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Biotin: Functions and Properties

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5 Questions

Which biochemical role does biotin fulfill in carboxylation reactions?

It serves as a carrier of activated carbon dioxide.

How is biotin typically bound to biotin-dependent enzymes?

Covalently to the ε-amino groups of lysine residues.

Why does biotin deficiency not occur naturally in humans?

It is widely distributed in food and supplied by intestinal bacteria.

Which vitamin's, specified in the content, requirement in humans is partially fulfilled by intestinal bacteria?

Biotin (Vitamin B7)

In the context of biotin, what specific role does lysine play in biotin-dependent enzymes?

It binds covalently to biotin.

Study Notes

Biotin (B7)

  • Biotin acts as a coenzyme in carboxylation reactions, serving as a carrier of activated carbon dioxide.
  • Biotin is covalently bound to the ε-amino groups of lysine residues in biotin-dependent enzymes.
  • Biotin deficiency is rare in natural occurrences due to its widespread distribution in food.
  • Intestinal bacteria supply a significant percentage of the biotin requirement in humans.

Biotin is a coenzyme involved in carboxylation reactions and has a widespread distribution in food. Learn about its functions and properties in the human body.

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