Biomembrane Structure and Function
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Questions and Answers

What forms the hydrophobic core in a phospholipid bilayer?

  • Integral proteins
  • Cholesterol molecules
  • Long fatty acyl side chains (correct)
  • Polar head groups
  • Cholesterol increases the rigidity of phospholipid bilayers.

    False (B)

    What role do proteins in the plasma membrane play in cellular function?

    They selectively absorb nutrients, expel wastes, and maintain intracellular ionic composition.

    The presence of glycolipids contributes to membrane __________.

    <p>asymmetry</p> Signup and view all the answers

    Match the following components with their functions:

    <p>Integral proteins = Selective nutrient absorption Cholesterol = Determines bilayer fluidity Glycolipids = Membrane asymmetry Peripheral proteins = Cell interaction and communication</p> Signup and view all the answers

    What is the effect of heating on a phospholipid bilayer?

    <p>It undergoes a phase transition to a more fluid state. (D)</p> Signup and view all the answers

    All cellular membranes possess a cytosolic face and an extracellular matrix.

    <p>False (B)</p> Signup and view all the answers

    What primarily gives plant cells their shape and rigidity?

    <p>The cell wall, built mainly of cellulose.</p> Signup and view all the answers

    Flashcards

    Phospholipid bilayer

    A membrane structure with hydrophobic cores and polar head groups on surfaces.

    Membrane asymmetry

    The uneven distribution of proteins and lipids in the bilayer faces.

    Fluid mosaic model

    Describes the cell membrane as a fluid and flexible layer of lipids and proteins.

    Cholesterol's role

    Cholesterol maintains membrane fluidity, influencing how rigid or flexible the membrane is.

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    Integral proteins

    Proteins that penetrate the lipid bilayer, involved in transport and communication.

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    Cytosolic vs Exoplasmic face

    The inner and outer sides of the membrane with distinct protein orientations.

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    Cell wall in plants

    A rigid structure made of cellulose that gives shape and support to plant cells.

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    Extracellular matrix

    The network of proteins and carbohydrates outside animal cells providing support and communication.

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    Study Notes

    Phospholipid Bilayer Structure

    • Phospholipid bilayers have acyl chains oriented inward, creating a hydrophobic core and polar heads facing outward.
    • This structure forms the basis of all biomembranes.

    Biomembrane Composition and Function

    • Biomembranes contain phospholipids, proteins (integral and peripheral), glycoproteins, cholesterol, and glycolipids.
    • Different membranes have unique protein compositions, enabling diverse functions.
    • Membranes enclose compartments with distinct cytosolic and exoplasmic faces.
    • Membrane asymmetry arises from the specific orientation of integral and peripheral proteins, and the exclusive presence of glycolipids on the exoplasmic face.

    Membrane Fluidity and Dynamics

    • Membrane components (proteins and lipids) are largely mobile within the bilayer.
    • The fluid mosaic model depicts membranes as a dynamic mosaic of lipids and proteins.
    • Bilayer fluidity is temperature-dependent, transitioning from gel-like to fluid states over a specific temperature range.
    • Cholesterol significantly affects fluidity, with its impact varying by membrane composition.
    • Cells regulate phospholipid composition to maintain optimal fluidity.

    Membrane Protein Functions

    • Plasma membrane proteins are vital for nutrient uptake, waste expulsion, and ion homeostasis.
    • Plasma membrane proteins link membranes to the cytoskeleton and extracellular matrix/cell wall.
    • Cell-to-cell communication in multicellular organisms occurs via specialized plasma membrane proteins.

    Plant Cell Walls

    • Plant cell walls, primarily composed of cellulose, define cell shape and provide rigidity.
    • Animal cells lack cell walls but have an extracellular matrix composed of collagen and glycoproteins.

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    Description

    Explore the intricate structure and functions of biomembranes, focusing on the phospholipid bilayer and its components. Understand how the fluid mosaic model explains the dynamics of membrane behavior and the implications of membrane asymmetry on cellular functionality.

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