Questions and Answers
What is the main reason for donor screening?
What is the main reason for donor screening?
Which blood group system includes high and low incidence antigens?
Which blood group system includes antigens carried by the integral membrane protein AQP1 in the kidneys?
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Which blood group system includes high and low incidence antigens?
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Which blood group system includes antigens carried by the integral membrane protein AQP1 in the kidneys?
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What does the donor screening process identify?
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What does the donor screening process identify?
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Which antigen is carried by the integral membrane protein AQP1 in the kidneys?
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Which antibodies are associated with moderate transfusion reactions?
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Which antibodies are associated with moderate transfusion reactions?
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Which antigen is carried by the integral membrane protein AQP1 in the kidneys?
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Which of the following is NOT a type of blood donor?
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Which antibody is associated with severe HDFN?
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Which antigen is carried by intracellular adhesion molecule 4?
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Which antibody is associated with severe HDFN?
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Which antigen is carried by intracellular adhesion molecule 4?
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Which of the following is NOT a type of blood donor?
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What information is included in donor registration?
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Which antigen is carried by intracellular adhesion molecule 4?
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Which antigen is carried by intracellular adhesion molecule 4?
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What information is included in donor registration?
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Which antibody is associated with severe HDFN?
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Which antibody is associated with severe HDFN?
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Which antibody agglutinates Rh(+) and Rh(-) cells except Rhnull?
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Which blood group system includes low-incidence antigens with an incidence of less than 1%?
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What are the basic qualifications of a potential donor?
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Which blood group system includes low-incidence antigens with an incidence of less than 1%?
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Which antibody agglutinates Rh(+) and Rh(-) cells except Rhnull?
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What are the basic qualifications of a potential donor?
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Which antibodies are implicated in transfusion reactions?
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What criteria are used for whole blood donors?
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What criteria are used for whole blood donors?
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Which antibodies are implicated in transfusion reactions?
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Which antigens have an incidence of less than 1%?
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Which antigens have an incidence of less than 1%?
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What is autologous transfusion?
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Which type of antibodies exhibit weak agglutination at any dilution?
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Which blood group system includes Chido/Rodgers antigens associated with the HLA system?
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Which type of antibodies exhibit weak agglutination at any dilution?
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Which blood group system includes Chido/Rodgers antigens associated with the HLA system?
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What is autologous transfusion?
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Which phenotype presents with elliptocytosis?
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Which blood group antigen is associated with neonatal alloimmune neutropenia and post-transfusion purpura?
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Which blood group antigen is associated with neonatal alloimmune neutropenia and post-transfusion purpura?
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What methods are used for HGB determination?
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Which phenotype presents with elliptocytosis?
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What methods are used for HGB determination?
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Which antibodies exhibit weak agglutination at any dilution?
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Which blood group system includes Triantigens?
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What replaced the Blood Banking Law of 1956?
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Which blood group system includes Triantigens?
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Which antibodies exhibit weak agglutination at any dilution?
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What replaced the Blood Banking Law of 1956?
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Which blood group antigens include granulocyte antigens and human neutrophil antigens (HNA) and human platelet antigens (HPA)?
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Which type of antibodies are not detected with enzyme treatment?
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Which donors are deferred?
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Which donors are deferred?
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Which blood group antigens include granulocyte antigens and human neutrophil antigens (HNA) and human platelet antigens (HPA)?
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Which type of antibodies are not detected with enzyme treatment?
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Which antibodies are not detected with enzyme treatment?
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Which antibodies are not detected with enzyme treatment?
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Which blood group antigen is associated with elliptocytosis?
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Which blood group antigen is associated with elliptocytosis?
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What is the clinical significance of HPA?
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What is the clinical significance of HPA?
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Which blood group antigen is associated with the HLA system?
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Which blood group antigen is associated with the HLA system?
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Study Notes
- Co antigens are carried by the integral membrane protein AQP1 in the kidneys
- Anti-Coa and anti-Cob are associated with moderate transfusion reactions
- Anti-CO3 is associated with severe HDFN
- LW antigen is carried by intracellular adhesion molecule 4
- Anti-LW agglutinates Rh(+) and Rh(-) cells except Rhnull
- Chido/Rodgers antigens are associated with the HLA system
- Gerbich phenotype includes high and low incidence antigens
- Leach phenotype presents with elliptocytosis
- Anti-Ge2 and anti-Ge3 are implicated in transfusion reactions
- Natural occurring IgG immunoglobulins and autoantibodies are associated with transfusion reactions.
- There are several blood group systems, including Augustine, Gregory, Langereis, Cromer, Holley, Oka, Ena, Jacobs, VEL, Gerbich, and Joseph.
- Low-incidence antigens have an incidence of less than 1% and include the Wright blood group system, Swann, By, Mta, and Triantigens.
- High-titer, low-avidity (HTLA) antibodies are clinically benign and exhibit weak agglutination at any dilution.
- Antibodies formed are classified as HTLAs due to similar serologic reactivity, but some may be significant.
- Antigens such as Anti-Cha, Anti-JMH, Anti-McCa, Anti-Rga, Anti-Yka, Anti-Kn, and Anti-Cs have different antibody characteristics.
- Antibody characteristics include clinically significant or insignificant, naturally occurring, warm or cold antibodies, and can react in any phase of testing.
- Detection is enhanced by enzyme treatment of test cells, while some antibodies are not detected with enzyme treatment.
- Other blood group antigens include granulocyte antigens and human neutrophil antigens (HNA) and human platelet antigens (HPA).
- Clinical significance of HPA includes neonatal alloimmune neutropenia, autoimmune neutropenia, and post-transfusion purpura.
- Clinical significance of HPA includes neonatal alloimmune thrombocytopenia and post-transfusion purpura.
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Description
Test your knowledge of blood antigens and antibodies with this quiz! From Co antigens to Gerbich phenotypes, this quiz covers a variety of topics related to blood group systems. Learn about the clinical significance of HTLA antibodies, the characteristics of different blood group antigens, and the detection methods used to identify them. You'll also explore other blood group antigens and their clinical significance, including HNA and HPA. Challenge yourself and see how much you know about blood antigens and antibodies