Biology Competitive Exam 2021-2022

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Questions and Answers

Which drug inhibits DNA gyrase?

  • Chloramphenicol
  • Penicillin
  • Trimethoprim
  • Ciprofloxacin (correct)

Which antimicrobial drug is synthetic?

  • Penicillin
  • Actinomycin
  • Neomycin
  • Sulfanilamide (correct)

Which clinical situation is best treated with a narrow-spectrum antimicrobial drug?

  • Treatment of a polymicrobic mixed infection in the intestine
  • Empiric therapy of pneumonia while waiting for culture results
  • Treatment of strep throat caused by culture identified Streptococcus pyogenes (correct)
  • Prophylaxis against infection after a surgical procedure

Which of the following is not a type of β-lactam antimicrobial?

<p>Glycopeptides (D)</p> Signup and view all the answers

Which resistance mechanism describes the function of β-lactamase?

<p>Drug inactivation (A)</p> Signup and view all the answers

Which of the following is present in prokaryotes but not eukaryotes?

<p>simultaneous transcription and translation (D)</p> Signup and view all the answers

The nitrogen bases in DNA are bonded to the:

<p>deoxyribose (A)</p> Signup and view all the answers

Which statement about IgE is true?

<p>IgE is involved in Type I hypersensitivity reactions. (C)</p> Signup and view all the answers

Which cells are responsible for killing their targets via perforin and granzyme B?

<p>Cytotoxic T cells (D)</p> Signup and view all the answers

A primary role for antibodies in resistance to bacterial infection is:

<p>activation of the alternative complement pathway (D)</p> Signup and view all the answers

Which process involves the uptake of naked DNA from the environment by a bacterial cell?

<p>Transformation (B)</p> Signup and view all the answers

Which type of microorganism uses CO2 as a carbon source and inorganic chemical compounds as an energy and electron source?

<p>Chemolithoautotroph (B)</p> Signup and view all the answers

Which compound lacks the presence of phosphates in the structure of a Gram-positive bacterial cell wall?

<p>Tichuronic acid (C)</p> Signup and view all the answers

Which microorganism type cannot synthesize a growth factor?

<p>Auxoheterotrophic (A)</p> Signup and view all the answers

At what agar concentration does the movement of Proteus bacteria inhibit?

<p>5% (C)</p> Signup and view all the answers

Which type of microorganism is Nitrosomonas?

<p>Chemolithoautotroph (D)</p> Signup and view all the answers

Which one of the following is most responsible for the nature of the lesion on the foot caused by Staphylococcus aureus?

<p>Superantigen toxin (StaphSAg) (D)</p> Signup and view all the answers

What is the best explanation for a negative blood culture in the case of Staphylococcal TSS?

<p>This is typical in staphylococcal TSS. Only the StaphSAg needs to circulate (B)</p> Signup and view all the answers

Which type of enzyme inhibitor affects the enzyme activity by binding to the enzyme at a site other than the active site?

<p>Non-competitive inhibitor (B)</p> Signup and view all the answers

Which method is the best for determining the etiology of a sore throat?

<p>Throat culture (A)</p> Signup and view all the answers

What does virulence refer to?

<p>A term which presumes pathogenicity, but allows expression of degrees from low to extremely high. (A)</p> Signup and view all the answers

Which laboratory test is most likely to confirm the diagnosis of Lyme disease?

<p>Borrelia burgdorferi immunoassay plus immunoblot (B)</p> Signup and view all the answers

An F-pilus is essential for:

<p>Plasmid transfer by conjugation (D)</p> Signup and view all the answers

Which of the following statements about gene expression is false?

<p>Translation begins at a site called a promoter. (C)</p> Signup and view all the answers

Which of the following is NOT characteristic of eukaryotic gene expression?

<p>The mRNA is often polycistronic (D)</p> Signup and view all the answers

What is a distinguishing feature of eukaryotic mRNA?

<p>The presence of a 5' cap. (B)</p> Signup and view all the answers

Which process is not typically associated with bacterial conjugation?

<p>Generalized transduction (A)</p> Signup and view all the answers

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Study Notes

Competitive Exams for the Academic Year 2021-2022

Question 1

  • Chemoautotrophic microorganisms can use CO2 as a source of carbon and inorganic chemicals as a source of energy and electrons.
  • Teichoic acid is a component that lacks phosphate in the cell wall of Gram-positive bacteria.
  • Lipoteichoic acid is a component that lacks phosphate in the cell wall of Gram-positive bacteria.

Question 2

  • Types of inhibitors that affect enzyme activity: uncompetitive, competitive, and noncompetitive inhibitors.

Question 3

  • Nitrosomonas is a chemoautotrophic microorganism.
  • The most responsible factor for the nature of the ulcers on the foot caused by Staphylococcus aureus is Exfoliatin.
  • If the blood culture is negative, the best explanation is that there might be a problem with blood collection.

The Etiology of Sore Throat

  • The best way to determine the etiology of a sore throat is through a throat culture.

Virulence

  • Virulence is the ability of bacteria to cause disease when presented with favorable circumstances.

Lyme Disease

  • The laboratory test that would confirm the diagnosis of Lyme disease is the Borrelia burgdorferi immunoassay.

Spore Formation

  • The stages of spore formation: sporulation, engulfment, fore-spore formation, and spore maturation.

F-pilus

  • An F-pilus is essential for plasmid transfer by conjugation.

Gene Expression

  • False statement: Translation begins at a site called a promoter.
  • True statements: More than one RNA polymerase can be transcribing a specific gene at a given time, More than one ribosome can be translating a specific transcript at a given time, Transcription stops at a site called a terminator, Some amino acids are coded for by more than one codon.

Eukaryotic Gene Expression

  • False statement: The mRNA is often polycistronic.

Multiple Choice

  • The nitrogen bases in DNA are bonded to the deoxyribose.
  • Spliceosomes are present in eukaryotes but not prokaryotes, and simultaneous transcription and translation occur in prokaryotes but not eukaryotes.

Short Answer

  • Conjugation: direct cell-to-cell contact, donor: F+ plasmid, recipient: F- plasmid. Transformation: uptake of free DNA, donor: any DNA source, recipient: competent cells. Transduction: virus-mediated DNA transfer, donor: bacteriophage, recipient: bacterial cells.
  • Selective mediums for Salmonella: LJ medium, XLD agar, and SS agar.
  • True or False: IgE is involved in Type I hypersensitivity reaction, Immune responses are controlled by exclusion of cells from the site of inflammation, Cytotoxic T cells kill targets via perforin and granzyme B, Antibodies activate the alternative complement pathway, Pattern recognition molecules distinguish self from pathogen.

Additional Questions

  • Microbial activity level can be determined by measuring CO2 production, O2 consumption, or ATP production.
  • Carbon cycle in land: photosynthesis, respiration, decomposition. Carbon cycle in microorganisms: photosynthesis, respiration, fermentation.
  • No significant difference between the water cycle in land and the water cycle on the mainland because the water cycle is a continuous process.

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