Biomolecules and Enzymes: False Statements
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Questions and Answers

Which statement correctly describes the behavior of acids and bases in aqueous solutions?

  • Acids donate hydrogen ions, while bases accept hydrogen ions. (correct)
  • Acids accept hydrogen ions, while bases donate hydrogen ions.
  • Acids donate hydroxide ions, while bases accept hydrogen ions.
  • Acids and bases both donate hydrogen ions.

What is the implication of a $\Delta G$ (Gibbs free energy change) of zero in a biochemical reaction?

  • The reaction requires a large input of energy to proceed.
  • The rate of the forward reaction is maximized.
  • The reaction proceeds spontaneously to completion.
  • The system is at equilibrium, with no net change occurring. (correct)

A patient's blood tests reveal a serum pH of 7.7. Which condition is the patient most likely experiencing?

  • Alkalosis (correct)
  • Neutrality
  • Normal blood pH
  • Acidosis

If a biochemist is studying a protein and discovers it has been improperly folded, which of the following would be most helpful in rescuing the protein?

<p>Chaperone (C)</p> Signup and view all the answers

In the context of hemoglobin function in the lungs, which condition facilitates efficient oxygen binding?

<p>High oxygen concentration (B)</p> Signup and view all the answers

What structural characteristic is commonly associated with globular proteins?

<p>Multiple folding of polypeptide chains into an ellipsoidal shape (D)</p> Signup and view all the answers

What is the role of enzymes in biochemical reactions?

<p>To lower the activation energy by stabilizing the transition state. (D)</p> Signup and view all the answers

What oxidation state is characteristic of the iron atom within the heme group of hemoglobin when it is able to bind oxygen?

<p>Ferrous ($Fe^{2+}$) (A)</p> Signup and view all the answers

A researcher is investigating the effect of increasing substrate concentration on the rate of an enzymatic reaction. What is the expected outcome if all other conditions remain constant?

<p>The reaction rate will increase to a maximum velocity and then plateau. (D)</p> Signup and view all the answers

Which of the following distinguishes vitamins B9, Cobalamin, Niacin, and C from other vitamins?

<p>They are water-soluble. (A)</p> Signup and view all the answers

Flashcards

Acids vs Bases

Acids donate hydrogen ions, while bases accept them.

Hemoglobin in Lungs

High oxygen levels saturate hemoglobin.

Sulfur-containing Amino Acids

Some amino acids contain sulfur.

Enzyme Role

Enzymes are not consumed or permanently altered.

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Pellagra Cause

Niacin (Vitamin B3) deficiency causes Pellagra.

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Thiamine Deficiency Cause

Thiamine deficiency is caused by chronic alcoholism.

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ΔG = 0

No change occurs, system is balanced.

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Exergonic vs exothermic

Exergonic reactions usually release heat (exothermic).

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Amino Acids and Proteins

Proteins are made of amino acids.

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High Serum pH (7.7)

Patient is experiencing alkalosis.

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Chaperone Function

Proteins misfold and need to be refolded correctly.

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Globular Proteins

Multiple polypeptide folding that is ellipsoidal.

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The iron heme

The Iron moves toward the plane.

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Fetus vs adult hemoglobin

Hemoglobin changes during development.

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Iron Atom Charge

Iron atom has a charge of 2+.

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Lower activation energy?

Enzymes lower the activation energy by stabilizing the transition state.

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Water-soluble vitamins

Vitamins B9, cobalamin, Niacin, and C are water-soluble.

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Study Notes

  • Answer = 0 questions

False Statements on Biomolecules and Enzymes

  • Lipids are not composed of fatty acids and amino acids as monomers.

  • Tetrameric proteins do not consist of two polypeptide chains.

  • The difference between amino acids is not limited to the carboxyl group.

  • Peptide bonds do not stabilize the secondary structure of a protein.

  • Not all proteins can be renatured after denaturation.

  • Beta sheets are not examples of a protein's tertiary structure.

  • The T form of hemoglobin does not have a high affinity for oxygen.

  • Collagen is not the dominant globular protein in humans.

  • Ehlers-Danlos syndrome is not caused by a mutation in the elastin gene.

  • Nucleases do not catalyze the hydrolysis of proteins into their component amino acids.

  • Reaction velocity does not always increase with increasing substrate concentration.

  • Competitive inhibitors do not decrease the Km for the substrate.

  • Non-competitive inhibitors do not bind to the active site of an enzyme.

  • Biotin aids different reactions to hydroxylation of lysine and proline residues in collagen synthesis.

  • Competitive inhibitors do not resemble the structure of an enzyme.

  • Rhodopsin does not contain Vitamin E protein opsin.

  • The parathyroid and adrenal glands do not play a significant role in plasma calcium maintenance.

  • Answer = 1 questions

True Statements on Biomolecules and Enzymes

  • Acids donate hydrogen ions in water, while bases accept them.
  • In the lungs, high oxygen concentrations saturate hemoglobin.
  • Some amino acids contain sulfur atoms.
  • Enzymes remain unchanged after participating in a reaction.
  • Pellagra can be caused by niacin deficiency.
  • Chronic alcoholism can cause severe thiamine deficiency.
  • At equilibrium, ΔG is zero, indicating no net change in the system.
  • Exergonic reactions are also exothermic.
  • Amino acids are the monomers of proteins.
  • A patient with a serum pH of 7.7 has alkalosis.
  • Both L and D amino acids are present in humans
  • Chaperones help improperly folded proteins refold correctly.
  • Globular proteins are ellipsoidal due to multiple polypeptide chain folding.
  • Iron moves towards the heme plane when O2 binds.
  • Fetuses and adults have different types of hemoglobin chains.
  • Hemoglobin heme typically contains iron in the ferrous state (Fe2+).
  • Enzymes lower activation energy by stabilizing the transition state.
  • Vitamins B9, cobalamin, niacin, and C are water-soluble.

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Description

Identify false statements about biomolecules and enzymes. Topics covered include lipids, proteins, hemoglobin, collagen, enzyme inhibition, and reaction kinetics. Test your understanding of molecular biology.

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