Biotin: Functions and Properties

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Questions and Answers

Which biochemical role does biotin fulfill in carboxylation reactions?

  • It acts as an allosteric inhibitor.
  • It acts as a reducing agent.
  • It catalyzes the hydrolysis of peptide bonds.
  • It serves as a carrier of activated carbon dioxide. (correct)

How is biotin typically bound to biotin-dependent enzymes?

  • Through ionic interactions.
  • Covalently to the ε-amino groups of lysine residues. (correct)
  • Via hydrogen bonds.
  • Through disulfide bridges.

Why does biotin deficiency not occur naturally in humans?

  • It is widely distributed in food and supplied by intestinal bacteria. (correct)
  • Biotin is absorbed through the skin from the environment.
  • Biotin is stored in large quantities in human adipose tissue.
  • Because biotin is synthesized internally by human cells.

Which vitamin's, specified in the content, requirement in humans is partially fulfilled by intestinal bacteria?

<p>Biotin (Vitamin B7) (C)</p> Signup and view all the answers

In the context of biotin, what specific role does lysine play in biotin-dependent enzymes?

<p>It binds covalently to biotin. (D)</p> Signup and view all the answers

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Study Notes

Biotin (B7)

  • Biotin acts as a coenzyme in carboxylation reactions, serving as a carrier of activated carbon dioxide.
  • Biotin is covalently bound to the ε-amino groups of lysine residues in biotin-dependent enzymes.
  • Biotin deficiency is rare in natural occurrences due to its widespread distribution in food.
  • Intestinal bacteria supply a significant percentage of the biotin requirement in humans.

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