Blood Cells

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What is the normal range of red blood cells (RBC) in men?

4.2-6.1 x 10^6/mcl

What is the primary responsibility of erythrocytes (RBC)?

Carrying and transporting oxygen

What is the molecule responsible for carrying gases and electrolytes in erythrocytes (RBC)?

Hemoglobin

What percentage of total body iron is stored in macrophages?

<p>About 30%</p> Signup and view all the answers

What is the life cycle of erythrocytes (RBC) primarily limited by?

<p>Inability to go through mitosis</p> Signup and view all the answers

What is the primary function of heme in red blood cells?

<p>Carrying oxygen</p> Signup and view all the answers

Which molecule is involved in protecting red blood cells against oxidative stress?

<p>G6PD</p> Signup and view all the answers

What regulates the balance between production and destruction of red blood cells?

<p>Erythropoietin</p> Signup and view all the answers

What happens to the heme and globin when old red blood cells are destroyed?

<p>The heme is metabolized into bilirubin, while globin is broken down into amino acids</p> Signup and view all the answers

What is the major iron storage protein?

<p>Ferritin</p> Signup and view all the answers

What carries iron for hemoglobin production to the bone marrow?

<p>Transferrin</p> Signup and view all the answers

Which enzyme deficiency can result in damage and death to red blood cells?

<p>Pyruvate kinase</p> Signup and view all the answers

What is the normal range for hemoglobin in grams per deciliter?

<p>12-18 g/dL</p> Signup and view all the answers

What is the primary role of the biconcavity and reversible deformity of erythrocytes (RBC)?

<p>To optimize surface area for gas diffusion</p> Signup and view all the answers

Which molecule competitively binds to heme in red blood cells with an affinity 200-300 times greater than oxygen?

<p>Carbon monoxide (CO)</p> Signup and view all the answers

What is the main energy source for red blood cells, given their lack of mitochondria?

<p>Glycolysis</p> Signup and view all the answers

Which enzyme deficiency can lead to damage and death of red blood cells?

<p>Glucose-6-phosphate dehydrogenase (G6PD) deficiency</p> Signup and view all the answers

What is the primary function of transferrin in the bloodstream?

<p>Carries iron for hemoglobin production to the bone marrow</p> Signup and view all the answers

What is the primary function of ferritin in iron metabolism?

<p>Store excess iron in macrophages</p> Signup and view all the answers

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