Blood and Hematopoiesis Overview

White blood cells responsible for cell-mediated immunity, originating in the thymus.

White blood cells that give rise to plasma cells after diapedesis, providing humoral immunity, originating in the bone marrow (mammals) or Bursa of Fabricius (birds).

A type of lymphocyte responsible for killing virus-infected cells and tumor cells by direct cell-mediated cytotoxicity.

Large white blood cells with an oval, kidney-shaped, or horseshoe-shaped nucleus. Their cytoplasm is basophilic and contains vacuoles (lysosomes).

Derived from monocytes, these cells are phagocytic, meaning they engulf and destroy foreign material. They also present antigens to T cells and secrete stimulating factors.

A type of white blood cell that plays a crucial role in the immune response. They differentiate into plasma cells and produce antibodies. They originate in the bone marrow.

Tumors arising from mast cells, often found in dogs and cats, with varying degrees of malignancy.

A type of white blood cell that is responsible for recognizing and destroying foreign cells and pathogens through the production of antibodies.

Specialized cells that reside in different tissues, responsible for engulfing and breaking down foreign material and cellular debris.

Specialized histiocytes found in the liver, involved in filtering blood and removing old blood cells.

Giant multinucleated cells in bone, responsible for breaking down old bone tissue during bone remodeling.

Large cells found in cartilage that break down cartilage tissue.

Macrophages found in the air sacs of the lungs, responsible for engulfing inhaled particles and debris.

Special type of immune cells found in the skin, responsible for presenting antigens to other immune cells.

Special cells found in the kidney, important for filtering and cleaning blood.

Immune cells found in the brain, responsible for removing debris and responding to infections.

Small, disc-shaped, anucleated cell fragments that play a vital role in blood clotting.

Large, multinucleated bone marrow cells that produce platelets through fragmentation.

A type of white blood cell that plays a role in fighting parasitic infections and allergic reactions. They are characterized by their bilobed nucleus and eosinophilic granules.

A type of white blood cell that releases histamine and other chemicals to trigger inflammatory responses. They are involved in allergies, asthma, and other immune reactions.

A type of cell found in tissues that releases histamine and other substances involved in allergic reactions and inflammation. They are important for triggering immune responses at specific sites.

A severe systemic reaction to allergens, characterized by widespread mast cell degranulation, vasodilation, and shock.

A condition characterized by the overproduction of mast cells, which can lead to skin lesions or involvement of multiple organs.

A type of immune response that involves the body's own immune system attacking its own tissues. It can affect various organs and lead to inflammation and damage.

A type of allergy that affects the skin and mucous membranes, often involving mast cells.

A type of inflammatory condition that affects the joints. Mast cells are involved in recruiting inflammatory cells to the joints.

Fluid connective tissue responsible for transporting oxygen, nutrients, and removing waste products.

The liquid component of blood that contains dissolved substances, proteins, and other factors.

The cellular components of blood including red blood cells, white blood cells, and platelets.

Red blood cells, responsible for transporting oxygen to tissues throughout the body.

Anucleated, biconcave, disk-shaped cells with a large surface area for optimal gas exchange.

The protein in red blood cells that binds oxygen and carbon dioxide, responsible for oxygen transport.

White blood cells, responsible for defending the body against infections and foreign invaders.

White blood cells with multi-lobed nuclei, containing specific granules.

White blood cells with round or kidney-shaped nuclei, containing azurophilic granules.

The most abundant type of white blood cell, responsible for engulfing and destroying bacteria.

A type of white blood cell that helps fight parasitic infections and allergic reactions.

A type of white blood cell that releases histamine and other chemicals involved in inflammation and allergic reactions.

Small, cell fragments responsible for blood clotting (hemostasis).

The process of blood cell formation, mainly focusing on red blood cells (erythropoiesis) and white blood cells (granulocytopoiesis), which shifts from the liver and spleen to the bone marrow during late fetal development.

This stage marks the primary center of blood formation in young individuals, where the long bones, ribs, vertebrae, pelvis, skull, and sternum play a key role.

As people age, bone marrow activity decreases, and the central marrow of long bones converts from red marrow (active in blood cell production) to yellow marrow, which stores fat.

The soft tissue found inside bones, responsible for producing various blood cells.

A type of bone marrow that is actively involved in the production of all blood cells.

A type of bone marrow that primarily stores fat, with limited blood cell production.

These are the blood vessels within bone marrow that carry blood cells into circulation.

These cells are developing red blood cells, going through various stages of maturation in the bone marrow.

These cells are developing white blood cells, also known as leukocytes, going through different phases of maturation in the bone marrow.

The process of blood cell formation, occurring in the bone marrow, where stem cells differentiate into various blood components.

A procedure where a sample of bone marrow is extracted, typically from the pelvic bone, for diagnosis and treatment of blood disorders.

A treatment for certain blood disorders, involving the transplantation of healthy bone marrow cells from a donor to a recipient.

Red blood cells, responsible for carrying oxygen throughout the body.

White blood cells, playing a crucial role in the immune system, protecting the body from infections and diseases.

Platelets, essential for blood clotting and wound healing by forming clots to stop bleeding.