Blood Banking and Component Therapy Quiz
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Questions and Answers

What is the temperature range required for the transport of RBCs?

  • 1-10°C (correct)
  • 30-35°C
  • 15-20°C
  • 25-30°C

    • ABO/Rh typing detects A, B, and D antigens using patient's RBCs and reagent RBCs.

    True

    ABO/Rh typing detects A, B, and D antigens using patient's RBCs and reagent RBCs.

    True

    What is the purpose of ABO/Rh typing?

    <p>To detect A, B, and D antigens in patient's RBCs and reagent RBCs</p> Signup and view all the answers

    What is the purpose of ABO/Rh typing?

    <p>To detect specific antigens in the patient's RBCs</p> Signup and view all the answers

    What is the purpose of antibody identification?

    <p>To identify antibodies to RBC antigens</p> Signup and view all the answers

    Antibodies are detected using reagent anti-A, anti-B, and anti-D or patient's serum.

    <p>True</p> Signup and view all the answers

    Which blood component is used to control or prevent bleeding?

    <p>Platelets</p> Signup and view all the answers

    What is the purpose of antibody screen?

    <p>To detect antibodies to BC antigens using reagent antibody screening cells and patient's serum</p> Signup and view all the answers

    Antibodies are detected using reagent anti-A, anti-B, and anti-D or patient's serum.

    <p>True</p> Signup and view all the answers

    Antibody screen detects specific antibodies to BC antigens using reagent antibody screening cells and patient's serum.

    <p>False</p> Signup and view all the answers

    What is the purpose of the crossmatch?

    <p>To determine the compatibility of donor RBCs with the recipient's blood</p> Signup and view all the answers

    Antibody screen detects specific antibodies to BC antigens using reagent antibody screening cells and patient's serum.

    <p>False</p> Signup and view all the answers

    What is the purpose of antibody identification?

    <p>To identify antibodies to RBC antigens</p> Signup and view all the answers

    What is the expiration date of deglycerolized RBCs?

    <p>24 hours</p> Signup and view all the answers

    What is the purpose of crossmatch?

    <p>To determine compatibility of donor RBCs with recipient's blood</p> Signup and view all the answers

    What types of reagents are used in blood banking?

    <p>Antisera, antiglobulin reagents, and potentiators</p> Signup and view all the answers

    What is the purpose of leukocyte-reduced RBCs?

    <p>To prevent febrile transfusion reactions</p> Signup and view all the answers

    Antibody identification identifies antibodies to RBC antigens using reagent antibody panel cells and patient's serum.

    <p>True</p> Signup and view all the answers

    Antibody identification identifies antibodies to RBC antigens using reagent antibody panel cells and patient's serum.

    <p>True</p> Signup and view all the answers

    What is the purpose of irradiated RBCs?

    <p>To prevent T cell proliferation</p> Signup and view all the answers

    What is the purpose of ABO antisera?

    <p>To detect specific antigens in the patient's RBCs</p> Signup and view all the answers

    Crossmatch determines compatibility of donor RBCs with recipient's blood using donor cells and recipient's serum.

    <p>True</p> Signup and view all the answers

    What is the purpose of ABO antisera?

    <p>To determine patient's blood type</p> Signup and view all the answers

    Crossmatch determines compatibility of donor RBCs with recipient's blood using donor cells and recipient's serum.

    <p>True</p> Signup and view all the answers

    Blood bank reagents are not regulated by the FDA.

    <p>False</p> Signup and view all the answers

    What is the purpose of D typing?

    <p>To prevent HTR and HDN</p> Signup and view all the answers

    Blood bank reagents are not licensed by FDA.

    <p>False</p> Signup and view all the answers

    What is the purpose of D typing?

    <p>To detect specific antigens in the patient's RBCs</p> Signup and view all the answers

    What is the temperature range required for the storage of frozen RBCs?

    <p>-65°C</p> Signup and view all the answers

    What is the purpose of donor selection?

    <p>To ensure the safety of donated blood</p> Signup and view all the answers

    What is the purpose of leukocyte-reduced RBCs?

    <p>To be used in chronically transfused patients or patients having known febrile transfusion reactions</p> Signup and view all the answers

    What is the main purpose of fresh-frozen plasma?

    <p>To replace coagulation factors in the patient</p> Signup and view all the answers

    ABO antisera are used to determine patient's blood type, and anti-A and anti-B reagents are colored with blue and yellow dye, respectively.

    <p>True</p> Signup and view all the answers

    Two types of reagents used for D typing are high protein and low-protein polyclonal.

    <p>False</p> Signup and view all the answers

    What is the shelf life of platelets?

    <p>3 to 4 days</p> Signup and view all the answers

    D typing detects important antigens to prevent HTR and HDN using only high protein monoclonal reagents.

    <p>False</p> Signup and view all the answers

    What is the purpose of frozen RBCs?

    <p>To be stored at -65°C for 10 years</p> Signup and view all the answers

    What is the purpose of autologous donation?

    <p>To collect and store a patient's own blood for future use</p> Signup and view all the answers

    Donor selection involves only registration questions and educational material.

    <p>False</p> Signup and view all the answers

    Frozen RBCs are frozen by adding glucose to prevent cell hydration and the formation of ice crystals.

    <p>False</p> Signup and view all the answers

    What is the purpose of leukocyte-reduced RBCs?

    <p>To reduce the risk of febrile transfusion reactions</p> Signup and view all the answers

    What is the purpose of washed RBCs?

    <p>To be used for patients who have a reaction to plasma proteins</p> Signup and view all the answers

    Donor selection involves registration questions, educational material, physical exam, and confidential unit exclusion.

    <p>True</p> Signup and view all the answers

    What is the process of washing RBCs with normal saline called?

    <p>Washing</p> Signup and view all the answers

    Washed RBCs are used for patients who have a reaction to plasma proteins and do not result in any loss of RBCs.

    <p>False</p> Signup and view all the answers

    Frozen RBCs are stored at -80°C for 10 years.

    <p>False</p> Signup and view all the answers

    Which blood component is used in patients requiring exchange transfusions?

    <p>Whole blood</p> Signup and view all the answers

    What is the purpose of irradiated RBCs?

    <p>To prevent T cell proliferation and are required for cellular components if a donor is a blood relative of the intended recipient or donor unit is HLA matched for the recipient</p> Signup and view all the answers

    What is the purpose of irradiated RBCs?

    <p>To prevent T cell proliferation</p> Signup and view all the answers

    Washed RBCs are used for patients who have a reaction to plasma proteins and no RBCs are lost in the process.

    <p>False</p> Signup and view all the answers

    What is the purpose of fresh-frozen plasma?

    <p>To replace coagulation factors in the patient</p> Signup and view all the answers

    Platelets are used to prevent bleeding and have a life span of 3 to 4 days.

    <p>True</p> Signup and view all the answers

    What is the purpose of D typing?

    <p>To detect important antigens to prevent HTR and HDN</p> Signup and view all the answers

    What is the purpose of fresh-frozen plasma?

    <p>To replace coagulation factors in the patient</p> Signup and view all the answers

    Fresh-Frozen Plasma is used to replace coagulation factors in the patient and is indicated in patients with fibrinogen >100 mg/dL.

    <p>False</p> Signup and view all the answers

    What is the recommended storage temperature for RBCs during transport?

    <p>1-10°C</p> Signup and view all the answers

    Fresh-Frozen Plasma is used to replace coagulation factors in the patient and is indicated in bleeding patients who require factors I, IV, V, VIII, and XII.

    <p>False</p> Signup and view all the answers

    What is the storage temperature for RBCs during transport?

    <p>1-10°C</p> Signup and view all the answers

    What is the purpose of the antibody screen test?

    <p>To detect specific antibodies to BC antigens</p> Signup and view all the answers

    Study Notes

    Blood Banking: Summary of Key Points

    • ABO/Rh typing detects A, B, and D antigens using patient's RBCs and reagent RBCs. Antibodies are detected using reagent anti-A, anti-B, and anti-D or patient's serum.
    • Antibody screen detects specific antibodies to BC antigens using reagent antibody screening cells and patient's serum.
    • Antibody identification identifies antibodies to RBC antigens using reagent antibody panel cells and patient's serum.
    • Crossmatch determines compatibility of donor RBCs with recipient's blood using donor cells and recipient's serum.
    • Blood bank reagents are licensed by FDA and must meet potency and specificity standards.
    • Types of reagents include reagent RBCs, antisera, antiglobulin reagents, and potentiators.
    • ABO antisera are used to determine patient's blood type, and anti-A and anti-B reagents are colored with blue and yellow dye, respectively.
    • D typing detects important antigens to prevent HTR and HDN. Two types of reagents are high protein and low-protein monoclonal.
    • Donor selection involves registration questions, educational material, physical exam, and confidential unit exclusion.
    • Autologous donation includes preoperative, intraoperative hemodilution, intraoperative collection, and postoperative collection.
    • Hemotherapy uses blood or blood components to treat a disease in a patient.
    • Blood components include whole blood, RBCs, plasma, platelets, and cryoprecipitated antihemophiliac factor. They have different storage temperatures and expiration dates.Blood Component Storage, Transportation, and Therapy

    Storage and Transportation:

    • FDA requirements and AABB Standards define calibration, maintenance, and monitoring procedures for equipment used to store blood products.
    • All refrigerators, freezers, and platelet incubators must have recording devices, audible alarms, regular alarm checks, power failure, and alarm activation emergency procedures, emergency power backups, calibrated thermometers, and written procedures.
    • RBCs require a temperature of 1-10°C during transport and are packed in cardboard boxes with a styrofoam box inside, with a predetermined amount of wet ice in plastic bags placed on top of the blood units to maintain the temperature for 24 hours.
    • Frozen components are shipped on dry ice, and platelets are shipped at room temperature.
    • When component shipments are received, the temperature and appearance of units must be observed and recorded, and any out-of-range temperatures require evaluation before transfusion.

    Blood Component Therapy:

    • Whole blood is used in actively bleeding patients, patients who have lost at least 25% of their blood volume, or patients requiring exchange transfusions.
    • RBCs are used in oncology patients undergoing chemotherapy or radiation therapy, trauma patients, surgery patients, dialysis patients, premature infants, and patients with sickle cell anemia. One unit usually increases the patient's hemoglobin approximately 1 g/dL and the hematocrit by 3%.
    • Leukocyte-reduced RBCs are used in chronically transfused patients or patients having known febrile transfusion reactions. A special filter is required for bedside filtration, and leukoreduction can also occur in the manufacturing process.
    • Frozen RBCs are frozen by adding glycerol to prevent cell hydration and the formation of ice crystals that can cause cell lysis. They are stored at -65°C for 10 years.
    • Deglycerolized RBCs are thawed, and then the glycerol must be removed by washing the RBCs with a series of saline solutions of decreasing osmolality. They expire in 24 hours.
    • Washed RBCs are used for patients who have a reaction to plasma proteins (allergic, febrile, and/or anaphylactic) and in infant or intrauterine transfusions. 10-20% of RBCs are lost in the process of washing the RBC unit with normal saline.
    • Irradiated RBCs prevent T cell proliferation and are required for cellular components if a donor is a blood relative of the intended recipient or donor unit is HLA matched for the recipient.
    • Platelets are used to control or prevent bleeding and have a life span of 3 to 4 days. They can be prepared from a whole blood unit or pooled from bags. Plateletpheresis packs contain approximately 3 X 10^11 platelets per unit.
    • Fresh-Frozen Plasma is used to replace coagulation factors in the patient and is indicated in bleeding patients who require factors II, V, VII, IX, and X, abnormal coagulation due to massive transfusion, patients on anticoagulants who are bleeding or require surgery, treatment of TTP and hemolytic uremic syndrome, patients with liver disease to prevent or correct bleeding, antithrombin III deficiencies, and DIC when fibrinogen is >100 mg/dL. It should be thawed in a water bath at 30-37°C for

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    Description

    Think you know everything there is to know about blood banking and blood component therapy? Test your knowledge with our comprehensive quiz! From ABO/Rh typing to blood component storage and transportation, this quiz covers all the key points you need to know. Perfect for medical students, healthcare professionals, and anyone interested in learning more about this vital field. Don't wait, take the quiz now and see how well you do!

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