Biology Lecture 1: Microbial Cells

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12 Questions

What is microbiology the study of?

Small living organisms

What percentage of microorganisms are pathogens?

3%

Who coined the term 'animalcules'?

Antony Van Leeuwenhock

What did Louis Pasteur disprove?

Spontaneous generation

What is the term for the theory that diseases are transmitted by microorganisms?

Germ theory of disease

Which of the following is an example of an indigenous microflora?

Microbiota

Who developed pure culture techniques?

Robert Koch

What is the main purpose of Koch's Postulates?

To show that a specific organism causes a specific disease

What is the term for the complete removal of all life forms, including endospores?

Sterilization

Which branch of microbiology deals with the production of drugs, enzymes, and solvents?

Pharmaceutical Microbiology

What is the term for the study of microorganisms in the environment?

Environmental Microbiology

Who isolated bacteria as causative agents for Anthrax?

Robert Koch

Study Notes

Biology of Microbial Cell

  • Biology refers to the study of living organisms, while microbiology studies very small microorganisms or microbes that require a microscope.

Microorganisms (MOs)

  • Include bacteria, algae, protozoa, fungi, and viruses
  • Viruses are infectious agents or particles
  • 3% of microbes are pathogens (disease-causing), while 97% are non-pathogenic
    • 87% of non-pathogens are beneficial and form indigenous microflora or microbiota
    • Microorganisms are ubiquitous (found everywhere)

History of Microbiology

  • Antony Van Leeuwenhock discovered "animalcules" (microorganisms) in 1676
  • Spontaneous Generation theory believed living organisms arise from decomposing matter
    • Contrasted with Biogenesis, which states life arises from pre-existing life

Contributions of Louis Pasteur

  • Showed microbes cause fermentation and spoilage
  • Disproved Spontaneous Generation
  • Developed aseptic techniques (free from pathogenic microorganisms)

Germ Theory of Disease

  • Diseases are transmitted by microbes from a diseased to a healthy person
  • Examples: Diphtheria (Corynebacterium diphtheriae) and Tetanus (Clostridium tetani)

Contributions of Robert Koch

  • Developed solid growth media
  • Introduced pure culture techniques
  • Developed simple stain technique
  • Developed aseptic lab techniques
  • Isolated bacteria as causative agents for Anthrax

Koch's Postulates

  • Series of experimental steps to show a specific organism causes a specific disease

Spores and Sterilization

  • Ferdinand Cohn discovered and described endospores
  • Term "sterile" means complete removal of all life forms, including endospores

Branches of Microbiology

  • Basic Microbiology: classifications, metabolism, nutrition, growth, and requirements
  • Medical Microbiology: Human pathogens
  • Industrial Microbiology: Microorganisms used to obtain industrial products
  • Pharmaceutical Microbiology: Production of drugs, enzymes, solvents, and other products
  • Agricultural Microbiology: Microorganisms as biofertilizers and biocontrol agents of plant pathogens
  • Environmental Microbiology (Microbial Ecology): Microorganisms in pollution, biodegradation, and environmental processes

Introduction to microbiology, studying microorganisms, and their characteristics. Learn about the different types of microorganisms, including bacteria, viruses, and fungi, and their roles in disease and benefits.

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