Podcast
Questions and Answers
What defines a compound?
What defines a compound?
- A substance consisting of only one type of atom.
- A substance made of two or more different elements chemically bonded. (correct)
- The basic unit of an element, consisting of protons, neutrons, and electrons.
- A group of atoms bonded together, representing the smallest unit of a substance.
Which type of bond is characterized by the transfer of electrons?
Which type of bond is characterized by the transfer of electrons?
- Covalent bond
- Hydrogen bond
- Hydrophobic interaction
- Ionic bond (correct)
What does electronegativity measure?
What does electronegativity measure?
- An atom's ability to attract electrons in a bond. (correct)
- The charge of an ion.
- The size of an atom compared to others.
- The number of protons in an atom.
Which statement best describes polar molecules?
Which statement best describes polar molecules?
What is the role of a solvent in a solution?
What is the role of a solvent in a solution?
What additional component is found in plant cells but not in animal cells?
What additional component is found in plant cells but not in animal cells?
Which structure is primarily responsible for ATP production in cells?
Which structure is primarily responsible for ATP production in cells?
What is the function of ribosomes in the cell?
What is the function of ribosomes in the cell?
What role does the Golgi apparatus play in cellular function?
What role does the Golgi apparatus play in cellular function?
Which of the following correctly describes the structure of the cell membrane?
Which of the following correctly describes the structure of the cell membrane?
Which of the following is not part of the endomembrane system?
Which of the following is not part of the endomembrane system?
What is the primary function of lysosomes?
What is the primary function of lysosomes?
What structural feature distinguishes a phospholipid?
What structural feature distinguishes a phospholipid?
Which molecule serves as a primary energy storage component in the body?
Which molecule serves as a primary energy storage component in the body?
Which component of the cytoskeleton is involved in cellular movement?
Which component of the cytoskeleton is involved in cellular movement?
What type of reaction involves the formation of a larger molecule by releasing a water molecule?
What type of reaction involves the formation of a larger molecule by releasing a water molecule?
What is the primary structural component of bacterial cells?
What is the primary structural component of bacterial cells?
Which functional group is characterized as acidic due to its ability to donate protons?
Which functional group is characterized as acidic due to its ability to donate protons?
During protein processing, what happens after the rough ER synthesizes proteins?
During protein processing, what happens after the rough ER synthesizes proteins?
How do proteins primarily differ from one another?
How do proteins primarily differ from one another?
Which structure provides genetic material storage in the cell?
Which structure provides genetic material storage in the cell?
What type of cell structure is shared by all cells, regardless of being prokaryotic or eukaryotic?
What type of cell structure is shared by all cells, regardless of being prokaryotic or eukaryotic?
Which component of a plant cell is primarily responsible for maintaining turgor pressure?
Which component of a plant cell is primarily responsible for maintaining turgor pressure?
Which molecule is essential for synthesizing proteins based on genetic information?
Which molecule is essential for synthesizing proteins based on genetic information?
What distinguishes prokaryotic cells from eukaryotic cells?
What distinguishes prokaryotic cells from eukaryotic cells?
What is not a function of the plasma membrane?
What is not a function of the plasma membrane?
Cholesterol contributes to cell membrane stability by:
Cholesterol contributes to cell membrane stability by:
Which carbohydrate serves primarily as a structural component in plants?
Which carbohydrate serves primarily as a structural component in plants?
What distinguishes hydrophobic amino acids from hydrophilic ones?
What distinguishes hydrophobic amino acids from hydrophilic ones?
Which of the following organisms is characterized as being prokaryotic?
Which of the following organisms is characterized as being prokaryotic?
The main role of dehydration synthesis in carbohydrate formation is to:
The main role of dehydration synthesis in carbohydrate formation is to:
What is a characteristic of isomers?
What is a characteristic of isomers?
What is the primary role of phospholipids in the cell membrane?
What is the primary role of phospholipids in the cell membrane?
What function does cholesterol perform in the cell membrane?
What function does cholesterol perform in the cell membrane?
Which type of protein is responsible for allowing the passage of small hydrophilic molecules through the lipid bilayer?
Which type of protein is responsible for allowing the passage of small hydrophilic molecules through the lipid bilayer?
What characterizes passive transport?
What characterizes passive transport?
Active transport involves which of the following?
Active transport involves which of the following?
Facilitated diffusion requires which components?
Facilitated diffusion requires which components?
What are sodium-potassium pumps primarily responsible for?
What are sodium-potassium pumps primarily responsible for?
In glycolysis, which molecule is formed from glucose?
In glycolysis, which molecule is formed from glucose?
What is produced during the energy investment phase of glycolysis?
What is produced during the energy investment phase of glycolysis?
Where does oxidative phosphorylation occur in the cell?
Where does oxidative phosphorylation occur in the cell?
What defines selective permeability in a membrane?
What defines selective permeability in a membrane?
What is the major output of glycolysis?
What is the major output of glycolysis?
What is a function of recognition proteins?
What is a function of recognition proteins?
Which process describes phagocytosis?
Which process describes phagocytosis?
Where does pyruvate oxidation occur in prokaryotic cells?
Where does pyruvate oxidation occur in prokaryotic cells?
Which molecule is produced during pyruvate oxidation?
Which molecule is produced during pyruvate oxidation?
What is the final electron acceptor in the electron transport chain?
What is the final electron acceptor in the electron transport chain?
Which process is involved in the production of ATP during oxidative phosphorylation?
Which process is involved in the production of ATP during oxidative phosphorylation?
What does the citric acid cycle primarily produce per acetyl-CoA molecule?
What does the citric acid cycle primarily produce per acetyl-CoA molecule?
What is the primary function of the Calvin Cycle?
What is the primary function of the Calvin Cycle?
Which enzyme catalyzes the first step of the Calvin Cycle?
Which enzyme catalyzes the first step of the Calvin Cycle?
What is the purpose of the light reactions in photosynthesis?
What is the purpose of the light reactions in photosynthesis?
How does water contribute to the light reactions of photosynthesis?
How does water contribute to the light reactions of photosynthesis?
In which part of the chloroplast does the Calvin Cycle occur?
In which part of the chloroplast does the Calvin Cycle occur?
Which of the following best describes an enzyme?
Which of the following best describes an enzyme?
Where does the citric acid cycle take place in eukaryotic cells?
Where does the citric acid cycle take place in eukaryotic cells?
Which reactants are needed for ATP production by ATP synthase?
Which reactants are needed for ATP production by ATP synthase?
What is the role of an inhibitor in enzyme activity?
What is the role of an inhibitor in enzyme activity?
What is the primary function of NADH in cellular respiration?
What is the primary function of NADH in cellular respiration?
Which of the following correctly represents a competitive inhibitor's function?
Which of the following correctly represents a competitive inhibitor's function?
What overall equation summarizes the process of photosynthesis?
What overall equation summarizes the process of photosynthesis?
How do temperature fluctuations affect enzyme activity?
How do temperature fluctuations affect enzyme activity?
Which of these statements about chemiosmosis is correct?
Which of these statements about chemiosmosis is correct?
Which process do photosynthesis and cellular respiration have in common?
Which process do photosynthesis and cellular respiration have in common?
What is the main purpose of the Calvin Cycle?
What is the main purpose of the Calvin Cycle?
What is the main product generated by the Calvin Cycle?
What is the main product generated by the Calvin Cycle?
What does signal transduction involve?
What does signal transduction involve?
Which term describes the small molecules that relay signals within a cell?
Which term describes the small molecules that relay signals within a cell?
Which type of cell communication involves a ligand binding to a receptor on the same cell?
Which type of cell communication involves a ligand binding to a receptor on the same cell?
Why is amplification important in cell signaling?
Why is amplification important in cell signaling?
What occurs during the conformational change of a receptor?
What occurs during the conformational change of a receptor?
What does the law of independent assortment state regarding the arrangement of chromosomes during meiosis?
What does the law of independent assortment state regarding the arrangement of chromosomes during meiosis?
How does the law of segregation specifically affect the alleles of a single gene during meiosis?
How does the law of segregation specifically affect the alleles of a single gene during meiosis?
What is the primary consequence of nondisjunction during meiosis?
What is the primary consequence of nondisjunction during meiosis?
What term refers to the location of a gene on a chromosome?
What term refers to the location of a gene on a chromosome?
Which of the following describes a consequence of chromosomal rearrangements for human health?
Which of the following describes a consequence of chromosomal rearrangements for human health?
How do phenotypes relate to genotypes at the molecular level?
How do phenotypes relate to genotypes at the molecular level?
What is the role of the centromere in chromosome structure?
What is the role of the centromere in chromosome structure?
What does aneuploidy refer to in terms of chromosomal abnormalities?
What does aneuploidy refer to in terms of chromosomal abnormalities?
What is the primary function of the ovaries in the female reproductive system?
What is the primary function of the ovaries in the female reproductive system?
What role does the oviduct play in the reproductive system?
What role does the oviduct play in the reproductive system?
What triggers ovulation in the female reproductive cycle?
What triggers ovulation in the female reproductive cycle?
Which hormone is primarily responsible for maintaining the endometrium during pregnancy?
Which hormone is primarily responsible for maintaining the endometrium during pregnancy?
What is the outcome if fertilization does not occur?
What is the outcome if fertilization does not occur?
What occurs during the acrosome reaction of fertilization?
What occurs during the acrosome reaction of fertilization?
What happens during the cleavage stage of development?
What happens during the cleavage stage of development?
Which of the following hormones is primarily produced in the testes?
Which of the following hormones is primarily produced in the testes?
What is the main purpose of hormonal birth control?
What is the main purpose of hormonal birth control?
What is the primary function of the placenta during pregnancy?
What is the primary function of the placenta during pregnancy?
Which hormone signals the corpus luteum to continue producing progesterone after implantation?
Which hormone signals the corpus luteum to continue producing progesterone after implantation?
What is a key difference between mitosis and meiosis?
What is a key difference between mitosis and meiosis?
At what point does an embryo transition into a fetus?
At what point does an embryo transition into a fetus?
Where does the majority of estrogen production occur in females?
Where does the majority of estrogen production occur in females?
What occurs to the endometrium if implantation is successful?
What occurs to the endometrium if implantation is successful?
What is one of the crucial roles of progesterone during the first trimester of pregnancy?
What is one of the crucial roles of progesterone during the first trimester of pregnancy?
What process is described when the cervix widens to prepare for delivery?
What process is described when the cervix widens to prepare for delivery?
What initiates the process of spermatogenesis?
What initiates the process of spermatogenesis?
How does apoptosis contribute to human development?
How does apoptosis contribute to human development?
What may result from low levels of both estrogen and progesterone?
What may result from low levels of both estrogen and progesterone?
Which statement correctly describes the interaction between genes in epistasis?
Which statement correctly describes the interaction between genes in epistasis?
What defines a dominant allele in genetics?
What defines a dominant allele in genetics?
How do hormones within the embryo control its development?
How do hormones within the embryo control its development?
What does polygenic inheritance refer to?
What does polygenic inheritance refer to?
What is the main characteristic of a homozygous organism?
What is the main characteristic of a homozygous organism?
What does the blending hypothesis of inheritance propose?
What does the blending hypothesis of inheritance propose?
Which genetic term describes variants of genes that result in different traits?
Which genetic term describes variants of genes that result in different traits?
What occurs when a hydrophilic ligand binds to its receptor?
What occurs when a hydrophilic ligand binds to its receptor?
How do lipid-soluble ligands generally differ from hydrophilic ligands in terms of receptor location?
How do lipid-soluble ligands generally differ from hydrophilic ligands in terms of receptor location?
What is the primary role of a G-protein when activated by a ligand-receptor complex?
What is the primary role of a G-protein when activated by a ligand-receptor complex?
What is the consequence of continuously active signaling pathways in cells?
What is the consequence of continuously active signaling pathways in cells?
During cellular signaling, what role do second messengers play?
During cellular signaling, what role do second messengers play?
What is a characteristic structural feature of hydrophobic ligands?
What is a characteristic structural feature of hydrophobic ligands?
Which type of hormone is primarily responsible for regulating sleep-wake cycles?
Which type of hormone is primarily responsible for regulating sleep-wake cycles?
What happens during spermatogenesis after the formation of secondary spermatocytes?
What happens during spermatogenesis after the formation of secondary spermatocytes?
What is the role of the pituitary gland within the endocrine system?
What is the role of the pituitary gland within the endocrine system?
What initiates a phosphorylation cascade during signal transduction?
What initiates a phosphorylation cascade during signal transduction?
What is the main feature of oogenesis as it occurs in females?
What is the main feature of oogenesis as it occurs in females?
What triggers the resumption of meiosis in primary oocytes at puberty?
What triggers the resumption of meiosis in primary oocytes at puberty?
How is signal termination achieved in cell signaling pathways?
How is signal termination achieved in cell signaling pathways?
Which of the following is NOT a possible cellular response to signaling pathways?
Which of the following is NOT a possible cellular response to signaling pathways?
What is the main function of the thymus gland in childhood?
What is the main function of the thymus gland in childhood?
Flashcards
Element
Element
A substance composed of only one type of atom.
Compound
Compound
Two or more different elements chemically combined.
Electronegativity
Electronegativity
A measure of an atom's ability to attract electrons in a chemical bond.
Covalent bond
Covalent bond
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Ionic bond
Ionic bond
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3D Structure of Molecules
3D Structure of Molecules
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Isomers
Isomers
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Membrane Transport Protein
Membrane Transport Protein
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Hydroxyl Group
Hydroxyl Group
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Carboxyl Group
Carboxyl Group
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Phosphate Group
Phosphate Group
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Dehydration Reaction
Dehydration Reaction
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Hydrolysis
Hydrolysis
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Monosaccharide
Monosaccharide
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Polysaccharide
Polysaccharide
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Fats
Fats
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Phospholipid
Phospholipid
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Cholesterol
Cholesterol
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Amino Acids
Amino Acids
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Polypeptides
Polypeptides
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Nuclear Envelope
Nuclear Envelope
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Endoplasmic Reticulum (ER)
Endoplasmic Reticulum (ER)
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Cytoplasm
Cytoplasm
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Ribosomes
Ribosomes
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Golgi Apparatus
Golgi Apparatus
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Lysosomes
Lysosomes
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Central Vacuole (plant cells only)
Central Vacuole (plant cells only)
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Mitochondria
Mitochondria
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Chloroplasts
Chloroplasts
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Cell Wall
Cell Wall
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Extracellular Matrix
Extracellular Matrix
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Cytoskeleton
Cytoskeleton
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Intercellular Junctions
Intercellular Junctions
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Endomembrane System
Endomembrane System
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Protein Production and Processing
Protein Production and Processing
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Phospholipid Bilayer Function
Phospholipid Bilayer Function
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Protein Functions in the Membrane
Protein Functions in the Membrane
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Cholesterol Function
Cholesterol Function
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Selective permeability
Selective permeability
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Passive Transport
Passive Transport
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Active Transport
Active Transport
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Facilitated Diffusion
Facilitated Diffusion
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Direct Diffusion
Direct Diffusion
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Diffusion
Diffusion
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Glycolysis
Glycolysis
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Citric Acid Cycle
Citric Acid Cycle
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Oxidative Phosphorylation
Oxidative Phosphorylation
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Endocytosis
Endocytosis
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Exocytosis
Exocytosis
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Phagocytosis
Phagocytosis
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Pinocytosis
Pinocytosis
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Cell Communication
Cell Communication
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Ligand
Ligand
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Receptor
Receptor
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Conformational Change
Conformational Change
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Signal Transduction
Signal Transduction
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Signal Amplification
Signal Amplification
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Signaling Cascade
Signaling Cascade
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Phosphorylation Cascade
Phosphorylation Cascade
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Kinase
Kinase
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Second Messenger
Second Messenger
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Cellular Respiration
Cellular Respiration
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Photosynthesis
Photosynthesis
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Photosynthesis
Photosynthesis
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Calvin Cycle
Calvin Cycle
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Enzyme
Enzyme
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Pyruvate Oxidation
Pyruvate Oxidation
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Acetyl-CoA
Acetyl-CoA
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Electron Transport Chain (ETC)
Electron Transport Chain (ETC)
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Chemiosmosis
Chemiosmosis
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ATP synthase
ATP synthase
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Light Reactions
Light Reactions
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Photosystem
Photosystem
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Electron Transport Chain (ETC) in photosynthesis
Electron Transport Chain (ETC) in photosynthesis
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NADP+
NADP+
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Photolysis
Photolysis
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Energy from Glucose
Energy from Glucose
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Chemiosmosis in Photosynthesis
Chemiosmosis in Photosynthesis
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Cellular Response
Cellular Response
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Termination of the Signal
Termination of the Signal
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Lipid-soluble (hydrophobic) ligands
Lipid-soluble (hydrophobic) ligands
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Water-soluble (hydrophilic) ligands
Water-soluble (hydrophilic) ligands
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Intracellular receptors
Intracellular receptors
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Cell surface receptors
Cell surface receptors
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Insulin
Insulin
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Glucagon
Glucagon
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Spermatogenesis
Spermatogenesis
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Law of Independent Assortment
Law of Independent Assortment
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Law of Segregation
Law of Segregation
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Linked Genes
Linked Genes
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What is a centromere?
What is a centromere?
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What are the p and q arms of a chromosome?
What are the p and q arms of a chromosome?
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What is a Locus?
What is a Locus?
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What is aneuploidy?
What is aneuploidy?
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Explain nondisjunction.
Explain nondisjunction.
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Ovulation
Ovulation
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Fertilization
Fertilization
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Ovary
Ovary
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Oviduct (Fallopian tube)
Oviduct (Fallopian tube)
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Uterus
Uterus
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Endometrium
Endometrium
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Cervix
Cervix
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Vagina
Vagina
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Testis
Testis
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Scrotum
Scrotum
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Epididymis
Epididymis
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Vas Deferens
Vas Deferens
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Seminal Vesicle
Seminal Vesicle
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Prostate Gland
Prostate Gland
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Bulbourethral Gland
Bulbourethral Gland
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Implantation
Implantation
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Placenta
Placenta
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Human β-chorionic Gonadotropin (β-HCG)
Human β-chorionic Gonadotropin (β-HCG)
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Progesterone
Progesterone
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Embryo
Embryo
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Apoptosis
Apoptosis
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Parturition
Parturition
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Oxytocin
Oxytocin
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Prostaglandins
Prostaglandins
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Expulsion
Expulsion
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Afterbirth
Afterbirth
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Gene
Gene
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Allele
Allele
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Study Notes
Unit 1: Biological Macromolecules
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Basic Chemistry Concepts: Element, compound, molecule, atom, electronegativity, nonpolar, polar, covalent bonds, ionic bonds, hydrogen bonds, hydrophobic interactions, cation, anion, hydrophilic, hydrophobic, pH, solvent, solute, solution. These terms describe the fundamental building blocks and interactions of matter, critical for understanding biological molecules.
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Importance of 3D Structure: Molecular structure (e.g., tetrahedral) affects properties and function. Isomers have the same formula but different arrangements, leading to different properties. An example given is protein structure affecting its function, like a transmembrane domain that forms a channel or binding site for molecules across a membrane.
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Functional Groups: Hydroxyl (-OH), carboxyl (-COOH), amino (-NH₂), phosphate (-PO₄). Each group has specific properties (polarity, acidity) influencing the behavior of larger molecules containing them.
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Dehydration and Hydrolysis: Dehydration reactions build larger molecules by removing water; hydrolysis breaks down larger molecules by adding water.
Carbohydrates
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Monomers, Dimers, Polymers: Monosaccharides (e.g., glucose) are the monomers; polysaccharides are polymers. Examples of polymers include starch and glycogen (function as storage molecules), and cellulose (structure).
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Structural and Functional Differences: Starch/glycogen have a twisted structure for compact glucose storage; cellulose has a straight structure enabling hydrogen bonding between strands. They differ in their functions and forms; starch/glycogen are storage molecules, cellulose is a structural component.
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Carbohydrate Functions: Energy storage (storing glucose, forming starch and glycogen), and structural support (cellulose). Different sugars form diverse molecular compounds, e.g., glucose becomes maltose, sucrose, and lactose.
Lipids
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Categories: Fats, proteins, steroids, and phospholipids. Focus on fats and phospholipids for this unit.
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Fat Function: Energy storage (more than carbohydrates can) and insulation/cushioning.
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Phospholipid Structure: Hydrophilic head, hydrophobic tail. Diagram needed, showing these components.
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Phospholipid Function: Crucial for creating a hydrophobic barrier that divides aqueous solutions, e.g., cell membranes.
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Cholesterol Function: Maintaining membrane stability and fluidity, acting as a “buffer,” by preventing overly tight packing/too much movement of phospholipids at different temperatures.
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Steroid Hormone Production: Cholesterol is a precursor for steroidal hormones.
Proteins
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4 Protein Functions: Defense, transport, signaling, receptor action, structure, and contraction.
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Building Blocks: Monomers are amino acids; polymers are polypeptides.
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Amino Acid Differences: R-groups (20 unique) create differences in function and properties, causing differences among the 20 types of amino acids.
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Amino Acid Groups: Nonpolar (hydrophobic), polar (hydrophilic), and charged (hydrophilic).
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Structure-Function Relationship: Protein structure (primary to quaternary) directly dictates the protein's function.
Nucleic Acids
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Monomer and Polymer: Monomers are nucleotides; polymers are polynucleotides. Examples are DNA and RNA.
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DNA & RNA Functions: DNA stores genetic information and instructions. RNA uses this information to produce proteins. (DNA → RNA → protein)
Cell Structures and Membrane Transport
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Cell Theory: All living things are made of one or more cells; all cells come from existing cells.
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Cell Size Limitations: Cells require a large surface area to volume ratio to effectively exchange materials across the plasma membrane.
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Universal Cell Features: Plasma membrane, cytoplasm, ribosomes, and genetic material (usually DNA).
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Prokaryote/Eukaryote Differences: Prokaryotic cells (smaller, less complex, single chromosome) vs eukaryotic cells (larger, complex, multiple chromosomes).
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Plant/Animal Cell Differences: Plant cells have cell walls (cellulose), chloroplasts, and a central vacuole; animal cells do not.
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Endomembrane System: Includes nuclear envelope, ER, Golgi apparatus, plasma membrane, lysosomes (animals), and central vacuole (plants). Describes the production, processing, and targeting of proteins within the cell.
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Cell Membrane Structure: Phospholipid bilayer (hydrophilic heads, hydrophobic tails), cholesterol, membrane proteins.
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Fluid Mosaic Model: The membrane is a fluid structure where components can move laterally.
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Membrane Components: Phospholipid bilayer, proteins (enzymes, receptors, attachment, transport, junction, recognition), and cholesterol.
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Selective Permeability: Membranes are selectively permeable, allowing specific molecules to pass through, regulated by the properties of the membrane components (e.g., phospholipids, proteins).
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Membrane Transport: Passive (diffusion, facilitated) vs Active (sodium potassium pump), including both facilitated and direct diffusion.
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Endocytosis and Exocytosis: Internalization and secretion of membrane components. Diagram needed, showing phagocytosis, pinocytosis, and exocytosis.
Energy Processing & Enzymes
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Cellular Respiration: Glycolysis, citric acid cycle, and oxidative phosphorylation.
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Overall Respiration Equation: 6O₂ + C₆H₁₂O₆ → 6CO₂ + 6H₂O + energy (ATP) Locations of each phase (plant and animal cells). Includes information on the breakdown of glucose as it moves from one part of the cell to another.
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Glycolysis: Two phases (energy investment, energy payoff) producing a net gain of 2 ATP and 2 NADH from starting glucose. Describes the location and products of each component of glycolysis.
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Pyruvate Oxidation: Occurs in mitochondrial matrix of eukaryotes. Produces Acetyl CoA, NADH, and CO₂. Explains energy and atom movement during pyruvate oxidation.
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Citric Acid Cycle: Takes place in mitochondrial matrix. Produces 1 ATP, 3 NADH, 1 FADH₂, and 2 CO₂ per cycle. Explains energy and atom movement during the citric acid cycle.
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Oxidative Phosphorylation: Electron transport chain (ETC) and chemiosmosis. The ETC creates a proton gradient across the inner mitochondrial membrane, driving ATP synthesis through chemiosmosis.
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Photosynthesis: Light-dependent reactions (thylakoid membranes) and light-independent reactions (Calvin cycle, stroma)
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Overall Photosynthesis Equation: 6CO₂+ 6H₂O + light energy → C₆H₁₂O₆ + 6O₂
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Photosynthesis Purpose: Converting light energy to chemical energy (glucose); producing oxygen.
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Light Reactions: Absorption of light energy, production of ATP and NADPH, water splitting to release O₂.
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Calvin Cycle: Carbon dioxide fixation, sugar production (G3P), using ATP and NADPH from light reactions.
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Enzyme Function and structure: Biological catalysts.
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Enzyme Variables: Temperature, pH, substrate concentration, and enzyme concentration.
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Enzyme Inhibitors: Competitive and noncompetitive.
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Photosynthesis-Respiration Relationship: Photosynthesis produces oxygen and glucose, while cellular respiration uses them. Both processes are interconnected. Their relationship is described in the equation.
Unit 2: Cell Communication, Reproduction, & Development
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Cell Communication Concepts: Ligand, receptor, conformational change, signal transduction, amplification, signaling cascade, phosphorylation cascade, kinase, second messenger.
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Cell Signaling Stages: Reception, signal transduction, and response; with reference to the signaling pathways used by cells in conjunction with the different types of receptors in the cell membrane.
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Ligand Types: Hydrophobic (e.g., steroid hormones) versus hydrophilic (e.g., peptide hormones).
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Reception Mechanisms: Hydrophilic ligands bind to cell-surface receptors; hydrophobic ligands bind to intracellular receptors.
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Receptor Types and Signaling Pathways: Ion channel-linked, G protein-linked, and enzyme-linked receptors; describing the different pathways. The effect of ligand binding on the receptor.
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Signal Relay and Amplification: Phosphorylation cascades and second messengers amplify the signal within the cell.
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Cellular Responses: Gene expression, cellular metabolism, cell growth, and apoptosis.
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Signal Termination: Essential to prevent uncontrolled responses. Methods include ligand breakdown, receptor endocytosis, dephosphorylation, and second-messenger uptake.
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Endocrine System Glands and Hormones: Names, locations, major hormones, and general functions of hypothalamus, pituitary, pineal, thyroid, thymus, pancreas, adrenal glands, ovaries, and testes. Provides information on how each type of hormone regulates different body systems.
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Reproduction - Spermatogenesis: Diploid spermatogonia undergo mitosis to produce more spermatogonia; then meiosis producing 4 sperm from each primary spermatocyte. Occurs in seminiferous tubules. Begins at puberty.
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Reproduction - Oogenesis: Begins in embryo with oocyte production. Primary oocytes arrest in prophase I before birth; at puberty, meiosis resumes one oocyte per cycle, forming secondary oocyte and polar bodies. Arrested at metaphase II until fertilization. Occurs in ovaries.
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Female Reproductive Structures: Ovaries, oviduct, uterus, endometrium, cervix, and vagina, outlining each structures function.
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Male Reproductive Structures: Testes, scrotum, epididymis, vas deferens, seminal vesicle, prostate, bulbourethral gland, urethra, and penis, outlining each structures function.
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Hormonal Regulation of Menstrual Cycle: FSH, LH, estrogen, and progesterone govern ovarian and uterine cycles. Explains the function of hormones for reproductive process and their regulation.
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Fertilization: Stages of sperm activation, enzyme release, sperm binding, and membrane fusion. Explains how fertilization occurs.
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Hormonal Birth Control: Overview of how hormonal methods work.
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Development: Zygote formation, morula, blastocyst, implantation, embryo/fetus definitions. Describes the process and formation of the placenta. Role of hormones (e.g., hCG, progesterone).
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Apoptosis: A form of programmed cell death crucial for development and maintenance.
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Parturition: The birthing process. Role of oxytocin and prostaglandins in uterine contractions.
Unit 3: Genetics
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Mendelian Genetics Terms: Gene, allele, genotype, phenotype, dominant, recessive, homozygous, heterozygous, complete dominance, codominance - different ways traits can combine.
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Mendel’s Hypotheses: Blending hypothesis (incorrect) versus particulate hypothesis (correct, traits inherited in discrete units).
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Punnett Squares: Used to predict offspring genotypes and phenotypes for one or two genes. Includes examples: complete dominance, incomplete dominance, codominance.
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Sex-Linked Genes: Inheritance patterns determined by genes on sex chromosomes.
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Pedigree Analysis: Analyzing family histories to determine inheritance patterns.
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Law of Independent Assortment: Genes on different chromosomes are inherited independently; explained by random chromosome alignment during meiosis I.
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Law of Segregation: Alleles for the same gene segregate during gamete formation; each gamete receives only one allele. Explained by chromosome separation in meiosis.
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Linked Genes: Genes located close together on the same chromosome tend to be inherited together.
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Chromosome Structure: Centromere, p arm, q arm; Locus definitions of location for genes on a chromosome; including chromosomal rearrangements (deletions, duplications, inversions, translocations)
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Aneuploidy and Nondisjunction: Aneuploidy is an abnormal number of chromosomes; nondisjunction is the failure of chromosomes to separate in meiosis, leading to an abnormal number of chromosomes in gametes.
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Karyotype: A visual representation of an organism's chromosomes.
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Environmental Impact on Phenotype: Environmental factors can influence the expression of a genotype.
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Genotype-Phenotype Relationship: Genotype (DNA) dictates phenotype (observable traits) through the processes of transcription and translation.
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