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Bleeding and Coagulation Disorders Quiz

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Questions and Answers

What is the initial therapy for milder cases of ITP?

RITUXIMAB

Rho(d) Immunoglobulin (correct)

Thrombopoietin receptor agonists

Splenectomy

Which feature is a common characteristic of inherited thrombocytopenia disorders?

Small platelets

Large platelets (correct)

Normal platelet size

Decreased number of platelets

What is a classic pentad associated with Thrombotic Thrombocytopenic Purpura (TTP)?

Hypertension, Fatigue, Edema, Nausea, Itching

Microangiopathic hemolytic anemia, Thrombocytopenia, Renal involvement, Neurologic signs, Fever (correct)

Shortness of breath, Dizziness, Chest pain, Palpitations, Cough

Weight loss, Insomnia, Joint pain, Constipation, Headache

What enzyme deficiency results in Upshaw-Schulman syndrome (congenital TTP)?

ADAMTS13 (B) Signup and view all the answers

Which test result supports the diagnosis of TTP?

Negative direct antiglobulin test (D) Signup and view all the answers

What remains the mainstay of treatment for TTP?

Plasma exchange (D) Signup and view all the answers

Extbf{Symptoms} of Thrombotic Thrombocytopenic Purpura (TTP) include:

<pre><code>extbf{Neurologic} signs (C) </code></pre> Signup and view all the answers