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Questions and Answers
What is the cytoskeleton?
What is the cytoskeleton?
A network of protein filaments extending throughout the cytoplasm of eukaryotic cells.
What are the three main types of protein filaments that make up the cytoskeleton?
What are the three main types of protein filaments that make up the cytoskeleton?
The cytoskeleton is rigid and does not change shape.
The cytoskeleton is rigid and does not change shape.
False
What is the primary role of actin filaments in the cytoskeleton?
What is the primary role of actin filaments in the cytoskeleton?
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What is the diameter of actin filaments?
What is the diameter of actin filaments?
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What are the two main types of actin-binding proteins?
What are the two main types of actin-binding proteins?
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What are the two main types of actin bundles?
What are the two main types of actin bundles?
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Why are red blood cells useful for studying the cortical cytoskeleton?
Why are red blood cells useful for studying the cortical cytoskeleton?
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What is the function of spectrin in the red blood cell cytoskeleton?
What is the function of spectrin in the red blood cell cytoskeleton?
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What is the function of ankyrin in the red blood cell cytoskeleton?
What is the function of ankyrin in the red blood cell cytoskeleton?
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What is the function of protein 4.1 in the red blood cell cytoskeleton?
What is the function of protein 4.1 in the red blood cell cytoskeleton?
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What is the function of dystrophin in muscle cells?
What is the function of dystrophin in muscle cells?
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Patients with muscular dystrophy have an increase in dystrophin levels.
Patients with muscular dystrophy have an increase in dystrophin levels.
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What are stress fibers?
What are stress fibers?
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What are focal adhesions?
What are focal adhesions?
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What are adherens junctions?
What are adherens junctions?
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What are microvilli?
What are microvilli?
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What is the brush border?
What is the brush border?
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What is the function of myosin I in microvilli?
What is the function of myosin I in microvilli?
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What are pseudopodia?
What are pseudopodia?
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What are lamellipodia?
What are lamellipodia?
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What are filopodia?
What are filopodia?
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What are the three stages of cell movement across a surface?
What are the three stages of cell movement across a surface?
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What is the role of Rho proteins in cell movement?
What is the role of Rho proteins in cell movement?
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How do Rho proteins activate the formation of branched actin filaments?
How do Rho proteins activate the formation of branched actin filaments?
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What is the role of microtubules in the cytoskeleton?
What is the role of microtubules in the cytoskeleton?
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What are the subunits of microtubules?
What are the subunits of microtubules?
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Microtubules are non-polar structures.
Microtubules are non-polar structures.
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What is the function of gamma-tubulin in microtubule assembly?
What is the function of gamma-tubulin in microtubule assembly?
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What is dynamic instability?
What is dynamic instability?
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The plus end of a microtubule is the end that is typically stabilized.
The plus end of a microtubule is the end that is typically stabilized.
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What is the function of colchicine and colcemid?
What is the function of colchicine and colcemid?
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What is the function of vincristine and vinblastine?
What is the function of vincristine and vinblastine?
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What is the function of taxol in microtubule dynamics?
What is the function of taxol in microtubule dynamics?
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What are microtubule-associated proteins (MAPs)?
What are microtubule-associated proteins (MAPs)?
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What is the function of polymerase MAPs?
What is the function of polymerase MAPs?
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What is the function of depolymerase MAPs?
What is the function of depolymerase MAPs?
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What is the function of CLASP proteins?
What is the function of CLASP proteins?
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What is the centrosome?
What is the centrosome?
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What is the mitotic spindle?
What is the mitotic spindle?
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How do plant cells differ from animal cells in terms of microtubule organization?
How do plant cells differ from animal cells in terms of microtubule organization?
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What is the function of the gamma-tubulin ring complex?
What is the function of the gamma-tubulin ring complex?
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What are centrioles?
What are centrioles?
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What are the two families of motor proteins responsible for microtubule-based movements?
What are the two families of motor proteins responsible for microtubule-based movements?
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What is the direction of movement for kinesins along microtubules?
What is the direction of movement for kinesins along microtubules?
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What is the direction of movement for dyneins along microtubules?
What is the direction of movement for dyneins along microtubules?
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Axonemal dynein was the first identified microtubule motor protein due to its abundance in cilia.
Axonemal dynein was the first identified microtubule motor protein due to its abundance in cilia.
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What is the function of cytoplasmic dynein?
What is the function of cytoplasmic dynein?
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What is the main function of microtubules in the cell?
What is the main function of microtubules in the cell?
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Kinesins and dyneins always transport cargo in the same direction.
Kinesins and dyneins always transport cargo in the same direction.
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Microtubules can help position organelles within the cell.
Microtubules can help position organelles within the cell.
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What is the role of cytoplasmic dynein in relation to the Golgi apparatus?
What is the role of cytoplasmic dynein in relation to the Golgi apparatus?
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What are cilia and flagella?
What are cilia and flagella?
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Both cilia and flagella have the same structure, referred to as the axoneme.
Both cilia and flagella have the same structure, referred to as the axoneme.
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What is the function of nexin in the axoneme?
What is the function of nexin in the axoneme?
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Dynein arms in the axoneme are attached to the B tubule of each doublet.
Dynein arms in the axoneme are attached to the B tubule of each doublet.
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What is the function of the basal body?
What is the function of the basal body?
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The movement of cilia and flagella is powered by the sliding of outer microtubule doublets relative to one another.
The movement of cilia and flagella is powered by the sliding of outer microtubule doublets relative to one another.
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How does the mitotic spindle form?
How does the mitotic spindle form?
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What are the different types of microtubules that make up the mitotic spindle?
What are the different types of microtubules that make up the mitotic spindle?
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What is the function of kinetochore microtubules in mitosis?
What is the function of kinetochore microtubules in mitosis?
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What is the function of chromosomal microtubules in mitosis?
What is the function of chromosomal microtubules in mitosis?
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What is the function of polar microtubules in mitosis?
What is the function of polar microtubules in mitosis?
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What is the function of astral microtubules in mitosis?
What is the function of astral microtubules in mitosis?
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What is the function of chromokinesin?
What is the function of chromokinesin?
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What are the two steps of chromosome movement in anaphase?
What are the two steps of chromosome movement in anaphase?
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What is the function of kinesins in Anaphase A?
What is the function of kinesins in Anaphase A?
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What is the function of plus-end-directed kinesins in Anaphase B?
What is the function of plus-end-directed kinesins in Anaphase B?
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What is the function of cytoplasmic dynein in Anaphase B?
What is the function of cytoplasmic dynein in Anaphase B?
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What are intermediate filaments?
What are intermediate filaments?
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Intermediate filaments are directly involved in cell movement.
Intermediate filaments are directly involved in cell movement.
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What are the main types of intermediate filaments?
What are the main types of intermediate filaments?
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What is the function of keratins?
What is the function of keratins?
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What is the function of vimentin?
What is the function of vimentin?
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What is the function of desmin?
What is the function of desmin?
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What is the function of neurofilament proteins?
What is the function of neurofilament proteins?
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What is the function of nuclear lamins?
What is the function of nuclear lamins?
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Intermediate filaments have distinct ends, similar to actin filaments and microtubules.
Intermediate filaments have distinct ends, similar to actin filaments and microtubules.
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Intermediate filaments are more stable than actin filaments and microtubules.
Intermediate filaments are more stable than actin filaments and microtubules.
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What is the function of the central rod domain in intermediate filament assembly?
What is the function of the central rod domain in intermediate filament assembly?
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What is the function of the head and tail domains in intermediate filaments?
What is the function of the head and tail domains in intermediate filaments?
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Intermediate filaments can associate with other cytoskeleton elements.
Intermediate filaments can associate with other cytoskeleton elements.
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What are desmosomes?
What are desmosomes?
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What is the function of desmoplakin?
What is the function of desmoplakin?
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What are hemidesmosomes?
What are hemidesmosomes?
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What is the function of plectin?
What is the function of plectin?
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Experimental evidence for the function of intermediate filaments is highly established and has been available for many years.
Experimental evidence for the function of intermediate filaments is highly established and has been available for many years.
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What is Epidermolysis bullosa simplex (EBS)?
What is Epidermolysis bullosa simplex (EBS)?
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