Heredity (hard MCQ)

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Questions and Answers

During DNA replication, which of the following mechanisms is most crucial for ensuring that each new DNA molecule consists of one original and one newly synthesized strand?

  • The dispersive model, where each strand of the new DNA molecules contains a mixture of old and newly synthesized segments.
  • The progressive model, where the original strand is used as a template, and the new DNA molecule is synthesized in fragments and later joined together.
  • The semi-conservative model, where each new DNA molecule consists of one original strand and one newly synthesized strand. (correct)
  • The conservative model, where the original DNA molecule remains intact and a completely new double-stranded helix is synthesized.

Consider a cell undergoing meiosis. If non-disjunction occurs during meiosis I, what is the likely outcome regarding the chromosome number in the resulting daughter cells?

  • All four daughter cells will have a normal chromosome number.
  • One daughter cell will have an extra chromosome (n+1), one will have a missing chromosome (n-1), and two will be normal (n).
  • Two daughter cells will be diploid, and two will be haploid.
  • Two daughter cells will have an extra chromosome (n+1), and two will have a missing chromosome (n-1). (correct)

In a monohybrid cross, if the F1 generation displays an intermediate phenotype that is a blend of both parental traits, which genetic principle is most likely at play?

  • Recessive epistasis, where the presence of a recessive allele at one locus hides the effect of alleles at another locus.
  • Complete dominance, where one allele masks the expression of the other.
  • Incomplete dominance, where the heterozygous phenotype is a blend of the homozygous phenotypes. (correct)
  • Co-dominance, where both alleles are equally expressed in the phenotype.

During DNA replication, what is the primary role of single-strand binding (SSB) proteins?

<p>To prevent the separated DNA strands from re-annealing during replication. (A)</p> Signup and view all the answers

If a cell line exhibits uncontrolled division due to a mutation causing a non-functional G1 checkpoint, which protein is most likely affected by this mutation?

<p>p53, a tumor suppressor protein that regulates cell cycle arrest and apoptosis. (C)</p> Signup and view all the answers

In a dihybrid cross involving two unlinked genes, what phenotypic ratio is expected in the F2 generation if both genes exhibit complete dominance?

<p>9:3:3:1 (C)</p> Signup and view all the answers

Consider a scenario where a mutation in a DNA repair enzyme leads to an accumulation of thymine dimers. Which specific type of DNA repair mechanism is most likely compromised?

<p>Nucleotide excision repair (NER) (B)</p> Signup and view all the answers

If a geneticist discovers that two genes on the same chromosome assort independently, what is the most likely explanation for this observation?

<p>The genes are located far apart on the chromosome, allowing for frequent crossing over. (D)</p> Signup and view all the answers

In biotechnology, what is the primary purpose of using CRISPR-Cas9 technology?

<p>To precisely edit genes within living organisms. (D)</p> Signup and view all the answers

How does telomerase overcome the end replication problem in eukaryotic chromosomes?

<p>By adding repetitive DNA sequences to the 3' end of chromosomes, thus extending the template strand. (D)</p> Signup and view all the answers

If a cell population shows a significantly increased rate of homologous recombination, what is the most likely consequence?

<p>Increased genomic instability and potential for chromosomal rearrangements. (D)</p> Signup and view all the answers

What is the significance of alternative splicing in eukaryotic gene expression?

<p>It allows a single gene to code for multiple proteins. (D)</p> Signup and view all the answers

In a pedigree analysis, if a trait appears to skip generations and affects males and females equally, what is the most likely mode of inheritance?

<p>Autosomal recessive (D)</p> Signup and view all the answers

What is the primary function of DNA methylation in gene regulation?

<p>To decrease gene expression by altering chromatin structure. (A)</p> Signup and view all the answers

During meiosis, what is the role of the synaptonemal complex?

<p>To facilitate the alignment of homologous chromosomes and crossing over. (C)</p> Signup and view all the answers

Consider a scenario where a new drug inhibits the function of DNA ligase. What direct effect would this have on DNA replication?

<p>It would prevent the joining of Okazaki fragments on the lagging strand. (C)</p> Signup and view all the answers

If a scientist discovers that a particular mRNA molecule has a longer than expected poly(A) tail, what might be the likely consequence?

<p>Enhanced mRNA stability and increased protein production. (C)</p> Signup and view all the answers

What role do topoisomerases play during DNA replication?

<p>To relieve torsional stress caused by DNA unwinding. (A)</p> Signup and view all the answers

How does RNA interference (RNAi) regulate gene expression?

<p>By cleaving mRNA molecules or blocking their translation. (C)</p> Signup and view all the answers

In the context of gene linkage, what does a high recombination frequency between two genes indicate?

<p>The genes are located far apart on the same chromosome. (D)</p> Signup and view all the answers

Flashcards

DNA Replication

The process of producing identical copies of DNA.

Cell Division

The process by which a cell divides into two identical daughter cells.

Inheritance

The process by which traits are passed from parents to offspring.

Biotechnology

The process by which scientists manipulate DNA to create new products or genetically modified organisms.

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Gene Linkage

Genes located on the same chromosome that tend to be inherited together.

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Study Notes

  • BioNinja provides resources for studying heredity.
  • Course resources include syllabus outlines, command terms, reporting skills, and practical work guidance.
  • Topics covered are biomolecules, cells, metabolism, genetics, heredity, equilibrium, body systems, plant systems, biodiversity, nutrition, ecology, and human impacts.
  • Themes explored are unity and diversity, form and function, interdependencies, and continuity/change.
  • Review resources include powerpoints, topic notes, summaries, and worksheets.
  • Topics covered in the heredity unit include DNA replication, cell division, inheritance, gene linkage, and biotechnology.

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