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Questions and Answers
What are the components of a phospholipid?
What are the components of a phospholipid?
- One fatty acid, a triglyceride backbone, and a phosphate group
- Two fatty acids, glycerol, a phosphate group, and an alcohol group (correct)
- Two fatty acids, a starch molecule, and a nitrogen group
- Glycerol, three fatty acids, and a phosphate group
What functions do membrane carbohydrates like glycolipids serve?
What functions do membrane carbohydrates like glycolipids serve?
- They are involved in cell recognition and adhesion. (correct)
- They promote oxidation reactions in the cell membrane.
- They contribute to lipid digestion in the cell.
- They store energy for the cell.
Which type of glycolipid is found in plasma membranes and is important for blood type determination?
Which type of glycolipid is found in plasma membranes and is important for blood type determination?
- Neutral glycolipids
- Galactolipids
- Cerebrosides (correct)
- Gangliosides
What is the primary component of the head group in glycolipids?
What is the primary component of the head group in glycolipids?
How do glycolipids protect the plasma membrane in eukaryotic cells?
How do glycolipids protect the plasma membrane in eukaryotic cells?
Which function is NOT attributed to glycolipids in eukaryotic cells?
Which function is NOT attributed to glycolipids in eukaryotic cells?
What is one function of cholesterol in the cell membrane?
What is one function of cholesterol in the cell membrane?
Which glycolipid acts as a receptor for cholera toxin?
Which glycolipid acts as a receptor for cholera toxin?
Which term best describes the arrangement of components in the fluid mosaic model?
Which term best describes the arrangement of components in the fluid mosaic model?
What role do glycoproteins play in cell membranes?
What role do glycoproteins play in cell membranes?
How do saturated hydrocarbon tails affect membrane fluidity?
How do saturated hydrocarbon tails affect membrane fluidity?
What is the significance of having unsaturated hydrocarbon tails in phospholipids?
What is the significance of having unsaturated hydrocarbon tails in phospholipids?
What happens to the lipid bilayer when heated?
What happens to the lipid bilayer when heated?
What does membrane fluidity primarily depend on?
What does membrane fluidity primarily depend on?
What characteristic of membranes is associated with their asymmetry?
What characteristic of membranes is associated with their asymmetry?
What is one consequence of cholesterol's presence in animal cell membranes?
What is one consequence of cholesterol's presence in animal cell membranes?
What is the primary function of the cell membrane?
What is the primary function of the cell membrane?
What is the chemical nature of the heads and tails of the phospholipids in the cell membrane?
What is the chemical nature of the heads and tails of the phospholipids in the cell membrane?
Which types of molecules can pass through the cell membrane most easily?
Which types of molecules can pass through the cell membrane most easily?
Which of the following statements about the structure of cell membranes is true?
Which of the following statements about the structure of cell membranes is true?
What is the primary effect of Cholera toxin on intestinal cells?
What is the primary effect of Cholera toxin on intestinal cells?
What type of glycosylation involves the attachment of glycans to the nitrogen of asparagine?
What type of glycosylation involves the attachment of glycans to the nitrogen of asparagine?
What are amphipathic molecules?
What are amphipathic molecules?
Which of the following is NOT a function of glycoproteins?
Which of the following is NOT a function of glycoproteins?
What additional component is only found in the membranes of eukaryotic cells?
What additional component is only found in the membranes of eukaryotic cells?
What type of technique is freeze-fracture, and what does it achieve?
What type of technique is freeze-fracture, and what does it achieve?
What component characterizes the hydrophilic head of cholesterol?
What component characterizes the hydrophilic head of cholesterol?
Which of the following molecules are unable to move through the cell membrane by themselves?
Which of the following molecules are unable to move through the cell membrane by themselves?
What is the role of lymphocytes in the immune system?
What is the role of lymphocytes in the immune system?
Which of the following statements about glycoproteins is accurate?
Which of the following statements about glycoproteins is accurate?
What distinguishes antigens from other proteins?
What distinguishes antigens from other proteins?
How does the immune system ensure a wide variety of pathogen detection?
How does the immune system ensure a wide variety of pathogen detection?
Flashcards
Glycoprotein
Glycoprotein
A type of protein that has sugars attached to it.
Glycan
Glycan
A type of sugar chain that can be attached to lipids or proteins.
Glycosylation
Glycosylation
The process of attaching a glycan to a protein or lipid.
N-glycosylation
N-glycosylation
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O-glycosylation
O-glycosylation
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Antigen
Antigen
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Lymphocyte
Lymphocyte
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Antigen Receptor
Antigen Receptor
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Phospholipid
Phospholipid
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Sphingolipid
Sphingolipid
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Glycocalyx
Glycocalyx
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Glycolipid Function 1: Cell Recognition
Glycolipid Function 1: Cell Recognition
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Glycolipid Function 2: Cell Adhesion
Glycolipid Function 2: Cell Adhesion
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Glycolipid Function 3: Cell Signaling
Glycolipid Function 3: Cell Signaling
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Glycolipid Function 4: Membrane Protection
Glycolipid Function 4: Membrane Protection
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Glycolipid Function 5: Entry Points for Toxins
Glycolipid Function 5: Entry Points for Toxins
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Freeze-fracture
Freeze-fracture
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Lipid Bilayer
Lipid Bilayer
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Fluidity of a lipid bilayer
Fluidity of a lipid bilayer
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Asymmetry of a lipid bilayer
Asymmetry of a lipid bilayer
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Amphipathic molecules
Amphipathic molecules
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Glycolipids
Glycolipids
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Cholesterol
Cholesterol
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What is the function of cholesterol in cell membranes?
What is the function of cholesterol in cell membranes?
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What does 'membrane fluidity' refer to?
What does 'membrane fluidity' refer to?
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What does 'membrane asymmetry' refer to?
What does 'membrane asymmetry' refer to?
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What is the fluid mosaic model?
What is the fluid mosaic model?
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How do saturated hydrocarbon tails affect membrane fluidity?
How do saturated hydrocarbon tails affect membrane fluidity?
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How do unsaturated hydrocarbon tails affect membrane fluidity?
How do unsaturated hydrocarbon tails affect membrane fluidity?
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How does cholesterol affect membrane fluidity in animal cells?
How does cholesterol affect membrane fluidity in animal cells?
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What are the gel and fluid phases of a lipid bilayer, and how do they relate to temperature?
What are the gel and fluid phases of a lipid bilayer, and how do they relate to temperature?
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Study Notes
Cell Membrane
- The cell membrane surrounds and protects all cells, separating their internal components from the outside environment.
- It acts as a selective barrier, controlling the import and export of molecules thanks to transport proteins.
- The membrane can move and expand.
- It receives and processes information, facilitating cell communication.
Cell Membrane Structure
- The membrane is primarily composed of a lipid bilayer.
- Phospholipids form the bilayer, consisting of hydrophilic (water-loving) heads and hydrophobic (water-fearing) tails.
- Hydrophobic molecules pass easily through the membrane, while hydrophilic molecules do not.
- Smaller molecules and larger hydrophobic molecules move across easily (e.g., O2, CO2, H2O).
- Ions and hydrophilic molecules larger than water, as well as proteins, do not readily move without assistance.
Membrane Lipids
- Phospholipids: the most abundant, including saturated or unsaturated fatty acids, glycerol, a phosphate group, and an alcohol group (choline, ethanolamine, serine, or inositol).
- Glycolipids: bound to carbohydrates.
- Cholesterol: found only in eukaryotes.
Properties of Lipids
- All lipids have both hydrophilic and hydrophobic properties.
- The behavior of lipids impacts the membrane's fluidity.
Lipid Bilayer Characteristics
- Properties: the lipid forms, fluidity, and asymmetry.
- Types of lipids: membrane lipids.
Membrane Proteins
- Integral membrane proteins are embedded in the lipid bilayer.
- Peripheral membrane proteins are loosely associated with the membrane surface.
Carbohydrates and Cell Coat
- Carbohydrates are attached to either lipids or proteins.
- They are part of the cell membrane's glycocalyx.
Freeze-Fracture
- A technique to split cell membranes along the middle of the phospholipid bilayer, revealing internal membrane protein structure.
Fluidity
- The movement of lipids within the cell membrane.
- Membrane flexibility influenced by lipid composition.
Effect of Lipids on Fluidity
- Saturated hydrocarbon tails pack tightly together, making the membrane less fluid.
- Unsaturated hydrocarbon tails have kinks, preventing tight packing and enhancing fluidity.
- Cholesterol embedded in animal cell membranes regulates fluidity and permeability.
Effect of Temperature on Fluidity
- Heating generally increases fluidity.
- Membranes transition from a gel-like to a fluid-like state at different temperatures.
Fluid Mosaic Model
- Explains the structure of the cell membrane as a fluid mosaic, a combination of components, including phospholipids, proteins, cholesterol, and carbohydrates.
Function of Cholesterol
- Regulates cell membrane fluidity and permeability.
Glycocalyx
- Carbohydrates on the cell membrane's surface (either glycolipids, or glycoproteins), involved in cell-cell recognition, adhesion, and signaling.
Glycolipids
- Have a hydrophobic tail and a hydrophilic head (carbohydrate).
- The hydroxyl group is crucial for causing the head's polarity.
- Function in cell-cell recognition processes in eukaryotic cells and may provide protection against harsh conditions.
Glycoproteins
- Proteins with attached glycans (carbohydrate chains).
- Commonly synthesized in endoplasmic reticulum (ER) post-translationally.
- Involved in cell-cell recognition, immune responses, adhesion, and signaling.
Function of Glycoproteins
- Essential for immune system function, cell identification, and various bodily processes (including mucus creation for protection).
Blood Type Glycolipids
- An example of how glycolipids mediate cell interactions with the surrounding environment.
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