Podcast
Questions and Answers
What is the total number of chromosomes in a human cell?
What is the total number of chromosomes in a human cell?
- 23
- 44
- 22
- 46 (correct)
The Y chromosome is larger than the X chromosome in males.
The Y chromosome is larger than the X chromosome in males.
False (B)
What are the four types of nitrogenous bases found in DNA?
What are the four types of nitrogenous bases found in DNA?
Guanine, Cytosine, Thymine, Adenine
The backbone of the DNA molecule is made up of alternating __________ and __________.
The backbone of the DNA molecule is made up of alternating __________ and __________.
Match the following terms with their descriptions:
Match the following terms with their descriptions:
What is the primary role of mRNA in protein synthesis?
What is the primary role of mRNA in protein synthesis?
Meiosis results in cells that are genetically identical to the parent cell.
Meiosis results in cells that are genetically identical to the parent cell.
What is the term for the structure formed when duplicated chromosomes are joined together?
What is the term for the structure formed when duplicated chromosomes are joined together?
During _____ phase of the cell cycle, DNA is synthesized.
During _____ phase of the cell cycle, DNA is synthesized.
Match the phases of mitosis with their descriptions:
Match the phases of mitosis with their descriptions:
Which of the following is NOT a cause of mutations?
Which of the following is NOT a cause of mutations?
Chromosomes are formed during interphase.
Chromosomes are formed during interphase.
What is the haploid number of chromosomes in humans?
What is the haploid number of chromosomes in humans?
A diploid cell contains _____ sets of chromosomes.
A diploid cell contains _____ sets of chromosomes.
What is the key to genetics as described in biology?
What is the key to genetics as described in biology?
How many pairs of homologous chromosomes do humans have?
How many pairs of homologous chromosomes do humans have?
Meiosis produces diploid daughter cells.
Meiosis produces diploid daughter cells.
What is the term for the fusion of a sperm and an egg?
What is the term for the fusion of a sperm and an egg?
During meiosis, _____ cells are produced, which contain half the chromosome number of the original cell.
During meiosis, _____ cells are produced, which contain half the chromosome number of the original cell.
Match the term with its definition:
Match the term with its definition:
What phase of meiosis is primarily responsible for genetic variation through crossing over?
What phase of meiosis is primarily responsible for genetic variation through crossing over?
Each haploid daughter cell produced by meiosis contains 23 chromosomes.
Each haploid daughter cell produced by meiosis contains 23 chromosomes.
What are the two processes of meiosis that produce gametes called?
What are the two processes of meiosis that produce gametes called?
The positions where genes are located on homologous chromosomes are called _____.
The positions where genes are located on homologous chromosomes are called _____.
What is the result of nondisjunction during meiosis?
What is the result of nondisjunction during meiosis?
Independent assortment refers to how homologous chromosomes align during meiosis.
Independent assortment refers to how homologous chromosomes align during meiosis.
What type of chromosomes are produced by meiosis?
What type of chromosomes are produced by meiosis?
Meiosis occurs in the _____ tissues of an organism.
Meiosis occurs in the _____ tissues of an organism.
Match the genetic disorders with their causes:
Match the genetic disorders with their causes:
Which scientist is known as the father of modern genetics?
Which scientist is known as the father of modern genetics?
According to Mendel's theory, dominant traits can be expressed regardless of the presence of recessive traits.
According to Mendel's theory, dominant traits can be expressed regardless of the presence of recessive traits.
What is a Punnett square used for?
What is a Punnett square used for?
In genetics, a _____________ is the genetic makeup of an organism.
In genetics, a _____________ is the genetic makeup of an organism.
What is the result of a monohybrid cross?
What is the result of a monohybrid cross?
Blending theory suggests that offspring are a mix of traits from both parents and that original traits cannot appear again.
Blending theory suggests that offspring are a mix of traits from both parents and that original traits cannot appear again.
Explain what incomplete dominance is in genetics.
Explain what incomplete dominance is in genetics.
The Law of ____________ states that allele pairs segregate during gamete formation.
The Law of ____________ states that allele pairs segregate during gamete formation.
Match the following concepts with their characteristics:
Match the following concepts with their characteristics:
In a dihybrid cross, what does it analyze?
In a dihybrid cross, what does it analyze?
Meiosis results in gametes that contain two alleles of each gene.
Meiosis results in gametes that contain two alleles of each gene.
What is the difference between homozygous and heterozygous?
What is the difference between homozygous and heterozygous?
What is the main goal of artificial selection?
What is the main goal of artificial selection?
Reproductive cloning results in a genetically identical organism.
Reproductive cloning results in a genetically identical organism.
What is the primary use of therapeutic cloning?
What is the primary use of therapeutic cloning?
____ is a process that involves pollinating flowers using human intervention.
____ is a process that involves pollinating flowers using human intervention.
Match the following reproductive technologies with their definitions:
Match the following reproductive technologies with their definitions:
What is one potential drawback of cloning?
What is one potential drawback of cloning?
All reproductive technologies enhance genetic diversity.
All reproductive technologies enhance genetic diversity.
What is one application of gene cloning?
What is one application of gene cloning?
The process of forming an embryo from a somatic cell and an egg cell is called ______.
The process of forming an embryo from a somatic cell and an egg cell is called ______.
Match the type of cloning with its description:
Match the type of cloning with its description:
Which of the following is a concern regarding genetically modified foods?
Which of the following is a concern regarding genetically modified foods?
Induced pluripotent stem cells (iPSCs) can only be derived from embryonic tissue.
Induced pluripotent stem cells (iPSCs) can only be derived from embryonic tissue.
What type of cloning makes an organism identical to another?
What type of cloning makes an organism identical to another?
The selection of embryos based on desired traits is often referred to as ______.
The selection of embryos based on desired traits is often referred to as ______.
Which of the following is a characteristic of embryonic stem cells?
Which of the following is a characteristic of embryonic stem cells?
Which flower color results from heterozygous alleles in snapdragons?
Which flower color results from heterozygous alleles in snapdragons?
All X-linked traits are dominant.
All X-linked traits are dominant.
What is the genotype for a roan cow?
What is the genotype for a roan cow?
A genetic disorder caused by a dominant allele is called __________.
A genetic disorder caused by a dominant allele is called __________.
Match the following blood types with their properties:
Match the following blood types with their properties:
What characteristic is true for recessive traits in pedigrees?
What characteristic is true for recessive traits in pedigrees?
All genes are inherited independently of one another.
All genes are inherited independently of one another.
What is the main purpose of using a pedigree chart?
What is the main purpose of using a pedigree chart?
The chromosome that typically carries more genes is the __________ chromosome.
The chromosome that typically carries more genes is the __________ chromosome.
Match the following traits with their inheritance type:
Match the following traits with their inheritance type:
What does the symbol 'Cᴿ' represent in snapdragon genetics?
What does the symbol 'Cᴿ' represent in snapdragon genetics?
The Y chromosome can carry traits that affect fertility in the offspring.
The Y chromosome can carry traits that affect fertility in the offspring.
What is meant by codominance in genetics?
What is meant by codominance in genetics?
Blood type _______ is considered the universal recipient.
Blood type _______ is considered the universal recipient.
How many alleles typically determine blood type?
How many alleles typically determine blood type?
Flashcards
Heredity
Heredity
The passing of traits from parents to offspring.
Chromosomes
Chromosomes
Thread-like structures in the nucleus of a cell that package DNA.
Karyotype
Karyotype
The arrangement of chromosomes in a cell, showing their pairs.
DNA (Deoxyribonucleic Acid)
DNA (Deoxyribonucleic Acid)
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Nucleotide
Nucleotide
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Genes
Genes
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Locus
Locus
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DNA Replication
DNA Replication
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Transcription
Transcription
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Translation
Translation
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Central Dogma
Central Dogma
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Mutation
Mutation
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Point Mutation
Point Mutation
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Frame-shift Mutation
Frame-shift Mutation
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Mitosis
Mitosis
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Gametes
Gametes
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Meiosis I
Meiosis I
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Prophase I
Prophase I
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Crossing Over
Crossing Over
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Metaphase I
Metaphase I
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Anaphase I
Anaphase I
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Telophase I
Telophase I
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Meiosis II
Meiosis II
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Nondisjunction
Nondisjunction
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Aneuploidy
Aneuploidy
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Monosomy
Monosomy
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Polysomy
Polysomy
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Spermatogenesis
Spermatogenesis
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Oogenesis
Oogenesis
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Artificial Selection
Artificial Selection
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Hybridization
Hybridization
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Artificial Pollination
Artificial Pollination
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Artificial Insemination
Artificial Insemination
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In Vitro Fertilization (IVF)
In Vitro Fertilization (IVF)
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Cloning
Cloning
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Reproductive Cloning
Reproductive Cloning
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Therapeutic Cloning
Therapeutic Cloning
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Gene Cloning (Recombinant DNA)
Gene Cloning (Recombinant DNA)
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Natural Cloning
Natural Cloning
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Artificial Twinning
Artificial Twinning
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Somatic Cell Nuclear Transfer (SCNT)
Somatic Cell Nuclear Transfer (SCNT)
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Embryonic Stem Cells
Embryonic Stem Cells
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Induced Pluripotent Stem Cells (iPSCs)
Induced Pluripotent Stem Cells (iPSCs)
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Eugenics
Eugenics
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Blending Theory
Blending Theory
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Preformationism (Sperm)
Preformationism (Sperm)
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Epigenesis
Epigenesis
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Trait
Trait
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True Breeding
True Breeding
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Cross-Pollination
Cross-Pollination
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P Generation
P Generation
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F₁ Generation
F₁ Generation
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F₂ Generation
F₂ Generation
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Monohybrid Cross
Monohybrid Cross
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Alleles
Alleles
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Punnett Square
Punnett Square
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Law of Segregation
Law of Segregation
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Dominant Allele
Dominant Allele
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Recessive Allele
Recessive Allele
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Codominance
Codominance
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Linked Genes
Linked Genes
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Linkage Group
Linkage Group
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Sex-Linked Traits
Sex-Linked Traits
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Hemophilia
Hemophilia
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Pedigree
Pedigree
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Multiple Alleles
Multiple Alleles
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Blood Type O
Blood Type O
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Blood Types A and B
Blood Types A and B
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Autosomal Inheritance
Autosomal Inheritance
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Autosomal Dominant Disorder
Autosomal Dominant Disorder
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Autosomal Recessive Disorder
Autosomal Recessive Disorder
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Polydactyly
Polydactyly
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Albinism
Albinism
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Study Notes
DNA/RNA
- Heredity is the passing of traits from parents to offspring.
- Genetics is the branch of biology studying heredity and variations in inherited traits.
- Chromosomes are thread-like structures that package DNA in the nucleus.
- DNA contains instructions for specific types of life.
- DNA is located inside the nucleus.
- Chromosomes are inherited in equal halves from each parent.
- Karyotype: diagram of homologous chromosome pairs in a cell.
- Humans have 23 homologous pairs (46 total chromosomes).
- Autosomal chromosomes (22 pairs) determine non-sex traits; sex chromosomes (1 pair) determine sex.
- XX = female; XY = male.
- Males' sex chromosomes differ in size (X and Y).
- DNA (deoxyribonucleic acid) is a double helix structure.
- DNA determines protein structure.
- Enzymes are proteins acting as biological catalysts.
- DNA is made of nucleotides.
- Nucleotides consist of: a phosphate group, a pentose sugar, and a nitrogenous base.
- Phosphate and sugar make up the DNA backbone.
- Bases form the rungs.
- Four nitrogenous bases: Adenine (A), Thymine (T), Guanine (G), Cytosine (C).
- Complementary base pairing: A with T; G with C.
- Codons are sequences of three bases coding for amino acids.
- Genes are segments of DNA specifying traits and protein production.
- Proteins create phenotypes.
- Locus: gene's location on a chromosome.
- DNA sequence carries information for protein function.
- Proteins fold into specific 3D shapes.
- DNA stays in the nucleus; mRNA transports genetic information to ribosomes for protein synthesis.
- Central dogma: DNA → RNA → protein.
- RNA differs from DNA: single-stranded, ribose sugar, uracil (U) instead of thymine (T).
- Mutations: changes in DNA sequence.
- Point mutations: single base changes.
- Frame-shift mutations: insertion or deletion of bases.
- Mutagens: agents causing mutations (e.g., X-rays, chemicals, UV).
Cell Cycle & Mitosis
- Mitosis: cell division resulting in two identical daughter cells.
- Human cells have 46 chromosomes (22 pairs of autosomes, 1 pair of sex chromosomes).
- Karyotype diagrams cells' chromosomes.
- Cell cycle stages: Interphase (G1, S, G2), Prophase, Metaphase, Anaphase, Telophase, Cytokinesis.
- Interphase: cell growth and DNA replication.
- Prophase: chromosomes condense, nuclear membrane breaks down.
- Metaphase: chromosomes align at the cell's center.
- Anaphase: sister chromatids separate.
- Telophase: new nuclear membranes form.
- Cytokinesis: cytoplasm division.
- Mitosis functions: growth, cell repair, and maintenance.
Meiosis
-
Diploid (2n): full set of chromosomes.
-
Haploid (n): half a set of chromosomes.
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Homologous pairs: chromosomes with similar genes.
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Autosomes: non-sex chromosomes.
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Meiosis: cell division producing four haploid gametes (sperm or egg).
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Meiosis I and II: two cell divisions.
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Meiosis I reduces chromosome number.
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Meiosis II separates sister chromatids.
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Spermatogenesis: sperm production.
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Oogenesis: egg production.
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Nondisjunction: chromosomes failing to separate properly, leading to abnormal gametes.
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Nondisjunction in Meiosis I results in homologous chromosomes not separating.
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Meiosis II nondisjunction results in sister chromatids not separating properly.
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Nondisjunction causes chromosomal abnormalities (e.g., Down syndrome, Turner syndrome).
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Nondisjunction can arise from errors in interphase or cell division phases.
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Variation = genetic diversity in offspring.
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Meiosis II similar to mitosis (no replication).
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Crossing over in prophase I shuffles genes/increases diversity.
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Independent assortment in metaphase I creates variations in gamete combinations.
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Random fertilization further increases genetic variation in offspring.
Reproductive Technologies
- Reproductive technologies: enhance or alter reproduction.
- Artificial selection: choosing organisms with desirable traits for breeding.
- Hybridization: crossing different populations/species to create offspring.
- Artificial insemination: introducing male sperm into female reproductive tract.
- In Vitro Fertilization (IVF): egg fertilization outside the body.
- Cloning: creating genetically identical copies.
- Reproductive cloning: creating a whole new organism.
- Methods: artificial twinning, somatic cell nuclear transfer (SCNT).
- Therapeutic cloning: creating stem cells for medical purposes.
- Induced pluripotent stem cells (iPSCs): reprogram adult cells into embryonic-like stem cells.
- Gene cloning: inserting genes into other organisms to produce desired proteins.
- Example usage: creating insulin for diabetics or pesticides for crops.
Patterns of Inheritance
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Pangenesis: incorrect theory that body parts contribute genes.
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Epigenesis: development in stages.
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Blending theory: offspring traits are a mix of parental traits.
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Mendel: father of modern genetics.
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Pea plants used for genetic studies.
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Traits: specific characteristics.
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True-breeding: organisms consistently showing the same trait across generations.
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Cross-pollination: controlled fertilization.
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Law of Segregation: alleles separate during gamete formation, with each gamete receiving only one.
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Principle of Dominance: the dominant allele masks the recessive allele’s expression.
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Genotype: genetic makeup (e.g., HH, Hh, hh).
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Phenotype: observable trait (e.g., tall, short).
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Complete dominance: one allele completely masks another.
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Incomplete dominance: heterozygote displays an intermediate trait.
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Codominance: both alleles are fully expressed in heterozygotes.
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Dihybrid cross: examining inheritance of two traits.
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Law of Independent Assortment: alleles of different genes segregate independently into gametes.
Sex-Linked Traits & Multiple Alleles
- Sex-linked traits: traits controlled by genes on sex chromosomes (X and Y).
- X-linked traits more common (due to X chromosome's larger size).
- Y-linked traits passed from fathers to sons only.
- Multiple alleles: more than two alleles available for a gene.
- Blood type example: different genotypes result in various phenotypes (A, B, AB, O).
- Rh factor: presence or absence of a protein in blood (positive/negative).
Pedigrees
- Pedigree: chart demonstrating inheritance patterns of traits through generations.
- Autosomal inheritance: inheritance determined by genes on non-sex chromosomes.
- Autosomal dominant: disorder appears in each generation.
- Autosomal recessive: disorder can skip generations.
- Pedigree analysis used to understand inheritance.
- Pedigrees help identify inheritance patterns, calculate probabilities of offspring having a trait, and identify carriers.
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