Biotin and Pyruvate Carboxylation Quiz
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Questions and Answers

Which vitamin is required for pyruvate carboxylase?

  • Vitamin A
  • Vitamin C
  • Vitamin B7 (correct)
  • Vitamin D

What is the product of the carboxylation of pyruvate by pyruvate carboxylase?

  • Malate
  • Oxaloacetate (correct)
  • Acetyl-CoA
  • Phosphoenolpyruvate

Why is OAA reduced to malate?

  • OAA can't cross the mitochondrial membrane (correct)
  • Malate is a more stable molecule
  • Malate is required by PEP carboxykinase
  • OAA is toxic to the cell

Which enzyme oxidatively decarboxylates oxaloacetate to phosphoenolpyruvate?

<p>PEP carboxykinase (B)</p> Signup and view all the answers

What is the role of avidin in biotin absorption?

<p>It binds to biotin and prevents its absorption (C)</p> Signup and view all the answers

Which food source is a good source of avidin?

<p>Egg whites (B)</p> Signup and view all the answers

What is the consequence of biotin deficiency?

<p>All of the above (D)</p> Signup and view all the answers

What is the function of ATP in the carboxylation of pyruvate?

<p>It drives the formation of high-energy enzyme-biotin-CO2 intermediate (D)</p> Signup and view all the answers

What is the fate of malate produced in the mitochondria?

<p>It is transported to the cytosol (A)</p> Signup and view all the answers

What is the final product of the oxidative decarboxylation of OAA?

<p>Phosphoenolpyruvate (C)</p> Signup and view all the answers

Which vitamin is required for pyruvate carboxylase?

<p>Vitamin B7 (C)</p> Signup and view all the answers

What is the product of the carboxylation of pyruvate by pyruvate carboxylase?

<p>Oxaloacetate (C)</p> Signup and view all the answers

Why is OAA reduced to malate?

<p>OAA can't cross the mitochondrial membrane (D)</p> Signup and view all the answers

Which enzyme oxidatively decarboxylates oxaloacetate to phosphoenolpyruvate?

<p>PEP carboxykinase (C)</p> Signup and view all the answers

What is the role of avidin in biotin absorption?

<p>It binds to biotin and prevents its absorption (C)</p> Signup and view all the answers

Which food source is a good source of avidin?

<p>Egg whites (D)</p> Signup and view all the answers

What is the consequence of biotin deficiency?

<p>All of the above (D)</p> Signup and view all the answers

What is the function of ATP in the carboxylation of pyruvate?

<p>It drives the formation of high-energy enzyme-biotin-CO2 intermediate (D)</p> Signup and view all the answers

What is the fate of malate produced in the mitochondria?

<p>It is transported to the cytosol (B)</p> Signup and view all the answers

What is the final product of the oxidative decarboxylation of OAA?

<p>Phosphoenolpyruvate (C)</p> Signup and view all the answers

Which molecule is carboxylated to form oxaloacetate by pyruvate carboxylase?

<p>Pyruvate (B)</p> Signup and view all the answers

What is the fate of oxaloacetate produced by pyruvate carboxylase?

<p>It is reduced to malate (A)</p> Signup and view all the answers

What is the role of PEP carboxykinase in the process of pyruvate carboxylation?

<p>It decarboxylates oxaloacetate to PEP (A)</p> Signup and view all the answers

What is the relationship between avidin and biotin?

<p>They bind to each other (B)</p> Signup and view all the answers

Why is it important to cook egg whites before consuming them?

<p>To denature avidin (A)</p> Signup and view all the answers

What is biotin also known as?

<p>Vitamin H (D)</p> Signup and view all the answers

What drives the formation of the high-energy enzyme-biotin-CO2 intermediate in pyruvate carboxylation?

<p>ATP (A)</p> Signup and view all the answers

What is the end product of the oxidative decarboxylation of oxaloacetate by PEP carboxykinase?

<p>Phosphoenolpyruvate (C)</p> Signup and view all the answers

What happens when there is a lack of biotin in the body?

<p>Pyruvate carboxylation is inhibited (C)</p> Signup and view all the answers

Where does the reduction of malate to oxaloacetate occur in the process of pyruvate carboxylation?

<p>Mitochondria (A)</p> Signup and view all the answers

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