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Questions and Answers
What is a karyotype?
What is a karyotype?
How many sex chromosomes do females have?
How many sex chromosomes do females have?
What is the primary purpose of mitosis?
What is the primary purpose of mitosis?
What do the terms haploid and diploid refer to?
What do the terms haploid and diploid refer to?
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Which statement is true regarding meiosis?
Which statement is true regarding meiosis?
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What is the structure of a chromosome?
What is the structure of a chromosome?
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What is the function of chromosomal staining in research?
What is the function of chromosomal staining in research?
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Which process is involved in the production of sperm and eggs?
Which process is involved in the production of sperm and eggs?
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What is the primary result of spermatogenesis in males?
What is the primary result of spermatogenesis in males?
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During spermatogenesis, when does the first meiotic division occur?
During spermatogenesis, when does the first meiotic division occur?
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What is the role of Sertoli cells in spermatogenesis?
What is the role of Sertoli cells in spermatogenesis?
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Which stage of spermatogenesis involves the reduction of chromosome number?
Which stage of spermatogenesis involves the reduction of chromosome number?
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How does oogenesis differ from spermatogenesis in terms of lifespan?
How does oogenesis differ from spermatogenesis in terms of lifespan?
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What type of cell does a 'type A' spermatogonium remain as?
What type of cell does a 'type A' spermatogonium remain as?
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What is the chromosome number of secondary spermatocytes?
What is the chromosome number of secondary spermatocytes?
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At what point in spermatogenesis do spermatids form?
At what point in spermatogenesis do spermatids form?
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What is the primary outcome of oogenesis?
What is the primary outcome of oogenesis?
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Which structure contains the primary oocyte and surrounding follicular cells?
Which structure contains the primary oocyte and surrounding follicular cells?
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How many primary oocytes approximately remain at puberty?
How many primary oocytes approximately remain at puberty?
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During which meiotic stage do primary oocytes remain arrested from intrauterine life until sexual maturity?
During which meiotic stage do primary oocytes remain arrested from intrauterine life until sexual maturity?
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What initiates the maturation of ovarian follicles after puberty?
What initiates the maturation of ovarian follicles after puberty?
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What is produced from the first meiotic division of the primary oocyte?
What is produced from the first meiotic division of the primary oocyte?
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Which glands contribute to the production of seminal fluid?
Which glands contribute to the production of seminal fluid?
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What is the function of the first polar body formed during oogenesis?
What is the function of the first polar body formed during oogenesis?
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What characterizes the secondary follicle during maturation?
What characterizes the secondary follicle during maturation?
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What happens to the secondary oocyte during fertilization?
What happens to the secondary oocyte during fertilization?
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Which layer of the Graafian follicle is responsible for estrogen hormone production?
Which layer of the Graafian follicle is responsible for estrogen hormone production?
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What structure separates the granulosa cells from the oocyte?
What structure separates the granulosa cells from the oocyte?
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When does ovulation typically occur in relation to the menstrual cycle?
When does ovulation typically occur in relation to the menstrual cycle?
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What is the role of the stratum granulosum in the Graafian follicle?
What is the role of the stratum granulosum in the Graafian follicle?
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What occurs immediately after the Graafian follicle ruptures?
What occurs immediately after the Graafian follicle ruptures?
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Which event is NOT a feature of the primary follicle's development?
Which event is NOT a feature of the primary follicle's development?
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What initiates the maturation of the primordial follicle during the follicular phase?
What initiates the maturation of the primordial follicle during the follicular phase?
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What happens to the Graafian follicle during ovulation?
What happens to the Graafian follicle during ovulation?
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What hormone increases in the blood during the luteal phase?
What hormone increases in the blood during the luteal phase?
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What is the effect of estrogen and progesterone on F.S.H. during the luteal phase?
What is the effect of estrogen and progesterone on F.S.H. during the luteal phase?
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What occurs to the corpus luteum if fertilization does not take place?
What occurs to the corpus luteum if fertilization does not take place?
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What triggers the onset of a new ovarian cycle?
What triggers the onset of a new ovarian cycle?
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During which phase does menstrual blood flow occur?
During which phase does menstrual blood flow occur?
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What is the duration of the menstrual cycle?
What is the duration of the menstrual cycle?
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Study Notes
Karyotype
- A karyotype is an image displaying an individual's chromosomes lined up in pairs
- The 22 autosomes are numbered by size, and the sex chromosomes are X and Y
- Karyotypes are used to analyze the number and structure of chromosomes for abnormalities
Chromosomes
- Chromosomes are thread-like structures found in the nucleus of animal and plant cells
- Chromosomes are made of protein and DNA
- DNA contains the instructions that make each organism unique
- Each chromosome is made up of two chromatids connected by a centromere
Mitosis
- Mitosis is a type of cell division where one cell divides into two identical daughter cells
- Mitosis is essential for growth and replacing worn-out cells
Meiosis
- Meiosis is a process where a single cell divides twice to produce four cells with half the original amount of genetic information
- Meiosis produces our sex cells (sperm in males, eggs in females)
- These cells are called gametes and are haploid, meaning they have half the number of chromosomes as the parent cell
Spermatogenesis
- Spermatogenesis is the process of producing sperm from primitive sex cells called spermatogonia
- Spermatogenesis is a continuous process from puberty to old age
- Spermatogonia are the most primitive sex cells and divide by mitosis
- Type B spermatogonia mature into primary spermatocytes, which have 46 chromosomes
- Primary spermatocytes undergo meiosis I, resulting in two secondary spermatocytes (23 chromosomes each)
- Secondary spermatocytes undergo meiosis II, producing two spermatids (23 chromosomes each)
- Spermiogenesis is the transformation of spermatids into mature sperm by Sertoli cells
Oogenesis
- Oogenesis is the process of producing mature eggs (ova) from primitive sex cells called oogonia
- Oogenesis is a cyclic process occurring once every month, unlike the continuous process of spermatogenesis
- Oogonia are present in the ovary early in intrauterine life
- Most oogonia degenerate, and the surviving ones become primary oocytes
- Primary oocytes are arrested in the prophase stage of meiosis I until sexual maturity
- Each primary oocyte is surrounded by a layer of flat follicular cells, forming a primordial follicle
- Primordial follicles remain dormant until puberty when they start to mature
- The total number of primary oocytes decreases from about 1,000,000 at birth to roughly 40,000 at puberty
- Oogenesis takes place in the cortex of the ovary, and only one ovarian follicle matures each month
Steps of Oogenesis
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Maturation of the primordial follicle:
- The primary oocyte undergoes meiosis I, resulting in a secondary oocyte (23 chromosomes) and a polar body (23 chromosomes)
- The follicular cells surrounding the oocyte divide mitotically, forming multiple layers called granulosa cells
- The granulosa cells are separated from the oocyte by a thick hyaline membrane called the zona pellucida
- Cavities filled with fluid appear between granulosa cells, forming a single cavity called the follicular antrum
- The antrum separates the granulosa cells into two layers: the stratum granulosum (outer layer) and the inner layer, which surrounds the secondary oocyte as the cumulus oophorus
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Formation of the mature (Graafian) follicle:
- Pressure increases inside the antrum
- A sheath of stroma cells forms around the follicle, called the theca follicle
- The theca is divided into the theca externa (outer layer) and theca interna (inner layer)
- The theca interna is the main source of estrogen hormone
-
Rupture of Graafian follicle (ovulation):
- The mature Graafian follicle ruptures through the thin and ischemic cortex of the ovary
- This occurs around 14 days before the following menstrual cycle
- The secondary oocyte, surrounded by the zona pellucida and corona radiata, is discharged from the ovary and enters the uterine tube
- The rupture is facilitated by factors such as the increased pressure inside the antrum and the action of hormones
Phases of the Menstrual Cycle
-
Follicular phase:
- Starts on the first day of menstrual flow
- Follicle-stimulating hormone (FSH) from the pituitary gland initiates primordial follicle maturation into the Graafian follicle
- Estrogen hormone is secreted by the theca interna cells of the Graafian follicle
-
Ovulation Day 14:
- The Graafian follicle ruptures, and the ovum is released into the uterine tube
- The wall of the Graafian follicle transforms into the corpus luteum
-
Luteal phase:
- Formation of the corpus luteum under the influence of luteinizing hormone (LH) from the pituitary gland
- Progesterone hormone levels increase, while estrogen levels decrease
- Estrogen and progesterone suppress FSH secretion, preventing further follicle maturation within the same cycle
- They also induce proliferation and glandular activity in the endometrium of the uterus
- At the end of the ovarian cycle, the corpus luteum degenerates, leading to decreased estrogen and progesterone levels
- This allows FSH release, initiating a new ovarian cycle
- If fertilization occurs, the corpus luteum remains active for a longer period, and the ovarian cycles stop until after childbirth
Menstrual Cycle
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The menstrual cycle is a series of changes in the endometrium of the uterus, occurring monthly under the influence of ovarian hormones
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It lasts for 28 days, beginning with menstrual blood flow
-
It consists of three phases:
-
Menstrual flow phase:
- Menstrual blood flow lasts for approximately 3-5 days
- The blood flow is about 50 cc and contains:
- Blood
- Cells from the endometrium of the uterus
- Mucus
- Tissue fluids
-
Menstrual flow phase:
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Description
Explore the fundamentals of karyotypes, chromosomes, mitosis, and meiosis in this engaging quiz. Understand how these processes contribute to genetic diversity and the importance of cell division in growth and reproduction. Test your knowledge on the structure and function of chromosomes and their role in heredity.