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Questions and Answers
What is cell division?
What is cell division?
The reproduction of cells.
What is the cell cycle?
What is the cell cycle?
The life of a cell from the time it is first formed from a dividing parent cell until its own division into two daughter cells.
What is a genome?
What is a genome?
The genetic material of an organism or virus.
What is a chromosome?
What is a chromosome?
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What is chromatin?
What is chromatin?
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What is a chromatid?
What is a chromatid?
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What is a centromere?
What is a centromere?
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What are somatic cells?
What are somatic cells?
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What are gametes?
What are gametes?
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What are sister chromatids?
What are sister chromatids?
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What is mitosis?
What is mitosis?
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What is cytokinesis?
What is cytokinesis?
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What is the mitotic (M) phase?
What is the mitotic (M) phase?
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What is interphase?
What is interphase?
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What happens during prophase?
What happens during prophase?
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What is prometaphase?
What is prometaphase?
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What occurs during metaphase?
What occurs during metaphase?
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What happens in anaphase?
What happens in anaphase?
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What happens during telophase?
What happens during telophase?
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What is a mitotic spindle?
What is a mitotic spindle?
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What is a centrosome?
What is a centrosome?
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What is an aster?
What is an aster?
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What is a kinetochore?
What is a kinetochore?
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What is binary fission?
What is binary fission?
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What is the origin of replication?
What is the origin of replication?
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What is the cell cycle control system?
What is the cell cycle control system?
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What is a checkpoint?
What is a checkpoint?
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What is a growth factor?
What is a growth factor?
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What is density-dependent inhibition?
What is density-dependent inhibition?
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What is anchorage dependence?
What is anchorage dependence?
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What are the functions of cell division?
What are the functions of cell division?
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When is DNA replicated and why is this crucial?
When is DNA replicated and why is this crucial?
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What is the difference between replicated and unreplicated chromosomes?
What is the difference between replicated and unreplicated chromosomes?
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Does mitosis change ploidy? How do daughter cells compare to the parent cell?
Does mitosis change ploidy? How do daughter cells compare to the parent cell?
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How does binary fission compare to cell division in eukaryotes?
How does binary fission compare to cell division in eukaryotes?
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What is the G0 phase?
What is the G0 phase?
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How is control of the cell cycle related to cancer?
How is control of the cell cycle related to cancer?
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Study Notes
Cell Division and Cycle
- Cell division is the process through which cells reproduce.
- The cell cycle encompasses the life span of a cell from formation until its division into daughter cells.
- The genome represents the entirety of genetic material in an organism or virus.
Chromosomes and Chromatin
- Chromosomes consist of a single DNA molecule and associated proteins; eukaryotes have multiple linear chromosomes in the nucleus, while prokaryotes typically possess a single circular chromosome.
- Chromatin refers to the DNA and protein complex in eukaryotes, existing as long thin fibers when the cell is not dividing.
Chromatids and Centromeres
- A chromatid is one copy of a duplicated chromosome, attached to its identical copy by a centromere.
- The centromere is the attachment point for sister chromatids, essential for proper chromosome movement during cell division.
Types of Cells
- Somatic cells are all body cells excluding reproductive cells (gametes), which are the sperm and egg.
Mitosis and Cytokinesis
- Mitosis refers to the division of the genetic material in the nucleus, while cytokinesis involves the division of the cytoplasm following mitosis.
- The mitotic phase includes both mitosis and cytokinesis, typically the shortest phase of the cell cycle.
Interphase and Phases of Mitosis
- Interphase accounts for 90% of the cell cycle and includes G1 (first phase), S (chromosome duplication), and G2 (final preparations for mitosis).
- Prophase, prometaphase, metaphase, anaphase, telophase outline the stages of mitosis:
- Prophase: Chromatin condenses into visible chromosomes; mitotic spindle begins to form.
- Prometaphase: Nuclear envelope fragments; kinetochores develop on chromatids.
- Metaphase: Chromosomes align at the metaphase plate with sister chromatids connected to microtubules from opposite poles.
- Anaphase: Cohesin proteins are cleaved; sister chromatids move to opposite sides.
- Telophase: Formation of daughter nuclei with reappearance of nucleoli and decondensation of chromosomes.
Cell Division Mechanisms
- Cytokinesis differs between animal (cleavage furrow formation) and plant cells (cell plate formation).
- The mitotic spindle, made of microtubules, organizes during cell division, initiated by the centrosome.
Regulatory Mechanisms
- The cell cycle control system regulates cell cycle events through a series of checkpoints that monitor progress and signal when to divide or halt.
- Major checkpoints are located in G1, G2, and M phases, ensuring proper division.
- Growth factors are proteins that stimulate cell division, while density-dependent inhibition and anchorage dependence ensure cells stop dividing under certain conditions.
DNA Replication and Ploidy
- DNA replication occurs during the S phase, crucial for ensuring each daughter cell inherits a complete set of chromosomes.
- Replicated chromosomes consist of two identical DNA double helices; unreplicated chromosomes have a single double helix.
- Mitosis does not alter ploidy; daughter cells remain diploid like the parent cell.
Binary Fission and Cell Cycle
- Binary fission is a type of asexual reproduction found in prokaryotes and some eukaryotes, akin to mitosis in process.
- G0 phase represents a non-dividing state for cells that have exited the cycle.
- Cancer cells often bypass regulatory signals, leading to uncontrolled division.
Summary and Key Points
- Cell division is essential for growth and repair in multicellular organisms.
- The concerted actions of various phases, checkpoints, and regulatory mechanisms ensure a successful cell cycle, critical for maintaining healthy organismal function.
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Description
Discover essential terms and definitions related to the cell cycle with this set of flashcards. Learn about key concepts such as cell division, chromosomes, and genomes to enhance your understanding of cellular biology.