biochemistry midterms
506 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the role of a catalyst in a chemical reaction?

  • It speeds up the reaction without being consumed. (correct)
  • It lowers the reaction temperature required.
  • It is used up during the reaction.
  • It increases the activation energy needed.

What does a holoenzyme consist of?

  • An apoenzyme and a cofactor. (correct)
  • A metal ion and a coenzyme.
  • An enzyme and a substrate.
  • Only the apoenzyme.

Which type of enzymes require metal for their function?

  • Metalloenzymes. (correct)
  • Coenzymes.
  • Catalytic enzymes.
  • Allosteric enzymes.

What distinguishes low-density lipoproteins (LDLs) from high-density lipoproteins (HDLs)?

<p>LDLs transport cholesterol from the liver to various body tissues. (C)</p> Signup and view all the answers

Which of the following statements about statins is true?

<p>They are widely prescribed to lower cholesterol levels. (B)</p> Signup and view all the answers

Which bile salt contains glycine as its alipathic group?

<p>Glycocholate (C)</p> Signup and view all the answers

Which type of fats are predominantly saturated?

<p>Fats (A)</p> Signup and view all the answers

What is the primary characteristic of oils compared to fats?

<p>Oils are predominantly unsaturated (D)</p> Signup and view all the answers

Which of the following is considered a 'good fat'?

<p>Polyunsaturated fats (A), Omega-3 fatty acids (D)</p> Signup and view all the answers

What type of chemical reaction is hydrolysis of triacylglycerols?

<p>Reverse of esterification (A)</p> Signup and view all the answers

Which of the following describes waxes?

<p>They are water-repellent and hydrophobic (D)</p> Signup and view all the answers

What process is responsible for the solidification of fats from liquid oils?

<p>Hydrogenation (A)</p> Signup and view all the answers

Which hormones are classified as Vitamin D Hormones?

<p>Vit.D2 (A)</p> Signup and view all the answers

Which of the following fats is categorized as a 'bad fat'?

<p>Saturated fats (D)</p> Signup and view all the answers

What is the typical state of fats at room temperature?

<p>Solid or semisolid (D)</p> Signup and view all the answers

What is the primary function of messenger RNA (mRNA)?

<p>To carry information specifying the amino acid sequence of a protein to the ribosome (A)</p> Signup and view all the answers

Which statement about translation is accurate?

<p>Only mRNA is translated to protein (B)</p> Signup and view all the answers

What is a codon?

<p>A sequence of three mRNA nucleotides that codes for a specific amino acid (D)</p> Signup and view all the answers

What initiates the process of translation?

<p>AUG codon (A)</p> Signup and view all the answers

During DNA replication, what occurs to the parent DNA molecule?

<p>It unwinds and serves as a template for new strands (A)</p> Signup and view all the answers

What ensures the new DNA molecules are identical to the original set?

<p>DNA proofreading mechanisms (A)</p> Signup and view all the answers

Which of the following codons is a stop codon?

<p>UAA (C)</p> Signup and view all the answers

What is the result of a frameshift mutation?

<p>It causes a protein to be synthesized with an altered sequence. (C)</p> Signup and view all the answers

Which type of mutation involves the addition or loss of DNA bases?

<p>Frameshift mutation (A)</p> Signup and view all the answers

In what way does a deletion mutation affect the chromosome?

<p>It removes or loses a chromosomal segment. (A)</p> Signup and view all the answers

What is the primary goal of the polymerase chain reaction (PCR)?

<p>To create many copies of a specific DNA region. (B)</p> Signup and view all the answers

What occurs during the annealing step of the PCR process?

<p>Primers bind to the original DNA strands. (A)</p> Signup and view all the answers

What type of lipids are known as energy-storage lipids?

<p>Triacylglycerols (D)</p> Signup and view all the answers

What is the process of reversing a segment within a chromosome called?

<p>Inversion (D)</p> Signup and view all the answers

Which kind of lipids are classified as membrane lipids?

<p>Phospholipids (C)</p> Signup and view all the answers

What defines a translocation mutation?

<p>It moves a segment from one chromosome to a nonhomologous chromosome. (D)</p> Signup and view all the answers

What is the primary function of simple glycerides?

<p>Energy storage (A)</p> Signup and view all the answers

Which of the following statements about eicosanoids is true?

<p>They are derived from arachidonic acid. (C)</p> Signup and view all the answers

What is the parent structure of sphingolipids?

<p>Sphingosine (A)</p> Signup and view all the answers

How many fatty acids esterify with glycerol to form a triglyceride?

<p>3 (D)</p> Signup and view all the answers

What characterizes a mixed triacylglycerol?

<p>It has different R groups or fatty acids attached. (A)</p> Signup and view all the answers

What is the energy yield of triglycerides compared to carbohydrates or proteins?

<p>9 cal/g (D)</p> Signup and view all the answers

What effect do eicosanoids typically have in the body?

<p>Mediating inflammation (D)</p> Signup and view all the answers

Which type of triglyceride has all the same fatty acids attached?

<p>Simple Triacylglycerol (C)</p> Signup and view all the answers

What is a characteristic feature of eicosanoids?

<p>Short lifespan (D)</p> Signup and view all the answers

Which statement about DHA is true?

<p>It plays a role in neural and visual function development. (C)</p> Signup and view all the answers

What role does helicase play in DNA replication?

<p>It unwinds the DNA helix and separates the strands. (A)</p> Signup and view all the answers

Which enzyme is responsible for adding RNA primers during DNA replication?

<p>Primase (D)</p> Signup and view all the answers

Which process ensures the continuity of the lagging strand during DNA replication?

<p>Synthesis of Okazaki fragments (B)</p> Signup and view all the answers

What does ligase do in the process of DNA replication?

<p>Joins DNA segments on discontinuous strands (D)</p> Signup and view all the answers

How would you describe the relationship between adenine and thymine according to Chargaff's rule?

<p>They are equivalent in quantity. (A)</p> Signup and view all the answers

Which of the following correctly describes transcription?

<p>It copies DNA into RNA. (B)</p> Signup and view all the answers

What determines the property of an amino acid?

<p>The side chain (R) (A)</p> Signup and view all the answers

Under what conditions do amino acids exist as zwitterions?

<p>Normal cellular conditions with no net charge (D)</p> Signup and view all the answers

Which statement about the stereochemistry of amino acids is true?

<p>Proteins are generally composed of L-amino acids (C)</p> Signup and view all the answers

How does the pH of a solution affect the structure of amino acids?

<p>Increasing pH causes zwitterions to lose a proton (A)</p> Signup and view all the answers

What is the fundamental role of proteins in cellular functions?

<p>They are involved in virtually all cell functions (B)</p> Signup and view all the answers

Which type of mutation involves the reversal of a segment within a chromosome?

<p>Inversion (B)</p> Signup and view all the answers

During which step of PCR are primers attached to the original DNA strands?

<p>Annealing (A)</p> Signup and view all the answers

Which mutation involves the loss of a chromosomal segment?

<p>Deletion (B)</p> Signup and view all the answers

What characterizes energy-storage lipids?

<p>They are primarily triacylglycerols. (D)</p> Signup and view all the answers

What is the outcome when a segment of DNA is duplicated?

<p>It may attach to a sister chromatid. (C)</p> Signup and view all the answers

What is the main purpose of the polymerase chain reaction?

<p>To produce specific DNA regions. (A)</p> Signup and view all the answers

Which type of mutation refers to the movement of a DNA segment to a nonhomologous chromosome?

<p>Translocation (A)</p> Signup and view all the answers

Which lipids are classified as membrane lipids?

<p>Phospholipids (C)</p> Signup and view all the answers

What is the primary function of antioxidants such as vitamin C and vitamin E in food preservation?

<p>They prevent undesirable oxidation processes. (B)</p> Signup and view all the answers

What occurs during the hydrogenation of triacylglycerols?

<p>Carbon–carbon single bonds are formed. (B)</p> Signup and view all the answers

What role do cofactors play in the activity of enzymes?

<p>They enhance or assist the catalytic properties of enzymes. (A)</p> Signup and view all the answers

What is unique about enzymes in relation to their substrates?

<p>Enzymes possess active sites for specific substrate interaction. (C)</p> Signup and view all the answers

What is an apoenzyme?

<p>An inactive form of an enzyme without its cofactor. (B)</p> Signup and view all the answers

Which statement best describes saturated fatty acids in the context of hydrogenation?

<p>They are produced by the reduction of unsaturated fatty acids. (A)</p> Signup and view all the answers

How do enzymes affect the activation energy of a reaction?

<p>They lower the activation energy required for the reaction. (C)</p> Signup and view all the answers

What are the potential effects of rancidity in fats and oils?

<p>Objectionable odors and loss of nutritional quality. (A)</p> Signup and view all the answers

What effect does hydrogenation have on unsaturated fatty acids?

<p>It alters them into saturated fatty acids. (C)</p> Signup and view all the answers

Which type of fatty acid is typically formed during the hydrogenation process?

<p>Saturated fatty acid. (C)</p> Signup and view all the answers

What is the primary mode of action of statins?

<p>Inhibition of HMG-CoA reductase (A)</p> Signup and view all the answers

Which enzyme is responsible for the decarboxylation of pyruvate?

<p>Pyruvate decarboxylase (D)</p> Signup and view all the answers

Which classification of enzymes catalyzes oxidation-reduction reactions?

<p>Oxidoreductases (D)</p> Signup and view all the answers

What type of reaction do isomerases facilitate?

<p>Transfer of functional groups within the same molecule (B)</p> Signup and view all the answers

Which enzyme is an example of an oxidoreductase that transfers H+?

<p>Lactate dehydrogenase (B)</p> Signup and view all the answers

Which enzyme catalyzes the removal of a carboxyl group from pyruvate?

<p>DOPA decarboxylase (A)</p> Signup and view all the answers

What role do reductases play in biochemical reactions?

<p>They reduce substrates by transferring electrons (A)</p> Signup and view all the answers

What is a function of transferases in the body?

<p>They transfer functional or chemical groups (D)</p> Signup and view all the answers

Which example best illustrates the function of an isomerase?

<p>Conversion of D-alanine to L-alanine (C)</p> Signup and view all the answers

Which statement about the action of dehydrogenases is true?

<p>They introduce double bonds by removing hydrogen atoms. (A)</p> Signup and view all the answers

What term describes the presence of a carboxyl group in fatty acids?

<p>Hydrophilicity (B)</p> Signup and view all the answers

How does the degree of saturation affect melting point and boiling point of fatty acids?

<p>Saturated fatty acids have higher melting points. (C)</p> Signup and view all the answers

At what chain length do fatty acids typically become soluble in water?

<p>Up to 10 carbons (B)</p> Signup and view all the answers

What effect does the presence of a double bond have on the physical properties of fatty acids?

<p>Lowers melting point (D)</p> Signup and view all the answers

Which type of fatty acid is generally more soluble in water?

<p>Unsaturated fatty acid (C)</p> Signup and view all the answers

What structural characteristic do most fatty acids share?

<p>An even number of carbons (B)</p> Signup and view all the answers

How does solubility change as the length of the fatty acid chain increases?

<p>Solubility decreases with more carbons (A)</p> Signup and view all the answers

What is the primary function of lyases in biochemical reactions?

<p>Cleave C-C, C-O, or C-N bonds without hydrolysis or oxidation (C)</p> Signup and view all the answers

Which model of enzyme-substrate binding considers three-dimensional flexibility?

<p>Induced fit model (B)</p> Signup and view all the answers

What is a specific characteristic of competitive inhibitors?

<p>Compete with the substrate for the active site (A)</p> Signup and view all the answers

Which type of lyase is responsible for the removal of water from a substrate?

<p>Dehydratase (D)</p> Signup and view all the answers

What effect does a non-competitive inhibitor have on an enzyme's Km and Vmax?

<p>Keeps Km unchanged and decreases Vmax (C)</p> Signup and view all the answers

What component is essential for the structural role of phospholipids in biological membranes?

<p>Polar and nonpolar portions (A)</p> Signup and view all the answers

Which of the following is a characteristic of glycolipids?

<p>Have a recognition site on cell surfaces (B)</p> Signup and view all the answers

Which lipid serves as a major component of the myelin sheath in nerve tissues?

<p>Ceramide derivatives (D)</p> Signup and view all the answers

What is the parent structure of phosphoglycerides?

<p>Phosphatidic acid (A)</p> Signup and view all the answers

What is a common function of membrane lipids?

<p>Structural framework (B)</p> Signup and view all the answers

Which statement correctly describes the composition of phospholipids?

<p>Contain a fatty acid, alcohol, and a phosphate group (D)</p> Signup and view all the answers

What are ceramides primarily composed of?

<p>Fatty acids and sphingosine (B)</p> Signup and view all the answers

In cell membranes, what structural arrangement do phospholipids form?

<p>Lipid bilayers (B)</p> Signup and view all the answers

What role do glycolipids play regarding blood types?

<p>They anchor blood type carbohydrates in the RBC membrane (A)</p> Signup and view all the answers

What is a characteristic of fats compared to oils?

<p>Predominantly saturated (D)</p> Signup and view all the answers

Which process breaks down triacylglycerols into mono- or diacylglycerol and fatty acids?

<p>Hydrolysis (C)</p> Signup and view all the answers

How are waxes generally described in terms of their chemical properties?

<p>Hydrophobic and water-repellent (A)</p> Signup and view all the answers

Which type of fat can be classified as both good and bad?

<p>Polyunsaturated fats (A)</p> Signup and view all the answers

What is the state of oils typically at room temperature?

<p>Liquids (D)</p> Signup and view all the answers

Which vitamin D hormone is primarily found in plant tissue?

<p>Vitamin D2 (B)</p> Signup and view all the answers

Which chemical reaction involves the addition of a fatty acid to a glycerol molecule?

<p>Esterification (C)</p> Signup and view all the answers

Which fatty acid types are categorized as important 'good fats'?

<p>Omega-3 and omega-6 (D)</p> Signup and view all the answers

What is the source distinction for fats and oils?

<p>Fats primarily come from animal sources, while oils come from plants (C)</p> Signup and view all the answers

What is the combination that forms a glucocerebroside?

<p>Ceramide + glucose (D)</p> Signup and view all the answers

Which of the following compounds is a glycolipid?

<p>Ganglioside (C)</p> Signup and view all the answers

What type of linkage connects NANA to the oligosaccharide in gangliosides?

<p>Alpha linkage (C)</p> Signup and view all the answers

What is the primary role of sphingomyelin in the body?

<p>Used primarily in nerve tissue (D)</p> Signup and view all the answers

Which statement about cholesterol is true?

<p>It has a cyclopentanoperhydrophenanthrene structure. (A)</p> Signup and view all the answers

Which of the following acts as an emulsifier for fatty acids?

<p>Bile acids (B)</p> Signup and view all the answers

What percentage of all lipids in humans are sphingolipids?

<p>25% (D)</p> Signup and view all the answers

Which molecule is primarily associated with the myelin sheath?

<p>Sphingomyelin (A)</p> Signup and view all the answers

What characteristic of phospholipids allows them to form cell membranes?

<p>Hydrophilic heads and hydrophobic tails (C)</p> Signup and view all the answers

What is the key structural feature of bile acids?

<p>Derived from cholesterol (B)</p> Signup and view all the answers

What is the primary reason that longer hydrocarbon chains in fatty acids reduce solubility in water?

<p>They are primarily made of hydrophobic components. (D)</p> Signup and view all the answers

Which type of fatty acid is solid at room temperature?

<p>Saturated fatty acids (D)</p> Signup and view all the answers

What effect do double bonds have on the solubility of fatty acids?

<p>They shorten the hydrocarbon chain. (A)</p> Signup and view all the answers

Which group in fatty acids is responsible for their hydrophilic nature?

<p>Carboxyl group (C)</p> Signup and view all the answers

What is a characteristic of low-density lipoproteins (LDLs)?

<p>They are linked to higher heart disease risk. (C)</p> Signup and view all the answers

How does the chain length affect the solubility of short-chain fatty acids in water?

<p>Shorter chains are highly soluble. (C)</p> Signup and view all the answers

What property do unsaturated fatty acids generally have due to their structural configuration?

<p>They are liquid at room temperature. (A)</p> Signup and view all the answers

What happens to zwitterions when the pH of the solution is increased?

<p>They lose a proton (D)</p> Signup and view all the answers

Which type of amino acids are primarily utilized in protein assembly?

<p>L-amino acids (C)</p> Signup and view all the answers

What effect does high salt concentration have on enzymes?

<p>It can denature the enzyme (D)</p> Signup and view all the answers

What do animals require as essential fatty acids in their diets?

<p>N-6 and N-3 fatty acids (B)</p> Signup and view all the answers

Which animals lack the ability to carry out chain elongation and desaturation?

<p>Carnivores like cats and some fish (A)</p> Signup and view all the answers

What structure is a derivative of a 20-carbon fatty acid, which contains a cyclopentane ring and oxygen-containing functional groups?

<p>Prostaglandins (A)</p> Signup and view all the answers

What is a characteristic feature of cis fatty acids compared to trans fatty acids?

<p>Kinked structure affecting their physical properties (D)</p> Signup and view all the answers

How do essential fatty acids (EFA) generally affect body functions?

<p>Promote smooth muscle relaxation and contraction (B)</p> Signup and view all the answers

Which of the following statements best describes butyric acid?

<p>Present in coconut oil (A)</p> Signup and view all the answers

What role do prostaglandins play in the body?

<p>They increase pain sensation and inflammation (D)</p> Signup and view all the answers

What significant effect does aspirin have related to prostaglandins?

<p>Inhibits their synthesis (A)</p> Signup and view all the answers

What is true about the relationship between carbon chain length and the melting point of fatty acids?

<p>Double bonds lower melting points regardless of chain length (B)</p> Signup and view all the answers

What is a characteristic of saturated fats?

<p>They are typically solid or semisolid at room temperature. (B)</p> Signup and view all the answers

What is one of the processes involved in the chemical reactions of triacylglycerols?

<p>Saponification (D)</p> Signup and view all the answers

What is a property of waxes?

<p>They are hydrophobic and do not dissolve in water. (B)</p> Signup and view all the answers

Which type of fatty acids are omega-3 and omega-6 classified as?

<p>Good fats (B)</p> Signup and view all the answers

Which reaction is the reverse of the esterification reaction involving triacylglycerols?

<p>Hydrolysis (B)</p> Signup and view all the answers

What distinguishes fats from oils regarding their physical state?

<p>Fats are predominantly saturated; oils are predominantly unsaturated. (A)</p> Signup and view all the answers

Which of the following processes relates to breaking ester bonds in triacylglycerols?

<p>Saponification (C)</p> Signup and view all the answers

What is the principal function of simple glycerides?

<p>Energy storage (B)</p> Signup and view all the answers

What characterizes eicosanoids in terms of their physiological effects?

<p>They exert effects at very low concentrations. (D)</p> Signup and view all the answers

How many fatty acids can esterify with one glycerol molecule to form a triglyceride?

<p>Three fatty acids (D)</p> Signup and view all the answers

What type of triacylglycerol has different fatty acids attached to the glycerol?

<p>Mixed Triacylglycerol (B)</p> Signup and view all the answers

Which of the following statements about DHA is accurate?

<p>DHA is required for proper neural and visual function development. (C)</p> Signup and view all the answers

What is the primary characteristic of triacylglycerols in terms of their composition?

<p>They are composed of fatty acids and glycerol. (D)</p> Signup and view all the answers

What role do eicosanoids have in inflammation?

<p>They mediate inflammatory responses. (D)</p> Signup and view all the answers

What distinguishes a simple triacylglycerol from a mixed triacylglycerol?

<p>Simple contains a single type of fatty acid. (D)</p> Signup and view all the answers

Which bile salt has taurine as its alipathic group?

<p>Taurocholate (A)</p> Signup and view all the answers

What characterizes waxes?

<p>They have a protective coating property. (A)</p> Signup and view all the answers

What type of fats are primarily derived from plant sources?

<p>Polyunsaturated fats (B)</p> Signup and view all the answers

During the hydrolysis of triacylglycerols, what is produced?

<p>Mono- or diacylglycerol and fatty acids (D)</p> Signup and view all the answers

What role do codons play in the process of translation?

<p>They signal the start or end of protein synthesis (D)</p> Signup and view all the answers

During DNA replication, what happens to the base sequences?

<p>They must be identical to the original set (A)</p> Signup and view all the answers

Which of the following describes a codon?

<p>A sequence of three RNA nucleotides coding for an amino acid (B)</p> Signup and view all the answers

Which statement about DNA replication is true?

<p>It results in two identical daughter DNA molecules (B)</p> Signup and view all the answers

What is the function of tRNA during translation?

<p>To carry amino acids to the ribosome (C)</p> Signup and view all the answers

What is the significance of the AUG codon?

<p>It is a start codon that codes for methionine (A)</p> Signup and view all the answers

What are the hydrophilic components of fatty acids?

<p>Carboxyl group (B)</p> Signup and view all the answers

How does the length of the hydrocarbon chain affect solubility in water?

<p>Longer chains decrease solubility (B)</p> Signup and view all the answers

What is the state of saturated fatty acids at room temperature?

<p>Solid (C)</p> Signup and view all the answers

What effect does an increasing number of double bonds in fatty acids have?

<p>Increases water solubility (B)</p> Signup and view all the answers

What characteristic differentiates short chain fatty acids in terms of solubility?

<p>Slightly soluble in water (D)</p> Signup and view all the answers

What type of cholesterol is associated with saturated fatty acids?

<p>Low-density lipoprotein (LDL) (D)</p> Signup and view all the answers

Which of the following statements about unsaturated fatty acids is true?

<p>They contain multiple double bonds (C)</p> Signup and view all the answers

Why are long-chain fatty acids less soluble in water?

<p>They have fewer double bonds (D)</p> Signup and view all the answers

Which factor primarily affects fatty acids' solubility in water?

<p>Hydrocarbon chain length (C)</p> Signup and view all the answers

What is the main reason for eating before taking aspirin?

<p>To neutralize stomach acids (A)</p> Signup and view all the answers

What is the role of thromboxanes in the body?

<p>To promote platelet aggregation (D)</p> Signup and view all the answers

Why are trans fatty acids considered harmful?

<p>They facilitate blood clotting (A)</p> Signup and view all the answers

What are leukotrienes derived from?

<p>Arachidonic acid (C)</p> Signup and view all the answers

What effect does LTC4 and LTD4 have on the body?

<p>Increase bronchoconstriction (D)</p> Signup and view all the answers

Which of the following distinguishes prostaglandins from thromboxanes?

<p>Prostaglandins have conjugated double bonds (A)</p> Signup and view all the answers

What is the characteristic structure of prostanoic acid?

<p>A cyclic ether ring with oxygen-containing groups (A)</p> Signup and view all the answers

What potential risk does aspirin pose to patients with dengue fever?

<p>It causes gastrointestinal bleeding (B)</p> Signup and view all the answers

Which fatty acid is a precursor for eicosanoids?

<p>Arachidonic acid (A)</p> Signup and view all the answers

What does IL-1, IL-2, and IFN-γ promote in the immune response?

<p>T-cell proliferation (A)</p> Signup and view all the answers

What is the main structural role of phospholipids in biological membranes?

<p>They form the lipid bilayer that composes cell membranes (D)</p> Signup and view all the answers

What are glycolipids primarily composed of?

<p>A fatty acid, sphingosine, and a carbohydrate (A)</p> Signup and view all the answers

Which component is a part of the basic structure of phospholipids?

<p>Phosphatidic acid (B)</p> Signup and view all the answers

What function do some lipids serve on the surface of a cell?

<p>Recognition sites for cellular interaction (B)</p> Signup and view all the answers

What distinguishes sphingomyelin from other types of lipids?

<p>It is formed from ceramide and phosphorylcholine (C)</p> Signup and view all the answers

What is the primary role of ceramide derivatives in the human body?

<p>Insulatory function in nerve tissues (B)</p> Signup and view all the answers

How are lipids characterized to ensure they can form membranes?

<p>They must contain both polar and nonpolar portions (C)</p> Signup and view all the answers

What is a major component of the cellular membranes formed by phospholipids?

<p>Lipid bilayers (B)</p> Signup and view all the answers

What role does the carbohydrate play in glycolipids?

<p>Facilitates cellular recognition and interaction (A)</p> Signup and view all the answers

What type of lipids primarily constitute the myelin sheath surrounding neurons?

<p>Sphingomyelin (D)</p> Signup and view all the answers

What is the primary structural feature of an alpha helix?

<p>Spiral shape stabilized by hydrogen bonds (D)</p> Signup and view all the answers

Which type of proteins are generally water-soluble and compact in shape?

<p>Enzymes and hormones (A)</p> Signup and view all the answers

What is the primary function of chaperones in protein folding?

<p>They assist proteins to fold correctly (A)</p> Signup and view all the answers

Where is deoxyribonucleic acid (DNA) primarily found?

<p>Within the cell nucleus (A)</p> Signup and view all the answers

What distinguishes peptides from proteins in terms of amino acid count?

<p>Peptides contain less than 50 amino acids (A)</p> Signup and view all the answers

What structural characteristic distinguishes ribose from deoxyribose sugar?

<p>Ribose has an OH group on the second carbon (C)</p> Signup and view all the answers

Which structure is formed by the interactions of multiple polypeptide chains?

<p>Quaternary structure (D)</p> Signup and view all the answers

Which nitrogenous base pair forms two hydrogen bonds?

<p>Adenine and Thymine (B)</p> Signup and view all the answers

How many hydrogen bonds connect Cytosine and Guanine in DNA?

<p>Three (B)</p> Signup and view all the answers

What is the primary function of RNA within the cell?

<p>To synthesize proteins (B)</p> Signup and view all the answers

What type of bonding connects the two strands of DNA?

<p>Hydrogen Bonding (B)</p> Signup and view all the answers

Which statement accurately describes the composition of a nucleotide?

<p>Nitrogen base, sugar, and phosphate (B)</p> Signup and view all the answers

What makes fatty acids amphipathic?

<p>They contain both hydrophilic and hydrophobic groups. (B)</p> Signup and view all the answers

What effect does increasing the number of double bonds in fatty acids have on solubility?

<p>It increases solubility in water. (C)</p> Signup and view all the answers

Which statement about saturated fatty acids is true?

<p>They are associated with bad cholesterol. (D)</p> Signup and view all the answers

What describes the solubility characteristics of short-chain fatty acids?

<p>They are sparingly soluble in water. (A)</p> Signup and view all the answers

How does the length of the hydrocarbon chain affect the solubility of fatty acids?

<p>Longer chains decrease water solubility. (C)</p> Signup and view all the answers

Which fatty acid characteristic is linked with being solid at room temperature?

<p>High level of saturation. (B)</p> Signup and view all the answers

Why are longer hydrocarbon chains associated with lower solubility in water?

<p>They have fewer functional groups. (C)</p> Signup and view all the answers

What contributes to the solid nature of saturated fatty acids at room temperature?

<p>The absence of double bonds. (A)</p> Signup and view all the answers

Which property is characteristic of unsaturated fatty acids compared to saturated fatty acids?

<p>They tend to be more soluble in water. (B)</p> Signup and view all the answers

What type of bonds do lyases cleave?

<p>C-C, C-O, or C-N bonds (A)</p> Signup and view all the answers

What is the primary characteristic of the lock and key model of enzyme activity?

<p>Enzyme is rigid and does not change (D)</p> Signup and view all the answers

Which enzyme is an example of a dehydratase?

<p>Carbonic anhydrase (C)</p> Signup and view all the answers

How does a competitive inhibitor affect enzyme activity?

<p>Competes with substrate for the active site (B)</p> Signup and view all the answers

What is the effect of non-competitive inhibitors on enzyme activity?

<p>Change the Vmax without affecting Km (B)</p> Signup and view all the answers

What distinguishes the induced fit model from the lock and key model?

<p>Enzyme shape is altered after substrate binding (C)</p> Signup and view all the answers

Which of the following reactions is catalyzed by a deaminase?

<p>Removal of NH3 from a substrate (C)</p> Signup and view all the answers

What is the role of hydratases in biochemical reactions?

<p>Addition of H2O to a substrate (C)</p> Signup and view all the answers

Which inhibitor acts by binding to a site other than the active site?

<p>Non-competitive inhibitor (D)</p> Signup and view all the answers

What type of enzyme is a decarboxylase responsible for?

<p>Removal of CO2 from a substrate (A)</p> Signup and view all the answers

Which type of molecule binds to enzymes and reduces their activity?

<p>Inhibitors (B)</p> Signup and view all the answers

What happens to a zwitterion when the pH of the solution is lowered?

<p>It gains a proton (B)</p> Signup and view all the answers

Which amino acid stereochemistry is predominantly found in proteins?

<p>L-amino acids (B)</p> Signup and view all the answers

What can high salt concentration do to an enzyme?

<p>Denature it (D)</p> Signup and view all the answers

How many amino acids are known to occur in nature?

<p>700 (A)</p> Signup and view all the answers

What is the significance of the isoelectric point for amino acids?

<p>It is the point where amino acids have no net charge. (A)</p> Signup and view all the answers

What is the primary linkage between amino acids in proteins?

<p>Peptide bond (D)</p> Signup and view all the answers

What does changing the pH of a solution containing amino acids affect?

<p>The charge of the zwitterions (D)</p> Signup and view all the answers

What is the primary function of ribosomal RNA (rRNA)?

<p>To form the functional ribosome (D)</p> Signup and view all the answers

What occurs during transcription in protein synthesis?

<p>DNA is copied into RNA (B)</p> Signup and view all the answers

Which type of RNA is responsible for bringing amino acids to the ribosome?

<p>Transfer RNA (tRNA) (B)</p> Signup and view all the answers

In which process are genetic messages decoded to build proteins?

<p>Translation (A)</p> Signup and view all the answers

What is the most abundant type of RNA found in cells?

<p>Ribosomal RNA (rRNA) (A)</p> Signup and view all the answers

What does the Central Dogma of molecular biology describe?

<p>The flow of genetic information in cells (D)</p> Signup and view all the answers

Which of the following best describes what occurs during replication?

<p>Identical copies of DNA are made (C)</p> Signup and view all the answers

Which of the following correctly defines a metalloenzyme?

<p>An enzyme that requires metal ions in its structure. (C)</p> Signup and view all the answers

What role do coenzymes play in enzymatic reactions?

<p>They are organic molecules that facilitate enzyme activity. (D)</p> Signup and view all the answers

How do low-density lipoproteins (LDLs) function in the body?

<p>They carry excess cholesterol from the liver to other parts of the body. (A)</p> Signup and view all the answers

Which characteristic describes a catalyst in chemical reactions?

<p>It speeds up the reaction without being used up in the process. (D)</p> Signup and view all the answers

What is the primary role of statins in the body?

<p>To lower cholesterol levels in the bloodstream. (B)</p> Signup and view all the answers

What is the basic structure found in all phosphoglycerides?

<p>Phosphatidic acid (C)</p> Signup and view all the answers

Which function do glycolipids primarily serve in the cell membrane?

<p>Recognition sites (B)</p> Signup and view all the answers

What type of lipid is used primarily in nerve tissues as myelin sheath?

<p>Sphingomyelin (C)</p> Signup and view all the answers

Which of the following characteristics must lipids have to be suitable for forming bilayers?

<p>Nonpolar tail and polar head (A)</p> Signup and view all the answers

What component is combined with sphingosine to produce ceramide?

<p>Fatty acid (C)</p> Signup and view all the answers

Which characteristic defines fatty acids as amphipathic?

<p>Presence of both hydrophilic and hydrophobic groups (A)</p> Signup and view all the answers

Which of the following describes the composition of phospholipids?

<p>Fatty acid, alcohol, and phosphatidic acid (D)</p> Signup and view all the answers

Which lipid type contributes significantly to the structure of membranes?

<p>Phospholipids (C)</p> Signup and view all the answers

What kind of lipid is sphingomyelin classified as?

<p>Sphingophospholipid (D)</p> Signup and view all the answers

What primarily influences the solubility of fatty acids in water?

<p>The length of the hydrocarbon chain (A), The type of fatty acid (saturated vs unsaturated) (C)</p> Signup and view all the answers

Why are short-chain fatty acids considered sparingly soluble in water?

<p>They have polar carboxylic acid groups (B)</p> Signup and view all the answers

What is the primary function of lipids in a biological membrane?

<p>Structural integrity and insulation (B)</p> Signup and view all the answers

What type of fatty acids are generally solid at room temperature?

<p>Saturated fatty acids (D)</p> Signup and view all the answers

Which component anchors blood type carbohydrates into red blood cell membranes?

<p>Glycolipids (D)</p> Signup and view all the answers

Which fatty acids carry bad cholesterol in the body?

<p>Saturated fatty acids (A)</p> Signup and view all the answers

How does the structure of unsaturated fatty acids differ from saturated fatty acids?

<p>Unsaturated fatty acids contain fewer hydrogen atoms (C)</p> Signup and view all the answers

What is the solubility trend for fatty acids with increased hydrocarbon chain length?

<p>Solubility in water decreases (D)</p> Signup and view all the answers

What is a consequence of having fewer double bonds in fatty acids?

<p>Higher melting point (B)</p> Signup and view all the answers

What is the component that, when added to ceramide, forms glucocerebroside?

<p>Glucose (B)</p> Signup and view all the answers

Which type of linkage connects oligosaccharides to ceramide in gangliosides?

<p>Beta linkages (D)</p> Signup and view all the answers

Which molecule primarily forms the myelin sheath in nerve tissue?

<p>Sphingomyelin (C)</p> Signup and view all the answers

What type of sugar forms a sulfatide when combined with ceramide?

<p>Sulfated sugar (C)</p> Signup and view all the answers

Which structural feature is NOT associated with cholesterol?

<p>Presence of nitrogen (B)</p> Signup and view all the answers

Which hormone class originates from cholesterol in the adrenal cortex?

<p>Steroid hormones (B)</p> Signup and view all the answers

What role do bile acids play in the body?

<p>Emulsify fatty acids (C)</p> Signup and view all the answers

Which part of the phospholipid is hydrophilic?

<p>Ionic head groups (A)</p> Signup and view all the answers

What is the loss of the double bond in ring B of cholesterol characteristic of?

<p>Conversion to bile acids (D)</p> Signup and view all the answers

What is a significant property of sphingolipids within human cells?

<p>They are a major component of nerve tissue (B)</p> Signup and view all the answers

What is a frameshift mutation?

<p>The addition or loss of DNA bases that alters a gene's reading frame (C)</p> Signup and view all the answers

Which of the following describes the process of translocation in genetics?

<p>A segment from one chromosome is moved to a nonhomologous chromosome (D)</p> Signup and view all the answers

What occurs during the denaturation step of PCR?

<p>The DNA strands are separated into single strands (A)</p> Signup and view all the answers

What is the purpose of annealing in the PCR process?

<p>To allow primers to bind to the template DNA (B)</p> Signup and view all the answers

Which type of mutation involves the loss of a chromosomal segment?

<p>Deletion (A)</p> Signup and view all the answers

Which of the following lipids is classified as an energy-storage lipid?

<p>Triacylglycerols (C)</p> Signup and view all the answers

What characterizes an inversion mutation?

<p>A segment within a chromosome is reversed (C)</p> Signup and view all the answers

Which bile salt is characterized by having taurine as its alipathic group?

<p>Taurocholate (C)</p> Signup and view all the answers

Which type of fat is typically found in plant sources and is liquid at room temperature?

<p>Unsaturated fats (B)</p> Signup and view all the answers

What chemical reaction describes the breaking of ester bonds in triacylglycerols?

<p>Hydrolysis (A)</p> Signup and view all the answers

What is the primary feature of waxes in terms of their interaction with water?

<p>Hydrophobic (B)</p> Signup and view all the answers

Which process involves the reverse action of esterification when dealing with triacylglycerols?

<p>Hydrolysis (C)</p> Signup and view all the answers

Which type of fat includes omega 3 and 6 fatty acids and is considered beneficial?

<p>Polyunsaturated fats (C)</p> Signup and view all the answers

Which statement accurately describes the state of oils at room temperature?

<p>Liquid (D)</p> Signup and view all the answers

Which of the following is a common source of triglycerides?

<p>Animal products (D)</p> Signup and view all the answers

What type of fats tend to be categorized as 'bad fats'?

<p>Trans fats (B)</p> Signup and view all the answers

What type of bond is broken during the hydrolysis of triacylglycerols?

<p>Ester bonds (C)</p> Signup and view all the answers

What property of waxes makes them suitable as insulators?

<p>Low thermal conductivity (A)</p> Signup and view all the answers

Which of the following is a typical state of waxes at room temperature?

<p>Solid (C)</p> Signup and view all the answers

Which enzyme family is primarily responsible for catalyzing oxidation reactions in biological systems?

<p>Oxidoreductases (A)</p> Signup and view all the answers

What is a common application of lanolin, a type of wax?

<p>Protective baby skin treatment (B)</p> Signup and view all the answers

What is a primary characteristic of waxes in terms of chemical stability?

<p>Relatively chemically stable (B)</p> Signup and view all the answers

What type of chemical reaction results in the production of aldhehydes or carboxylic acids from alkenes?

<p>Oxidation (B)</p> Signup and view all the answers

What do saponification reactions produce when triacylglycerols undergo hydrolysis in a basic solution?

<p>Glycerol and salt of fatty acid (D)</p> Signup and view all the answers

What defines the role of enzymes as catalysts in biological systems?

<p>They are not consumed during the reactions (B)</p> Signup and view all the answers

Which of the following waxes is secreted by the sebaceous glands of the skin?

<p>Sebum (D)</p> Signup and view all the answers

What is the metabolic state of an enzyme when it is combined with a cofactor?

<p>Holoenzyme (C)</p> Signup and view all the answers

What property of waxes allows them to function as lubricants?

<p>Lubricating properties (B)</p> Signup and view all the answers

Which type of molecules can act as coenzymes in enzyme reactions?

<p>Organic molecules derived from vitamins (D)</p> Signup and view all the answers

What is the primary role of low-density lipoproteins (LDLs) in the body?

<p>Transport cholesterol from the liver to tissues (A)</p> Signup and view all the answers

What is a common function of statins?

<p>Inhibit cholesterol production in the liver (A)</p> Signup and view all the answers

Which of the following best describes a catalyst in a chemical reaction?

<p>A chemical that lowers the activation energy (B)</p> Signup and view all the answers

What is a characteristic of butyric acid?

<p>It is predominant in coconut oil. (C)</p> Signup and view all the answers

Which essential fatty acids do animals require in their diets?

<p>n-6 and n-3 fatty acids (D)</p> Signup and view all the answers

Which animals are unable to perform chain elongation and desaturation of fatty acids?

<p>Cats and some fish (B)</p> Signup and view all the answers

What may prostaglandins contribute to in the body?

<p>Increasing inflammation responses (B)</p> Signup and view all the answers

What distinguishes cis fatty acids from trans fatty acids?

<p>Trans fatty acids have double bonds in a specific configuration. (B)</p> Signup and view all the answers

What is one effect of essential fatty acids in the animal diet?

<p>They are necessary for prostaglandin production. (A)</p> Signup and view all the answers

How do the boiling and melting points of fatty acids generally change with chain length?

<p>Longer chains have higher boiling and melting points. (A)</p> Signup and view all the answers

What role does aspirin play in the body during fever?

<p>It inhibits the enzyme needed to make prostaglandins. (D)</p> Signup and view all the answers

Which statement accurately describes the effect of double bonds on fatty acids?

<p>More double bonds lower the melting point. (D)</p> Signup and view all the answers

What type of mutation results from the addition or loss of DNA bases, altering a gene's reading frame?

<p>Frameshift mutation (C)</p> Signup and view all the answers

Which process occurs first during the polymerase chain reaction (PCR)?

<p>Denaturation of the template (D)</p> Signup and view all the answers

What is a characteristic of a deletion mutation?

<p>It removes a chromosomal segment. (C)</p> Signup and view all the answers

What characterizes emulsification lipids?

<p>They assist in the digestion of fats. (A)</p> Signup and view all the answers

Which statement correctly describes an inversion mutation?

<p>It reverses a segment within a chromosome. (D)</p> Signup and view all the answers

What does not contribute to the classification of lipids based on solubility?

<p>Functionality of the lipid (D)</p> Signup and view all the answers

What is the primary outcome of a frameshift mutation?

<p>The resulting protein is often nonfunctional. (B)</p> Signup and view all the answers

What is a characteristic of saturated fatty acids compared to unsaturated fatty acids?

<p>Higher melting point (D)</p> Signup and view all the answers

What factor primarily affects the solubility of fatty acids in water?

<p>Length of the hydrocarbon chain (B)</p> Signup and view all the answers

Why are fatty acids with double bonds more soluble in water than their saturated counterparts?

<p>Double bonds create bends in the chain (C)</p> Signup and view all the answers

What generally occurs to the melting point of a fatty acid as the number of carbon atoms increases?

<p>It increases (A)</p> Signup and view all the answers

For fatty acids with fewer than 10 carbon atoms, what is true regarding their solubility?

<p>They are highly soluble in water (B)</p> Signup and view all the answers

What determines the degree of saturation in fatty acids?

<p>The presence of double bonds (D)</p> Signup and view all the answers

Which statement correctly describes the hydrophilic nature of fatty acids?

<p>The carboxyl group is hydrophilic (A)</p> Signup and view all the answers

What is the solubility trend of fatty acids as the chain length increases beyond 10 carbon atoms?

<p>Decreases and can become insoluble (B)</p> Signup and view all the answers

What distinguishes straight-chain fatty acids from branched-chain fatty acids in terms of melting point?

<p>Straight chains have higher melting points due to closer packing (C)</p> Signup and view all the answers

What defines a metalloenzyme?

<p>Enzymes that use metal ions as a cofactor (A)</p> Signup and view all the answers

What is the role of coenzymes in enzymatic reactions?

<p>To assist in the activation of substrate molecules (A)</p> Signup and view all the answers

Which statement about cholesterol transport is accurate?

<p>High levels of HDLs are associated with lower heart disease risk. (A)</p> Signup and view all the answers

What distinguishes a holoenzyme from an apoenzyme?

<p>An apoenzyme includes its cofactor. (A)</p> Signup and view all the answers

What is the primary function of a catalyst in a chemical reaction?

<p>To lower the activation energy needed for the reaction (A)</p> Signup and view all the answers

What effect does increasing the chain length of fatty acids have on the melting temperature?

<p>Increases melting temperature (A)</p> Signup and view all the answers

Which type of fatty acid contains only one double bond?

<p>Monounsaturated fatty acid (C)</p> Signup and view all the answers

What is the impact of unsaturation on the melting temperature of fatty acids?

<p>Decreases melting temperature (A)</p> Signup and view all the answers

Which of the following fatty acids is classified as saturated?

<p>Stearic acid (18:0) (D)</p> Signup and view all the answers

What is the primary reason that saturated fatty acids have higher melting temperatures than unsaturated fatty acids?

<p>More Van der Waals forces (A)</p> Signup and view all the answers

How is a polyunsaturated fatty acid characterized?

<p>Two or more double bonds (D)</p> Signup and view all the answers

Which chain length category includes fatty acids with 6 to 12 carbon atoms?

<p>Medium chain (C)</p> Signup and view all the answers

What characteristic of fatty acid molecules is affected by their degree of saturation?

<p>Melting temperature (A)</p> Signup and view all the answers

Which of the following fatty acids is expected to have the lowest melting point?

<p>Arachidonic acid (20:4) (A)</p> Signup and view all the answers

How do Van der Waals forces contribute to the properties of fatty acids?

<p>They increase melting temperature. (B)</p> Signup and view all the answers

What is the primary reason that short chain fatty acids are sparingly soluble in water?

<p>They have a polar carboxylic acid group. (B)</p> Signup and view all the answers

How does the length of the hydrocarbon chain affect the solubility of fatty acids in water?

<p>Longer chains decrease solubility. (C)</p> Signup and view all the answers

What effect do an increasing number of double bonds have on the solubility of fatty acids?

<p>They increase the solubility. (B)</p> Signup and view all the answers

Which group is responsible for the amphipathic nature of fatty acids?

<p>Hydrophilic carboxyl group. (B)</p> Signup and view all the answers

Which of the following statements is true regarding the solubility of fatty acids?

<p>Unsaturated fatty acids are generally more soluble than saturated. (A)</p> Signup and view all the answers

What type of cholesterol is primarily associated with saturated fatty acids?

<p>Low-density lipoprotein (LDL). (C)</p> Signup and view all the answers

What characterizes the state of fatty acids with longer hydrocarbon chains?

<p>They tend to be solid at room temperature. (C)</p> Signup and view all the answers

What property do fatty acids exhibit due to their amphipathic nature?

<p>They can form micelles in aqueous solutions. (D)</p> Signup and view all the answers

What primarily determines the difference in solubility between saturated and unsaturated fatty acids?

<p>The number of double bonds present. (D)</p> Signup and view all the answers

What characteristic is true for butyric acid?

<p>It is present in coconut oil. (C)</p> Signup and view all the answers

Which statement about cis and trans fatty acids is accurate?

<p>Cis fatty acids generally have lower melting points than trans fatty acids. (C)</p> Signup and view all the answers

What function do prostaglandins serve in the body?

<p>They control body temperature. (D)</p> Signup and view all the answers

Which animals cannot carry out chain elongation and desaturation of fatty acids?

<p>Cats and some fish (D)</p> Signup and view all the answers

What distinguishes deoxyribose from ribose in nucleic acids?

<p>Deoxyribose is characterized by the absence of an oxygen atom at C2. (B)</p> Signup and view all the answers

Which statement accurately describes the pairing of nitrogenous bases in DNA?

<p>Cytosine pairs with Guanine through three hydrogen bonds. (B)</p> Signup and view all the answers

Which of the following best describes the structural characteristics of DNA?

<p>DNA consists of two anti-parallel polynucleotide strands. (D)</p> Signup and view all the answers

Which of the following correctly describes a difference between purines and pyrimidines?

<p>Purines are characterized by a double ring structure. (A)</p> Signup and view all the answers

What role does RNA primarily serve in the cell?

<p>RNA's primary function is the synthesis of proteins. (C)</p> Signup and view all the answers

What occurs during the formation of a nucleoside?

<p>A nitrogenous base is linked to a sugar without a phosphate. (D)</p> Signup and view all the answers

Which of the following statements regarding DNA strand direction is true?

<p>One strand runs 5' to 3', while the other runs 3' to 5'. (C)</p> Signup and view all the answers

What is the function of helicase during DNA replication?

<p>It unwinds the helix and separates the strands. (C)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing RNA primers during DNA replication?

<p>Primase (C)</p> Signup and view all the answers

What does DNA ligase do in the DNA replication process?

<p>It joins DNA segments on the lagging strand. (B)</p> Signup and view all the answers

According to Chargaff's rule, what is the relationship between adenine and thymine in DNA?

<p>The content of adenine equals the content of thymine. (C)</p> Signup and view all the answers

What is the primary role of DNA polymerase III during replication?

<p>It copies each strand of DNA. (A)</p> Signup and view all the answers

What process occurs when RNA is synthesized from a DNA template?

<p>Transcription (A)</p> Signup and view all the answers

What occurs during the replacement of RNA primers in DNA replication?

<p>DNA polymerase I replaces primers with DNA nucleotides. (B)</p> Signup and view all the answers

What does the enzyme helicase specifically break during DNA replication?

<p>Hydrogen bonds between DNA strands. (D)</p> Signup and view all the answers

What are Okazaki fragments formed from during DNA replication?

<p>Discontinuous synthesis on the lagging strand. (A)</p> Signup and view all the answers

What is the most stable form of DNA found under physiological conditions?

<p>B form (C)</p> Signup and view all the answers

What type of mutation does not affect the activity of the protein?

<p>Silence mutation (C)</p> Signup and view all the answers

Which form of DNA is characterized by a left-handed helix and a zigzag appearance?

<p>Z form (B)</p> Signup and view all the answers

What change occurs during a missense mutation?

<p>One amino acid is substituted for another. (A)</p> Signup and view all the answers

Which type of mutation could result in an incomplete protein due to a premature stop signal?

<p>Nonsense mutation (C)</p> Signup and view all the answers

Which characteristic distinguishes the A form of DNA?

<p>Right-handed double helix with wider turns (A)</p> Signup and view all the answers

What term describes a change in the DNA sequence that may lead to neutral effects on cell function?

<p>Polymorphism (D)</p> Signup and view all the answers

Which of the following is NOT a type of point mutation?

<p>Duplication mutation (D)</p> Signup and view all the answers

Which feature of lipids distinguishes them from other biomolecules?

<p>Soluble in non-polar organic solvents (B)</p> Signup and view all the answers

What type of mutation involves a change of single base pairs that creates a stop codon?

<p>Nonsense mutation (C)</p> Signup and view all the answers

How does the length of a fatty acid chain affect its melting temperature?

<p>Longer chain length increases melting temperature (A)</p> Signup and view all the answers

What type of fatty acid is characterized by one double bond?

<p>Monounsaturated fatty acid (A)</p> Signup and view all the answers

Which fatty acid has a higher melting temperature?

<p>Stearic acid (18:0) (B)</p> Signup and view all the answers

What effect does unsaturation have on the melting point of fatty acids?

<p>Decreases the melting point by inducing disorder (C)</p> Signup and view all the answers

Which of the following is considered a classification of fatty acids based on chain length?

<p>Short, medium, and long chain (A)</p> Signup and view all the answers

What role does saturation play in the physical properties of fatty acids?

<p>It promotes ordered formation and increases melting temperature (D)</p> Signup and view all the answers

What is the typical characteristic of a polyunsaturated fatty acid?

<p>Contains two or more double bonds (A)</p> Signup and view all the answers

What fatty acid is an example of a medium chain fatty acid?

<p>Lauric acid (12) (A)</p> Signup and view all the answers

Which statement best describes the relationship between chain length and Van der Waals forces in fatty acids?

<p>Long chain fatty acids have more Van der Waals forces (D)</p> Signup and view all the answers

What is a primary characteristic of short chain fatty acids?

<p>They are less than 6 carbon atoms in length (B)</p> Signup and view all the answers

What is the primary function of HMG-CoA reductase in biochemical reactions?

<p>Inhibit cholesterol synthesis (D)</p> Signup and view all the answers

Which enzyme is responsible for the conversion of lactate to pyruvate?

<p>Lactate dehydrogenase (B)</p> Signup and view all the answers

What type of reaction do oxidoreductases primarily facilitate?

<p>Oxidation and reduction reactions (B)</p> Signup and view all the answers

Which of the following enzymes catalyzes the removal of COO from pyruvate?

<p>Pyruvate decarboxylase (D)</p> Signup and view all the answers

Which of the following statements is true about transferases?

<p>They are involved in transferring functional or chemical groups. (D)</p> Signup and view all the answers

What is the function of messenger RNA (mRNA) in the cell?

<p>It carries information specifying the amino acid sequence to the ribosome. (D)</p> Signup and view all the answers

Which statement accurately describes the role of codons?

<p>They code for specific amino acids and dictate the order of amino acids in a protein. (C)</p> Signup and view all the answers

What occurs during the process of DNA replication?

<p>A single DNA molecule unwinds and daughter strands are synthesized. (C)</p> Signup and view all the answers

Which codons signify the end of a gene?

<p>UAA, UAG, and UGA (B)</p> Signup and view all the answers

At what stage does DNA replication occur within the cell cycle?

<p>During interphase (A)</p> Signup and view all the answers

What role do rRNA and tRNA play in translation?

<p>They help assemble amino acids into proteins. (B)</p> Signup and view all the answers

What is the significance of proofreading mechanisms during DNA replication?

<p>To ensure accurate base pairing and correct most replication errors. (B)</p> Signup and view all the answers

What distinguishes essential fatty acids (EFA) in animals?

<p>Animals require n-6 and n-3 fatty acids in their diets. (D)</p> Signup and view all the answers

Which type of fatty acids can animals not synthesize at the methyl end?

<p>Essential fatty acids. (A)</p> Signup and view all the answers

What is the main function of prostaglandins in the body?

<p>To mediate processes such as pain and inflammation. (A)</p> Signup and view all the answers

What is a characteristic difference between cis and trans fatty acids?

<p>Cis fatty acids are more commonly found in nature. (C)</p> Signup and view all the answers

Why do cats need long-chain fatty acids in their diet?

<p>They cannot carry out chain elongation and desaturation. (A)</p> Signup and view all the answers

How do animals utilize essential fatty acids from their diet?

<p>By incorporating them directly into cell membranes. (B)</p> Signup and view all the answers

What happens when an animal consumes aspirin during a fever?

<p>It inhibits enzyme activity related to prostaglandin production. (A)</p> Signup and view all the answers

What is a common characteristic of fatty acids with shorter carbon chains?

<p>They are more water-soluble than longer chains. (A)</p> Signup and view all the answers

Which statement accurately describes the role of n-6 and n-3 fatty acids in animals?

<p>They must be obtained through the diet. (D)</p> Signup and view all the answers

What is the primary role of eicosanoids in the body?

<p>Mediating physiological responses (D)</p> Signup and view all the answers

What type of triglyceride contains different fatty acids attached to glycerol?

<p>Mixed Triacylglycerol (D)</p> Signup and view all the answers

Which of the following accurately describes the function of triacylglycerol?

<p>Energy storage (A)</p> Signup and view all the answers

What is the typical energy yield of triglycerides compared to carbohydrates?

<p>9 cal/g (A)</p> Signup and view all the answers

What is a notable characteristic of eicosanoids in terms of their concentrations?

<p>Act at extremely low concentrations (C)</p> Signup and view all the answers

What is the primary component of simple glycerides?

<p>Fatty acids and glycerol (C)</p> Signup and view all the answers

Which fatty acid composition is typical for a diglyceride?

<p>Two fatty acids (B)</p> Signup and view all the answers

What allows triglycerides to be compact and lighter than other forms of energy storage?

<p>Absence of water (A)</p> Signup and view all the answers

What type of molecule serves as the parent structure for sphingolipids?

<p>Sphingosine (C)</p> Signup and view all the answers

What describes the relationship between DHA and neural development?

<p>DHA is necessary for proper neural function (C)</p> Signup and view all the answers

What is one of the main uses of waxes due to their low thermal conductivity?

<p>As insulators to slow down heat transfer (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of waxes?

<p>They are chemically unstable. (A)</p> Signup and view all the answers

What process occurs during the oxidation of triacylglycerols?

<p>Production of aldehydes or carboxylic acids (C)</p> Signup and view all the answers

What is a common application of lanolin?

<p>Protective treatment for baby skin (C)</p> Signup and view all the answers

What is the role of enzymes in biochemical reactions?

<p>They accelerate chemical reactions without being consumed. (D)</p> Signup and view all the answers

Which wax is specifically the secretion from honey bees?

<p>Beeswax (D)</p> Signup and view all the answers

What is a notable characteristic of cerumen?

<p>It is also called earwax. (D)</p> Signup and view all the answers

What type of molecules can result from the oxidation of alkenes?

<p>Aldehydes and/or carboxylic acids (D)</p> Signup and view all the answers

Which of the following waxes is frequently used for treating sore nipples in breastfeeding mothers?

<p>Lanolin (A)</p> Signup and view all the answers

What happens to a catalyst after it has facilitated a reaction?

<p>It is regenerated and can be reused. (A)</p> Signup and view all the answers

What is the most abundant type of RNA in protein synthesis?

<p>Ribosomal RNA (rRNA) (C)</p> Signup and view all the answers

Which statement accurately describes the role of transfer RNA (tRNA)?

<p>tRNA carries amino acids to the ribosome. (C)</p> Signup and view all the answers

Which part of protein synthesis involves reading genetic messages to create proteins?

<p>Translation (D)</p> Signup and view all the answers

What is the role of transcription in the central dogma of molecular biology?

<p>It copies DNA into RNA. (B)</p> Signup and view all the answers

Which of the following is NOT a step in protein synthesis?

<p>Replication (B)</p> Signup and view all the answers

What is the main chemical property of waxes that allows them to be used as insulators?

<p>Low thermal conductivity (C)</p> Signup and view all the answers

Which type of RNA is primarily responsible for carrying genetic codes from the nucleus to the ribosomes?

<p>Messenger RNA (mRNA) (B)</p> Signup and view all the answers

Which substance is classified as a wax secretion from honey bees?

<p>Bees wax (C)</p> Signup and view all the answers

What occurs as a result of the oxidation of triacylglycerols?

<p>Breakage of double bonds (B)</p> Signup and view all the answers

Which of the following is a use of lanolin?

<p>Protective baby skin treatment (B)</p> Signup and view all the answers

What is a characteristic of enzymes in biological systems?

<p>They accelerate chemical reactions (C)</p> Signup and view all the answers

What contributes to the hydrophilic nature of a fatty acid molecule?

<p>The terminal carboxyl group (A)</p> Signup and view all the answers

How does the degree of saturation affect the melting point of fatty acids?

<p>Unsaturated fatty acids have lower melting points than saturated ones. (D)</p> Signup and view all the answers

Which of the following statements about solubility is correct?

<p>Fatty acids with fewer than 10 carbon atoms are soluble in water. (C)</p> Signup and view all the answers

What is a common characteristic of most fatty acids?

<p>They have an even number of carbon atoms. (B)</p> Signup and view all the answers

How do unsaturated fatty acids compare in solubility to saturated fatty acids?

<p>Unsaturated fatty acids are more soluble. (B)</p> Signup and view all the answers

Which factor generally determines the melting temperature of fatty acids?

<p>The presence of double bonds (D)</p> Signup and view all the answers

What is the relationship between carbon atom count and water solubility in fatty acids?

<p>Greater than 10 carbon atoms lead to decreased solubility. (C)</p> Signup and view all the answers

Which characteristic makes unsaturated fatty acids more soluble than their saturated equivalents?

<p>The presence of double bonds (B)</p> Signup and view all the answers

What happens to the melting point of fatty acids when they contain double bonds?

<p>It decreases. (A)</p> Signup and view all the answers

What contributes to the lower solubility of long chain saturated fatty acids in water?

<p>Hydrophobic hydrocarbon chains (B)</p> Signup and view all the answers

What type of fatty acids are more soluble in water?

<p>Short chain fatty acids (D)</p> Signup and view all the answers

How does the presence of double bonds affect fatty acid solubility?

<p>Shortens the hydrocarbon chain (B)</p> Signup and view all the answers

What characteristic do fatty acids contain that contribute to their amphipathic nature?

<p>Both hydrophilic and hydrophobic groups (B)</p> Signup and view all the answers

Which fatty acids are categorized as bad cholesterol?

<p>Saturated fatty acids (C)</p> Signup and view all the answers

How does chain length affect the melting temperature of fatty acids?

<p>Longer chain lengths increase the melting temperature. (D)</p> Signup and view all the answers

What phase are saturated fatty acids typically in at room temperature?

<p>Solid (A)</p> Signup and view all the answers

What is true about unsaturated fatty acids regarding their melting temperature?

<p>Unsaturated fatty acids have lower melting temperatures due to disorder. (C)</p> Signup and view all the answers

Which of the following statements about the solubility of fatty acids is true?

<p>Higher concentration of double bonds increases solubility (C)</p> Signup and view all the answers

Which factor contributes to the ordered formation and increased melting temperature of fatty acids?

<p>Saturation allowing for more intermolecular attraction. (A)</p> Signup and view all the answers

What ultimately defines whether a fatty acid is soluble in water?

<p>The length of the hydrocarbon chain and double bond presence (C)</p> Signup and view all the answers

Which of the following fatty acids is an example of a polyunsaturated acid?

<p>Arachidonic acid (20:4) (A)</p> Signup and view all the answers

Which group in fatty acids contributes to their hydrophilicity?

<p>Carboxyl group (C)</p> Signup and view all the answers

What characteristic defines monounsaturated fatty acids?

<p>They have one double bond in their structure. (B)</p> Signup and view all the answers

What is a common characteristic of fatty acids with multiple double bonds?

<p>Lower melting points (C)</p> Signup and view all the answers

How are fatty acids classified based on their chain length?

<p>According to the number of carbon atoms in their chains. (B)</p> Signup and view all the answers

What is the melting temperature of stearic acid (18:0)?

<p>69.9 °C (C)</p> Signup and view all the answers

What effect does increased saturation have on fatty acids?

<p>Promotes more Van der Waals forces, increasing melting temperature. (B)</p> Signup and view all the answers

How does the degree of unsaturation relate to the physical state of fatty acids at room temperature?

<p>Unsaturated fatty acids tend to be liquid at room temperature. (A)</p> Signup and view all the answers

What distinguishes high-density lipoproteins (HDLs) from low-density lipoproteins (LDLs)?

<p>HDLs transport excess cholesterol from tissues to the liver, while LDLs carry cholesterol from the liver. (D)</p> Signup and view all the answers

What is a characteristic feature of a catalyst in a chemical reaction?

<p>It remains unchanged after the reaction occurs. (B)</p> Signup and view all the answers

What defines the metabolic activity of a holoenzyme?

<p>It contains a cofactor in addition to the apoenzyme. (B)</p> Signup and view all the answers

What happens to the melting temperature as the chain length of a fatty acid increases?

<p>It increases due to more Van der Waals bonds. (B)</p> Signup and view all the answers

Which type of fatty acid has one double bond and is typically liquid at room temperature?

<p>Monounsaturated fatty acid (A)</p> Signup and view all the answers

How does the degree of saturation affect the intermolecular attraction in fatty acids?

<p>More saturation increases ordered formation and attraction. (A)</p> Signup and view all the answers

Which fatty acid is classified as polyunsaturated?

<p>Arachidonic acid (C20:4) (D)</p> Signup and view all the answers

What is a characteristic of short-chain fatty acids?

<p>They typically have fewer than 6 carbon atoms. (A)</p> Signup and view all the answers

What is the primary component of a cerebroside?

<p>Ceramide and sugar (B)</p> Signup and view all the answers

How does unsaturation impact the melting point of fatty acids?

<p>It decreases the melting point due to disorder. (C)</p> Signup and view all the answers

What sugar component leads to the formation of a galactocerebroside?

<p>Galactose (D)</p> Signup and view all the answers

What type of fatty acid has the highest melting temperature among the example options?

<p>Stearic acid (C18:0) (A)</p> Signup and view all the answers

Which of the following lipids is primarily used in nerve tissue?

<p>Sphingomyelin (C)</p> Signup and view all the answers

What is a significant feature of cholesterol's structure?

<p>Four fused rings (D)</p> Signup and view all the answers

Which function is primarily associated with bile acids derived from cholesterol?

<p>Fat emulsification (B)</p> Signup and view all the answers

Which of the following components does NOT contribute to a sphingolipid's structure?

<p>Phosphoric acid (A)</p> Signup and view all the answers

What is a common role of cholesterol in the body?

<p>Steroid synthesis (A)</p> Signup and view all the answers

The polar sites of a phospholipid are described as being what?

<p>Hydrophilic (A)</p> Signup and view all the answers

What role do both hydrocarbon and polar parts of phospholipids play?

<p>Forming cell walls (D)</p> Signup and view all the answers

What is the primary function of triacylglycerols?

<p>Energy storage (B)</p> Signup and view all the answers

How many fatty acids are typically esterified to form a diglyceride?

<p>Two (D)</p> Signup and view all the answers

What distinguishes a mixed triacylglycerol from a simple triacylglycerol?

<p>It has different fatty acids attached to glycerol (A)</p> Signup and view all the answers

Which lipid is characterized as having a parent structure of sphingosine?

<p>Sphingolipids (C)</p> Signup and view all the answers

What essential fatty acid is noted for its role in neural and visual function development?

<p>Docosahexaenoic acid (DHA) (C)</p> Signup and view all the answers

What is a key characteristic of eicosanoids regarding their lifespan?

<p>They typically have a very short lifespan (A)</p> Signup and view all the answers

Which component is essential for the formation of ceramide?

<p>Fatty acid (A)</p> Signup and view all the answers

How are sphingomyelin and ceramide related?

<p>Sphingomyelin is ceramide plus phosphorylcholine. (A)</p> Signup and view all the answers

Which of the following accurately describes the composition of glycolipids?

<p>A fatty acid, sphingosine, and a carbohydrate (C)</p> Signup and view all the answers

What is a common function of lipids in the plasma membrane of neurons?

<p>Insulating nerve signals (A)</p> Signup and view all the answers

What constitutes the basic structure of all phosphoglycerides?

<p>Phosphatidic acid (B)</p> Signup and view all the answers

What type of lipids are primarily found in the myelin sheath of nerve tissues?

<p>Sphingomyelin (C)</p> Signup and view all the answers

Which property is necessary for lipids to function well in forming membranes?

<p>Possessing a polar and nonpolar portion (C)</p> Signup and view all the answers

What characteristic helps glycosphingolipids function as recognition sites on the cell surface?

<p>Their hydrophilic nature (C)</p> Signup and view all the answers

Flashcards

mRNA

Carries information for protein creation to the ribosome.

Translation

mRNA converts to protein sequence using rRNA and tRNA.

Codon

Three mRNA nucleotides that specify an amino acid.

Start codon

AUG (methionine), the initial codon in protein synthesis.

Signup and view all the flashcards

Stop codon

UAA, UAG, and UGA, signals the end of protein synthesis.

Signup and view all the flashcards

DNA Replication

Process of creating two identical DNA molecules from one.

Signup and view all the flashcards

DNA Replication Purpose

Ensures each daughter cell has a complete set of DNA.

Signup and view all the flashcards

Nonsense Mutation

A change in DNA sequence that creates a premature stop codon, resulting in a shortened and potentially non-functional protein.

Signup and view all the flashcards

Frameshift Mutation

An insertion or deletion of DNA bases that shifts the reading frame of a gene, causing a change in the amino acid sequence and often leading to a non-functional protein.

Signup and view all the flashcards

Deletion Mutation

A mutation where a segment of DNA is removed from a chromosome.

Signup and view all the flashcards

Duplication Mutation

A mutation where a segment of DNA is repeated on a chromosome.

Signup and view all the flashcards

Inversion Mutation

A mutation where a segment of DNA is flipped and re-inserted into a chromosome, reversing its order.

Signup and view all the flashcards

Translocation Mutation

A mutation where a segment of DNA moves from one chromosome to a non-homologous chromosome. The most common type is a reciprocal translocation where chromosomes exchange segments.

Signup and view all the flashcards

Triacylglycerols

Energy storage lipids composed of three fatty acids linked to glycerol.

Signup and view all the flashcards

Phospholipids

Membrane lipids with a phosphate group attached to glycerol. Form the structural basis of cell membranes.

Signup and view all the flashcards

PCR

A technique that amplifies a specific DNA region in vitro by denaturing, annealing primers, and extending new strands. It is used for DNA analysis and research.

Signup and view all the flashcards

Eicosanoids

Local hormones that mediate various physiological responses, including inflammation, anaphylaxis, and smooth muscle contraction.

Signup and view all the flashcards

Arachidonic Acid

A 20-carbon fatty acid that serves as a precursor for eicosanoid synthesis.

Signup and view all the flashcards

Eicosanoids' Effect

They have profound physiological effects at extremely low concentrations, meaning a small amount can have a big impact.

Signup and view all the flashcards

Eicosanoids' Lifetime

Eicosanoids typically have a very short lifespan, meaning they act locally and quickly.

Signup and view all the flashcards

Simple Glycerides

Esters of glycerol and one or more fatty acids, primarily serving as energy storage (fats).

Signup and view all the flashcards

Monoglyceride

A glyceride formed by esterification of one fatty acid to glycerol.

Signup and view all the flashcards

Diglyceride

A glyceride formed by esterification of two fatty acids to glycerol.

Signup and view all the flashcards

Triacylglycerol Energy

It yields 9 calories per gram, greater than that of carbohydrates or proteins, making it an efficient energy source.

Signup and view all the flashcards

Sphingolipids

Lipids with a sphingosine backbone, serving various functions in the body.

Signup and view all the flashcards

Bile Salts: Taurocholate

A primary bile salt with taurine attached at carbon 17, aiding in fat digestion.

Signup and view all the flashcards

Bile Salts: Glycocholate

A primary bile salt with glycine attached at carbon 17, also helping break down fats.

Signup and view all the flashcards

Saturated Fats

Fats with single bonds between all carbon atoms, generally solid at room temperature.

Signup and view all the flashcards

Monounsaturated Fats

Fats with one double bond between carbon atoms, usually liquid at room temperature.

Signup and view all the flashcards

Trans-Monounsaturated Fats

Monounsaturated fats with a specific spatial arrangement, considered unhealthy, often found in processed foods.

Signup and view all the flashcards

Polyunsaturated Fats

Fats with multiple double bonds between carbon atoms, can be healthy or unhealthy depending on type.

Signup and view all the flashcards

Omega-3 and Omega-6 Fatty Acids

Important polyunsaturated fats, found in fish and plant oils, known for their health benefits.

Signup and view all the flashcards

Fats vs. Oils: Difference

Fats are mostly saturated, solid at room temperature, from animal sources; Oils are mostly unsaturated, liquid at room temperature, from plants and fish.

Signup and view all the flashcards

Triacylglycerol Hydrolysis

The breakdown of triacylglycerols (fats) into fatty acids and glycerol, the reverse of esterification.

Signup and view all the flashcards

Waxes' Unique Property

Waxes are hydrophobic, meaning they repel water and don't dissolve in it, making them suitable for protective coatings.

Signup and view all the flashcards

What is a holoenzyme?

A complete and active enzyme consisting of an apoenzyme (protein portion) and a cofactor (non-protein portion).

Signup and view all the flashcards

What are cofactors?

Non-protein molecules that assist enzymes in their catalytic activity. They can be coenzymes (small organic molecules), prosthetic groups (organic molecules tightly bound to the enzyme), or metal ions.

Signup and view all the flashcards

What is a catalyst?

A substance that speeds up a chemical reaction without being consumed in the process.

Signup and view all the flashcards

What do LDLs and HDLs do?

Low-density lipoproteins (LDLs) transport cholesterol from the liver to tissues, while high-density lipoproteins (HDLs) bring excess cholesterol back to the liver.

Signup and view all the flashcards

What are statins?

A class of drugs that lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol biosynthesis.

Signup and view all the flashcards

Complementary base pairing

The specific pairing of nitrogenous bases in DNA: Adenine (A) always pairs with Thymine (T), and Guanine (G) always pairs with Cytosine (C). This pairing ensures accurate replication.

Signup and view all the flashcards

Leading strand

The strand of DNA that is synthesized continuously during replication, following the direction of the replication fork.

Signup and view all the flashcards

Lagging strand

The strand of DNA that is synthesized discontinuously during replication, in short fragments called Okazaki fragments, moving away from the replication fork.

Signup and view all the flashcards

Okazaki fragments

Short DNA fragments synthesized on the lagging strand during replication, which are later joined together by DNA ligase.

Signup and view all the flashcards

DNA Helicase

The enzyme responsible for unwinding the DNA double helix during replication, breaking the hydrogen bonds between the base pairs.

Signup and view all the flashcards

DNA Polymerase

The enzyme responsible for synthesizing new DNA strands during replication, adding nucleotides one by one to the growing strand.

Signup and view all the flashcards

Point Mutation

A change in a single DNA base pair, potentially altering the protein sequence.

Signup and view all the flashcards

Polymerase Chain Reaction (PCR)

A technique to amplify specific DNA regions in vitro by repeatedly denaturing, annealing primers, and extending new strands.

Signup and view all the flashcards

Lipid Classification

Lipids are classified mainly by their solubility in different solvents, not by functional groups.

Signup and view all the flashcards

Enzyme Specificity

Enzymes are very picky about what they work on. They have a specific shape that only fits with a particular molecule (substrate).

Signup and view all the flashcards

Active Site

The special region on an enzyme where the substrate binds. It's like a pocket that's tailored for a specific molecule.

Signup and view all the flashcards

Cofactor

A small molecule that helps an enzyme do its job. It's like an assistant for the enzyme.

Signup and view all the flashcards

Apoenzyme

The protein part of an enzyme, the main part that does the work. But it needs a cofactor to complete its job.

Signup and view all the flashcards

Enzyme's Role in Reaction Rate

Enzymes speed up chemical reactions by lowering the activation energy. It's like making it easier for the reaction to happen.

Signup and view all the flashcards

What are antioxidants?

Substances that protect against damage caused by free radicals. They're like bodyguards for your cells.

Signup and view all the flashcards

How do antioxidants work?

Antioxidants donate an electron to reactive molecules called free radicals, neutralizing their harmful effects.

Signup and view all the flashcards

Examples of Antioxidants

Vitamin C and Vitamin E are common and good antioxidants.

Signup and view all the flashcards

Hydrogenation of Unsaturated Fats

Adding hydrogen to unsaturated fats to make them more solid. This changes the structure of the fat by converting double bonds to single bonds.

Signup and view all the flashcards

Why is Hydrogenation Used?

Hydrogenation is used to make fats more solid at room temperature. It's used in making margarine, shortening, and fried foods.

Signup and view all the flashcards

Amino Acid Structure

Amino acids are the building blocks of proteins, composed of a central carbon atom bonded to an amino group (NH2), a carboxyl group (COOH), a hydrogen atom, and a side chain (R). The side chain determines the amino acid's specific properties.

Signup and view all the flashcards

Zwitterion

Under normal cellular conditions, amino acids exist as zwitterions, which are dipolar ions with both a positive and negative charge. The amino group is protonated (NH3+) and the carboxyl group is deprotonated (COO-), resulting in a neutral overall charge.

Signup and view all the flashcards

Isoelectric Point

The isoelectric point (pI) is the pH at which an amino acid solution has no net charge. At this pH, the amino acid exists primarily as its zwitterionic form, with an equal number of positive and negative charges.

Signup and view all the flashcards

Enantiomers

Enantiomers are mirror image pairs of amino acids, designated as L (levo) and D (dextro). They have identical chemical formulas but differ in their spatial arrangement, making them non-superimposable mirror images.

Signup and view all the flashcards

Protein Stereochemistry

Proteins are primarily assembled from L-amino acids, while carbohydrates are typically D-isomers. This difference in stereochemistry contributes to the diversity and functionality of biological molecules.

Signup and view all the flashcards

HMG-CoA reductase

An enzyme responsible for the synthesis of cholesterol in the body. It is the target of statin drugs which lower cholesterol levels.

Signup and view all the flashcards

Oxidation

The loss of electrons by a molecule during a chemical reaction. It often involves the gain of oxygen or loss of hydrogen.

Signup and view all the flashcards

Reduction

The gain of electrons by a molecule during a chemical reaction. It often involves the loss of oxygen or gain of hydrogen.

Signup and view all the flashcards

Dehydrogenase Enzyme

A type of enzyme that catalyzes the removal of hydrogen atoms (oxidation) from a molecule often transferring them to a coenzyme like NAD+.

Signup and view all the flashcards

Transferases

Enzymes that transfer functional groups from one molecule to another. They are involved in many essential metabolic processes.

Signup and view all the flashcards

Isomerases

Enzymes that rearrange atoms within a molecule, changing its structure and creating an isomer. They don't break or form bonds.

Signup and view all the flashcards

Fatty Acids

Building blocks of lipids, made of hydrocarbon chains with a carboxyl group. They are a major source of stored energy in the body.

Signup and view all the flashcards

Saturated Fatty Acid

A fatty acid with only single bonds between carbon atoms. They are generally solid at room temperature and found in animal fats.

Signup and view all the flashcards

Unsaturated Fatty Acid

A fatty acid with at least one double bond between carbon atoms. They are generally liquid at room temperature and found in plant oils.

Signup and view all the flashcards

Solubility & Fatty Acids

Fatty acids are generally insoluble in water due to their long hydrocarbon chains. However, their carboxyl group makes them slightly hydrophilic, allowing for some interaction with water.

Signup and view all the flashcards

Melting Point & Fatty Acids

The melting point of a fatty acid increases with chain length and decreases with the presence of double bonds. Shorter, saturated chains have higher melting points, making them solid at room temperature.

Signup and view all the flashcards

Cis vs. Trans Fatty Acids

Cis fatty acids have their hydrogen atoms on the same side of the double bond, resulting in a bent shape. Trans fatty acids have hydrogens on opposite sides of the double bond, making the chain straighter.

Signup and view all the flashcards

Glycolipids

Lipids that contain a fatty acid, sphingosine, and a carbohydrate. They are important for cell recognition and signaling.

Signup and view all the flashcards

Ceramide

A lipid molecule formed when sphingosine combines with a fatty acid. It serves as a building block for other complex lipids like sphingomyelin.

Signup and view all the flashcards

Phosphatidic Acid

The basic structure of all phosphoglycerides, consisting of glycerol, two fatty acids, and a phosphate group.

Signup and view all the flashcards

Sphingomyelin

A type of sphingolipid found in nerve tissue, particularly in the myelin sheath that insulates nerve fibers.

Signup and view all the flashcards

Lipid Bilayer

The structure of cell membranes, composed of two layers of phospholipids with their hydrophobic tails facing inward and hydrophilic heads facing outward.

Signup and view all the flashcards

Structural Role of Phospholipids

Phospholipids are the main components of cell membranes, forming a lipid bilayer that controls the movement of substances in and out of cells.

Signup and view all the flashcards

Why are phospholipids important for membranes?

Phospholipids have both a polar (hydrophilic) head and a nonpolar (hydrophobic) tail, which allows them to form a stable bilayer structure in aqueous environments, essential for cell membranes.

Signup and view all the flashcards

What are the key components of a phospholipid?

A phospholipid consists of a glycerol backbone, two fatty acid chains, and a phosphate group with a polar head group.

Signup and view all the flashcards

Cerebroside

A type of sphingolipid composed of a ceramide molecule (sphingosine + fatty acid) linked to a single sugar molecule.

Signup and view all the flashcards

Glucocerebroside

A cerebroside with glucose as the attached sugar.

Signup and view all the flashcards

Galactocerebroside

A cerebroside with galactose as the attached sugar.

Signup and view all the flashcards

Sulfatide

A cerebroside with a sulfated sugar attached.

Signup and view all the flashcards

Ganglioside

A complex sphingolipid with a ceramide linked to an oligosaccharide containing sialic acid (NANA).

Signup and view all the flashcards

Cholesterol

A steroid with four fused rings, important for cell membrane structure and hormone synthesis.

Signup and view all the flashcards

Bile Acids

Steroid derivatives of cholesterol, produced in the liver and stored in the gallbladder, that aid in fat digestion.

Signup and view all the flashcards

Hydrophilic

Water-loving; refers to molecules that readily interact with water.

Signup and view all the flashcards

Hydrophobic

Water-fearing; refers to molecules that repel water and do not readily interact with it.

Signup and view all the flashcards

Lyases

Enzymes that cleave C-C, C-O or C-N bonds through mechanisms other than hydrolysis or oxidation.

Signup and view all the flashcards

Dehydratases

Lyases that remove water (H2O) from a substrate.

Signup and view all the flashcards

Decarboxylases

Lyases that remove carbon dioxide (CO2) from a substrate.

Signup and view all the flashcards

Deaminases

Lyases that remove ammonia (NH3) from a substrate.

Signup and view all the flashcards

Hydratase

Lyases that add water (H2O) to a substrate.

Signup and view all the flashcards

Bile Salts

Substances produced by the liver that help digest fats by breaking them down into smaller droplets.

Signup and view all the flashcards

Taurocholate

A type of bile salt that has taurine attached to it.

Signup and view all the flashcards

Glycocholate

A type of bile salt that has glycine attached to it.

Signup and view all the flashcards

Fats vs. Oils

Fats are mainly saturated, solid at room temperature, and typically come from animal sources. Oils are mainly unsaturated, liquid at room temperature, and come from plants or fish.

Signup and view all the flashcards

Amphipathic

A molecule with both hydrophilic (water-loving) and hydrophobic (water-fearing) regions.

Signup and view all the flashcards

Double Bonds & Solubility

Increasing the number of double bonds in a fatty acid increases its solubility in water.

Signup and view all the flashcards

Cis Fatty Acids

Fatty acids with hydrogen atoms on the same side of the double bond, creating a bent shape.

Signup and view all the flashcards

Trans Fatty Acids

Fatty acids with hydrogen atoms on opposite sides of the double bond, creating a straighter shape.

Signup and view all the flashcards

Why are trans fats unhealthy?

Trans fats are unhealthy because they can raise LDL ('bad') cholesterol levels and lower HDL ('good') cholesterol levels, increasing the risk of heart disease.

Signup and view all the flashcards

Butyric Acid

A short-chain fatty acid found in coconut oil. It is not soluble in water.

Signup and view all the flashcards

Essential Fatty Acids (EFAs)

Fatty acids that animals cannot synthesize and must obtain from their diet. Examples include linoleic acid (18:2(n-6)) and linolenic acid (18:3(n-3)).

Signup and view all the flashcards

Prostaglandins

Hormone-like substances derived from 20-carbon fatty acids that play important roles in inflammation, pain, fever, and blood clotting.

Signup and view all the flashcards

Why do animals need EFAs?

Animals cannot insert double bonds at the methyl end of fatty acids, so they need EFAs in their diet to obtain these molecules.

Signup and view all the flashcards

Chain Elongation and Desaturation

Processes that allow animals to lengthen and add double bonds to existing fatty acids, but they cannot modify the end of the fatty acid chain.

Signup and view all the flashcards

Aspirin and Prostaglandins

Aspirin reduces fever by inhibiting the enzyme that makes prostaglandins. Prostaglandins contribute to pain, inflammation, and fever.

Signup and view all the flashcards

How do melting points differ?

Shorter fatty acids have lower melting points, and more double bonds lower melting points.

Signup and view all the flashcards

Water Solubility & Fatty Acids

Short-chain fatty acids are more soluble in water than long-chain fatty acids because the carboxyl group is hydrophilic.

Signup and view all the flashcards

Triacylglycerols (Triglycerides)

The main way our body stores energy, consisting of three fatty acids attached to a glycerol molecule.

Signup and view all the flashcards

Mixed Triacylglycerol

A triacylglycerol where the fatty acids attached to glycerol are all different.

Signup and view all the flashcards

Bile Salts Purpose

Bile salts are produced by the liver and aid in fat digestion by breaking large fat molecules into smaller droplets, making them easier to digest and absorb.

Signup and view all the flashcards

Amino Acid

The building blocks of proteins, composed of a central carbon bonded to an amino group, a carboxyl group, a hydrogen atom, and a side chain (R).

Signup and view all the flashcards

Isoelectric Point (pI)

The pH at which an amino acid solution has no net charge.

Signup and view all the flashcards

Messenger RNA (mRNA)

A type of RNA that carries the genetic code from DNA to the ribosome, where proteins are synthesized. It's the only type of RNA that is directly translated into protein.

Signup and view all the flashcards

What is DNA replication?

The process of creating two identical DNA molecules from one original DNA molecule. It's essential for cell division, ensuring each daughter cell receives a complete copy of the genetic information.

Signup and view all the flashcards

DNA Repair Mechanisms

Cellular mechanisms that continuously monitor and fix errors that occur during DNA replication, preventing mutations and ensuring accurate genetic information.

Signup and view all the flashcards

What makes fatty acids amphipathic?

Fatty acids have a hydrophilic carboxyl group (COOH) at one end and a hydrophobic hydrocarbon chain at the other end. This dual nature makes them amphipathic.

Signup and view all the flashcards

Solubility of Fatty Acids in Water

Short-chain fatty acids (C2-C10) are somewhat soluble in water due to their polar carboxyl group. However, as the hydrocarbon chain lengthens and the number of double bonds decreases, solubility in water decreases.

Signup and view all the flashcards

Saturated vs. Unsaturated Fats

Saturated fats have only single bonds between carbon atoms, making them solid at room temperature. Unsaturated fats have at least one double bond, which makes them liquid at room temperature.

Signup and view all the flashcards

Cholesterol Structure

Cholesterol is a steroid with four fused rings. It's a key component of cell membranes and a precursor for various hormones.

Signup and view all the flashcards

What are bile salts?

They are steroid derivatives produced by the liver that aid in fat digestion. They help break down large fat droplets into smaller ones for easier absorption.

Signup and view all the flashcards

What are taurocholate and glycocholate?

They are primary bile salts, with taurine and glycine attached, respectively. Both help break down fats in the digestive system.

Signup and view all the flashcards

Importance of Lipids

Lipids are a diverse group of molecules important for energy storage, cell membrane structure, insulation, and hormone synthesis.

Signup and view all the flashcards

Why eat before aspirin?

Aspirin inhibits prostaglandins, which protect the stomach lining. Eating food acts as a buffer against aspirin's irritation.

Signup and view all the flashcards

Thromboxanes

A type of eicosanoid derived from arachidonic acid that promotes blood clotting and reduces blood flow to the clot.

Signup and view all the flashcards

Why aspirin is contraindicated in dengue fever?

Aspirin inhibits platelet aggregation, worsening dengue fever's bleeding due to its anti-platelet and anticoagulant effect.

Signup and view all the flashcards

Trans fatty acids: bad?

Trans fats are straight, easily pack together, increasing risk of heart disease by raising LDL cholesterol.

Signup and view all the flashcards

Leukotrienes

Eicosanoids that mediate allergic and inflammatory responses.

Signup and view all the flashcards

LTB4

Leukotriene that increases vascular permeability, leukocyte aggregation, and inflammation.

Signup and view all the flashcards

LTC4 and LTD4

Leukotrienes that cause bronchoconstriction, vascular permeability, and hypersensitivity.

Signup and view all the flashcards

What makes a fatty acid more soluble in water?

Shorter chains and more double bonds increase solubility in water. This is because the shorter chain reduces the hydrophobic part and the double bonds create kinks that disrupt the tight packing of the hydrophobic tails, allowing for greater interaction with water.

Signup and view all the flashcards

Trans-Monounsaturated Fatty Acids

Monounsaturated fatty acids with hydrogen atoms on opposite sides of the double bond. They have a straight shape and are considered unhealthy.

Signup and view all the flashcards

Lock and Key Model

Explains how a substrate fits perfectly into an enzyme's active site, like a key into a lock. It assumes the enzyme is rigid.

Signup and view all the flashcards

Induced Fit Model

Explains how an enzyme's shape changes slightly to fit around a substrate. It allows for more flexibility in the interaction.

Signup and view all the flashcards

Competitive Inhibition

Inhibition where a molecule (inhibitor) competes with the substrate for the enzyme's active site.

Signup and view all the flashcards

Non-Competitive Inhibition

Inhibition where a molecule binds to the enzyme at a site other than the active site, changing its shape and preventing substrate binding.

Signup and view all the flashcards

DNA vs. RNA

DNA is the genetic blueprint found in the nucleus, storing and transferring genetic information. RNA is involved in protein synthesis and occurs throughout the cell.

Signup and view all the flashcards

Purine vs. Pyrimidine

Purines (Adenine and Guanine) have a double-ring structure, while pyrimidines (Cytosine and Thymine) have a single ring structure.

Signup and view all the flashcards

What is a nucleotide?

A nucleotide is the basic building block of nucleic acids (DNA and RNA), composed of a nitrogenous base, a sugar, and a phosphate group.

Signup and view all the flashcards

Ribose vs. Deoxyribose

Ribose is the sugar found in RNA, while deoxyribose is the sugar found in DNA. Deoxyribose has one less oxygen atom than ribose.

Signup and view all the flashcards

Base Pairing

In DNA, Adenine (A) always pairs with Thymine (T), and Guanine (G) always pairs with Cytosine (C).

Signup and view all the flashcards

Anti-parallel Strands

DNA strands run in opposite directions: one strand runs 5’ to 3’, the other runs 3’ to 5’.

Signup and view all the flashcards

Side Chain (R)

The unique chemical group attached to the central carbon of an amino acid, determining its properties (hydrophobic, hydrophilic, charged).

Signup and view all the flashcards

Peptide Bond

A covalent bond formed between the carboxyl group of one amino acid and the amino group of another, linking amino acids in a chain.

Signup and view all the flashcards

Protein Function

Proteins perform various roles in the body, e.g., structural support, catalysis, transport, cell signalling, defense.

Signup and view all the flashcards

Inhibitors

Molecules that bind to an enzyme and reduce its activity, slowing down the reaction rate.

Signup and view all the flashcards

Activators

Molecules that bind to an enzyme and increase its activity, speeding up the reaction rate.

Signup and view all the flashcards

Protein Misfolding

A protein adopts an abnormal 3D structure, deviating from its native conformation, leading to compromised functionality.

Signup and view all the flashcards

Chaperones

Proteins that assist in proper protein folding, preventing misfolding and aiding in regaining the native conformation.

Signup and view all the flashcards

Quality Control Mechanisms

Cellular systems that detect and dispose of misfolded proteins, preventing accumulation and potential cell damage.

Signup and view all the flashcards

Amyloid-Beta

A protein involved in Alzheimer's disease, accumulating as plaques due to misfolding and disrupting brain function.

Signup and view all the flashcards

Peptide vs. Protein

Peptides are short chains of amino acids (less than 50), while proteins are longer chains (more than 50).

Signup and view all the flashcards

Central Dogma

The fundamental principles of molecular biology that describe the flow of genetic information from DNA to RNA to protein.

Signup and view all the flashcards

Replication

The process of making an identical copy of DNA, ensuring the genetic information is passed on to new cells.

Signup and view all the flashcards

Transcription

The process of using DNA as a template to create a messenger RNA (mRNA) molecule, which carries the genetic code to the ribosomes.

Signup and view all the flashcards

Ribosomal RNA (rRNA)

A type of RNA that forms part of the ribosome, the cellular machinery responsible for protein synthesis.

Signup and view all the flashcards

Transfer RNA (tRNA)

A type of RNA that carries amino acids to the ribosome, where they are added to the growing protein chain.

Signup and view all the flashcards

What is the role of rRNA in protein synthesis?

Ribosomal RNA (rRNA) forms part of the ribosome, the cellular machinery responsible for protein synthesis. rRNA provides structural support and enzymatic activity for the ribosome to read mRNA and assemble amino acids into a protein chain.

Signup and view all the flashcards

Amphipathic molecule

A molecule with both hydrophilic (water-loving) and hydrophobic (water-fearing) regions.

Signup and view all the flashcards

What makes fatty acids soluble in water?

The carboxyl group on a fatty acid is hydrophilic (polar), making it slightly soluble in water. The length of the hydrocarbon chain and the number of double bonds also affect solubility.

Signup and view all the flashcards

How do double bonds impact solubility?

Increasing the number of double bonds in a fatty acid makes it more soluble in water because it shortens the hydrocarbon chain, making it less hydrophobic.

Signup and view all the flashcards

Phospholipids: Structure

They have a 'head' and a 'tail'. The head is polar (hydrophilic) and the tail is nonpolar (hydrophobic). This duality is crucial for cell membrane formation.

Signup and view all the flashcards

Phospholipids: Importance in Membranes

They form the basis of cell membranes, creating a barrier that regulates what enters and exits the cell.

Signup and view all the flashcards

Phospholipids: Key Components

A glycerol backbone, two fatty acid chains, and a phosphate group with a polar head group.

Signup and view all the flashcards

Ceramides: Building Blocks

They are the building blocks for more complex sphingolipids, which have diverse cellular functions.

Signup and view all the flashcards

What is a cerebroside?

A type of sphingolipid with a ceramide molecule (sphingosine + fatty acid) linked to a single sugar molecule.

Signup and view all the flashcards

Catalyst

A substance that speeds up a reaction without being consumed in the process. It lowers the activation energy needed to start the reaction.

Signup and view all the flashcards

LDL & HDL

Low-density lipoproteins (LDLs) carry cholesterol from the liver to tissues. High-density lipoproteins (HDLs) bring excess cholesterol back to the liver.

Signup and view all the flashcards

What are the two most important bile salts?

The two most important bile salts are taurocholate and glycocholate.

Signup and view all the flashcards

What are waxes' unique properties?

Waxes are solid at room temperature, have a low melting point, act as insulators, lubricate, and are chemically stable, making them useful for diverse applications.

Signup and view all the flashcards

What is saponification?

Saponification is the hydrolysis of fats in a basic solution, producing soap (fatty acid salts) and glycerol.

Signup and view all the flashcards

What are enzymes?

Enzymes are specialized protein catalysts that accelerate biological reactions without being consumed. They make reactions happen much faster.

Signup and view all the flashcards

What is oxidation?

Oxidation is the loss of electrons by a molecule, often involving the gain of oxygen or loss of hydrogen.

Signup and view all the flashcards

What are triacylglycerols?

Triacylglycerols are fats made of three fatty acids linked to a glycerol molecule. They are our body's main way to store energy.

Signup and view all the flashcards

What do bile salts do?

Bile salts are produced by the liver and help digest fats by breaking them down into smaller droplets.

Signup and view all the flashcards

What is the role of phospholipids in membranes?

Phospholipids form the structural basis of cell membranes, creating a lipid bilayer that controls what enters and exits cells.

Signup and view all the flashcards

Why are saturated fats solid at room temperature?

Saturated fats have only single bonds between carbon atoms, making them straight and able to pack tightly together, leading to a solid state.

Signup and view all the flashcards

What are the differences between cis and trans fatty acids?

Cis fatty acids have hydrogens on the same side of the double bond, bending the chain, while trans fatty acids have hydrogens on opposite sides, keeping the chain straight.

Signup and view all the flashcards

Types of Lipids

Lipids are classified by their solubility. They are insoluble or sparingly soluble in water but soluble in non-polar organic solvents.

Signup and view all the flashcards

Impact of Double Bonds

Double bonds in fatty acids decrease the melting point and increase solubility in water. This is because double bonds introduce kinks in the molecule.

Signup and view all the flashcards

How do double bonds affect fatty acid structure?

Double bonds create bends or kinks in the fatty acid chain, altering its shape and affecting its interactions with other molecules.

Signup and view all the flashcards

Short Chain Fatty Acids

Fatty acids with a hydrocarbon chain of less than 10 carbons. They are sparingly soluble in water due to the polar carboxyl group.

Signup and view all the flashcards

Solubility & Double Bonds

Increasing the number of double bonds in a fatty acid makes it more soluble in water. This is because double bonds create kinks in the chain, making it less hydrophobic.

Signup and view all the flashcards

Why Hydrolysis of Fats?

Hydrolysis breaks down fats (triacylglycerols) into fatty acids and glycerol. This allows the body to access the stored energy in fats.

Signup and view all the flashcards

Purines

Double-ringed nitrogenous bases found in DNA and RNA. Examples include Adenine (A) and Guanine (G).

Signup and view all the flashcards

Pyrimidines

Single-ringed nitrogenous bases found in DNA and RNA. Examples include Cytosine (C) and Thymine (T) (in DNA) or Uracil (U) (in RNA).

Signup and view all the flashcards

Nucleoside

A molecule composed of a nitrogenous base attached to a sugar (ribose or deoxyribose) without phosphate.

Signup and view all the flashcards

Nucleotide

A building block of nucleic acids (DNA & RNA) consisting of a nitrogenous base, a sugar (ribose or deoxyribose), and a phosphate group.

Signup and view all the flashcards

Chargaff's Rule

The content of Adenine (A) in DNA is equal to the content of Thymine (T), and the content of Guanine (G) is equal to the content of Cytosine (C).

Signup and view all the flashcards

Silent Mutation

A point mutation that doesn't change the amino acid sequence of a protein.

Signup and view all the flashcards

Lipid

A biological molecule that is insoluble in water but soluble in non-polar solvents (like fats and oils)

Signup and view all the flashcards

What are essential fatty acids?

Essential fatty acids (EFAs) are fatty acids that the body cannot synthesize and must be obtained from the diet. They are crucial for various physiological processes, including cell growth, inflammation, and immune function.

Signup and view all the flashcards

What are the two main types of essential fatty acids?

The two main types of essential fatty acids are omega-3 (n-3) and omega-6 (n-6) fatty acids. They have different chemical structures and contribute to different physiological effects.

Signup and view all the flashcards

What is a prostaglandin?

A prostaglandin is a type of lipid molecule derived from a 20-carbon fatty acid, containing a cyclopentane ring. It acts as a local hormone, involved in a wide range of biological functions, including inflammation, pain, and fever.

Signup and view all the flashcards

What is the difference between cis and trans fatty acids?

Cis fatty acids have their hydrogen atoms on the same side of the double bond, resulting in a bent shape. Trans fatty acids have their hydrogen atoms on opposite sides of the double bond, making the chain straighter.

Signup and view all the flashcards

What is the effect of a shorter carbon chain on a fatty acid's melting point?

Shorter carbon chains in fatty acids generally have lower melting points, meaning they are more likely to be liquid at room temperature.

Signup and view all the flashcards

Fatty Acid Chain Length & Melting Point

Longer fatty acid chains have higher melting points, meaning they are more likely to be solid at room temperature. This is because longer chains have more surface area for Van der Waals forces to act upon, leading to stronger intermolecular attractions.

Signup and view all the flashcards

Saturation & Melting Point

Saturated fatty acids (no double bonds) have higher melting points than unsaturated fatty acids (have double bonds). This is because saturated chains are more linear and can pack together tightly, increasing Van der Waals forces.

Signup and view all the flashcards

What makes fats solid at room temperature?

Fats are typically solid at room temperature because they are mostly composed of saturated fatty acids. These saturated chains can pack closely together due to their linear structure, leading to strong intermolecular attractions and a higher melting point.

Signup and view all the flashcards

What makes oils liquid at room temperature?

Oils are liquid at room temperature because they are mostly composed of unsaturated fatty acids. The double bonds in unsaturated chains create kinks, preventing them from packing as tightly as saturated chains, resulting in weaker intermolecular forces and a lower melting point.

Signup and view all the flashcards

What does 'good cholesterol' do in the body?

High-density lipoprotein (HDL) is commonly called 'good cholesterol' because it picks up excess cholesterol from the bloodstream and delivers it back to the liver for processing and elimination, reducing the risk of heart disease.

Signup and view all the flashcards

Why are Statins Used?

Statins are a class of drugs used to lower cholesterol levels in the body. They work by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol production.

Signup and view all the flashcards

What is the purpose of DNA replication?

To ensure that each daughter cell receives a complete set of genetic information, allowing for cell division and growth.

Signup and view all the flashcards

Why are n-6 and n-3 EFAs essential?

Animals lack the enzymes to insert double bonds at the methyl (n-6) and n-3 ends of fatty acids. These EFAs are needed for various biochemical pathways and cannot be synthesized in the body.

Signup and view all the flashcards

Simple Triacylglycerol

A type of triacylglycerol where all the fatty acids attached to glycerol are the same.

Signup and view all the flashcards

What is the difference between mixed and simple triacylglycerols?

Mixed triacylglycerols have different fatty acids attached to glycerol, while simple triacylglycerols have all the same type of fatty acids attached.

Signup and view all the flashcards

How do eicosanoids differ from other hormones?

Eicosanoids act as local hormones, meaning they affect cells in the immediate vicinity, while other hormones travel through the bloodstream to distant target cells.

Signup and view all the flashcards

Why are triacylglycerols a good form of energy storage?

Triacylglycerols are compact, energy-dense, and hydrophobic, allowing for efficient storage and release of energy.

Signup and view all the flashcards

What are waxes?

Waxes are esters formed from long-chain fatty acids and long-chain alcohols. They are solid at room temperature, have low melting points, and provide insulation and lubrication.

Signup and view all the flashcards

What do enzymes do?

Enzymes speed up chemical reactions without being consumed in the process. They lower the activation energy needed for the reaction to occur.

Signup and view all the flashcards

What is triacylglycerol oxidation?

The double bonds in triacylglycerols can be oxidized by oxygen in the air.

Signup and view all the flashcards

What happens when triacylglycerols are oxidized?

Oxidation of triacylglycerols breaks the double bonds, producing aldehydes and carboxylic acids.

Signup and view all the flashcards

What are simple glycerides?

Simple glycerides are esters of glycerol and one or more fatty acids. They are primarily used for energy storage.

Signup and view all the flashcards

What are phospholipids?

Phospholipids are lipids with a phosphate group attached to glycerol. They form the structural basis of cell membranes.

Signup and view all the flashcards

What is the role of bile salts?

Bile salts, produced by the liver, help digest fats by breaking them down into smaller droplets.

Signup and view all the flashcards

Statins

Drugs that lower cholesterol levels by blocking the activity of HMG-CoA reductase, preventing the formation of cholesterol.

Signup and view all the flashcards

What are the three types of RNA in protein synthesis?

The three types of RNA involved in protein synthesis are ribosomal RNA (rRNA), messenger RNA (mRNA), and transfer RNA (tRNA).

Signup and view all the flashcards

Fatty Acid Solubility

The solubility of fatty acids in water decreases as the length of the hydrocarbon chain increases and the number of double bonds decreases.

Signup and view all the flashcards

Saponification

The process of converting fats or oils into soap by reacting them with a strong alkali (like lye) in the presence of water.

Signup and view all the flashcards

Oxidation of Triacylglycerols

The breakdown of triacylglycerol molecules through reaction with oxygen in air. This breaks double bonds and forms aldehydes and carboxylic acids.

Signup and view all the flashcards

What is an enzyme?

Enzymes are specialized proteins that act as catalysts in biological reactions. They speed up processes without being consumed themselves, making reactions happen much faster.

Signup and view all the flashcards

Enzymes and their characteristics

Enzymes are typically proteins that accelerate reactions. They are not consumed by the reaction and are regenerated. They are highly specific to their substrates.

Signup and view all the flashcards

Fatty Acid Chain Length

The number of carbon atoms in a fatty acid chain. Longer chains have more Van der Waals forces, leading to higher melting points.

Signup and view all the flashcards

Fatty Acid Saturation

The presence or absence of double bonds in a fatty acid chain. Saturated fats have only single bonds, while unsaturated fats have double bonds.

Signup and view all the flashcards

Melting Point & Unsaturation

Unsaturated fatty acids have lower melting points than saturated fatty acids due to the presence of double bonds, which disrupt the ordered packing of molecules.

Signup and view all the flashcards

Good Cholesterol (HDL)

High-density lipoprotein, which transports excess cholesterol from tissues back to the liver for processing or excretion.

Signup and view all the flashcards

What increases melting point?

Longer fatty acid chains and a higher degree of saturation (more single bonds) both increase the melting point of a fatty acid.

Signup and view all the flashcards

Medium Chain Fatty Acids

Fatty acids with 6 to 12 carbon atoms. They have moderate solubility and melting points.

Signup and view all the flashcards

Long Chain Fatty Acids

Fatty acids with more than 12 carbon atoms. They are generally insoluble in water and have relatively high melting points.

Signup and view all the flashcards

What are the types of fatty acids?

Fatty acids are classified by their chain length and saturation. Short chain (less than 6 carbons), medium chain (6 to 12 carbons), and long chain (greater than 12 carbons). Unsaturated fats have one or more double bonds, monounsaturated (one double bond) and polyunsaturated (two or more double bonds).

Signup and view all the flashcards

Melting Point & Chain Length

Longer fatty acid chains have higher melting points. This is because longer chains allow for more van der Waals forces to form, increasing the intermolecular attraction.

Signup and view all the flashcards

Bad cholesterol (LDL)

Low-density lipoprotein is a type of cholesterol that transports cholesterol to tissues. High levels of LDL cholesterol can increase the risk of heart disease.

Signup and view all the flashcards

Sphingosine

A long-chain amino alcohol that forms the backbone of sphingolipids.

Signup and view all the flashcards

What is the function of glycolipids?

Glycolipids are important for cell recognition and signaling.

Signup and view all the flashcards

Substrate

The reactant that is activated and undergoes a chemical change by an enzyme.

Signup and view all the flashcards

Study Notes

DNA vs RNA

  • DNA is found in the cell nucleus
  • DNA stores and transfers genetic information
  • DNA is passed from existing cells to new cells during cell division
  • RNA occurs in all parts of a cell
  • RNA's primary function is protein synthesis

Purines vs Pyrimidines

  • Five nitrogenous bases exist
  • Purines are double ring structures (Guanine, Adenine)
  • Pyrimidines are single ring structures (Cytosine, Thymine, Uracil)
  • Guanine and Adenine are found in both DNA and RNA
  • Cytosine is found in both DNA and RNA
  • Thymine is found in DNA
  • Uracil is found in RNA

Nucleoside Formation

  • Nitrogenous base is connected to C1 of the sugar
  • C2 of the sugar is differentiated by H or OH
  • C5 is where the phosphate is attached

Structural Characteristics of DNA

  • DNA consists of two anti-parallel polynucleotides
  • One strand runs 5' to 3', the other runs 3' to 5'
  • Sugar-phosphate backbone is on the outside
  • Hydrophobic bases are on the inside

Base Pairing

  • A pyrimidine pairs with a purine
  • A pairs with T (two hydrogen bonds)
  • G pairs with C (three hydrogen bonds)

DNA Replication

  • Helicase unwinds the DNA helix
  • Primase adds RNA primers
  • Polymerase III copies the DNA strands
  • Polymerase I replaces RNA primers with DNA nucleotides
  • Ligase seals the DNA segments

Transcription

  • Process of copying DNA segment to RNA
  • DNA segments that produce messenger RNA (mRNA) encode proteins

Types of RNA

  • Ribosomal RNA (rRNA)
  • Most abundant
  • Structural component of ribosomes
  • Transfer RNA (tRNA)
  • Second most abundant
  • Carries amino acids to ribosomes
  • Messenger RNA (mRNA)
  • Carries information to ribosomes, specifying amino acid sequence
  • Only type of RNA that is translated

Translation

  • mRNA is translated into protein
  • Codon: a sequence of three mRNA nucleotides that codes for an amino acid
  • The order of codons determines the order of amino acids
  • Start codon: AUG (methionine)
  • Stop codons: UAA, UAG, UGA

Central Dogma

  • Replication: DNA makes identical copies of DNA
  • Transcription: DNA makes RNA
  • Translation: RNA makes proteins

Mutations

  • Changes in the DNA sequence at a particular gene locus
  • Can be harmful, beneficial, or neutral

Point Mutations

  • Silent mutation: no change in protein activity
  • Missense mutation: one amino acid substituted
  • Nonsense mutation: premature stop codon, shortened protein
  • Frameshift mutation: addition or deletion of DNA bases, altered reading frame

Polymerase Chain Reaction (PCR)

  • Technique to make many copies of a specific DNA region
  • Steps: denaturation, annealing, extension

Lipids

  • Insoluble or sparingly soluble in water
  • Soluble in nonpolar organic solvents
  • Types of lipids include triacylglycerols, phospholipids, sphingolipids, waxes, steroids, and terpenes
  • Classified by solubility

Fatty Acids

  • Members of carboxylic acids
  • Hydrocarbon chain with a terminal carboxyl group (COOH)
  • Saturated fatty acids: solid at room temperature
  • Unsaturated fatty acids: liquid at room temperature

Prostaglandins

  • c20 fatty-acid derivatives
  • Involved in raising body temperature, inhibiting gastric juices, increasing mucus secretion.

Thormboxanes

  • c20 fatty-acid derivatives
  • Promote platelet aggregation (blood clotting)

Leukotrienes

  • c20 fatty-acid derivatives
  • Promote inflammation

Higher Unsaturated Fatty Acids (UFAs)

  • HUFA: Polyunsaturated fatty acids with greater than 20 carbon atoms
  • Essential for proper neural and visual function

Essential Fatty Acids (EFAs)

  • Cannot be synthesized by animals.
  • Must be obtained from diet
  • EFA n-6 and n-3

Cholesterol

  • Major steroid in the body
  • Precursor to bile salts, steroid hormones

Protein Denaturation

  • Loss of a protein's natural shape and function
  • Factors that cause denaturation:
  • Heat
  • Alcohol
  • Acids
  • Inorganic chemicals
  • Organic chemicals
  • Alkalis

Chemical Reactions of Triacylglycerols

  • Hydrolysis: breakdown with water (lipases)
  • Saponification: breakdown with base (produces soap)

Protein Structural Organization

  • Primary structure: linear sequence of amino acids
  • Secondary structure: local folding patterns (alpha helix, beta sheet)
  • Tertiary structure: overall 3D shape
  • Quaternary structure: interactions between multiple polypeptide chains

Peptide Bonds

  • Bonds that link amino acids in a polypeptide chain
  • Formed by condensation reaction (loss of water)

Enzymes

  • Protein catalysts that accelerate chemical reactions
  • Types:
    • Oxidoreductases
    • Transferases
    • Hydrolases
    • Lyases
    • Isomerases
    • Ligases

Enzyme Activity Factors

  • Temperature
  • pH
  • Substrate Concentration
  • Enzyme Concentration
  • Inhibitors/Activators

Isoelectric Point (pI)

  • pH at which an amino acid has no net charge (zwitterion)

Stereochemistry of Amino Acids

  • Chiral amino acids (except glycine) exist as L or D isomers
  • Proteins generally utilize L-amino acids

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

Description

Test your knowledge on the fundamental differences between DNA and RNA, as well as their respective roles in genetic information and protein synthesis. Dive into the details of nucleoside formation, structural characteristics of DNA, and the base pairing rules. Perfect for biology students wanting to reinforce their understanding of nucleic acids.

More Like This

Nucleic Acids and DNA
45 questions

Nucleic Acids and DNA

SparklingLoyalty avatar
SparklingLoyalty
DNA & RNA Structure and Function
34 questions
Biology Nucleic Acids Overview
5 questions

Biology Nucleic Acids Overview

FaultlessSnowflakeObsidian1806 avatar
FaultlessSnowflakeObsidian1806
Nucleic Acids and DNA Replication
38 questions
Use Quizgecko on...
Browser
Browser