Module 1 - Biotech

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Questions and Answers

The use of non-living organisms to make other products, or to improve animals or to develop microbes, is a simple definition of biotechnology.

False (B)

Which of the following is a product made by biotechnology?

  • Penicillin (correct)
  • Bread
  • Cellphone
  • Cheese

Who among the following develops grafting techniques for plant breeding in 300 BC?

Greeks

Who among the scientists concluded in 1861 that all fermentations are the results of microbial activity?

<p>Louis Pasteur</p> Signup and view all the answers

Technology means something that helps us.

<p>True (A)</p> Signup and view all the answers

A tree is not an organism.

<p>False (B)</p> Signup and view all the answers

Microorganisms can only be seen with a microscope.

<p>True (A)</p> Signup and view all the answers

The prefix 'micro' means very large.

<p>False (B)</p> Signup and view all the answers

Scientists made the greatest advances in biotechnology within the past 75 years.

<p>True (A)</p> Signup and view all the answers

Biotechnology cannot help us in meeting our basic needs such as food, clothing, shelter, health and safety.

<p>False (B)</p> Signup and view all the answers

Biotechnology is a science that uses living things.

<p>True (A)</p> Signup and view all the answers

Biotechnology is a multi-disciplinary field.

<p>False (B)</p> Signup and view all the answers

Biotechnology is any technique that uses living organisms or substances from these organisms to make or modify a product.

<p>True (A)</p> Signup and view all the answers

Genetic Engineering is one of the known scope of Biotechnology.

<p>True (A)</p> Signup and view all the answers

What is Biotechnology?

<p>science that uses living things to change other living things to make products</p> Signup and view all the answers

The word biotechnology can be broken into two parts: bio- is a prefix that means 'life' or 'living things'; technology refers to the use of specific knowledge to change or develop processes and items that benefit people.

<p>True (A)</p> Signup and view all the answers

What do scientist commonly use instead of the word living things when describing biotechnology?

<p>organisms</p> Signup and view all the answers

How can agricultural biotechnology have a positive impact on the environment?

<p>Watering crops with recycled irrigation systems. (B)</p> Signup and view all the answers

What is a genetic engineering advancement directly related to a career in biotechnology?

<p>Creating crop foods that resist insect pests. (C)</p> Signup and view all the answers

In what way is biotechnology useful to law enforcement agencies such as PNP or NBI?

<p>It can help to identify who was present at the scene of a crime. (B)</p> Signup and view all the answers

What are the oldest microbes that have been exploited by humans for their benefit in the ancient times?

<p>Bacteria or yeast</p> Signup and view all the answers

Biotechnology is not new. It has been used for thousands of years for food and production and improvement of health.

<p>True (A)</p> Signup and view all the answers

Who are considered the founders of modern biotechnology?

<p>Stanley Cohen and Herbert Boyer</p> Signup and view all the answers

Which scientist invented the smallpox vaccine?

<p>Edward Jenner (B)</p> Signup and view all the answers

What was the first human protein manufactured in a bacteria?

<p>somatostatin</p> Signup and view all the answers

The U.S. Supreme Court ruled in 1980 that genetically altered life forms can be patented.

<p>True (A)</p> Signup and view all the answers

The first genetically engineered product approved for use by diabetics was human insulin produced using E.coli bacteria.

<p>True (A)</p> Signup and view all the answers

What is a polymerase chain reaction (PCR)?

<p>PCR is a technique that makes unlimited copies of genes.</p> Signup and view all the answers

The Human Genome Project was funded by Congress.

<p>True (A)</p> Signup and view all the answers

What is the name given to the genetically modified rice that provides beta-carotene?

<p>Golden Rice</p> Signup and view all the answers

'Flavr Savr' tomato was genetically engineered to resist rotting.

<p>True (A)</p> Signup and view all the answers

Dolly the sheep was cloned from sheep cells.

<p>True (A)</p> Signup and view all the answers

The U.S. Supreme Court rules that naturally occurring genes cannot be patented.

<p>True (A)</p> Signup and view all the answers

What is the name of the first targeted biological therapy of its kind to receive FDA approval?

<p>Avastin (D)</p> Signup and view all the answers

The human embryonic stem cell lines were established in 2000.

<p>False (B)</p> Signup and view all the answers

The SARS virus was sequenced three weeks after its discovery.

<p>True (A)</p> Signup and view all the answers

What did Japanese scientists create in 2008?

<p>The first DNA molecule made almost entirely of artificial parts. (E)</p> Signup and view all the answers

A trachea derived from stem cells was transplanted into a human recipient in 2011.

<p>True (A)</p> Signup and view all the answers

The FDA issued draft guidelines for biosimilar drugs in 2013.

<p>False (B)</p> Signup and view all the answers

In 2010, researchers at the J. Craig Venter Institute created the first synthetic cell.

<p>True (A)</p> Signup and view all the answers

European scientists begin clinical trials for an anti-HIV biotech medicine produced using genetically modified tobacco.

<p>True (A)</p> Signup and view all the answers

Who is known as the 'father of Philippine Orchidology?

<p>Eduardo Quisumbing (D)</p> Signup and view all the answers

What are two significant contributions made by Ramon C. Barba to the field of biotechnology?

<p>Development of mango flower induction technology and Rapid propagation of tissue culture of sugar cane, rattan and banana.</p> Signup and view all the answers

Who contributed significantly on rice research in the Philippines and is recognised as an authority on growing rice?

<p>Benito S. Vergara</p> Signup and view all the answers

What three scientists are considered to be the early pioneers of modern biotechnology?

<p>Robert Hooke, Antonie van Leeuwenhoek and Theodore Schwann.</p> Signup and view all the answers

What is the 'one gene, one enzyme' hypothesis and who proposed this theory?

<p>The 'one gene, one enzyme' hypothesis, proposed by George Beadle and Edward Tatum, suggests that each gene controls the production of a specific enzyme.</p> Signup and view all the answers

Linus Pauling described sickle cell anemia calling it a molecular disease.

<p>True (A)</p> Signup and view all the answers

Max Delbruck organized a course to study a type of bacterial virus consisting of a protein-coat containing DNA.

<p>True (A)</p> Signup and view all the answers

Erwin Chargaff determined there is always a ratio of 1:1 adenine to thymine in DNA.

<p>True (A)</p> Signup and view all the answers

Alfred Hershey and Margaret Chase used radioactive labelling to determine that it is the DNA, not protein which carries instructions in assembling new phages.

<p>True (A)</p> Signup and view all the answers

James Watson and Francis Crick determined the double helix structure of DNA.

<p>True (A)</p> Signup and view all the answers

Frederick Sanger sequenced insulin (protein) from pork and bovine insulin.

<p>True (A)</p> Signup and view all the answers

Arthur Kornberg discovered DNA polymerase.

<p>True (A)</p> Signup and view all the answers

Marshall Niroenberg and Severo Ochoa determined that a sequence of three nucleotide bases determine each of 20 amino acids.

<p>True (A)</p> Signup and view all the answers

Paul Berg, Stanley Cohen, and Herbert Boyer developed ways to cut and splice DNA using recombinant DNA techniques with restriction enzymes.

<p>True (A)</p> Signup and view all the answers

Stanley Cohen and Herbert Boyer produced the first recombinant DNA organism, beginning of genetic engineering considered to be the birth of modern biotechnology.

<p>True (A)</p> Signup and view all the answers

George Kohler and Cesar Milstein showed that fusing cells can generate monoclonal antibodies.

<p>True (A)</p> Signup and view all the answers

Flashcards

What is biotechnology?

The practical use of knowledge in biology to create products or processes that benefit humans.

What are microorganisms?

Microorganisms are microscopic living things, like bacteria and yeast.

What does "multidisciplinary" mean?

Branches of science working together, like biology, chemistry and engineering.

What is fermentation?

The process of breaking down sugar into alcohol and carbon dioxide, often used to produce alcoholic drinks or bread.

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What is microbiology?

The branch of biology that studies microorganisms, like bacteria, viruses, and fungi.

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What is an organism?

Any living thing, like a plant, animal, or even a bacteria.

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What were the earliest uses of biotechnology?

They used yeast for leavening bread and fermenting beer.

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How did the Chinese use biotechnology in ancient times?

The use of moldy soybean curds to treat boils.

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What is a microscope?

A magnifying device that allows the observation of microscopic objects.

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What important biological discovery happened in 1663?

The discovery of cells by Robert Hooke.

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What important biological discovery happened in 1675?

The first observations of protozoa and bacteria, by Antoni van Leeuwenhoek.

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What important biological discovery happened in 1786?

The invention of the smallpox vaccine by Edward Jenner, paving the way for modern immunizations.

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What important biological discovery happened in 1859?

The publication of "Origin of Species" by Charles Darwin, explaining the theory of evolution.

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What important biological discovery happened in 1861?

Louis Pasteur proposed the "Germ Theory of Disease", linking microorganisms to illnesses.

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What important biological discovery happened in 1865?

Gregor Mendel's studies on how traits are passed from generation to generation, laying the foundation for genetics.

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What important biological discovery happened in 1869?

Johann Meischer isolated DNA from the nuclei of white blood cells, the first step in understanding DNA's role in inheritance.

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What important biological discovery happened in 1902?

The discovery that genes are carried on chromosomes by Thomas Hunt Morgan, linking genes to the physical structures in the cell.

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What important biological discovery happened in 1910?

Walter Sutton coined the term "gene" and proposed chromosomes carry the genetic material.

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What important biological discovery happened in 1944?

Oswald Avery, Colin MacLeod, and Maclyn McCarty proved that DNA carries genetic information, not protein.

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What is the genetic code?

A sequence of three nucleotide bases (a codon) determines each amino acid in a protein.

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What important biological discovery happened in 1953?

The discovery of the double helix structure of DNA by James Watson and Francis Crick, revolutionizing biology.

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What important biological discovery happened in 1973?

The development of gene cloning and recombinant DNA techniques by Stanley Cohen and Herbert Boyer, marking the beginning of genetic engineering.

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What significant biotechnological achievement happened in 1977?

Genentech produced the first human protein manufactured in bacteria, somatostatin, marking a key milestone in modern biotechnology.

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What important biological discovery happened in 1984?

Kary Mullis developed the polymerase chain reaction (PCR), a technique for amplifying DNA fragments, revolutionizing molecular biology.

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What legal decision in 1980 had a major impact on biotechnology?

The US Supreme Court ruled that genetically altered life forms can be patented, opening up new possibilities for commercializing biotech inventions.

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What important biological achievement happened in 1997?

Dolly, the first mammal cloned from an adult cell, was born, demonstrating the power of cloning technology.

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What important biotechnological development happened in 2001?

The development of "Golden Rice", genetically modified to produce beta-carotene, aimed at combating vitamin A deficiency.

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What is the contribution of Ramon C. Barba to biotechnology?

Ramon C. Barba developed mango flower induction technology for year-round mango production.

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What is the contribution of Emerita V. De Guzman to biotechnology?

Emerita V. De Guzman spearheaded the research on rapid propagation of Makapuno coconut.

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What is the contribution of Pedro B. Escuro to biotechnology?

Pedro B. Escuro developed dwarf, high-yielding C4 rice varieties for commercial production.

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What is the contribution of Eduardo A. Quisumbing to biotechnology?

Eduardo A. Quisumbing is known as the "father of Philippine Orchidology" and conducted extensive research on Philippine plants.

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What is the contribution of Benito S. Vergara to biotechnology?

Benito S. Vergara contributed significantly to rice research, developing varieties resistant to flooding, cold, and other challenges.

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What is the contribution of William G. Padolina to biotechnology?

William G. Padolina is a multi-awarded scientist in the field of biotechnology and chemistry of natural products.

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What is the contribution of Dioscoro Umali to biotechnology?

Dioscoro Umali is known for breeding improved varieties of food crops and advocating for sustainable agriculture practices.

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What is the contribution of Evelyn Mae T. Mendoza to biotechnology?

Evelyn Mae T. Mendoza researched plant biochemistry, focusing on the nutritional value of indigenous plants.

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What is the contribution of Baldomero Olveria, Jr. to biotechnology?

Baldomero Olveria, Jr. conducted research in molecular biology and biochemistry, isolating key DNA enzymes.

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What is the contribution of Asuncion Raymundo to biotechnology?

Asuncion Raymundo is a researcher in the chemistry of natural products, applying biotechnology and microbial genetics to agriculture.

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What is environmental biotechnology?

The use of biological agents or processes to address environmental problems, such as bioremediation.

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Study Notes

Biotechnology Module 1

  • This module introduces the concept of biotechnology.
  • It explores the scope, definition, and history of biotechnology.
  • It discusses the various applications and uses of biotechnology, including its benefits and potential risks.
  • It highlights the importance of biotechnology in human life, agriculture, industry, and medicine, including poverty alleviation, and raising the standard of living globally, particularly in developing countries like the Philippines.
  • It covers important scientists and their notable discoveries within the field of biotechnology.
  • The module provides a timeline of critical events and advancements in biotechnology.
  • The module includes activities to help enhance learning comprehension and critical thinking.
  • It underscores the role of biotechnology in addressing current problems and improving the quality of life through various applications and useful products.
  • It covers the practical applications in health, food production, and environmental conservation.
  • The materials in the module are sourced from diverse perspectives and cater to different learning styles.

Biotechnology: History of Biotechnology

  • Biotechnology is a process where raw materials are biologically improved into useful products.
  • This has advanced human life, and will continue in the future.

What is Biotechnology

  • Biotechnology combines "bio" (life) and "technology" (practical application of knowledge) to emphasize practical use of living things for production.
  • Biotechnology uses living organisms or parts of them to create products for human benefit or changing them to be more useful.

What I Need to Know

  • Define biotechnology
  • Trace the historical development of biotechnology
  • Describe and explain the contributions of Filipino and foreign biotechnologists to modern biotechnology.
  • Recognize the major scientists, their discoveries and modern contributions to biotechnology
  • Link discoveries with broader developments, how discoveries impact our lives.

What I Know

  • Simple definition of biotechnology
  • Which are most closely related to biotechnology?
  • Which are products of biotechnology
  • Who developed grafting techniques in plant breeding?
  • Who concluded that all fermentation processes are caused by microbes?

What's In

  • Review on prior knowledge on biotechnology
  • Example activity to connect previous knowledge with new concepts
  • Activity to review past lessons on biotechnology

What's New

  • Introduction of new concepts of biotechnology
  • Activity to determine knowledge gaps
  • Explanation of new biotechnology related topics

What is It

  • Deep dive into the concept of biotechnology with definitions, examples, and explanations
  • A brief discussion of concepts, skills, and discovery elements of biotechnology

What's More

  • Independent practice activities to solidify understanding
  • Exercises to practice skills
  • Answers may be found towards the end of the book

What I Have Learned

  • Summary of the lesson
  • Questions or blank sentences/paragraphs for the learners to fill in to express their understanding.

What I Can Do

  • Application of knowledge and skills in real-world situations
  • Activities to apply learned knowledge

Assessment

  • Multiple-choice questions to evaluate student understanding
  • Evaluation activities to assess comprehension and mastery of the knowledge

Additional Activities

  • Enrich learning and skill retention activities related to the lesson

Answer Key

  • Solutions for all activities, and exercises, in the module.

References

  • List of all external sources for the biotechnology module research.

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