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Questions and Answers
What role do mutations in genes play in a population?
What role do mutations in genes play in a population?
Which type of bond involves the transfer of electrons between atoms?
Which type of bond involves the transfer of electrons between atoms?
What is a characteristic of polar molecules?
What is a characteristic of polar molecules?
Which functional group is represented by the formula -CHO?
Which functional group is represented by the formula -CHO?
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What is the primary function of the Golgi apparatus in a eukaryotic cell?
What is the primary function of the Golgi apparatus in a eukaryotic cell?
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Which component of a prokaryotic cell is responsible for allowing bacteria to attach to surfaces?
Which component of a prokaryotic cell is responsible for allowing bacteria to attach to surfaces?
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Which of the following correctly describes the pH scale?
Which of the following correctly describes the pH scale?
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Which organelle is primarily involved in ATP synthesis?
Which organelle is primarily involved in ATP synthesis?
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Which domain includes organisms with prokaryotic cells?
Which domain includes organisms with prokaryotic cells?
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What is the role of the cytoskeleton in eukaryotic cells?
What is the role of the cytoskeleton in eukaryotic cells?
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What does Mendel's Law of Segregation state about alleles during gamete formation?
What does Mendel's Law of Segregation state about alleles during gamete formation?
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In a monohybrid cross of Tt x Tt, what is the expected phenotypic ratio?
In a monohybrid cross of Tt x Tt, what is the expected phenotypic ratio?
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Which of the following best describes codominance?
Which of the following best describes codominance?
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What does the dihybrid cross of AABB x aabb produce in the F1 generation?
What does the dihybrid cross of AABB x aabb produce in the F1 generation?
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What is an example of polygenic inheritance?
What is an example of polygenic inheritance?
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Which process describes the effect where multiple genes influence a single trait?
Which process describes the effect where multiple genes influence a single trait?
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What is meant by linkage in genetics?
What is meant by linkage in genetics?
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What occurs during X chromosome inactivation?
What occurs during X chromosome inactivation?
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What is the primary function of the plasma membrane?
What is the primary function of the plasma membrane?
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Which of the following best describes passive transport?
Which of the following best describes passive transport?
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In glycolysis, what is the net gain of ATP produced from one molecule of glucose?
In glycolysis, what is the net gain of ATP produced from one molecule of glucose?
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Which reaction occurs during the transition state in an enzyme-catalyzed reaction?
Which reaction occurs during the transition state in an enzyme-catalyzed reaction?
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What is the role of cyclic AMP (cAMP) in cellular signaling?
What is the role of cyclic AMP (cAMP) in cellular signaling?
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What is produced during anaerobic respiration in yeast cells?
What is produced during anaerobic respiration in yeast cells?
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What is the function of the porphyrin ring in chlorophyll?
What is the function of the porphyrin ring in chlorophyll?
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What is the consequence of the domino effect during anaerobic respiration?
What is the consequence of the domino effect during anaerobic respiration?
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Which is NOT a characteristic of the G-protein-coupled receptors (GPCRs)?
Which is NOT a characteristic of the G-protein-coupled receptors (GPCRs)?
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In the Calvin Cycle, what compound is fixed in the carbon fixation process?
In the Calvin Cycle, what compound is fixed in the carbon fixation process?
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How do enzymes specifically bind to their substrates?
How do enzymes specifically bind to their substrates?
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Which of the following statements about DNA structure is correct?
Which of the following statements about DNA structure is correct?
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What does the Meselson-Stahl experiment demonstrate about DNA replication?
What does the Meselson-Stahl experiment demonstrate about DNA replication?
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What is served by the structure of the promoter in DNA?
What is served by the structure of the promoter in DNA?
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What is the role of the 5' cap in mRNA?
What is the role of the 5' cap in mRNA?
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Which phase of the cell cycle involves the replication of DNA?
Which phase of the cell cycle involves the replication of DNA?
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What primarily provides a signal for the transition from metaphase to anaphase?
What primarily provides a signal for the transition from metaphase to anaphase?
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Which type of RNA directly carries amino acids during translation?
Which type of RNA directly carries amino acids during translation?
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What happens during the process of transcription termination?
What happens during the process of transcription termination?
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What is the significance of crossing over during meiosis?
What is the significance of crossing over during meiosis?
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What is the function of the ribosomal-binding site in mRNA?
What is the function of the ribosomal-binding site in mRNA?
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Which cellular structure is responsible for the removal of introns from pre-mRNA?
Which cellular structure is responsible for the removal of introns from pre-mRNA?
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What is the primary error-checking mechanism in the cell cycle?
What is the primary error-checking mechanism in the cell cycle?
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In which phase of mitosis do sister chromatids align at the metaphase plate?
In which phase of mitosis do sister chromatids align at the metaphase plate?
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What cellular event occurs during telophase in mitosis?
What cellular event occurs during telophase in mitosis?
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During which phase of the cell cycle do cyclin D and E synthesis occur?
During which phase of the cell cycle do cyclin D and E synthesis occur?
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What is the role of amino acid transferase in protein synthesis?
What is the role of amino acid transferase in protein synthesis?
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Study Notes
Mechanisms of Evolution
- Vertical descent with mutations: Mutations in genes create diversity within a population. Genes for advantageous traits become more common in subsequent generations.
- Horizontal gene transfer: Genetic material is exchanged between different organisms (e.g., plants to animals).
Phylogenetic Trees and Classification
- Phylogenetic trees illustrate evolutionary relationships among groups.
- Taxonomy uses evolutionary relationships to categorize organisms.
- Principle categories: Domain (bacteria, archaea, eukarya), Kingdoms (plants, protists, fungi, animals), Phylum, Class, Order, Family, Genus (capitalized), Species (underlined).
Chemical Bonding and Water Properties
- Covalent Bonds: Atoms share electrons to form stable electron pairs.
- Ionic Bonds: Atoms transfer electrons.
- Polarity: Unequal electron sharing creates partial charges (mainly in nitrogen and oxygen).
- Hydrophilic: Substances attracted to water (polar).
- Hydrophobic: Substances repelled by water (nonpolar).
- Water as a Solvent: Water dissolves solutes with similar properties ("like dissolves like"). Hydrophilic compounds (polar) dissolve in water; hydrophobic compounds (nonpolar) do not.
- pH: Measures acidity or basicity. Water dissociates into H+ and OH-. pH 7 is neutral. Higher numbers indicate basicity; lower numbers indicate acidity. Acids release H+ in water; bases accept H+.
Functional Groups
- Amino (-NH2)
- Carbonyl (Ketone -CO, Aldehyde -CHO)
- Carboxyl (-COOH)
- Hydroxyl (-OH)
- Methyl (-CH3)
- Phosphate (-PO4 2-)
Prokaryotic and Eukaryotic Cell Structures
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Prokaryotic:*
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Pili: Attachment to surfaces/each other.
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Cytoplasm: Metabolic site.
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Ribosomes: Synthesize polypeptides.
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Nucleoid: DNA location.
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Plasma membrane: Encloses cytoplasm.
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Cell wall: Support and protection.
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Glycocalyx: Gelatinous outer covering.
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Flagella: Movement.
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Eukaryotic:*
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Centrosome: Microtubule growth and centriole location.
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Rough ER: Protein sorting/secretion.
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Smooth ER: Detoxification/lipid synthesis.
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Mitochondria: ATP synthesis.
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Cytoskeleton: Protein filaments for shape and movement.
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Peroxisome: Breakdown of harmful molecules.
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Golgi apparatus: Modification, sorting, and secretion of lipids/proteins.
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Cytosol: Site of many metabolic pathways.
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Plasma membrane: Controls substance movement, cell signaling.
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Ribosomes: Polypeptide synthesis.
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Lysosomes: Macromolecules degradation.
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Nuclear envelope: Double membrane surrounding the nucleus.
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Nucleus: Passageway for molecules
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Nuclear pore: Passageway for molecules into/out of nucleus.
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Endosymbiotic theory: Mitochondria and chloroplasts originated from engulfed prokaryotes.
Plasma Membrane and Transport
- Plasma membrane: Selectively permeable phospholipid bilayer. Controls movement of molecules.
- Passive transport: Movement down a concentration gradient (no energy required).
- Active transport: Movement against a concentration gradient (requires energy).
Enzyme Mechanisms
- Enzymes reduce activation energy for reactions.
- Substrates bind to active sites (specific).
- Enzymes catalyze reactions by pushing substrates toward products.
- Steps of enzyme-catalyzed reactions: substrate binding, conformational change, product formation, product release.
Aerobic Respiration
- Glycolysis: Glucose (6C) → 2 pyruvates (3C), producing 2 ATP and 2 NADH in the cytoplasm.
- Pyruvate oxidation: Pyruvate → Acetyl CoA (2C), producing CO2 and NADH.
- Citric acid cycle: Acetyl CoA → 2 ATP, 6 NADH, 2 FADH2.
- Oxidative phosphorylation (ETC): Electron transport chain and ATP synthesis; ATP production from electron transport.
Anaerobic Respiration and Fermentation
- Anaerobic respiration: Alternatives to oxygen as final electron acceptors (e.g., nitrate).
- Fermentation: Only glycolysis occurs; pyruvate is reduced to lactic acid (humans) or ethanol (yeast/bacteria).
Photosynthesis: Light-Dependent and Calvin Cycle
- Light-dependent reactions: Light absorption by pigments (chlorophyll a absorbs red, violet, and blue light; reflects green). Electrons are ejected.
- Calvin Cycle: Carbon fixation (CO2 + RuBP → 3PGA), reduction (ATP + NADPH used to convert 3PGA to sugars), regeneration of RuBP.
Cellular Receptors
- Enzyme-linked receptors: Often kinases; often involve phosphorylation cascades (e.g., receptor tyrosine kinases).
- G protein-coupled receptors (GPCRs): 7 transmembrane domains; G protein activation; second messenger signaling (e.g., cAMP).
- Ligand-gated ion channels: Channels open/close in response to ligands.
DNA Structure and Replication
- DNA structure: Double helix; nucleotides (A, T, G, C).
- Chargaff's rule: %A = %T, %G = %C.
- Watson and Crick's model: Used Franklin's X-ray data.
- DNA replication: Semiconservative (each original strand serves as a template for a new strand).
- PCR (Polymerase Chain Reaction): Amplifies DNA segments; steps: denaturation, annealing, extension.
- Sanger sequencing: Determines DNA sequence.
Transcription
- Gene structure: Promoter, transcribed region, terminator, regulatory sequences.
- Transcription process: RNA polymerase binds promoter, elongation (complementary RNA strand built), termination.
- RNA modifications: 5' cap and 3' poly-A tail for stability and translation signals. Removal of introns via spliceosomes.
Translation
- mRNA structure: Ribosomal binding site (prokaryotes only), start codon (AUG), coding sequence, stop codon. Codons code for amino acids (degenerate code).
- tRNA structure: Cloverleaf model; anticodon; amino acid attachment site.
- Ribosome structure and composition: Composed of RNA and proteins; have A, P, and E sites. Bacterial (70S) and eukaryotic (80S) ribosomes.
Lac Operon Regulation
- Lac operon: Bacterial gene regulation of lactose metabolism. Regulated by a repressor protein.
Eukaryotic Cell Cycle
- Cell cycle phases: G1, S, G2, M (mitosis).
- G0 phase: Non-dividing cells.
- Cyclins and CDKs: Regulate the cell cycle.
- Checkpoints: Control points in the cell cycle (G1, G2, M). p53 regulates these checks.
- Proto-oncogenes and tumor suppressor genes: Control cell division.
- Mitosis and cytokinesis: Process of cell division.
- Meiosis: Cell division for gamete formation.
Mendelian Genetics
- Mendel's laws of segregation and independent assortment.
- Monohybrid and dihybrid crosses.
- Extensions of Mendel's laws: incomplete dominance, codominance, environmental influence, pleiotropy, epistasis, polygenic inheritance.
- Linkage and extranuclear inheritance (mitochondria, chloroplasts).
- Epigenetic inheritance (X chromosome inactivation).
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Description
This quiz covers mechanisms of evolution, including vertical descent with mutations and horizontal gene transfer. Additionally, it explores phylogenetic trees, taxonomy, and the basic principles of chemical bonding and properties of water. Test your knowledge on how these concepts are interrelated in biology.