Podcast
Questions and Answers
Carbohydrates and Lipids can self-replicate.
Carbohydrates and Lipids can self-replicate.
False (B)
What is the main effect of histone acetylation on chromatin packing?
What is the main effect of histone acetylation on chromatin packing?
Loosens packing
Which of the following statements is TRUE about histone methylation?
Which of the following statements is TRUE about histone methylation?
- It always leads to tighter chromatin packing.
- It has no effect on chromatin packing.
- It can have both loosening and tightening effects, depending on the specific methylation site. (correct)
- It always leads to looser chromatin packing.
The enzyme that adds acetyl groups to histone proteins is called a ______.
The enzyme that adds acetyl groups to histone proteins is called a ______.
Match the following molecules with their primary location within a cell:
Match the following molecules with their primary location within a cell:
Which of the following DNA sequences is complementary to 5'-TAGAC-3'?
Which of the following DNA sequences is complementary to 5'-TAGAC-3'?
DNA in eukaryotic cells is organized into circular chromosomes and located in the nucleus.
DNA in eukaryotic cells is organized into circular chromosomes and located in the nucleus.
Which of the following is NOT a characteristic of DNA organization in eukaryotes?
Which of the following is NOT a characteristic of DNA organization in eukaryotes?
Condensins decondense chromosomes after mitosis.
Condensins decondense chromosomes after mitosis.
Nucleosomes coil and stack into ______ chromatin fibers.
Nucleosomes coil and stack into ______ chromatin fibers.
In a diploid organism with a haploid number (n) of 4 chromosomes, how many chromosomes are present in somatic cells? How many chromosomes are present in mature gamete cells?
In a diploid organism with a haploid number (n) of 4 chromosomes, how many chromosomes are present in somatic cells? How many chromosomes are present in mature gamete cells?
Match the following nitrogenous bases with their correct category.
Match the following nitrogenous bases with their correct category.
List four classes of macromolecules that were once considered possible carriers of genetic information.
List four classes of macromolecules that were once considered possible carriers of genetic information.
Which of the following is the most complete and correct definition of a gene?
Which of the following is the most complete and correct definition of a gene?
Mendel's law of segregation explains that the alleles for one gene (Aa) and the alleles for another gene (Bb) will be found in equal proportions in the offspring.
Mendel's law of segregation explains that the alleles for one gene (Aa) and the alleles for another gene (Bb) will be found in equal proportions in the offspring.
The temperature that causes hydrogen bonds between bases to break is referred to as the ______.
The temperature that causes hydrogen bonds between bases to break is referred to as the ______.
What is the role of topoisomerases in DNA replication?
What is the role of topoisomerases in DNA replication?
Match the following terms with their definitions:
Match the following terms with their definitions:
Which of the following statements is true about Tm?
Which of the following statements is true about Tm?
Topoisomerases are only found in bacteria, not eukaryotes.
Topoisomerases are only found in bacteria, not eukaryotes.
According to Mendel's law of ______, if the parent genotype is Aa, the probability of getting allele A or allele a in a gamete is equally likely.
According to Mendel's law of ______, if the parent genotype is Aa, the probability of getting allele A or allele a in a gamete is equally likely.
Flashcards
Gene definition
Gene definition
A specific segment of DNA in a discrete region of a chromosome that codes for a functional product.
Mendel's Law of Independent Assortment
Mendel's Law of Independent Assortment
Alleles for one gene segregate independently of alleles for another gene during gamete formation.
Mendel's Law of Segregation
Mendel's Law of Segregation
Each individual has two alleles for each gene, which segregate into gametes with equal probability.
Tm (melting temperature)
Tm (melting temperature)
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Topoisomerases
Topoisomerases
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Role of DNA in proteins
Role of DNA in proteins
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Gamete formation
Gamete formation
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Hydrogen bonds in DNA
Hydrogen bonds in DNA
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Carbohydrates
Carbohydrates
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Proteins
Proteins
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Nucleic Acids
Nucleic Acids
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Role of Acetylation in Histone Modification
Role of Acetylation in Histone Modification
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Role of Methylation in Histone Modification
Role of Methylation in Histone Modification
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Complementary DNA Sequence
Complementary DNA Sequence
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DNA Organization in Eukaryotes
DNA Organization in Eukaryotes
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Nucleosomes
Nucleosomes
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Chromatin Packaging
Chromatin Packaging
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Diploid Chromosome Count
Diploid Chromosome Count
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Pyrimidines
Pyrimidines
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Purines
Purines
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Macromolecules in Cells
Macromolecules in Cells
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Study Notes
DNA, Chromosomes, Structure
- Gene Definition: A specific segment of DNA within a chromosome that codes for a functional product, usually a protein.
- Mendel's Law of Independent Assortment: The probability of inheriting one allele from a parent is equally likely for any given allele.
- Mendel's Law of Segregation: In gamete formation, the alleles for a given gene separate, and each gamete receives only one allele.
- DNA Structure: Double helix; nitrogenous bases (adenine, guanine, cytosine, and thymine) paired together.
- Topoisomerases: Enzymes that modify DNA structure by adding or removing twists, facilitating DNA replication and compaction.
- Denaturation Temperature: The temperature at which DNA's phosphodiester or hydrogen bonds break. The higher the GC content, the higher the denaturation temperature.
- Eukaryotic DNA Organization: DNA is associated with proteins (histones) to form a complex called chromatin, highly organized into specific regions within the nucleus.
- Eukaryotic Chromatin Structure: DNA segments are organized into nucleosome structures, coiled and stacked into 30nm chromatin fibers.
- Chromosome Packaging: Chromosomes condense extensively before cell division.
- Complementary DNA Sequence: The complementary sequence to 5'-TAGAC-3' is 5'-ATCTG-3'.
- DNA bases: Cytosine, adenine, guanine, thymine, uracil.
- Pyrimidines: Single-ring structures (Cytosine, thymine, uracil)
- Purines: Double-ring structures (Adenine, guanine)
- Somatic Cells: Diploid cells with 8 chromosomes in this example.
- Mature Gamete Cells: Haploid cells with 4 chromosomes in this example.
Histone Modification
- Acetylation: Neutralizes positive charge on histones, allowing chromatin to loosen.
- Methylation: Histone modification without charge alteration, causing chromatin compaction sometimes.
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