Biostatistics Study Design
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Questions and Answers

Biostatisticians are not in high demand in the job market.

False

The field of biostatistics is not growing rapidly.

False

Cohort studies are used to determine prevalence.

False

Modern biomedical technologies have created fewer challenges for biostatisticians.

<p>False</p> Signup and view all the answers

Sample size is a consideration in study design.

<p>True</p> Signup and view all the answers

Biostatisticians do not work at the interface of statistics with biomedicine.

<p>False</p> Signup and view all the answers

Cohort studies measure events in reverse chronological order.

<p>False</p> Signup and view all the answers

Statistics is not referred to as the grammar of science.

<p>False</p> Signup and view all the answers

Cohort studies are used to determine the prevalence of a condition.

<p>False</p> Signup and view all the answers

The incidence rate of HIV infection in the given population is 2.8% per year.

<p>False</p> Signup and view all the answers

Cross-sectional studies are used to determine the incidence of a condition.

<p>False</p> Signup and view all the answers

The incidence proportion is calculated by dividing the number of cases by the number of years.

<p>False</p> Signup and view all the answers

Cohort studies can be prospective or retrospective.

<p>True</p> Signup and view all the answers

Knowing the prevalence of a condition is not important for a clinician.

<p>False</p> Signup and view all the answers

The prevalence of a disease is the number of new cases reported in a population over a certain period of time.

<p>False</p> Signup and view all the answers

The formula for calculating prevalence is (number of affected people / total population) * 100.

<p>True</p> Signup and view all the answers

In the given example, the prevalence of the disease is 10%.

<p>False</p> Signup and view all the answers

Point prevalence measures the number of cases of a health event over a 12-month period.

<p>False</p> Signup and view all the answers

Incidence is a measure of the number of existing cases of a disease in a population.

<p>False</p> Signup and view all the answers

There are only two ways to calculate prevalence in epidemiology.

<p>False</p> Signup and view all the answers

Incidence is a measure of the number of cases of a health event in reference to the total lifetime.

<p>False</p> Signup and view all the answers

A stable number of new cases of a disease will lead to a decrease in prevalence over time.

<p>False</p> Signup and view all the answers

Study Notes

Biostatistics and Study Design

  • Biostatisticians work at the interface of statistics with biomedicine to solve important design and analysis questions.
  • The field of biostatistics is growing rapidly, creating new challenges and opportunities, and biostatisticians are in high demand.

Importance of Statistics

  • Statistics is the grammar of science (Karl Pearson).
  • Statistics is essential for solving real-life scientific problems.

Study Design Objective

  • The objective of a study is to determine the rational of the study, sample, and expected outcomes.
  • Study design involves type of study, sample size, and power analysis.

Types of Study Design

  • Cohort studies are used to study incidence, causes, and prognosis.
  • Cross-sectional studies are used to determine prevalence.

Incidence and Prevalence

  • Prevalence looks at existing cases, while incidence looks at new cases.
  • Prevalence can be calculated as a percentage using the formula: (number of cases / population size) x 100.
  • Incidence can be calculated as a proportion or rate, such as cases per 1,000 person-years.

Prevalence Measures

  • Point prevalence: The number of cases of a health event at a certain time.
  • Period prevalence: The number of cases of a health event in a specific time period.
  • Lifetime prevalence: The number of cases of a health event in reference to the total lifetime.

Cohort Studies

  • Cohort studies are the best method for determining incidence and natural history of a condition.
  • Cohort studies can be prospective or retrospective and may involve comparing two cohorts.

Cross-Sectional Studies

  • Cross-sectional studies are primarily used to determine prevalence.
  • Prevalence is important for clinicians because it influences the likelihood of a diagnosis and the predictive value of an investigation.

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Description

Learn about the role of biostatisticians in solving design and analysis questions in biomedical research, and the challenges posed by modern technologies generating large amounts of data.

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