W9_Cell Structure and Function(medium+hard)

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary function of flagella in prokaryotic cells?

  • Cell division
  • Protein synthesis
  • Nutrient absorption
  • Locomotion (correct)

What distinguishes Gram-positive bacteria from Gram-negative bacteria?

  • Gram-negative bacteria have no cell wall.
  • Gram-negative bacteria always cause disease.
  • Gram-positive bacteria have a thinner cell wall.
  • Gram-positive bacteria stain purple due to a thicker peptidoglycan layer. (correct)

Which characteristic is exclusive to eukaryotic cells?

  • Undergoing binary fission
  • Containing peptidoglycan
  • Having a membrane-bound nucleus (correct)
  • Possessing a cytoskeleton

What component is not part of the general structure of a cell?

<p>Ribosome (A)</p> Signup and view all the answers

What is the content of the cytoplasm composed of?

<p>Cytosol and organelles (D)</p> Signup and view all the answers

Which of the following cell types does not belong to the category of eukaryotic cells?

<p>Bacteria (D)</p> Signup and view all the answers

What is the function of the cytoskeleton in eukaryotic cells?

<p>Support and maintenance of cellular structure (B)</p> Signup and view all the answers

Gram-negative bacteria are characterized by which of the following?

<p>Thin peptidoglycan layer (A)</p> Signup and view all the answers

What is the primary function of cells according to the cell theory?

<p>Cells are the smallest units that perform all vital physiological functions. (C)</p> Signup and view all the answers

What is the estimated number of cells in the human body?

<p>About 3.72x10^13 cells (D)</p> Signup and view all the answers

Which of the following statements regarding various cell types in the human body is accurate?

<p>The human body comprises over 200 different types of cells. (B)</p> Signup and view all the answers

Which of the following is NOT a part of the cell theory?

<p>Cells can spontaneously generate from non-living matter. (C)</p> Signup and view all the answers

What type of cells are neurons classified as?

<p>Nerve cells (D)</p> Signup and view all the answers

Which cell type is primarily responsible for carrying oxygen in the bloodstream?

<p>Erythrocytes (D)</p> Signup and view all the answers

Which of the following cell types is classified as a connective tissue cell?

<p>Osteocytes (D)</p> Signup and view all the answers

What is the role of the plasma membrane in a cell?

<p>It regulates the movement of substances in and out of the cell. (C)</p> Signup and view all the answers

What is the structural composition of centrioles within the centrosome?

<p>9 clusters of 3 microtubules (C)</p> Signup and view all the answers

Which organelle is primarily responsible for protein synthesis?

<p>Ribosomes (A)</p> Signup and view all the answers

What is the main function of cilia in the respiratory system?

<p>Move mucus (B)</p> Signup and view all the answers

What distinguishes rough endoplasmic reticulum from smooth endoplasmic reticulum?

<p>Presence of ribosomes (B)</p> Signup and view all the answers

Which of the following is NOT a function of the smooth endoplasmic reticulum?

<p>Protein synthesis (C)</p> Signup and view all the answers

What role do the basilar bodies play in relation to cilia and flagella?

<p>Provide structural support (C)</p> Signup and view all the answers

What is the primary function of the centrosome during cell division?

<p>Movement of chromosomes (A)</p> Signup and view all the answers

How are ribosomes produced within the cell?

<p>Produced in the nucleolus (B)</p> Signup and view all the answers

How does cholesterol affect membrane fluidity at warm temperatures?

<p>Restrains phospholipid movement (A)</p> Signup and view all the answers

What is the role of glycolipids in the plasma membrane?

<p>Create an asymmetric bilayer (C)</p> Signup and view all the answers

What distinguishes integral membrane proteins from peripheral membrane proteins?

<p>Integral proteins are amphipathic and closely associated with lipids (B)</p> Signup and view all the answers

What is one function of transmembrane proteins?

<p>Transport ions or water across the membrane (A)</p> Signup and view all the answers

Where are peripheral membrane proteins found in relation to the membrane?

<p>Bound to the polar regions of integral proteins (A)</p> Signup and view all the answers

What is the glycoprotein's significance in the plasma membrane?

<p>It helps in the transmission of chemical signals (A)</p> Signup and view all the answers

What is the glycocalyx composed of?

<p>Glycoproteins and glycolipids (C)</p> Signup and view all the answers

How does cholesterol maintain membrane fluidity at cold temperatures?

<p>Prevents tight packing and maintains fluidity (B)</p> Signup and view all the answers

What distinguishes unipotent stem cells from non-stem cells?

<p>Ability to produce only one cell type and self-renew (B)</p> Signup and view all the answers

Which stem cell type can give rise to nearly all cell types derived from any of the three germ layers?

<p>Pluripotent stem cells (C)</p> Signup and view all the answers

What is the primary characteristic of oligopotent stem cells?

<p>They can differentiate into a limited number of closely related cell types. (B)</p> Signup and view all the answers

Which of the following statements about prokaryotic cells is correct?

<p>They are the simplest type of cell. (D)</p> Signup and view all the answers

What is the primary function of cell walls in prokaryotic cells?

<p>To protect the cell and maintain shape (A)</p> Signup and view all the answers

Which of these is NOT a characteristic of all cell types?

<p>Single-celled structure (C)</p> Signup and view all the answers

What is the relationship between totipotent and pluripotent stem cells?

<p>Totipotent cells can develop into a complete organism, while pluripotent cells cannot. (B)</p> Signup and view all the answers

Which type of stem cell can differentiate into a number of cell types, but only those related to each other?

<p>Multipotent stem cells (A)</p> Signup and view all the answers

Which characteristic is unique to ribosomes present in prokaryotic cells?

<p>They do not have a membrane. (D)</p> Signup and view all the answers

What is indicated by asymmetric stem cell division?

<p>A stem cell divides to produce another and a differentiated cell. (B)</p> Signup and view all the answers

What is NOT a function of lysosomes?

<p>Modify proteins into glycoproteins (B)</p> Signup and view all the answers

Which structure is primarily involved in detoxifying harmful substances in the liver?

<p>Peroxisomes (C)</p> Signup and view all the answers

What characterizes the Golgi complex?

<p>Flattened membranes resembling stacks of pita bread (B)</p> Signup and view all the answers

What is the main function of proteasomes?

<p>Digest faulty or unneeded proteins (D)</p> Signup and view all the answers

Which of the following conditions is linked to a missing lysosomal enzyme?

<p>Tay-Sachs disease (D)</p> Signup and view all the answers

What do peroxisomes primarily utilize molecular oxygen for?

<p>Removing hydrogen from organic molecules (C)</p> Signup and view all the answers

Which statement about lysosomes is accurate?

<p>They help in the death of old cells through autolysis. (A)</p> Signup and view all the answers

What is the structure of a proteasome?

<p>Cylindrical barrels containing enzymes (C)</p> Signup and view all the answers

Which type of stem cell is isolated from the inner cell mass of blastocysts?

<p>Embryonic stem cells (A)</p> Signup and view all the answers

What is the primary role of totipotent stem cells in early embryonic development?

<p>To differentiate into embryonic and extraembryonic tissues (D)</p> Signup and view all the answers

What defines the term 'potency' in the context of stem cells?

<p>The potential to differentiate into various cell types (B)</p> Signup and view all the answers

Which type of cells serve as a repair system in adults?

<p>Adult stem cells (C)</p> Signup and view all the answers

Which of the following cell types is primarily involved in gathering information and controlling body functions?

<p>Nerve cells (C)</p> Signup and view all the answers

Which statement accurately describes the function of macrophages?

<p>They fight disease. (C)</p> Signup and view all the answers

What are the three germ layers that stem cells can differentiate into during embryonic development?

<p>Ectoderm, endoderm, and mesoderm (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic of stem cells?

<p>Limited capacity for division (D)</p> Signup and view all the answers

What effect does cholesterol have on membrane fluidity at warm temperatures?

<p>It restrains phospholipid movement. (D)</p> Signup and view all the answers

Which of the following best describes the structure of glycolipids in the plasma membrane?

<p>They contain a polar 'head' and nonpolar 'tails'. (A)</p> Signup and view all the answers

What is a key characteristic of integral membrane proteins?

<p>They can form channels for ion transport. (A)</p> Signup and view all the answers

How do peripheral membrane proteins differ from integral membrane proteins?

<p>They do not associate with the lipid bilayer. (D)</p> Signup and view all the answers

What forms the glycocalyx on the plasma membrane?

<p>Glycoproteins with carbohydrate groups attached. (B)</p> Signup and view all the answers

What role do transmembrane proteins play in the plasma membrane?

<p>They can facilitate the transport of molecules across the membrane. (B)</p> Signup and view all the answers

What effect does cold temperature have on membrane fluidity in relation to cholesterol?

<p>It maintains fluidity by preventing tight packing. (D)</p> Signup and view all the answers

Which stem cell type is capable of producing only its own specific cell type?

<p>Unipotent stem cells (D)</p> Signup and view all the answers

Which statement accurately describes the asymmetry of the plasma membrane?

<p>Glycolipids appear only on the extracellular layer. (C)</p> Signup and view all the answers

What is the defining characteristic of oligopotent stem cells?

<p>Ability to form many types of closely related cells (C)</p> Signup and view all the answers

Which term best describes stem cells that can differentiate into nearly all cell types from the three germ layers?

<p>Pluripotent (B)</p> Signup and view all the answers

What is the primary function of mitochondria in human cells?

<p>ATP production (C)</p> Signup and view all the answers

What structure within the nucleus is primarily involved in ribosome production?

<p>Nucleolus (B)</p> Signup and view all the answers

What key feature distinguishes unipotent cells from other stem cell types?

<p>Self-renewal capability (C)</p> Signup and view all the answers

What is the primary product of symmetric stem cell division?

<p>Two identical stem cells (A)</p> Signup and view all the answers

Which of the following statements about mitochondria is incorrect?

<p>They have a single, flat membrane. (C)</p> Signup and view all the answers

What is contained within the liquid matrix of the mitochondria?

<p>Enzymes (C)</p> Signup and view all the answers

What type of stem cell can only differentiate into a limited number of cell types?

<p>Multipotent stem cells (B)</p> Signup and view all the answers

How many chromosomes does the human genome contain?

<p>46 (C)</p> Signup and view all the answers

Which cell type is at the apex of the hierarchy of hematopoietic differentiation?

<p>Multipotent progenitor cells (B)</p> Signup and view all the answers

What limits the differentiation capacity of pluripotent stem cells compared to totipotent stem cells?

<p>Inability to form a complete organism (D)</p> Signup and view all the answers

The primary function of the Kreb’s cycle within mitochondria is to?

<p>Facilitate the production of electron carriers (D)</p> Signup and view all the answers

Which cell types would you expect to have a higher density of mitochondria?

<p>Muscle cells (D)</p> Signup and view all the answers

How are totipotent stem cells produced?

<p>From the fusion of egg and sperm cells (A)</p> Signup and view all the answers

What are the primary components forming chromatin in the nucleus?

<p>Proteins and DNA (C)</p> Signup and view all the answers

What key feature distinguishes Gram-positive bacteria from Gram-negative bacteria in terms of cell wall composition?

<p>Gram-positive bacteria have a thick layer of peptidoglycan between 50-90% of their cell wall. (A)</p> Signup and view all the answers

Which statement accurately describes the structural differences between prokaryotic and eukaryotic cells?

<p>Eukaryotic cells possess a nucleus, whereas prokaryotic cells do not. (A)</p> Signup and view all the answers

What is the role of flagella in prokaryotic cells?

<p>To enable locomotion through rotary motion. (D)</p> Signup and view all the answers

In which way do Gram-negative bacteria respond differently to Gram’s Stain in comparison to Gram-positive bacteria?

<p>They stain pink, indicating a thinner layer of peptidoglycan and an outer membrane. (D)</p> Signup and view all the answers

Which characteristic is typically associated with the structure of eukaryotic cells?

<p>Organizational complexity with multiple membrane-bound organelles. (B)</p> Signup and view all the answers

What type of cellular structures are common to both prokaryotic and eukaryotic cells?

<p>Plasma membrane. (A), Ribosomes. (C)</p> Signup and view all the answers

Which component is NOT a primary part of the general structure of a cell?

<p>Endoplasmic reticulum. (A)</p> Signup and view all the answers

What structural role does the cytoskeleton serve in eukaryotic cells?

<p>It provides mechanical support and helps maintain cellular structure. (C)</p> Signup and view all the answers

What is the primary structural organization of phospholipids within the plasma membrane?

<p>They are organized into a bilayer with hydrophobic tails facing inward. (C)</p> Signup and view all the answers

How does cholesterol influence the plasma membrane structure?

<p>It induces the formation of lipid rafts that enhance signal transduction. (A), It fits among fatty acid tails, increasing membrane fluidity at low temperatures. (C)</p> Signup and view all the answers

Which statement accurately describes the role of integral proteins in the plasma membrane?

<p>They are permanently attached and span the entire membrane. (A)</p> Signup and view all the answers

What interaction occurs between the polar region of cholesterol and other membrane components?

<p>Cholesterol's polar group forms hydrogen bonds with phospholipid heads. (D)</p> Signup and view all the answers

What is one of the primary functions of carbohydrates attached to the plasma membrane?

<p>They serve as recognition sites for cell signaling. (C)</p> Signup and view all the answers

What characteristic does the phospholipid bilayer exhibit due to its amphipathic nature?

<p>It maintains a stable environment by controlling permeability. (D)</p> Signup and view all the answers

What is the primary barrier function of the plasma membrane?

<p>It separates cytoplasmic materials from outside substances. (A)</p> Signup and view all the answers

In what manner do membrane proteins influence cellular signaling?

<p>They bind to extracellular signals and initiate intracellular responses. (B)</p> Signup and view all the answers

Flashcards

Cell Theory

The concept that cells are the fundamental building blocks of all living organisms. It states that all living things are made up of cells, that all cells arise from pre-existing cells, and that cells are the smallest unit of life that can carry out all the functions necessary for life.

Stem Cells

The ability of cells to differentiate into specialized cell types with specific functions, while maintaining the ability to self-renew. Stem cells play a crucial role in development, growth, and tissue repair.

Prokaryotic Cells

Simple cells lacking a nucleus and other membrane-bound organelles. Their DNA is located in a region called the nucleoid. They are typically smaller than eukaryotic cells and are found in single-celled organisms like bacteria and archaea.

Eukaryotic Cells

Complex cells that have a true nucleus enclosed by a membrane and other membrane-bound organelles. They are found in plants, animals, fungi, and protists.

Signup and view all the flashcards

Plant Cells

Plant cells are distinguished by a rigid cell wall, chloroplasts (for photosynthesis), and a large central vacuole for water storage. They also have a nucleus and other organelles found in animal cells.

Signup and view all the flashcards

Animal Cells

Animal cells lack a cell wall and chloroplasts and have smaller vacuoles. They have a nucleus and other organelles common to plant cells.

Signup and view all the flashcards

Bacteria

Bacteria are prokaryotic cells with unique characteristics such as a peptidoglycan cell wall and a single circular chromosome. They are diverse and can be beneficial or harmful.

Signup and view all the flashcards

Plasma Membrane

The outer boundary of a cell, selectively regulating the passage of molecules in and out. It is a phospholipid bilayer with embedded proteins that control transport. It is vital for maintaining cell homeostasis.

Signup and view all the flashcards

What are flagella?

Short, hair-like structures that can be found on some prokaryotic cells. They are used for cell movement - the rotary motion propels the cell.

Signup and view all the flashcards

What is peptidoglycan?

A thick, mesh-like layer found in the cell wall of gram-positive bacteria. It is composed mainly of peptidoglycan (50-90% of the cell wall) and stains purple.

Signup and view all the flashcards

What is a gram-positive bacteria?

Bacteria with a thick peptidoglycan layer in their cell wall that stains purple.

Signup and view all the flashcards

What is a gram-negative bacteria?

Bacteria with a thin peptidoglycan layer in their cell wall that stains pink.

Signup and view all the flashcards

What is a eukaryotic cell?

Cells that possess a membrane-bound nucleus. They are more complex than prokaryotic cells and compartmentalize functions within organelles and the endomembrane system.

Signup and view all the flashcards

What is cytosol?

The fluid component of the cytoplasm, excluding the organelles.

Signup and view all the flashcards

What is the cytoskeleton?

A structural network found in the cytoplasm of eukaryotic cells. It provides support, helps maintain cellular structure, and facilitates movement.

Signup and view all the flashcards

What is the plasma membrane?

The outermost layer of a cell that regulates the passage of substances in and out of the cell.

Signup and view all the flashcards

Totipotent stem cells

Cells that can form any cell type in the body, including the placenta. They are found in the early embryo.

Signup and view all the flashcards

Pluripotent stem cells

Cells that can differentiate into nearly all cell types in the body, except for the placenta. They are found in the inner cell mass of the blastocyst.

Signup and view all the flashcards

Multipotent stem cells

Cells that can differentiate into a limited number of cell types, but only within a specific germ layer. Found in various tissues throughout the body.

Signup and view all the flashcards

Oligopotent stem cells

Cells that can differentiate into only a few cell types, such as lymphoid or myeloid stem cells. Found in bone marrow and other tissues.

Signup and view all the flashcards

Unipotent stem cells

Cells that can only produce one type of cell, their own, but retain the ability to self-renew. Found in various tissues throughout the body.

Signup and view all the flashcards

Symmetric stem cell division

A type of cell division where a stem cell divides into two identical daughter cells, both of which remain stem cells.

Signup and view all the flashcards

Asymmetric stem cell division

A type of cell division where a stem cell divides into one identical daughter cell and one daughter cell that becomes a progenitor cell.

Signup and view all the flashcards

Progenitor cell

A cell that is committed to a particular cell lineage but has not yet fully differentiated. Found in various tissues throughout the body.

Signup and view all the flashcards

Differentiated cell

A cell that has fully matured and has a specific function. Found in various tissues throughout the body.

Signup and view all the flashcards

Cell differentiation

The process by which a cell changes from an undifferentiated state to a specialized cell type. This process involves changes in gene expression and protein synthesis.

Signup and view all the flashcards

Cholesterol's Role in Membrane Fluidity

Cholesterol acts as a temperature control agent for the plasma membrane: in warm temperatures, it prevents phospholipids from moving too freely; in cold temperatures, it maintains fluidity by stopping phospholipids from packing too tightly.

Signup and view all the flashcards

What are Glycolipids?

Glycolipids are lipids with attached carbohydrate groups. They are found only on the outer layer of the plasma membrane, facing the extracellular fluid. This contributes to the asymmetry of the membrane, meaning the two halves are different.

Signup and view all the flashcards

What are Integral Membrane Proteins?

Integral membrane proteins are embedded within the lipid bilayer. They are amphipathic, meaning they have both hydrophilic and hydrophobic regions. Many are transmembrane proteins, spanning the entire membrane.

Signup and view all the flashcards

What are Transmembrane Proteins?

Transmembrane proteins are integral membrane proteins that extend across the entire lipid bilayer. They play various roles, including forming channels for ion or water transport, transmitting chemical signals, and anchoring protein filaments.

Signup and view all the flashcards

What are Peripheral Membrane Proteins?

Peripheral membrane proteins are loosely attached to the membrane surface, interacting with the polar regions of integral proteins. They are not amphipathic and don't associate with the nonpolar lipid interior.

Signup and view all the flashcards

What are Glycoproteins?

Many membrane proteins are glycoproteins, which are proteins with carbohydrate groups attached. These carbohydrates protrude into the extracellular fluid. They contribute to forming the glycocalyx, a sugary coat on the outer cell surface.

Signup and view all the flashcards

What is the Glycocalyx?

The glycocalyx is a carbohydrate-rich layer that covers the cell surface, composed of the carbohydrate portions of glycolipids and glycoproteins. It plays a vital role in cell recognition, adhesion, and protection.

Signup and view all the flashcards

What is the Plasma Membrane's Role?

The plasma membrane is a selectively permeable barrier that regulates the passage of molecules in and out of the cell. Its structure, composed of phospholipids, cholesterol, and proteins, allows for controlled transport.

Signup and view all the flashcards

Endoplasmic Reticulum (ER)

The network of interconnected membranous sacs and tubules within a cell, serving as a manufacturing and transport system for proteins and lipids.

Signup and view all the flashcards

Golgi Complex

A stack of flattened, membrane-bound sacs (cisternae) that modifies, sorts, and packages proteins and lipids.

Signup and view all the flashcards

Lysosomes

Small, spherical organelles surrounded by a single membrane that contain enzymes for digestion of cellular waste and foreign materials.

Signup and view all the flashcards

Peroxisomes

Organelles enclosed by a single membrane that contain enzymes for detoxification of various molecules, particularly lipids, alcohol, and toxic substances.

Signup and view all the flashcards

Proteasomes

Barrel-shaped structures found in the cytoplasm of eukaryotic cells that contain proteases (protein-digesting enzymes).

Signup and view all the flashcards

Cytoskeleton

A network of protein filaments that provides structural support, helps with cell movement, and facilitates transport within the cell.

Signup and view all the flashcards

Cytosol

A fluid-filled region within a cell that is composed of water, dissolved ions, and macromolecules, excluding organelles.

Signup and view all the flashcards

What is a centrosome?

A pair of centrioles arranged perpendicularly to each other. Each centriole has 9 triplets of microtubules. Surrounded by pericentriolar material, which helps grow the mitotic spindle.

Signup and view all the flashcards

What are cilia and flagella?

Slender, whip-like structures extending from the cell surface. Composed of microtubules arranged in a 9+2 pattern. Used for cell movement.

Signup and view all the flashcards

What are ribosomes?

Small, round organelles composed of rRNA and protein. Sites of protein synthesis.

Signup and view all the flashcards

What is the endoplasmic reticulum (ER)?

A network of interconnected membranes that extends throughout the cytoplasm. It includes both rough ER and smooth ER.

Signup and view all the flashcards

What is rough ER?

ER studded with ribosomes. Its main function is protein synthesis and modification.

Signup and view all the flashcards

What is smooth ER?

ER lacking ribosomes. It plays a role in lipid synthesis, detoxification, and storage of calcium.

Signup and view all the flashcards

What is a flagellum?

A long tail-like structure found on sperm cells. Used for propelling the sperm during fertilization.

Signup and view all the flashcards

What are cilia?

Hair-like structures found in groups. They are commonly found in the respiratory system to move mucus.

Signup and view all the flashcards

Extra-embryonic tissues

Cells that develop outside the embryo but are crucial for its survival and development. They include the placenta and umbilical cord.

Signup and view all the flashcards

Stem cell potency

The ability of a stem cell to differentiate into different cell types.

Signup and view all the flashcards

Zygote

The first cell of a new organism, formed by the union of a sperm and egg.

Signup and view all the flashcards

Germ layers

The three primary germ layers that give rise to all the body's tissues and organs. They are the ectoderm, endoderm, and mesoderm.

Signup and view all the flashcards

What are gram-positive bacteria?

Prokaryotic cells that have a thick peptidoglycan layer in their cell wall that will stain purple with Gram's stain.

Signup and view all the flashcards

What are gram-negative bacteria?

Prokaryotic cells that have a thin peptidoglycan layer in their cell wall that will stain pink with Gram's stain.

Signup and view all the flashcards

What are eukaryotic cells?

A membrane-bound nucleus is present, the cell compartmentalizes many functions within organelles and the endomembrane system, and the cell possesses a cytoskeleton for support and to maintain cellular structure. These cells make up plants, animals, fungi, and protists.

Signup and view all the flashcards

What are prokaryotic cells?

Lacking a nucleus and other membrane-bound organelles. Their DNA is located in a region called the nucleoid. They are typically smaller than eukaryotic cells and are found in single-celled organisms like bacteria and archaea.

Signup and view all the flashcards

What is the Golgi complex?

A stack of flattened membranous sacs involved in modifying, sorting, and packaging proteins and lipids into vesicles for transport. It can be viewed as the cell's 'post office'.

Signup and view all the flashcards

How does cholesterol affect membrane fluidity?

Cholesterol helps maintain membrane fluidity by counteracting the effects of temperature. In warm temperatures, cholesterol restricts phospholipid movement, preventing the membrane from becoming too fluid. In cold temperatures, cholesterol prevents tight packing of phospholipids to maintain fluidity.

Signup and view all the flashcards

What is the function of the plasma membrane?

The plasma membrane is a selectively permeable barrier that regulates the passage of molecules in and out of the cell, essential for maintaining homeostasis.

Signup and view all the flashcards

What are phospholipids and how are they arranged in the plasma membrane?

Phospholipids are amphipathic molecules, meaning they have both hydrophilic (water-loving) and hydrophobic (water-fearing) regions. They form a bilayer with the hydrophobic tails facing inwards and the hydrophilic heads facing outwards, creating a barrier between the inside and outside of the cell.

Signup and view all the flashcards

What is the role of cholesterol in the plasma membrane?

Cholesterol is a lipid molecule that is embedded within the phospholipid bilayer of the plasma membrane. It helps to regulate the fluidity of the membrane, preventing it from becoming too rigid or too fluid.

Signup and view all the flashcards

What are integral membrane proteins and what are their functions?

Integral membrane proteins are embedded within the phospholipid bilayer. They are amphipathic, meaning they have both hydrophilic and hydrophobic regions. Many are transmembrane proteins, spanning the entire membrane. They play vital roles in transport, signaling, and anchoring.

Signup and view all the flashcards

What are peripheral membrane proteins and where are they located?

Peripheral membrane proteins are loosely attached to the membrane surface, interacting with the polar regions of integral proteins. They are not amphipathic and don't associate with the nonpolar lipid interior. They are involved in various functions on the cell surface.

Signup and view all the flashcards

What is the role of carbohydrate groups attached to the plasma membrane?

Attached carbohydrates (glycolipids and glycoproteins) are found on the outer surface of the plasma membrane. They play a vital role in cell recognition, adhesion, and signaling.

Signup and view all the flashcards

Mitochondria

Sausage-shaped organelles with folded membranes called cristae and a fluid matrix containing enzymes. They have their own DNA and ribosomes, allowing them to make their own proteins.

Signup and view all the flashcards

Mitochondrial function

The primary site of ATP production through cellular respiration, utilizing oxygen and producing carbon dioxide.

Signup and view all the flashcards

Nucleus

The control center of the cell containing DNA, the genetic material, organized into chromosomes.

Signup and view all the flashcards

Nucleolus

A densely staining region within the nucleus that produces ribosomes, crucial for protein synthesis.

Signup and view all the flashcards

Chromatin

The thin network of threads formed by DNA and proteins within the nucleus, containing the genetic information for the cell.

Signup and view all the flashcards

What is the nucleus?

A round or oval structure enclosed by a membrane with pores, containing the cell's genetic material.

Signup and view all the flashcards

Protein synthesis directed by DNA

The process by which DNA directs the synthesis of proteins, both within the cell and in newly formed cells during cell reproduction.

Signup and view all the flashcards

What is the nucleolus?

A membrane enclosed structure within the nucleus that produces ribosomes, which are essential for protein synthesis.

Signup and view all the flashcards

Study Notes

MPharm Programme - Cell Science - Introduction to Cellular Structure 1 & 2

  • The course is PHA115, Cellular Structure 1 & 2, taught by Dr. Praveen Bhugra.
  • The learning objectives include understanding and explaining in detail cell theory, stem cell theory, differences between prokaryotic and eukaryotic cells, differentiation between plant, animal cells and bacteria, and structure and function of plasma membrane, cytoplasm (cytosol and organelles), and the nucleus.

Cells Theory

  • Cells are the building blocks of all plants and animals.
  • All cells come from the division of pre-existing cells.
  • Cells are the smallest units that perform all vital physiological functions.
  • Each cell maintains homeostasis at the cellular level.

Cells in the human body

  • The human body is composed of cells.
  • An estimated 3.72 x 10¹³ cells exist in the human body.
  • A variety of cell types exist within the human body (approximately 200 types).
  • Cells contain organelles, which have diverse functions.

Diversity of Human Cells

  • Adult humans contain more than 200 different kinds of cells.
  • These include nerve, muscle, skin, blood, bone, and cartilage cells.
  • Extra-embryonic tissues like the placenta and umbilical cord are essential for embryonic development.
  • Specific types of cells have specialized structures and functions.

Stem cells

  • Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (mitosis) to create more stem cells.
  • Two primary types of stem cells in mammals are embryonic stem cells and adult stem cells.
  • Embryonic stem cells are derived from the inner cell mass of blastocysts.
  • Adult stem cells are found in various tissues and function in tissue repair.
  • In a developing embryo, stem cells can differentiate into three germ layers (ectoderm, mesoderm, and endoderm).

Stem cells potency

  • Totipotent stem cells can differentiate into all types of cell types (including embryonic and extra-embryonic).
  • Pluripotent stem cells can differentiate into nearly all cells derived from the three germ layers.
  • Multipotent stem cells differentiate into a number of closely related cell types.
  • Oligopotent stem cells differentiate into just a few closely related cell types.
  • Unipotent stem cells differentiate into just one cell type and have self-renewal abilities.

Stem cell division and differentiation

  • Stem cells divide and differentiate to produce progenitor cells and differentiated cells.
  • Stem cell division and differentiation can be symmetric or asymmetric and lead to progenitor cell division, followed by terminal differentiation.

Potential uses of stem cells

  • Stem cells have potential applications in treating various diseases and conditions (stroke, traumatic brain injury, learning defects, and others), though their therapeutic uses are complex and developing.

Stem cells potency & source developmental

  • Totipotent embryonic stem cells are the most versatile.
  • Pluripotent embryonic stem cells and induced pluripotent stem cells can generate multiple cell types.
  • Multipotent stem cells can generate a range of cells within a family of related cells.

Hierarchy of haemopoietin differentiation

  • Stem cells give rise to progenitor cells and mature cells (blood cells).
  • Blood cells are categorized into different lineages, with specific progenitor cells leading to distinct blood cell types.
  • This process is complex, involving multiple steps and lineage-committed precursors.

Characteristics of all cell types

  • All cell types have a surrounding membrane, protoplasm, organelles, and a control center with DNA.
  • This leads to prokaryotic and eukaryotic cell categorization.

Characteristics of prokaryotic cells (Bacteria)

  • Lack a nucleus and membrane-bound organelles.
  • Simplest cell type with a single, circular chromosome.
  • The nucleoid region contains DNA.
  • Surrounded by a cell membrane and cell wall (peptidoglycan).
  • Contain ribosomes for protein synthesis.
  • Can be Gram-positive or Gram-negative based on cell wall structure.

Characteristics of eukaryotic cells

  • Possess a membrane-bound nucleus.
  • More complex than prokaryotic cells, with compartmentalization of functions in organelles.
  • Possess a cytoskeleton for support and to maintain cellular structure.
  • Include fungi, protozoa, plants, and animals.

An animal cell and A plant cell.

  • Both animal and plant cells have a nucleus, cytoplasm, and cell membrane.
  • Plant cells have a cell wall, vacuoles, and chloroplasts.
  • Animal cells may contain different specialized organelles.

Plant cell

  • Plant cells have specific organelles, such as chloroplasts, central vacuole, and a cell wall, that are absent in animal cells.

Animal Cell

  • Animal cells are characterized by diverse organelles (e.g., lysosomes, centrioles) that may not be present in plant cells.

Cell Structure

  • The three main parts of a cell are the plasma membrane, cytoplasm (cytosol and organelles), and the nucleus.

Generalized View of Cell Structure

  • The cell has components that are part of its structure and their functions, including various organelles, and the cytoskeleton.

Plasma membrane

  • Main structural element in cells, made of a phospholipid bilayer, cholesterol, and proteins.
  • Proteins associated with carbohydrates are glycolipids and glycoproteins.
  • The functions of membranes include a barrier between inside and outside of the cell, regulation of transport of materials, and transmitting signals between different areas within and outside the cell.
  • Membranes include types of junctions (desmosomes, tight junctions, and gap junctions).

Plasma membrane (Phospholipids)

  • Phospholipids are amphipathic molecules that form a bilayer in cell membranes.

Plasma membrane (Cholesterol)

  • Cholesterol plays a key role in regulating membrane fluidity at different temperatures.

Plasma membrane (Glycolipids)

  • Glycolipids are membrane lipids with carbohydrate groups that face the extracellular fluid.

Plasma Membrane (Protein)

  • Integral membrane proteins are tightly associated with the membrane and span the lipid bilayer.
  • Peripheral membrane proteins are loosely associated with the membrane.

Plasma Membrane (Junctions)

  • Various junction types connect cells (e.g., desmosomes, tight junctions, and gap junctions).
  • Integrins are transmembrane proteins that link the membrane to the extracellular matrix.
  • Specific proteins associated with junctions help in cell-to-cell interactions.

Desmosomes

  • Structures that anchor cells together in tissues that undergo stretching.

Tight junctions

  • Link cells tightly, creating an impermeable seal that prevents the leakage of materials between cells.

Gap junctions

  • Protein channels that connect the cytosols of adjacent cells, allowing small molecules, ions, and signaling molecules to pass between cells.

Functions of Cell Membranes

  • Regulate passage of substances in and out of cells.
  • Detect chemical messengers.
  • Link adjacent cells.
  • Anchor cells to the extracellular matrix.

Cytoplasm (Cytosol)

  • The fluid component of the cytoplasm.
  • Consists mostly of water plus dissolved substances, including ions, nutrients, and waste products.

Cytoplasm (Cell Organelles)

  • Contains various organelles such as cytoskeleton, flagella, cilia, centrioles, endoplasmic reticulum, Golgi apparatus, mitochondria, nucleus, nucleolus, and nuclear envelope, vesicles, lysosomes, peroxisomes, proteasomes.

Cell organelles (Cytoskeleton)

  • Maintains the shape of the cell, positions organelles, and changes cell shape.
  • Includes microfilaments, intermediate filaments, and microtubules, which are involved in various cellular processes.

Cell organelles (Centrosome)

  • An organizing center for microtubules, playing a key role in cell division.

Cell organelles (Cilia and Flagella)

  • Specialized for motion.
  • Flagella provide movement for sperm cells; cilia allow for movement of fluids and mucus.

Cell organelles (Ribosomes)

  • Sites of protein synthesis.
  • Found free in the cytosol or attached to the endoplasmic reticulum.

Cell organelles (Endoplasmic Reticulum (E.R.))

  • Network of folded membranes involved in protein synthesis, lipid synthesis, and intracellular transport.
  • The ER has rough and smooth regions, each with specific functions.

Cell organelles (Golgi Complex)

  • Modifies proteins and lipids and packages them for secretion or transport to other organelles.

Cell organelles (Lysosomes)

  • Contain digestive enzymes for breaking down cellular waste.

Cell organelles (Peroxisomes)

  • Contain enzymes for detoxification reactions.

Cell organelles (Proteasomes)

  • Breakdown of unneeded or damaged proteins.

Cell organelles (Mitochondria)

  • The major site of ATP production in cells.
  • Contain DNA and ribosomes.
  • High concentration in cells with high energy demands (muscle, liver, kidney).
  • Contain specialized structures like cristae.
  • Involved in cellular respiration.

Nucleus

  • The control center of the cell, containing DNA and nucleolus, responsible for regulating protein synthesis, and cell division.
  • Contains chromatin, a complex of DNA and associated proteins.
  • Involved in gene regulation and transcription.

Comparison of Bacterial, Animal and Plant cells

  • A table summarizing the main structural differences across bacterial, animal, and plant cells, indicating the presence or absence of various structures (cell wall, plasma membrane, flagella, DNA, etc.).

Further Reading

  • List of textbooks for further study.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Use Quizgecko on...
Browser
Browser