Unit 3: Genetics and Cell Division

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Questions and Answers

What is the total number of chromosomes in a human cell?

  • 23
  • 44
  • 22
  • 46 (correct)

The Y chromosome is larger than the X chromosome in males.

False (B)

What are the four types of nitrogenous bases found in DNA?

Guanine, Cytosine, Thymine, Adenine

The backbone of the DNA molecule is made up of alternating __________ and __________.

<p>phosphate groups, sugars</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Karyotype = Diagram of pairs of homologous chromosomes in a cell Codons = Triplets of bases coding for amino acids Autosomal chromosomes = 22 pairs of regular chromosomes Enzymes = Biological catalysts that control chemical reactions</p> Signup and view all the answers

What is the primary role of mRNA in protein synthesis?

<p>To serve as a messenger from DNA to ribosomes (D)</p> Signup and view all the answers

Meiosis results in cells that are genetically identical to the parent cell.

<p>False (B)</p> Signup and view all the answers

What is the term for the structure formed when duplicated chromosomes are joined together?

<p>sister chromatids</p> Signup and view all the answers

During _____ phase of the cell cycle, DNA is synthesized.

<p>S</p> Signup and view all the answers

Match the phases of mitosis with their descriptions:

<p>Prophase = Chromatin condenses into chromosomes Metaphase = Chromosomes align at the equatorial plate Anaphase = Sister chromatids are pulled apart Telophase = Nuclear membrane forms around new nuclei</p> Signup and view all the answers

Which of the following is NOT a cause of mutations?

<p>Growth factors (A)</p> Signup and view all the answers

Chromosomes are formed during interphase.

<p>False (B)</p> Signup and view all the answers

What is the haploid number of chromosomes in humans?

<p>23</p> Signup and view all the answers

A diploid cell contains _____ sets of chromosomes.

<p>two</p> Signup and view all the answers

What is the key to genetics as described in biology?

<p>Central Dogma (B)</p> Signup and view all the answers

How many pairs of homologous chromosomes do humans have?

<p>23 pairs (A)</p> Signup and view all the answers

Meiosis produces diploid daughter cells.

<p>False (B)</p> Signup and view all the answers

What is the term for the fusion of a sperm and an egg?

<p>zygote</p> Signup and view all the answers

During meiosis, _____ cells are produced, which contain half the chromosome number of the original cell.

<p>haploid</p> Signup and view all the answers

Match the term with its definition:

<p>Nondisjunction = Failure of chromosomes to separate properly Euploidy = Correct number of chromosomes Monosomy = Missing a chromosome Polysomy = Having an extra chromosome</p> Signup and view all the answers

What phase of meiosis is primarily responsible for genetic variation through crossing over?

<p>Prophase I (D)</p> Signup and view all the answers

Each haploid daughter cell produced by meiosis contains 23 chromosomes.

<p>True (A)</p> Signup and view all the answers

What are the two processes of meiosis that produce gametes called?

<p>spermatogenesis and oogenesis</p> Signup and view all the answers

The positions where genes are located on homologous chromosomes are called _____.

<p>loci</p> Signup and view all the answers

What is the result of nondisjunction during meiosis?

<p>Additional chromosome(s) (C)</p> Signup and view all the answers

Independent assortment refers to how homologous chromosomes align during meiosis.

<p>True (A)</p> Signup and view all the answers

What type of chromosomes are produced by meiosis?

<p>haploid chromosomes</p> Signup and view all the answers

Meiosis occurs in the _____ tissues of an organism.

<p>reproductive</p> Signup and view all the answers

Match the genetic disorders with their causes:

<p>Down syndrome = Trisomy due to nondisjunction Turner syndrome = Monosomy (XO) Klinefelter syndrome = Extra X chromosome (XXY) Patau syndrome = Trisomy 13</p> Signup and view all the answers

Which scientist is known as the father of modern genetics?

<p>Gregory Mendel (C)</p> Signup and view all the answers

According to Mendel's theory, dominant traits can be expressed regardless of the presence of recessive traits.

<p>True (A)</p> Signup and view all the answers

What is a Punnett square used for?

<p>To determine the combination of recessive and dominant alleles when parents mate.</p> Signup and view all the answers

In genetics, a _____________ is the genetic makeup of an organism.

<p>genotype</p> Signup and view all the answers

What is the result of a monohybrid cross?

<p>Cross involving one trait (D)</p> Signup and view all the answers

Blending theory suggests that offspring are a mix of traits from both parents and that original traits cannot appear again.

<p>True (A)</p> Signup and view all the answers

Explain what incomplete dominance is in genetics.

<p>It is when neither allele completely masks the other, resulting in a phenotype that is a blend of both.</p> Signup and view all the answers

The Law of ____________ states that allele pairs segregate during gamete formation.

<p>Segregation</p> Signup and view all the answers

Match the following concepts with their characteristics:

<p>Codominance = Both alleles are expressed equally Incomplete dominance = A blend of two alleles is expressed True breeding = Organisms consistently produce offspring with the same traits Dihybrid cross = Involves two traits being studied simultaneously</p> Signup and view all the answers

In a dihybrid cross, what does it analyze?

<p>Two traits (A)</p> Signup and view all the answers

Meiosis results in gametes that contain two alleles of each gene.

<p>False (B)</p> Signup and view all the answers

What is the difference between homozygous and heterozygous?

<p>Homozygous refers to having identical alleles for a trait, while heterozygous refers to having two different alleles.</p> Signup and view all the answers

What is the main goal of artificial selection?

<p>To select individuals with desired traits for reproduction (D)</p> Signup and view all the answers

Reproductive cloning results in a genetically identical organism.

<p>True (A)</p> Signup and view all the answers

What is the primary use of therapeutic cloning?

<p>To promote embryonic stem cell growth for medical treatments.</p> Signup and view all the answers

____ is a process that involves pollinating flowers using human intervention.

<p>Artificial pollination</p> Signup and view all the answers

Match the following reproductive technologies with their definitions:

<p>Artificial insemination = Collecting male sperm and inserting it into the female's uterus In Vitro Fertilization = Fertilizing eggs outside the body before implanting them Gene cloning = Isolating and replicating specific genes for use in other organisms Hybridization = Breeding parents from different populations or species</p> Signup and view all the answers

What is one potential drawback of cloning?

<p>Reduced lifespan of the cloned organism (D)</p> Signup and view all the answers

All reproductive technologies enhance genetic diversity.

<p>False (B)</p> Signup and view all the answers

What is one application of gene cloning?

<p>Producing insulin for diabetes treatment.</p> Signup and view all the answers

The process of forming an embryo from a somatic cell and an egg cell is called ______.

<p>Somatic cell nuclear transfer (SCNT)</p> Signup and view all the answers

Match the type of cloning with its description:

<p>Reproductive cloning = Creation of a complete organism Therapeutic cloning = Cloning for stem cell therapy Gene cloning = Isolating specific genes Natural cloning = Occurs without human intervention</p> Signup and view all the answers

Which of the following is a concern regarding genetically modified foods?

<p>Reduction in genetic diversity (C)</p> Signup and view all the answers

Induced pluripotent stem cells (iPSCs) can only be derived from embryonic tissue.

<p>False (B)</p> Signup and view all the answers

What type of cloning makes an organism identical to another?

<p>Reproductive cloning.</p> Signup and view all the answers

The selection of embryos based on desired traits is often referred to as ______.

<p>eugenics</p> Signup and view all the answers

Which of the following is a characteristic of embryonic stem cells?

<p>They can develop into any type of cell (D)</p> Signup and view all the answers

Which flower color results from heterozygous alleles in snapdragons?

<p>Pink (D)</p> Signup and view all the answers

All X-linked traits are dominant.

<p>False (B)</p> Signup and view all the answers

What is the genotype for a roan cow?

<p>CᴿCᵂ</p> Signup and view all the answers

A genetic disorder caused by a dominant allele is called __________.

<p>autosomal dominant disorder</p> Signup and view all the answers

Match the following blood types with their properties:

<p>Type A = Dominant over Type O Type B = Dominant over Type O Type AB = Codominant with Type A and B Type O = Universal donor</p> Signup and view all the answers

What characteristic is true for recessive traits in pedigrees?

<p>They can skip generations. (B)</p> Signup and view all the answers

All genes are inherited independently of one another.

<p>False (B)</p> Signup and view all the answers

What is the main purpose of using a pedigree chart?

<p>To track the inheritance patterns of traits over generations.</p> Signup and view all the answers

The chromosome that typically carries more genes is the __________ chromosome.

<p>X</p> Signup and view all the answers

Match the following traits with their inheritance type:

<p>Polydactyly = Autosomal dominant Color blindness = X-linked recessive Hemophilia = X-linked recessive Cystic fibrosis = Autosomal recessive</p> Signup and view all the answers

What does the symbol 'Cᴿ' represent in snapdragon genetics?

<p>Red allele (C)</p> Signup and view all the answers

The Y chromosome can carry traits that affect fertility in the offspring.

<p>True (A)</p> Signup and view all the answers

What is meant by codominance in genetics?

<p>Both alleles are fully expressed in a heterozygous individual.</p> Signup and view all the answers

Blood type _______ is considered the universal recipient.

<p>AB</p> Signup and view all the answers

How many alleles typically determine blood type?

<p>Three (C)</p> Signup and view all the answers

Flashcards

Heredity

The passing of traits from parents to offspring.

Chromosomes

Thread-like structures in the nucleus of a cell that package DNA.

Karyotype

The arrangement of chromosomes in a cell, showing their pairs.

DNA (Deoxyribonucleic Acid)

A molecule that carries the genetic instructions for building and maintaining an organism, made up of two strands with a ladder-like structure.

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Nucleotide

The basic building block of DNA, consisting of a phosphate group, a sugar, and a nitrogenous base.

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Genes

Segments of DNA located on chromosomes, containing specific instructions for building proteins.

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Locus

The specific location of a gene on a chromosome.

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DNA Replication

The process by which a cell copies its DNA before dividing.

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Transcription

The process of converting DNA information into a messenger molecule (mRNA).

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Translation

The process of using mRNA to build proteins at ribosomes.

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Central Dogma

The central dogma describes the flow of genetic information from DNA to RNA to protein.

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Mutation

A change in the nucleotide sequence of DNA.

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Point Mutation

A type of mutation where one nucleotide is replaced by another.

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Frame-shift Mutation

A type of mutation where a nucleotide is added or deleted, shifting the reading frame of the DNA sequence.

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Mitosis

The process by which a eukaryotic cell divides its genetic material (nucleus) into two identical daughter cells.

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Gametes

Reproductive cells, like sperm and egg cells, that have half the number of chromosomes as a normal body cell.

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Meiosis I

The first division in meiosis, where homologous chromosomes separate.

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Prophase I

The stage in Meiosis I where homologous chromosomes pair up and exchange genetic material.

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Crossing Over

The exchange of genetic material between homologous chromosomes during Prophase I.

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Metaphase I

The stage in Meiosis I where homologous chromosome pairs line up at the center of the cell.

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Anaphase I

The stage in Meiosis I where homologous chromosomes separate and move to opposite poles of the cell.

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Telophase I

The stage in Meiosis I where the cell divides into two daughter cells, each with half the number of chromosomes.

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Meiosis II

The second division in meiosis, where sister chromatids are separated.

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Nondisjunction

The failure of chromosomes to separate properly during meiosis.

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Aneuploidy

A condition where a cell has an abnormal number of chromosomes.

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Monosomy

A condition where a cell has one less chromosome.

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Polysomy

A condition where a cell has one extra chromosome.

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Spermatogenesis

The process of creating sperm cells in the testes.

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Oogenesis

The process of creating egg cells in the ovaries.

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Artificial Selection

Different individuals within a species are selected for desirable traits to reproduce. This process leads to offspring with enhanced characteristics.

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Hybridization

The process of breeding organisms with different traits to create offspring with combined characteristics. It aims to improve the genetic diversity and create organisms with desirable traits.

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Artificial Pollination

A technique involving the direct transfer of pollen from the stamen of one flower to the stigma of another.

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Artificial Insemination

A reproductive technology where sperm is collected from a male and artificially inserted into the female's uterus, bypassing natural mating.

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In Vitro Fertilization (IVF)

An assisted reproductive technology where an egg is fertilized outside the body in a lab setting, followed by the implantation of the embryo into the female's uterus.

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Cloning

The creation of an organism that is genetically identical to another organism.

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Reproductive Cloning

A type of cloning that aims to produce a complete organism genetically identical to the donor organism.

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Therapeutic Cloning

A type of cloning where embryonic stem cells are created from a cloned embryo. These cells are used for research and potential therapeutic applications.

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Gene Cloning (Recombinant DNA)

A process that involves the manipulation of DNA to create new genetic combinations. This technology has various applications, including research, medicine, and agriculture.

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Natural Cloning

A naturally occurring form of cloning where an organism is created from a part of the parent organism, resulting in genetically identical offspring.

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Artificial Twinning

A technique where a fertilized egg is split into two or more embryos, resulting in identical twins or multiples.

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Somatic Cell Nuclear Transfer (SCNT)

A process where the nucleus from a somatic cell (body cell) is transferred into an enucleated egg cell. This results in an embryo with the donor's DNA, leading to the development of a cloned offspring.

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Embryonic Stem Cells

Undifferentiated cells with the ability to develop into any type of cell in the body. They hold potential for treating diseases and injuries.

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Induced Pluripotent Stem Cells (iPSCs)

Cells derived from adult tissues that have been reprogrammed to resemble embryonic stem cells. They have the potential to differentiate into various cell types.

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Eugenics

The application of reproductive technologies to enhance or alter the genetic makeup of organisms, leading to concerns about ethical implications and potential risks.

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Blending Theory

The idea that offspring inherit a blend of traits from both parents, resulting in a mixture of parental characteristics.

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Preformationism (Sperm)

The theory that a complete miniature person exists in the head of a sperm.

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Epigenesis

The theory that an embryo develops in stages, influenced by factors both inside and outside the mother.

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Trait

A specific characteristic or feature that can be passed down from parents to offspring.

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True Breeding

Organisms that consistently produce offspring with the same traits over generations.

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Cross-Pollination

The process where the male gamete (sperm) fertilizes the female gamete (egg), combining their genetic material.

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P Generation

The generation of organisms that are crossed in a breeding experiment.

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F₁ Generation

The offspring resulting from a cross between two individuals in the P generation.

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F₂ Generation

The offspring resulting from a cross between two individuals in the F₁ generation.

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Monohybrid Cross

A cross experiment focusing on a single trait, comparing two individuals with different variations of that trait.

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Alleles

Alternative forms of a gene, responsible for the variations of a trait.

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Punnett Square

A chart that visually shows all possible combinations of alleles an offspring could inherit from its parents.

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Law of Segregation

Pairs of alleles segregate during gamete formation, ensuring each gamete receives only one allele from a pair.

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Dominant Allele

An allele that masks the expression of another allele when present.

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Recessive Allele

An allele whose expression is masked by a dominant allele.

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Codominance

A type of inheritance pattern where both alleles are fully expressed in heterozygous individuals, resulting in a blended phenotype.

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Linked Genes

A type of inheritance where genes located on the same chromosome are inherited together. These genes typically don't assort independently like Mendel's laws suggest.

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Linkage Group

A representation of all genes on a single chromosome.

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Sex-Linked Traits

Traits controlled by genes located on sex chromosomes, typically the X chromosome.

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Hemophilia

A genetic disorder affecting the production of clotting proteins in the blood, resulting in excessive bleeding.

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Pedigree

A diagram that tracks the inheritance of traits through generations of a family, using symbols to represent individuals.

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Multiple Alleles

A type of inheritance where more than two alleles exist for a particular gene, providing more complex variations in traits.

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Blood Type O

Universal blood donors, able to donate to any blood type.

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Blood Types A and B

Universal blood recipients, able to receive blood from any blood type.

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Autosomal Inheritance

The inheritance of traits controlled by genes located on autosomes (non-sex chromosomes).

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Autosomal Dominant Disorder

A genetic disorder where a single copy of the disease-causing allele is enough to cause the disorder.

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Autosomal Recessive Disorder

A genetic disorder where two copies of the disease-causing allele are required to show the disorder.

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Polydactyly

A condition where individuals have extra fingers or toes.

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Albinism

A genetic disorder where individuals lack the ability to produce pigment in their skin, hair, and eyes.

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Study Notes

DNA/RNA

  • Heredity is the passing of traits from parents to offspring.
  • Genetics is the branch of biology studying heredity and variations in inherited traits.
  • Chromosomes are thread-like structures that package DNA in the nucleus.
  • DNA contains instructions for specific types of life.
  • DNA is located inside the nucleus.
  • Chromosomes are inherited in equal halves from each parent.
  • Karyotype: diagram of homologous chromosome pairs in a cell.
  • Humans have 23 homologous pairs (46 total chromosomes).
  • Autosomal chromosomes (22 pairs) determine non-sex traits; sex chromosomes (1 pair) determine sex.
  • XX = female; XY = male.
  • Males' sex chromosomes differ in size (X and Y).
  • DNA (deoxyribonucleic acid) is a double helix structure.
  • DNA determines protein structure.
  • Enzymes are proteins acting as biological catalysts.
  • DNA is made of nucleotides.
  • Nucleotides consist of: a phosphate group, a pentose sugar, and a nitrogenous base.
  • Phosphate and sugar make up the DNA backbone.
  • Bases form the rungs.
  • Four nitrogenous bases: Adenine (A), Thymine (T), Guanine (G), Cytosine (C).
  • Complementary base pairing: A with T; G with C.
  • Codons are sequences of three bases coding for amino acids.
  • Genes are segments of DNA specifying traits and protein production.
  • Proteins create phenotypes.
  • Locus: gene's location on a chromosome.
  • DNA sequence carries information for protein function.
  • Proteins fold into specific 3D shapes.
  • DNA stays in the nucleus; mRNA transports genetic information to ribosomes for protein synthesis.
  • Central dogma: DNA → RNA → protein.
  • RNA differs from DNA: single-stranded, ribose sugar, uracil (U) instead of thymine (T).
  • Mutations: changes in DNA sequence.
  • Point mutations: single base changes.
  • Frame-shift mutations: insertion or deletion of bases.
  • Mutagens: agents causing mutations (e.g., X-rays, chemicals, UV).

Cell Cycle & Mitosis

  • Mitosis: cell division resulting in two identical daughter cells.
  • Human cells have 46 chromosomes (22 pairs of autosomes, 1 pair of sex chromosomes).
  • Karyotype diagrams cells' chromosomes.
  • Cell cycle stages: Interphase (G1, S, G2), Prophase, Metaphase, Anaphase, Telophase, Cytokinesis.
  • Interphase: cell growth and DNA replication.
  • Prophase: chromosomes condense, nuclear membrane breaks down.
  • Metaphase: chromosomes align at the cell's center.
  • Anaphase: sister chromatids separate.
  • Telophase: new nuclear membranes form.
  • Cytokinesis: cytoplasm division.
  • Mitosis functions: growth, cell repair, and maintenance.

Meiosis

  • Diploid (2n): full set of chromosomes.

  • Haploid (n): half a set of chromosomes.

  • Homologous pairs: chromosomes with similar genes.

  • Autosomes: non-sex chromosomes.

  • Meiosis: cell division producing four haploid gametes (sperm or egg).

  • Meiosis I and II: two cell divisions.

  • Meiosis I reduces chromosome number.

  • Meiosis II separates sister chromatids.

  • Spermatogenesis: sperm production.

  • Oogenesis: egg production.

  • Nondisjunction: chromosomes failing to separate properly, leading to abnormal gametes.

  • Nondisjunction in Meiosis I results in homologous chromosomes not separating.

  • Meiosis II nondisjunction results in sister chromatids not separating properly.

  • Nondisjunction causes chromosomal abnormalities (e.g., Down syndrome, Turner syndrome).

  • Nondisjunction can arise from errors in interphase or cell division phases.

  • Variation = genetic diversity in offspring.

  • Meiosis II similar to mitosis (no replication).

  • Crossing over in prophase I shuffles genes/increases diversity.

  • Independent assortment in metaphase I creates variations in gamete combinations.

  • Random fertilization further increases genetic variation in offspring.

Reproductive Technologies

  • Reproductive technologies: enhance or alter reproduction.
  • Artificial selection: choosing organisms with desirable traits for breeding.
  • Hybridization: crossing different populations/species to create offspring.
  • Artificial insemination: introducing male sperm into female reproductive tract.
  • In Vitro Fertilization (IVF): egg fertilization outside the body.
  • Cloning: creating genetically identical copies.
  • Reproductive cloning: creating a whole new organism.
  • Methods: artificial twinning, somatic cell nuclear transfer (SCNT).
  • Therapeutic cloning: creating stem cells for medical purposes.
  • Induced pluripotent stem cells (iPSCs): reprogram adult cells into embryonic-like stem cells.
  • Gene cloning: inserting genes into other organisms to produce desired proteins.
  • Example usage: creating insulin for diabetics or pesticides for crops.

Patterns of Inheritance

  • Pangenesis: incorrect theory that body parts contribute genes.

  • Epigenesis: development in stages.

  • Blending theory: offspring traits are a mix of parental traits.

  • Mendel: father of modern genetics.

  • Pea plants used for genetic studies.

  • Traits: specific characteristics.

  • True-breeding: organisms consistently showing the same trait across generations.

  • Cross-pollination: controlled fertilization.

  • Law of Segregation: alleles separate during gamete formation, with each gamete receiving only one.

  • Principle of Dominance: the dominant allele masks the recessive allele’s expression.

  • Genotype: genetic makeup (e.g., HH, Hh, hh).

  • Phenotype: observable trait (e.g., tall, short).

  • Complete dominance: one allele completely masks another.

  • Incomplete dominance: heterozygote displays an intermediate trait.

  • Codominance: both alleles are fully expressed in heterozygotes.

  • Dihybrid cross: examining inheritance of two traits.

  • Law of Independent Assortment: alleles of different genes segregate independently into gametes.

Sex-Linked Traits & Multiple Alleles

  • Sex-linked traits: traits controlled by genes on sex chromosomes (X and Y).
  • X-linked traits more common (due to X chromosome's larger size).
  • Y-linked traits passed from fathers to sons only.
  • Multiple alleles: more than two alleles available for a gene.
  • Blood type example: different genotypes result in various phenotypes (A, B, AB, O).
  • Rh factor: presence or absence of a protein in blood (positive/negative).

Pedigrees

  • Pedigree: chart demonstrating inheritance patterns of traits through generations.
  • Autosomal inheritance: inheritance determined by genes on non-sex chromosomes.
  • Autosomal dominant: disorder appears in each generation.
  • Autosomal recessive: disorder can skip generations.
  • Pedigree analysis used to understand inheritance.
  • Pedigrees help identify inheritance patterns, calculate probabilities of offspring having a trait, and identify carriers.

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