
  • To convert fibrinogen to fibrin. (correct)

The extrinsic pathway of coagulation is initiated by which of these?

  • Conversion of factor IX to IXa.
  • Contact of blood with collagen.
  • Release of tissue factor from damaged tissues. (correct)
  • Activation of factor XI.

What role does factor XIIIa play in the formation of a blood clot?

<p>It stabilizes the fibrin clot. (A)</p> Signup and view all the answers

In both the intrinsic and extrinsic pathways, what factor is ultimately directly activated to convert prothrombin into thrombin?

<p>Factor Xa (B)</p> Signup and view all the answers

Which term refers to a reduction in platelet count?

<p>Thrombocytopenia (B)</p> Signup and view all the answers

What is the primary event during the initial moments of primary hemostasis?

<p>Platelet adhesion to collagen (B)</p> Signup and view all the answers

What does the term 'hemostasis' most accurately describe?

<p>The arrest of bleeding by the body's own mechanisms (A)</p> Signup and view all the answers

In the coagulation process, what is the final substance produced from the conversion of fibrinogen?

<p>Fibrin threads (B)</p> Signup and view all the answers

Which of the following is NOT a condition associated with thrombocytosis?

<p>Acute infections (D)</p> Signup and view all the answers

Which factor is also known as the antihemophilic factor?

<p>Factor VIII (D)</p> Signup and view all the answers

What is the role of tissue factor in secondary hemostasis?

<p>Initiates the extrinsic pathway (B)</p> Signup and view all the answers

In which stage of hemostasis would "bleeding time" be measured?

<p>Primary hemostasis (A)</p> Signup and view all the answers

Which disorder is specifically linked to a structural or functional abnormality of platelets?

<p>Glanzmann thrombasthenia (D)</p> Signup and view all the answers

Which one of the following is NOT a procoagulant, also known as a clotting factor?

<p>Histamine (C)</p> Signup and view all the answers

Which vitamin is essential for the synthesis of prothrombin and other clotting factors?

<p>Vitamin K (B)</p> Signup and view all the answers

What is the primary function of von Willebrand factor (vWF)?

<p>To act as a carrier protein for factor VIII and aid in platelet adhesion (D)</p> Signup and view all the answers

A patient experiences bleeding that continues for 12 minutes after a small cut. What is most likely affected according to the content?

<p>Their bleeding time only (C)</p> Signup and view all the answers

Which of the following best describes hemophilia?

<p>An X-linked congenital disorder leading to deficient clotting factors (D)</p> Signup and view all the answers

Which is a naturally occurring anticoagulant that helps prevent blood clotting within blood vessels?

<p>Heparin (D)</p> Signup and view all the answers

A patient's blood does not have A or B antigens. According to the information, what ABO blood group are they?

<p>Group O (B)</p> Signup and view all the answers

A patient has blood type B. What antibodies are present in their plasma?

<p>Anti-A (A)</p> Signup and view all the answers

A researcher is using a substance to prevent clotting when drawing blood for in vitro tests. Which substance is likely being used?

<p>EDTA (C)</p> Signup and view all the answers

Flashcards

Thrombocytopenia

A decrease in the number of platelets in the blood, leading to a condition called thrombocytopenic purpura.

Thrombocytosis

An increase in the number of platelets in the blood. This can occur due to a variety of reasons.

Glanzmann thrombasthenia

A rare inherited bleeding disorder caused by defects in platelet structure or function.

Coagulation

The process by which soluble fibrinogen in the blood is converted into fibrin threads, forming a clot.

Signup and view all the flashcards

Primary Hemostasis

The initial phase of hemostasis where platelets adhere to exposed collagen and form a temporary plug at the site of injury.

Signup and view all the flashcards

Secondary Hemostasis

The second phase of hemostasis where a fibrin network is laid down to strengthen the platelet plug, forming a definitive clot.

Signup and view all the flashcards

Intrinsic Pathway

The pathway of coagulation triggered by factors within the blood itself.

Signup and view all the flashcards

Extrinsic Pathway

The pathway of coagulation triggered by the release of tissue factor from injured tissues.

Signup and view all the flashcards

Common Pathway

The final common pathway of coagulation where both the intrinsic and extrinsic pathways converge.

Signup and view all the flashcards

Hemostasis

The process by which bleeding is stopped through a series of physiological processes.

Signup and view all the flashcards

Fibrin

A protein that forms thread-like structures to trap blood cells and platelets, creating a stable clot.

Signup and view all the flashcards

What is von Willebrand factor (vWF)?

A large glycoprotein synthesized by endothelial cells and platelets that acts as a carrier protein for factor VIII and helps platelets adhere to injured vessels.

Signup and view all the flashcards

What is Clotting Time?

The time from the start of bleeding until the formation of a firm clot, typically lasting between 2-10 minutes.

Signup and view all the flashcards

What are anticoagulants?

Substances that prevent blood clotting. They can be natural or synthetic.

Signup and view all the flashcards

What is Hemophilia?

A congenital bleeding disorder caused by a deficiency in either factor VIII (Hemophilia A) or factor IX (Hemophilia B). Minor injuries can lead to prolonged bleeding.

Signup and view all the flashcards

What is coagulation?

The process by which soluble fibrinogen in the blood is converted into fibrin threads, forming a clot.

Signup and view all the flashcards

What is Bleeding Time?

The time from the start of bleeding until the formation of a platelet plug, usually lasting within 2-8 minutes.

Signup and view all the flashcards

What is the liver's role in coagulation?

Liver plays a critical role in the production of several clotting factors, including prothrombin, proconvertin, fibrinogen, factors V, VII, IX, X, and antihemophilic globulin. Liver failure can lead to severe coagulation disorders.

Signup and view all the flashcards

What is the role of Vitamin K in coagulation?

Vitamin K is essential for the synthesis of prothrombin and other clotting factors. Deficiency in Vitamin K can lead to increased bleeding.

Signup and view all the flashcards

More Like This

Use Quizgecko on...
Browser
Open
Browser
Browser