Biology: Polypeptides and Proteins
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Questions and Answers

What is the structure of haemoglobin according to the text?

  • Haemoglobin consists of two polypeptides of two different kinds
  • Haemoglobin consists of four polypeptides of the same kind
  • Haemoglobin consists of two polypeptides of the same kind
  • Haemoglobin consists of four polypeptides of two different kinds (correct)

What is the preferred method of amino acid composition analysis for proteins according to the text?

  • Alkaline hydrolysis
  • Acid hydrolysis at 110°C for 72 hours
  • Acid hydrolysis at 110°C for 24 hours (correct)
  • Acid hydrolysis at 110°C for 48 hours

Which amino acid is destroyed by acid hydrolysis and must be estimated by other means?

  • Threonine
  • Serine
  • Tryptophan (correct)
  • Arginine

What is the purpose of performing acid hydrolysis of proteins at different time points (24, 48, and 72 hours)?

<p>To ensure complete hydrolysis of the peptide bonds (A)</p> Signup and view all the answers

Which of the following amino acids are less destroyed by acid hydrolysis compared to alkaline treatment?

<p>Serine, Threonine, Arginine, and Cysteine (C)</p> Signup and view all the answers

What is the term used for peptide chains with more than 12 but less than 20 residues?

<p>Oligopeptides (C)</p> Signup and view all the answers

How is the term 'polypeptide' used in discussing single polypeptide chains?

<p>Interchangeably with protein (D)</p> Signup and view all the answers

What type of proteins have more than one kind of polypeptide chains?

<p>Heteromultimeric (A)</p> Signup and view all the answers

How are multimeric proteins denoted in terms of composition?

<p>By Greek letters and subscripts (B)</p> Signup and view all the answers

What does an 'α2-type protein' indicate?

<p>Homodimeric structure (D)</p> Signup and view all the answers

Which of the following enzymes is considered relatively nonspecific in cleaving peptide bonds?

<p>Pepsin (A)</p> Signup and view all the answers

Which enzyme is highly specific and cleaves at methionine residues?

<p>Cyanogen bromide (D)</p> Signup and view all the answers

Which enzyme cleaves at arginine residues?

<p>Clostripain (C)</p> Signup and view all the answers

Which of the following enzymes is specific for cleaving at lysine residues?

<p>Endopeptidase Lys-C (C)</p> Signup and view all the answers

Which enzyme cleaves at aspartic acid and glutamic acid residues?

<p>Staphylococcal protease (C)</p> Signup and view all the answers

Which of the following enzymes is found in papaya and causes the hydrolysis of gelatin?

<p>Papain (C)</p> Signup and view all the answers

Which of the following statements is true about the challenges of synthesizing a specific peptide?

<p>All of the above. (D)</p> Signup and view all the answers

What is the purpose of blocking groups in peptide synthesis?

<p>To protect functional groups not involved in the current coupling reaction. (D)</p> Signup and view all the answers

What is a requirement for the blocking groups used in peptide synthesis?

<p>They must be removable under conditions where the newly formed peptide bonds are stable. (A)</p> Signup and view all the answers

What does the text imply about the process of adding each amino acid during peptide synthesis?

<p>It requires several steps involving blocking and deblocking of functional groups. (C)</p> Signup and view all the answers

Which of the following statements is NOT mentioned in the text?

<p>Peptide synthesis can be carried out without any special considerations. (D)</p> Signup and view all the answers

Which of the following is a structural protein that forms inelastic fibrils?

<p>Collagen (D)</p> Signup and view all the answers

What type of proteins are α-Keratins?

<p>Insoluble fibrous proteins (C)</p> Signup and view all the answers

Which of the following is an essential component of ligaments?

<p>Elastin (C)</p> Signup and view all the answers

What type of modules in scaffold proteins bind to proteins with tyrosine residues phosphorylated on its phenolic –OH?

<p>SH2 modules (B)</p> Signup and view all the answers

Which of the following proteins are produced by the lymphocytes of vertebrates?

<p>Immunoglobulins or antibodies (B)</p> Signup and view all the answers

What is the purpose of antifreeze proteins in Arctic and Antarctic fishes?

<p>To protect their blood against freezing in below-zero temperatures (D)</p> Signup and view all the answers

Which of the following is an example of an exploitive protein?

<p>Ricin (C)</p> Signup and view all the answers

What is the function of resilin?

<p>To have exceptional elastic properties (B)</p> Signup and view all the answers

Which of the following proteins is considered an artificial sweetener for human consumption?

<p>Monellin (D)</p> Signup and view all the answers

What type of proteins do certain marine organisms, such as mussels, secrete?

<p>Glue proteins (D)</p> Signup and view all the answers

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