Bioorthogonal Reactions and Molecule Labeling
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Questions and Answers

Which type of reactions are often unavailable in living systems?

  • Water- and redox- sensitive reactions
  • Reactions prone to nucleophilic attack
  • Reactions with large kinetic barriers
  • All of the above (correct)

    • What is the main goal of functionalization in a labeling experiment?

  • To increase the kinetic barriers
  • To perturb the system
  • To react chemospecifically with an optical probe (correct)
  • To introduce distracting reactive materials

    • What is required for a labeling experiment to be considered robust?

  • Non-specific functionalization that perturbs the system
  • Non-specific functionalization that does not perturb the system
  • Specific functionalization that perturbs the system
  • Specific functionalization that does not perturb the system (correct)

    • Why are many reactions normally available to organic chemists in the laboratory unavailable in living systems?

    <p>They are water- and redox- sensitive</p> Signup and view all the answers

    What is the purpose of bioorthogonal chemistry?

    <p>To develop reactions that proceed chemospecifically in living systems</p> Signup and view all the answers

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