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Questions and Answers
What is the main function of the umbilical cord's single vein?
What is the main function of the umbilical cord's single vein?
Which type of stem cells is capable of developing into any body cell type?
Which type of stem cells is capable of developing into any body cell type?
What characterizes the rate of blood flow through the umbilical cord at term?
What characterizes the rate of blood flow through the umbilical cord at term?
In which direction does development proceed during zygote growth?
In which direction does development proceed during zygote growth?
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Which primary germ layer is responsible for forming nerve, brain, and skin cells?
Which primary germ layer is responsible for forming nerve, brain, and skin cells?
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How many arteries are present in the umbilical cord?
How many arteries are present in the umbilical cord?
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What is the function of blood withdrawal from the umbilical vein?
What is the function of blood withdrawal from the umbilical vein?
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Which statement about the umbilical cord is true?
Which statement about the umbilical cord is true?
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At what time after fertilization does implantation typically occur?
At what time after fertilization does implantation typically occur?
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Which layer of the inner cell mass is responsible for forming skin and the nervous system?
Which layer of the inner cell mass is responsible for forming skin and the nervous system?
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What term describes the process where the blastocyst attaches to the uterine endometrium?
What term describes the process where the blastocyst attaches to the uterine endometrium?
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What is the primary role of the mesoderm during embryonic development?
What is the primary role of the mesoderm during embryonic development?
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What is a possible consequence of abnormal implantation?
What is a possible consequence of abnormal implantation?
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What happens to the blastocyst on approximately the 4th day after ovulation?
What happens to the blastocyst on approximately the 4th day after ovulation?
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What is the primary function of the trophoblast during implantation?
What is the primary function of the trophoblast during implantation?
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What occurs during the process of invasion in implantation?
What occurs during the process of invasion in implantation?
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What is the function of vernix caseosa during pregnancy?
What is the function of vernix caseosa during pregnancy?
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What indicates the presence of oligohydramnios?
What indicates the presence of oligohydramnios?
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At which week does urine begin to form in the fetus?
At which week does urine begin to form in the fetus?
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What occurs if testosterone is deficient in male fetus development?
What occurs if testosterone is deficient in male fetus development?
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Which factor contributes to the fetus developing temporary passive immunity?
Which factor contributes to the fetus developing temporary passive immunity?
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What is the significance of the primitive tail during fetal development?
What is the significance of the primitive tail during fetal development?
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What condition is indicated when the kidneys are present but not essential in the early weeks of pregnancy?
What condition is indicated when the kidneys are present but not essential in the early weeks of pregnancy?
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Which disease is NOT mentioned as one for which the fetus will receive passive immunity from maternal antibodies?
Which disease is NOT mentioned as one for which the fetus will receive passive immunity from maternal antibodies?
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What is the primary function of Doppler umbilical velocity measurement?
What is the primary function of Doppler umbilical velocity measurement?
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How does B-mode scanning contribute to ultrasonography?
How does B-mode scanning contribute to ultrasonography?
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When can fetal ECGs typically begin to be recorded, according to standard practices?
When can fetal ECGs typically begin to be recorded, according to standard practices?
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What aspect of the placenta is primarily evaluated in placental grading?
What aspect of the placenta is primarily evaluated in placental grading?
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Why is fetal ECG considered inaccurate before the 20th week of pregnancy?
Why is fetal ECG considered inaccurate before the 20th week of pregnancy?
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At which week of development can the baby begin to hear?
At which week of development can the baby begin to hear?
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Which of the following organs begins to take shape by the end of the third week?
Which of the following organs begins to take shape by the end of the third week?
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What significant development occurs during Week 12?
What significant development occurs during Week 12?
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During which week does the fetal heart pump several quarts of blood every day?
During which week does the fetal heart pump several quarts of blood every day?
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What can the baby do by Week 11 of development?
What can the baby do by Week 11 of development?
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What occurs in the baby during the fourth month?
What occurs in the baby during the fourth month?
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What developmental milestone is achieved by the end of Month 4?
What developmental milestone is achieved by the end of Month 4?
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By which week can the baby start to hiccup?
By which week can the baby start to hiccup?
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Study Notes
Implantation
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Implantation occurs approximately 8 to 10 days after fertilization
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The blastocyst sheds the last residues of the corona and zona pellucida after 3 or 4 days of free floating
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The blastocyst brushes against the rich uterine endometrium
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The trophoblast attaches to the surface of the endometrium and settles down into its soft folds
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The inner cell mass forms the fetus
Inner Cell Mass
- The inner cell mass has three layers
- Ectoderm which forms skin and nervous system
- Mesoderm which forms bones, muscles, heart and blood vessels
- Endoderm which forms mucous membranes and glands
Implantation Bleeding
- Maternal blood fills the cavities in the trophoblast just before it is completely covered
- Some blood might leak into the uterine cavity
Amniotic Membrane
- The amniotic membrane has no nerve supply
- It is covered with amniotic fluid
Umbilical cord
- The umbilical cord contains one vein and 2 arteries
- The vein carries blood from the placental villi to the fetus
- The arteries carry blood from the fetus back to the placental villi
- Blood can be withdrawn from the umbilical vein or transfused into the vein during intrauterine life
Fetal Circulation
- The blood flow rate at term is 350 mL/min
- The cord is unlikely to twist or knot due to its rapid flow
Fetal Development
- Development proceeds in a cephalocaudal direction
- Primary germ layers form
- Ectoderm arises from the amniotic cavity
- Entoderm arises from the yolk sac
Fetal Growth
- The fetus has soft downy hairs called lanugo
- The fetus is covered in a cheese-like substance called vernix caseosa which aids lubrication and prevents skin maceration
Immune System
- Maternal IgG antibodies cross the placenta
- They provide temporary passive immunity for the fetus
- This protects the fetus from illnesses like polio, rubella, rubeola, diphtheria, tetanus, infectious parotitis, hep B, and pertussis
- The fetus is susceptible to herpes virus as there is little or no immunity
- The level of immunity peaks at birth and decreases over the next 8 months
- Immunization is started as passive immunity declines
Urinary System
- Kidneys form at the end of week 4
- Urine is formed by week 12
- Urine is excreted into the amniotic fluid by week 16
- The fetus excretes 500 mL of urine/day at term
- Oligohydramnios suggests fetal issues
Fetal Growth Milestones
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Fertilization (day 1) - all human chromosomes are present and unique human life begins
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Day 6: embryo begins implantation in the uterus
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Day 22: heart begins to beat with the child's own blood
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Week 3: backbone, spinal column and nervous system are forming
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Week 4: Length: 0.75 to 1 cm; Weight : 400 mg
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Week 5: eyes, legs, and hands begin to develop
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Week 6: brain waves are detectable; mouth and lips are present; fingernails are forming
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Week 7: eyelids, toes form, nose distinct; the baby is kicking and swimming
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Week 8: every organ is in place, bones begin to replace cartilage, and fingerprints begin to form; Length : 2.5 cm; Weight : 20 g
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Week 9 and 10: teeth begin to form, fingernails develop. The baby can turn his head, and frown; the baby can hiccup
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Weeks 10 and 11: the baby can "breathe" amniotic fluid and urinate; the baby can grasp objects placed in its hand; all organ systems are functioning; The baby has a skeletal structure, nerves, and circulation
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Week 11: the baby can grasp objects placed in its hand; all organ systems are functioning
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Week 12: the baby has all of the parts necessary to experience pain, including nerves, spinal cord, and thalamus; Vocal cords are complete; The baby can suck its thumb; Length : 7 to 8 cm; Weight :45 g; sex is distinguishable by outward appearance; Kidney secretion has begin
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Week 14: the heart pumps several quarts of blood through the body every day; arms and legs are developed
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Week 15: the baby has an adult's taste buds; pupils are capable of reacting to light;
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Month 4: bone marrow is now beginning to form; the heart is pumping 25 quarts of blood a day; the baby will be 8-10 inches in length and will weigh up to half a pound
Ultrasound
- Ultrasound image depends on the type of process used
- B-mode scanning produces a sonogram
- It allows patterns to merge and form a picture
Doppler Umbilical Velocity
- Measures the speed or rate of red blood cells in the uterine and fetal vessels
- Assesses blood flow through uterine blood vessels
- Decreased velocity is an important predictor of poor neonatal outcome
Electrocardiography (ECG)
- Fetal ECGs may be recorded as early as the 11th week of pregnancy
- ECG is inaccurate before the 20th week
- It is rarely used unless specific heart anomaly is suspected
Placental Grading
- Placental grading is based on the amount of calcium deposits in the base of the placenta
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Description
This quiz covers the key concepts related to implantation in human development, including the role of the blastocyst, inner cell mass layers, and the formation of the umbilical cord. Additionally, it addresses implantation bleeding and the amniotic membrane. Test your understanding of these essential biological processes.