Podcast
Questions and Answers
What is the primary reason for the Earth's habitability?
What is the primary reason for the Earth's habitability?
What is the chemical formula for Aspartic acid?
What is the chemical formula for Aspartic acid?
Which of these is NOT an emergent property of water?
Which of these is NOT an emergent property of water?
What is the main characteristic of carbon that makes it so important for life?
What is the main characteristic of carbon that makes it so important for life?
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Which of the following molecules are NOT composed of carbon compounds?
Which of the following molecules are NOT composed of carbon compounds?
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What is the approximate percentage of water within a typical cell?
What is the approximate percentage of water within a typical cell?
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What is the significance of the pH of water within living systems?
What is the significance of the pH of water within living systems?
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What is the main factor contributing to the emergent properties of water?
What is the main factor contributing to the emergent properties of water?
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Which of the following elements are NOT among the four that make up 96% of living matter?
Which of the following elements are NOT among the four that make up 96% of living matter?
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Which of the following is NOT a class of biological macromolecule?
Which of the following is NOT a class of biological macromolecule?
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What is the name of the bond formed when two atoms share electrons?
What is the name of the bond formed when two atoms share electrons?
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What type of bond is responsible for the high specific heat of water?
What type of bond is responsible for the high specific heat of water?
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Which of the following statements about polymers is TRUE?
Which of the following statements about polymers is TRUE?
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What is the difference between a cation and an anion?
What is the difference between a cation and an anion?
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Which of the following is NOT a property of water?
Which of the following is NOT a property of water?
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Which of the following is NOT a major element found in living organisms?
Which of the following is NOT a major element found in living organisms?
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What type of bond links monosaccharides together?
What type of bond links monosaccharides together?
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What is the structural polysaccharide found in fungi?
What is the structural polysaccharide found in fungi?
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Which type of glycosidic linkage is found in amylose?
Which type of glycosidic linkage is found in amylose?
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What is the main difference between the Fischer and Haworth projections of carbohydrates?
What is the main difference between the Fischer and Haworth projections of carbohydrates?
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Where do plants store starch?
Where do plants store starch?
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Which of the following is a disaccharide?
Which of the following is a disaccharide?
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What is the main function of glycogen in animals?
What is the main function of glycogen in animals?
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What type of linkage is found in lactose?
What type of linkage is found in lactose?
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What distinguishes a hydrophobic amino acid from a hydrophilic amino acid?
What distinguishes a hydrophobic amino acid from a hydrophilic amino acid?
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Which of the following statements accurately describes the type of bond that connects amino acids in a protein chain?
Which of the following statements accurately describes the type of bond that connects amino acids in a protein chain?
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What is the significance of the amino (N) and carboxyl (C) termini in a protein chain?
What is the significance of the amino (N) and carboxyl (C) termini in a protein chain?
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Which amino acid is known to introduce a kink into a protein structure?
Which amino acid is known to introduce a kink into a protein structure?
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What type of bond is responsible for forming a disulfide bridge between two cysteine residues in a protein?
What type of bond is responsible for forming a disulfide bridge between two cysteine residues in a protein?
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Which statement accurately describes the primary structure of a protein?
Which statement accurately describes the primary structure of a protein?
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How do amino acids contribute to the overall structure and function of a protein?
How do amino acids contribute to the overall structure and function of a protein?
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Why are some amino acids considered essential?
Why are some amino acids considered essential?
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What is the primary process described for synthesizing a polymer?
What is the primary process described for synthesizing a polymer?
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Which of the following best describes hydrolysis?
Which of the following best describes hydrolysis?
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Which macromolecule is generally not considered a true polymer?
Which macromolecule is generally not considered a true polymer?
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What is the ratio of hydrogen to oxygen to carbon in simple sugars?
What is the ratio of hydrogen to oxygen to carbon in simple sugars?
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What is the general term for the single units that make up polymers?
What is the general term for the single units that make up polymers?
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Which of the following is NOT a type of biological macromolecule mentioned?
Which of the following is NOT a type of biological macromolecule mentioned?
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Simple sugars are primarily used by organisms for which purpose?
Simple sugars are primarily used by organisms for which purpose?
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In the synthesis of a longer polymer from unlinked monomers, what is removed during the dehydration reaction?
In the synthesis of a longer polymer from unlinked monomers, what is removed during the dehydration reaction?
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What distinguishes prions from other types of pathogens?
What distinguishes prions from other types of pathogens?
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Which of the following diseases is associated with prion pathogens?
Which of the following diseases is associated with prion pathogens?
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How do prions propagate within a healthy organism?
How do prions propagate within a healthy organism?
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Which of the following best describes proteins in biological systems?
Which of the following best describes proteins in biological systems?
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What is a common feature of the diseases caused by prions?
What is a common feature of the diseases caused by prions?
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Study Notes
Biology 1 - Cells, Molecular Biology and Genetics (BIOL 1000)
- This is a course on cells, molecular biology, and genetics, taught by Dr. Michael Cardinal-Aucoin during Winter 2025 at York University.
- Students are expected to know about proteins, carbohydrates, lipids, and nucleic acids consumed as breakfast.
- The course will cover the building blocks of life including chemistry of life, biological macromolecules, polymers, carbohydrates, lipids, proteins, and nucleic acids.
Review Chapter 2
- Building Blocks: Matter, element, atom, neutron, proton, electron, nucleus, atomic mass, atomic number, isotope, valence electron, ion (cation, anion)
- Bonds: Ionic, covalent (non-polar, polar), electronegativity, hydrogen, van der Waals forces
- Chemical Reactions: Reactants, products, reversible, equilibrium, specificity, properties of water (polarity, cohesion, adhesion, high specific heat), functional groups
The Molecules of Life
- All cells are made of four classes of biological macromolecules: carbohydrates, lipids, nucleic acids, and proteins.
- All these macromolecules have a carbon skeleton.
- The macromolecules have a wide variety of ways to be built and combined.
The Chemistry of Life
- 20-25% of 92 elements are crucial for life.
- Approximately 96% of living material is made up of carbon, hydrogen, oxygen, and nitrogen.
- Other elements like calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium make up the remaining 4%.
Table 2.1 Elements in the Human Body (Summary)
- Oxygen is the most abundant element in the human body (65%).
- Other percentages of elements listed for the human body, including water.
Water and Life
- Water is the biological medium on Earth, crucial for life's evolution.
- All living things need water more than any other substance.
- Most cells are surrounded by water, making up 70-95% of a cell's composition.
- Cells are essentially bags of molecules dissolved in water, and the availability of liquid water makes Earth habitable.
Summary
- The four emergent properties of water (expansion upon freezing, cohesion/adhesion, moderation of temperature, and versatility as a solvent) are mainly due to its polarity and formation of hydrogen bonds; important for life on Earth.
- The pH of water is tightly regulated in living systems.
The Backbone of Life
- Living things are mainly composed of carbon-based compounds.
- Carbon's ability to form complex and diverse molecules makes it a key component of life and abundant in the cosmos.
- Proteins, DNA, carbohydrates, and other molecules that differentiate living matter are all built from carbon compounds.
A Note about Formulae
- Aspartic acid is an amino acid, a building block of proteins.
- Chemical formula (C4H7NO4)
- Condensed structural formula (NH2CH(CH2COOH)COOH)
- A visual representation of its structure showing the bonds and atoms.
Diversity of chemical functional groups constructed with carbon.
- Various chemical groups commonly connected to carbon atoms are mentioned, along with their properties.
The Molecules of Life (Summary)
- Carbohydrates: provide energy and support structural components.
- Lipids: make up cell membranes, store energy, and serve as signaling molecules.
- Nucleic acids: store and transmit genetic information.
- Proteins: provide structural support and act as catalysts (enzymes) in chemical reactions.
Polymers (Summary)
- Most biological macromolecules are polymers, made from repeating units called monomers.
- Proteins, for instance, are made of monomers, amino acids.
- Polymers are assembled and disassembled through dehydration and hydrolysis reactions respectively.
Carbohydrates
- Simple sugars have a 1:2:1 C:H:O ratio (CH2O), making them essential energy sources for many life forms.
- Examples: glucose, fructose, ribose, etc.
- Monosaccharides differ based on carbon number (triose, tetrose, pentose, hexose) and C=O position (aldose, ketose).
- Numerous structural variations exist in carbohydrate polymers formed from these monomers.
- Glycosidic bonds link monosaccharides to create disaccharides and polysaccharides such as starch, glycogen, and cellulose.
Disaccharides
- Disaccharides comprise two monosaccharides linked together via glycosidic bonds.
- Important examples include sucrose (glucose + fructose), lactose (glucose + galactose), and maltose (glucose + glucose).
- Disaccharides have crucial roles in the transport and storage of sugars within organisms.
Polysaccharides
- Polysaccharides consist of long linked monosaccharide chains.
- Common examples are starch, glycogen, and cellulose.
- Starch (amylose and amylopectin) in plants along with glycogen in animals and fungi, serve as energy storage molecules.
- Cellulose in plants provides structural support, while chitin plays a similar role in fungi.
Lipids
- Lipids differ from proteins, nucleic acids, and carbohydrates since the units aren't repeating monomers.
- Lipids are hydrophobic.
- Important lipid types include neutral fats (or triglycerides), phospholipids (crucial membrane constituents), and steroids (for hormones and membranes).
- Neutral fats are for energy storage, insulation, protection of internal organs.
- Phospholipids form cell membranes.
- Steroids are hormones and components of membranes
Nucleic Acids
- Nucleic acids are made of nucleotides composed of a nitrogenous base, a pentose (5-carbon sugar), and a phosphate group.
- Nucleotides are linked together by phosphodiester bonds during dehydration synthesis creating a chain.
- DNA stores hereditary information in a double helix.
- RNA carries information from DNA and plays a role in protein synthesis.
- The Central Dogma describes DNA instructions being transformed into proteins with the aid of mRNA
Proteins
- Proteins are polypeptides or polymers formed by amino acid subunits.
- Important protein functions include catalysis (enzymes), defense (antibodies), transport (hemoglobin), storage (ovalbumin) and movement.
- Protein functions are related to their structures.
- Different protein structures include (Primary, Secondary, Tertiary, and Quaternary).
Denaturation
- The tertiary structure of a protein determines its function.
- Proteins can be denatured or disrupted through high temperatures or chemical treatments, causing a loss of function.
Quaternary Structure
-
Some proteins consist of multiple polypeptide chains, forming a quaternary structure.
-
Hemoglobin in red blood cells, a good example, is composed of four subunits (2α and 2β).
Proteins
- Some amino acids are essential, meaning they must be obtained from diet.
Summary
- The course will touch on the various aspects of the chemistry of life, covering polymers (carbohydrates, lipids, nucleic acids, and proteins), summarizing each class's structure, function, and importance.
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Description
Test your knowledge on the fundamental principles of biology and the chemistry of life with this quiz on Chapter 2. Questions cover topics such as water's properties, carbon's role in life, and chemical bonding. Perfect for students looking to assess their understanding of essential biological concepts.