15 Questions
What is the definition of biopharmaceutics?
The study of the chemical and physical properties of drugs and the biological effects they produce.
What does pharmacokinetics study?
The absorption, distribution, biotransformation and elimination of drugs.
What does the biopharmaceutical classification system study?
The impact of physicochemical properties of drugs on drug delivery to the body under normal or pathologic conditions.
What does the study of biowaver focus on?
Criteria for waiving in vivo bioequivalence studies for certain drugs.
What is the definition of the Biopharmaceutical Classification System (BCS)?
A framework for classifying drugs based on their solubility and permeability
What does solubility refer to in the context of drug substances?
The process in which a solid substance solubilizes in a given solvent
What is permeability related to in the context of drug substances?
The process of drug absorption in the human body
What is dissolution in the context of drug substances?
The process in which solid substance solubilizes in a given solvent
Which class in the Biopharmaceutical Classification System (BCS) is considered ideal for oral route administration?
Class I
What are the two key factors used to classify drug compounds in the Biopharmaceutical Classification System (BCS)?
Solubility and dissolution rate
What does the Biopharmaceutical Classification System (BCS) aim to provide a scientific approach for?
Predicting in vivo pharmacokinetics of oral immediate release drug products
Which factor determines if a drug substance is considered highly permeable?
The extent of absorption in human determined to be 90% or more
What is the main purpose of the Biopharmaceutical Classification System (BCS)?
To provide a scientific framework for predicting in vivo pharmacokinetics
What determines if a drug substance is classified as Class II in the Biopharmaceutical Classification System (BCS)?
Rapid dissolution but slow absorption
What media is used for testing dissolution as per the Biopharmaceutical Classification System (BCS)?
1.0 N HCl or simulated gastric fluid without enzyme, pH 1.2
Test your knowledge about biopharmaceutics, including factors affecting the classification system, biopharmaceutical classes, application, boundaries, biowaiver criteria, and more.
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