Final A+P Multiple Choice Pt.2
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Questions and Answers

What is the primary function of mitochondria in a cell?

  • Regulates gene expression
  • Synthesize proteins
  • Digests macromolecules
  • Produces ATP (correct)

Which organelle is responsible for modifying, sorting, and packaging proteins and lipids?

  • Lysosome
  • Golgi apparatus (correct)
  • Centrosome
  • Ribosome

How do positive feedback mechanisms differ from negative feedback mechanisms?

  • Negative feedback produces a cascade of responses until a set point is attained.
  • Positive feedback moves a variable back to its set point.
  • Negative feedback amplifies changes to move away from the set point.
  • Positive feedback amplifies changes to move toward a goal. (correct)

Which of the following statements is true about cations and anions?

<p>Anions are produced by a gain of electrons. (A)</p> Signup and view all the answers

What is the main purpose of vesicles in a cell?

<p>Transport and secrete substances (A)</p> Signup and view all the answers

Which type of bond is formed by the sharing of electron pairs between atoms?

<p>Covalent bond (A)</p> Signup and view all the answers

What is the relationship between atoms, elements, and compounds?

<p>Atoms combine to form elements, which can combine to form compounds. (A)</p> Signup and view all the answers

Which macromolecule is primarily responsible for storing genetic information?

<p>Nucleic acids (A)</p> Signup and view all the answers

What is the primary function of chemoresceptors?

<p>To sense changes in chemical concentrations. (D)</p> Signup and view all the answers

What role do synaptic vesicles play in neuron function?

<p>They store and release neurotransmitters at the synapse. (C)</p> Signup and view all the answers

Which ion's concentration is higher outside the neuron at rest, favoring its entry during an action potential?

<p>Na+ (C)</p> Signup and view all the answers

What is the primary role of voltage-gated ion channels in neurons?

<p>To allow ions to move based on changes in membrane voltage. (A)</p> Signup and view all the answers

Which type of muscle is controlled by the autonomic nervous system?

<p>Cardiac muscle in the heart. (A)</p> Signup and view all the answers

What is the primary function of the stratum corneum in the epidermis?

<p>Protection against abrasion and infection (C)</p> Signup and view all the answers

During which phase of the cell cycle does DNA replication occur?

<p>S phase (D)</p> Signup and view all the answers

What distinguishes the dermis from the epidermis?

<p>Presence of nerves and blood vessels (A)</p> Signup and view all the answers

What is one of the characteristics of the hypodermis?

<p>Acts as a cushioning layer of fat and connective tissue (D)</p> Signup and view all the answers

Which phase of mitosis is characterized by the alignment of chromosomes along the cell equator?

<p>Metaphase (D)</p> Signup and view all the answers

What happens to chromosomes during anaphase of mitosis?

<p>Sister chromatids are pulled to opposite poles (D)</p> Signup and view all the answers

Which layer of the integumentary system contains dermal papillae?

<p>Papillary layer (A)</p> Signup and view all the answers

Which of the following is NOT a primary function of the skin?

<p>Secretion of hormones (D)</p> Signup and view all the answers

What is the primary output of glycolysis?

<p>2 pyruvate (B)</p> Signup and view all the answers

Where does the Krebs Cycle take place in a cell?

<p>Mitochondria (B)</p> Signup and view all the answers

Which type of reaction absorbs energy and is considered non-spontaneous?

<p>Endergonic (B)</p> Signup and view all the answers

What is the role of competitive inhibitors in enzymatic reactions?

<p>They bind to the active site of an enzyme. (C)</p> Signup and view all the answers

Which component is NOT produced during the Electron Transport Chain?

<p>Pyruvate (A)</p> Signup and view all the answers

What is the result of K+ efflux during repolarization?

<p>Hyperpolarization (A)</p> Signup and view all the answers

Which body system is primarily responsible for producing body movements?

<p>Muscular System (B)</p> Signup and view all the answers

What is formed from the bond between deoxyribonucleotides in DNA structure?

<p>Phosphodiester bonds (B)</p> Signup and view all the answers

Which stage of cellular respiration involves the conversion of pyruvate into AcetylcoA?

<p>Intermediate Stage (C)</p> Signup and view all the answers

Which step follows the 'initiation' phase in the transcription of RNA?

<p>Elongation (D)</p> Signup and view all the answers

What occurs during mRNA splicing?

<p>Removing unnecessary parts (B)</p> Signup and view all the answers

What is the primary function of the cardiovascular system?

<p>Delivers oxygen and nutrients (C)</p> Signup and view all the answers

What is the role of tRNA in translation?

<p>Aligns amino acids with codons (B)</p> Signup and view all the answers

What is the start codon that signifies the beginning of protein synthesis?

<p>AUG (A)</p> Signup and view all the answers

During which phase of cell division does DNA replication occur?

<p>Interphase (B)</p> Signup and view all the answers

What is added to the end of the mRNA during the polyadenylation process?

<p>Poly-A tail (B)</p> Signup and view all the answers

Which structure is responsible for coordinating movement and balance?

<p>Cerebellum (C)</p> Signup and view all the answers

What is the primary function of the corpus callosum?

<p>Connects the left and right cerebral hemispheres (B)</p> Signup and view all the answers

Which type of muscle tissue is striated and involuntary, found in the walls of the heart?

<p>Cardiac muscle (A)</p> Signup and view all the answers

What is the role of the medulla oblongata in the body?

<p>Controls breathing, heart rate, and blood pressure (C)</p> Signup and view all the answers

Which part of the long bone is responsible for housing bone marrow?

<p>Medullary cavity (A)</p> Signup and view all the answers

During muscle contraction, what initiates the release of Ca++ ions from the sarcoplasmic reticulum?

<p>Nerve impulse (A)</p> Signup and view all the answers

Which structure is primarily involved in processing sensory information such as touch and temperature?

<p>Parietal lobe (D)</p> Signup and view all the answers

What is the primary function of the pituitary gland?

<p>Producing and releasing hormones (D)</p> Signup and view all the answers

Flashcards

Glycolysis

The breakdown of glucose into pyruvate, producing ATP and NADH.

Cellular Respiration

A metabolic pathway that breaks down glucose to produce ATP.

Nucleus function

Controls cell activities, regulates gene expression, holds DNA.

Competitive Inhibitor

A molecule that resembles a substrate and binds to the active site of an enzyme, blocking the substrate from binding.

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Mitochondria function

Produces ATP (energy) for the cell.

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Exergonic Reaction

A reaction that releases energy.

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Endergonic Reaction

A reaction that absorbs energy.

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Positive Feedback

Amplifies a change; moves variable further from set point, until an event occurs

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Negative Feedback

Counteracts a change to maintain homeostasis, moves a variable toward the set point.

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Enzyme

A biological catalyst that speeds up chemical reactions.

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Anabolism

Building large molecules from smaller ones.

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Electron charge

Negatively charged.

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Catabolism

Breaking down large molecules into smaller ones.

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Atomic Mass

Sum of protons and neutrons in an atom.

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Atomic Number

Number of protons in an atom.

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Organic Compounds

Contain carbon and are part of living organisms.

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What do photoreceptors do?

They detect light stimuli in the eye and convert them into electrical signals sent to the brain.

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What are the types of effectors controlled by the nervous system?

Muscles: Skeletal (voluntary), Smooth (involuntary). Glands: Release hormones.

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What is the role of dendrites?

They receive electrical signals from other neurons via synapses and carry them to the cell body.

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What do ions do in neurons?

They create electrical signals by moving across the neuron's membrane, which allows for information transmission.

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What is the function of the phospholipid bilayer in neurons?

It acts as a selective barrier, controlling what enters and exits the cell, and maintaining the electrical potential for signal transmission.

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Repolarization

The movement of potassium ions out of a neuron, leading to a decrease in membrane potential.

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Depolarization

A change in membrane potential from resting to a more positive value, caused by the influx of sodium ions (Na+).

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Hyperpolarization

A change in membrane potential from resting to a more negative value, caused by the efflux of potassium ions (K+).

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Nucleotide

The monomer of DNA, composed of a nitrogenous base, a sugar, and a phosphate group.

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Transcription

The process of converting DNA instructions into mRNA.

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RNA polymerase

Enzyme that builds RNA molecules by adding ribonucleotides.

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Codon

A three-nucleotide sequence in mRNA that codes for a specific amino acid.

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Translation

The process of converting mRNA instructions into a polypeptide chain (protein).

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Frontal Lobe

Responsible for voluntary movement, language processing, social behavior, and emotional regulation.

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Parietal Lobe

Processes sensory information such as touch, temperature, pressure, and pain.

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Brainstem

Controls vital functions like breathing, consciousness, blood pressure, heart rate, and sleep.

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Corpus Callosum

Connects the left and right hemispheres of the brain, facilitating communication between them.

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Hippocampus

Essential for memory, learning, and spatial navigation.

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Cerebellum

Coordinates movement and balance, also involved in language, attention, and vision.

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Osteoblast

A bone cell responsible for building new bone tissue.

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Osteoclast

A bone cell responsible for breaking down old bone tissue.

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What are the phases of Interphase?

Interphase is the period of time between cell divisions where the cell prepares for division. It consists of three phases: G1, S, and G2.

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What happens during the G1 phase?

The G1 phase is the first phase of Interphase. It is characterized by cell growth and the production of new organelles. Centrioles also replicate to create two pairs.

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What happens during the S phase?

The S phase is the second phase of Interphase. It is characterized by the replication of DNA, ensuring that each daughter cell receives a complete set of chromosomes.

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What happens during the G2 phase?

The G2 phase is the final phase of Interphase. It is characterized by the completion of centriole replication and the synthesis of enzymes needed for mitosis.

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Prophase

The first stage of mitosis, characterized by chromatin condensing into chromosomes, the breakdown of the nuclear membrane, the movement of centrioles to opposite poles, and the formation of the spindle apparatus.

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Metaphase

The second stage of mitosis where chromosomes line up along the center of the cell, and spindle fibers attach to the centromeres of each chromosome.

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Anaphase

The third stage of mitosis where sister chromatids separate and are pulled apart by spindle fibers towards opposite poles of the cell.

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Telophase

The final stage of nuclear division in mitosis, characterized by the reformation of the nuclear membrane around each set of chromosomes at the poles, the decondensation of chromosomes, and the formation of two distinct nuclei.

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Study Notes

Cell Organelles

  • Nucleus: Controls cell activities, regulates gene expression, synthesizes RNA.
  • rER (Rough Endoplasmic Reticulum): Site of protein synthesis.
  • SER (Smooth Endoplasmic Reticulum): Synthesizes lipids, detoxifies toxins, stores calcium ions.
  • Mitochondria: Produces ATP, the cell's energy currency.
  • Golgi apparatus: Modifies, sorts, and packages proteins & lipids.
  • Lysosome: Digests macromolecules and microorganisms, removes damaged proteins.
  • Centrosomes: Organizes microtubules, facilitates cell division.
  • Proteosomes: Degrades unneeded or damaged proteins.
  • Cytoskeleton: Provides structural support, facilitates movement.

Ribosomes

  • Synthesize proteins that are used within the cytosol.
  • Ribosomes (free) transport materials or secrete substances, digest materials.

Homeostasis

  • Maintains a stable internal environment, even when external conditions change.
  • Regulates body temperature, blood glucose levels, etc.
  • Positive feedback amplifies changes, moving them further from the initial state; examples include blood clotting, childbirth.
  • Negative feedback returns a variable to its set point, counteracts a change, examples include regulating body temperature.

Atoms and Elements

  • Atoms are the smallest particle of a substance and cannot be broken chemically.
  • Atoms contain protons, neutrons, and electrons.
  • Elements are simple substances made of one type of atom that cannot be broken down into smaller pieces.
  • All atoms of the same element have the same number of protons.

Organic and Inorganic Compounds

  • Organic compounds contain carbon and are part of living organisms; examples include sugars, carbohydrates, proteins, lipids, nucleic acids.
  • Inorganic compounds do not contain carbon and are often found in non-living matter; examples include water, salts, acids, and bases.

Metabolism and Cellular Respiration

  • Metabolism is all chemical reactions inside a living organism.
  • Cellular respiration is a metabolic pathway that breaks down glucose to produce ATP.
  • Cellular respiration has 4 stages: glycolysis, intermediate stage, citric acid cycle, and the electron transport chain.

Anabolism and Catabolism

  • Anabolism involves building larger molecules from smaller molecules.
  • Catabolism involves breaking down larger molecules into smaller molecules.

Organization of Living Things

  • Levels from smallest to largest: chemical, cellular, tissue, organ, organ system, organismal.

Body Systems

  • Integumentary: protection, sensation, temperature regulation.
  • Skeletal: support, movement, and protection.
  • Muscular: produces body movements.
  • Nervous: controls muscles and some glands.
  • Endocrine: secretes hormones to control digestive processes, reproductive function, and homeostasis.
  • Cardiovascular: delivers oxygen, nutrients, and hormones, transports and filters lymph.
  • Respiratory: exchanges gases between blood and air.
  • Urinary: filters blood and removes waste products.
  • Digestive: digests, absorbs, and expels products.
  • Male Reproductive: produces sex cells and hormones.
  • Female Reproductive: produces sex cells and hormones.

Common Elements in the Body

  • Oxygen (O)
  • Carbon (C)
  • Hydrogen (H)
  • Nitrogen (N)

Plasma Membrane

  • Structure: phospholipid bilayer with hydrophilic heads and hydrophobic tails.
  • Function: regulates what enters and exits the cell.

Macromolecule and Polymer

  • Macromolecule: large complex molecules made of smaller molecules.
  • Monomer: small units that make up larger molecules.
  • Polymers: chains of monomers linked together.
  • Bonds: hold monomers together, examples include hydrogen bonds, ionic bonds, and covalent bonds.

REDOX Reactions

  • Redox Reactions: involve the transfer of electrons from one chemical structure to another.

Membrane Transport

  • Passive Transport: movement of molecules across the cell membrane without energy; examples include diffusion and osmosis.
  • Active Transport: movement of molecules across the cell membrane using energy; examples include pumps.

Osmosis

  • Osmosis: the movement of water across a selectively permeable membrane to equalize the concentration of solutes.

Diffusion

  • Simple diffusion - the movement of molecules or ions from an area of high concentration to an area of low concentration.
  • Facilitated diffusion - the movement of molecules or ions across a cell membrane from an area of high concentration to an area of low concentration facilitated by proteins that assist the passage of these ions or molecules.

Symport vs. Antiport

  • Symport: transports two substances in the same direction.
  • Antiport: transports two substances in opposite directions.

Vesicular Transport

  • Exocytosis: releases substances from inside the cell by fusing vesicles with the cell membrane.
  • Endocytosis: takes in substances from outside the cell by engulfing them with cell membrane.

Receptor-Mediated Transport

  • Receptor-mediated transport is a type of endocytosis that is highly specific for the substance being taken into the cell.

Membrane Potential

  • Difference in electrical charge across the cell membrane.

AP Sequence of Events

  • Resting potential (-70mV)
  • Depolarization (voltage across the membrane becomes positive)
  • Repolarization (voltage across the membrane returns to its negative resting value)
  • Hyperpolarization (voltage across the membrane temporarily becomes more negative than the resting value)

Nucleus

  • DNA is located in the nucleus, in the form of chromatin or chromosomes.

DNA Structure

  • Monomer: nucleotide
  • Polymer: DNA (deoxyribonucleic acid)
  • Bonds: phosphodiester bonds

Transcription of RNA

  • Initiation: RNA polymerase binds to a promoter region on a DNA strand.
  • Elongation: RNA polymerase reads the DNA template and creates a RNA molecule.
  • Termination: RNA polymerase reaches a terminator sequence and stops creating the RNA molecule.

Translation

  • Translation: mRNA codons are translated into amino acids by tRNA.
  • tRNA aligns amino acids with their corresponding codons in mRNA.

Cell Division - Mitosis

  • Interphase: DNA replication.
  • Prophase: chromatin condenses into chromosomes, nuclear envelope breaks down, centrioles move to opposite poles.
  • Metaphase: chromosomes align along the center of the cell, spindle fibers attach to centromeres.
  • Anaphase: sister chromatids separate and are pulled to opposite poles.
  • Telophase: nuclear envelope reforms around each set of chromosomes, chromosomes decondense, two separate nuclei form.
  • Cytokinesis: cell cytoplasm divides into two daughter cells.

Cell Cycle

  • Interphase: G1, S, & G2. Preparation for and replication prior to cell division.
  • Mitosis: cell division of somatic cells.

Integument (skin)

  • Epidermis (top layer): protects against water loss and substances/organisms; stratified squamous epithelium, provides a barrier.
  • Dermis (deeper layer): contains blood, lymph vessels, nerves, hair follicles, and sweat glands; dense irregular connective tissue.
  • Hypodermis (subcutaneous): fat and connective tissue, not part of the integument or skin.

Composition of Dermis

  • Connective tissue—collagen, elastic fibers, blood vessels, nerves.
  • Sweat glands, sebaceous glands, hair follicles, nail roots, and arrector pili.

Hair Follicle & Hair

  • Keratinized cells growing from hair follicles.
  • Structure and general functions.

Nervous System

  • Brain, spinal cord, and nerves.

General Organization of Nervous System

  • Sensory neurons (afferent): transmit signals from receptors to the CNS.
  • Motor neurons (efferent): transmit signals from the CNS to effectors.

Neuron Structures

  • Dendrites: receive signals from other neurons.
  • Axons: transmit signals to other neurons.

Synaptic Transmission

  • Neurotransmitters: chemical messengers.
  • Synaptic vesicles: store neurotransmitters.

General Functions of Cerebrum

  • Conscious thought and intellectual function.

Hypothalamus

  • Regulates body temperature, controls autonomic functions (e.g., heart rate, blood pressure, respiration) and the endocrine system.

Osteoblast

  • Builds bone.

Osteoclast

  • Breaks down bone.

Osteoprogenitor Cells

  • Stem cells for bone formation.

Muscle Tissue

  • Skeletal: striated, voluntary.
  • Smooth: involuntary, lines the walls of hollow organs.
  • Cardiac: striated, involuntary, found in the heart.

Process of Muscle Contraction

  • Nerve impulse (AP) begins.
  • AP travels along muscle fiber membrane (sarcolemma)
  • Excitation-contraction coupling. Ca2+ is released from sarcoplasmic reticulum.
  • Cross bridge formation. Myosin heads attach to actin fibers.
  • Powerstroke. Myosin heads pivot, pulling actin fibers.
  • Detachment. ATP binds to myosin heads which detaches from actin.
  • Relaxation. Nerve signal stops, Ca2+ levels decrease, tropomyosin returns to original position.

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