Biological Chemistry: Evolution of Life

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Questions and Answers

What initially provided the necessary monomers and energy for polymerization reactions in early life?

  • Enzymatic systems
  • The prebiotic soup (correct)
  • Abundant reducing agents
  • Photosynthetic organisms

Why did early organisms develop enzymatic systems?

  • To break down complex polymers
  • To utilize sunlight
  • To produce molecular oxygen
  • To synthesize essential substances from simpler precursors (correct)

Which reducing agent was initially used in photosynthesis before water?

  • H2S (correct)
  • H2O
  • CO2
  • O2

What was a significant by-product of using water as a reducing agent in photosynthesis that ultimately influenced the atmosphere?

<p>O2 (C)</p> Signup and view all the answers

What major atmospheric feature was formed due to the increase of oxygen from photosynthesis?

<p>The ozone layer (A)</p> Signup and view all the answers

According to the colonization theory, how might life have been transported to Earth?

<p>By living spores propelled by light pressure from distant stars. (D)</p> Signup and view all the answers

What does the term 'Panspermia' literally refer to?

<p>Seeds everywhere. (B)</p> Signup and view all the answers

Which of the following was NOT a proposed idea on the origin of life according to the content?

<p>Life originated on Earth through gradual chemical reactions. (B)</p> Signup and view all the answers

What evidence supports the Panspermia theory related to meteorites?

<p>Discovery of left-handed amino acids, bacteria, and carbon, protected within rocks. (D)</p> Signup and view all the answers

According to the content, which celestial body might have been more conducive to life in its early stages than Earth?

<p>Mars (D)</p> Signup and view all the answers

Who provided the first blow to the spontaneous generation theory?

<p>Francesco Redi (D)</p> Signup and view all the answers

What did Needham and Buffon's experiments, involving heated mutton broth, suggest about the origin of microbes?

<p>Microbes could still grow after broth was heated, supporting spontaneous generation. (B)</p> Signup and view all the answers

According to the content, what is a main criticism of the colonization theory?

<p>It simply moves the question of the origin of life to another location. (A)</p> Signup and view all the answers

What is the primary characteristic that suggested the parallel evolution of proteins and nucleic acids?

<p>The ability of polynucleotides to replicate coupled with polypeptide catalysis. (D)</p> Signup and view all the answers

According to the text provided, what is the role of ribozymes in the evolution of life?

<p>They preceded translation systems. (C)</p> Signup and view all the answers

What is the essential function of a membrane in the context of early cell formation?

<p>It separates the cell's contents from its surroundings, preventing dilution. (B)</p> Signup and view all the answers

What distinguishes Oparin's protobionts from Fox’s thermal proteinoids?

<p>They were formed from artificially created polymers from living systems such as gum arabic. (B)</p> Signup and view all the answers

What is a major drawback of the membranes of Fox’s proteinoids according to the text?

<p>They were too permeable. (C)</p> Signup and view all the answers

What process did Oparin suggest for the formation of protobionts?

<p>Coacervation of highly hydrated polymers in an aqueous solution. (D)</p> Signup and view all the answers

Which of the following is NOT considered a fundamental characteristic of life?

<p>Inertia (D)</p> Signup and view all the answers

What evolutionary pressure likely led to the development of metabolic pathways?

<p>Competition for available nutrients. (B)</p> Signup and view all the answers

According to the provided text, what is the simplest structure within which life is invested?

<p>A cell with a well-defined boundary (B)</p> Signup and view all the answers

What is the primary significance of the reproductive machinery that developed in early life forms?

<p>To ensure progeny cells inherit all the metabolic capabilities of the parent cell. (A)</p> Signup and view all the answers

Why were the biologically important compounds spared from oxidative alteration in the prebiotic environment?

<p>The absence of oxygen in the atmosphere. (A)</p> Signup and view all the answers

Which statement best describes the progression of evolution as described in the text?

<p>RNA enzymes (ribozymes) predated translation systems before protein enzymes. (A)</p> Signup and view all the answers

What is the primary function of replication in the context of living organisms?

<p>To ensure continuity of life and prevent extinction (A)</p> Signup and view all the answers

What is a key focus of Complex Systems Biology (CSB)?

<p>The complex interactions within bionetworks and fundamental relational patterns in life. (C)</p> Signup and view all the answers

According to the Primordial Soup Theory, where did the chemical accumulation that would eventually lead to life primarily occur?

<p>In concentrated regions of the oceans or ponds. (D)</p> Signup and view all the answers

Which of the following best describes a 'living system' as defined in the text?

<p>An open self-organizing system that interacts with its environment (B)</p> Signup and view all the answers

According to the content, what is a primary reason life does not exist on all planets?

<p>Many planets do not have the necessary conditions to support life. (D)</p> Signup and view all the answers

What was the crucial role of energy sources in the formation of life according to the Primordial Soup Theory?

<p>To energize simple molecules to form basic building blocks of proteins. (B)</p> Signup and view all the answers

What role does mutation play in the evolution of life?

<p>It allows progeny to change under the pressure of natural selection (A)</p> Signup and view all the answers

Which of the following is NOT typically considered a necessary condition for life on Earth, according to the text?

<p>High levels of radiation (D)</p> Signup and view all the answers

The first organisms, as proposed by Oparin and Haldane, are thought to have been:

<p>Heterotrophs consuming other organisms for energy. (B)</p> Signup and view all the answers

What is the main concept of the Gaia hypothesis?

<p>Organisms and their inorganic surroundings form a self-regulating system. (C)</p> Signup and view all the answers

What describes the location of Kepler-62?

<p>A star in the constellation Lyra, 1,200 light years from Earth. (A)</p> Signup and view all the answers

In the Miller-Urey experiment, what was the significance of electrically sparking the mixture of gases?

<p>To provide energy similar to lightning in the primitive atmosphere. (C)</p> Signup and view all the answers

Which phrase best describes how living systems are maintained?

<p>By flows of information, energy and matter. (D)</p> Signup and view all the answers

What is a noted characteristic of Kepler-62 when compared to our Sun?

<p>Kepler-62 is cooler and smaller. (A)</p> Signup and view all the answers

Besides electricity, what other forms of energy have been shown to be capable of exciting gases and producing amino acids?

<p>Ultraviolet light, heat and shock (B)</p> Signup and view all the answers

What is a key feature that differentiates living from inanimate entities according to the text?

<p>The capacity for signaling and self-sustaining processes (C)</p> Signup and view all the answers

What is the basic chemical process behind the Strecker synthesis?

<p>Reaction of an aldehyde with HCN to form amino acids (A)</p> Signup and view all the answers

Which statement describes a viewpoint associated with 'special creation' regarding the origin of life?

<p>Life is so complex that it required a supernatural force to generate it. (D)</p> Signup and view all the answers

According to the content, what concern do some scientists have for the viewpoint of special creation?

<p>It is mystical and cannot be proved, and it does not obey natural laws. (D)</p> Signup and view all the answers

What best describes the main goal of Complex Systems Biology (CSB)

<p>To uncover and model relational patterns essential to life (A)</p> Signup and view all the answers

Flashcards

Life

Life is a process that can sustain itself, replicate, and change through mutations.

Cell

A basic unit of life with a defined boundary that contains all the necessary components for its own functions.

Evolution

The ability of life to change over time, leading to the emergence of new species.

Homeostasis

The ability of living systems to maintain a stable internal environment.

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Metabolism

The sum of all chemical reactions occurring within a living organism.

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Growth

The process of increasing in size and complexity.

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Responsiveness

The ability to respond to changes in the environment.

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Reproduction

The ability to produce offspring, ensuring the continuation of the species.

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Panspermia

The theory that life on Earth originated from life forms that arrived from outer space.

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Spontaneous Generation

The theory that life on Earth arose from non-living matter, such as soil or broth.

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Redi's Experiment

Francesco Redi's experiment disproved spontaneous generation by showing that maggots only appeared in meat that was exposed to flies.

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Spontaneous Generation - Early Beliefs

The early idea that life can arise spontaneously from non-living matter, even in controlled environments.

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Bacteria and Space Survival

Bacteria's ability to survive harsh conditions in space, providing support for Panspermia.

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Meteorite Evidence

Evidence suggesting that life could have originated from outer space, based on the presence of organic molecules and even microbial life in meteorites.

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Mars as a Possible Origin of Life

Mars being a potential source of life, suggesting that Panspermia could have occurred between Mars and Earth.

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Universal Common Ancestor

The theory that life originated from a single, common ancestor.

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Primordial Soup

A hypothetical early Earth environment where simple organic molecules formed from inorganic matter, providing the building blocks for life.

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Primordial Soup Theory

A theory proposing that life arose from non-living matter in a watery environment, through the combination of chemicals and energy sources.

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Formose Reaction

The process by which simple sugars are formed from formaldehyde in the presence of a catalyst.

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Strecker Synthesis

A chemical reaction that creates amino acids from aldehydes, ammonia, and hydrogen cyanide.

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Amino Acids

The fundamental molecules that combine to form proteins, which are essential for life.

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Miller-Urey Experiment

A famous experiment conducted by Stanley Miller and Harold Urey in 1950 that simulated the conditions of early Earth and produced amino acids, supporting the primordial soup theory.

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Heterotrophs

Organisms that obtain energy by consuming other organisms, unlike autotrophs which create their own food.

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Autotrophs

Organisms that produce their own food using energy from sunlight, like plants.

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What is complex systems biology?

The study of the complex structures and functions of living things, particularly focusing on interconnected networks and their essential patterns.

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How is complex systems biology different from traditional systems biology?

It's not only about simplified models, but also about discovering and modeling crucial relational patterns in life, which makes it distinct from other approaches.

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Why doesn't life occur on all planets?

Conditions like temperature, water, and atmosphere must be suitable for life to exist. Earth has the just-right combination for life to thrive.

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What is a habitable zone?

A region around a star where conditions might allow for liquid water on the surface of planets, potentially making them habitable.

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Tell me about Kepler-62.

A star that is cooler and smaller than our Sun, found in the Lyra constellation. Two of its planets, Kepler-62e and Kepler-62f, are within the star's habitable zone.

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What is the special creation view of life's origin?

The belief that life originated from a supernatural force, often a divine creator. It's a common belief in many religions.

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What is a criticism of the special creation view?

The issue with the special creation view is that it's not scientifically provable and relies on mystical explanations.

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What is the natural origin view of life's origin?

The belief that life arose naturally through a specific series of physical and chemical processes.

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Parallel evolution of proteins and nucleic acids

The idea that DNA and proteins evolved together, with DNA specifying protein sequences and proteins assisting in DNA replication.

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Ribozyme

A type of RNA that can act as an enzyme, suggesting that RNA may have played a more central role in early life than initially thought.

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Formation of cellular membranes

The process by which a cell's membrane forms, allowing for the separation and organization of life's components.

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Protobionts

Hypothetical early life forms proposed by Oparin, formed by the spontaneous separation of polymers in a solution.

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Coacervation

A process where a solution of polymers separates into phases with different polymer concentrations, possibly a step in the formation of protobionts.

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Fox's thermal proteinoids

Small, spherical structures formed by proteins under specific conditions, also proposed as possible early life forms.

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Development of metabolic pathways

The evolution of biochemical pathways due to competition for limited resources, leading to more efficient utilization of nutrients.

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Photosynthesis Evolution

The process by which life on Earth utilized sunlight as an inexhaustible energy source, initially using hydrogen sulfide (H2S) as a reducing agent, then switching to water (H2O) due to H2S depletion. This transition resulted in the production of oxygen (O2) as a byproduct.

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Oxygenic Metabolism

The evolution of metabolic pathways that exploited the newly abundant oxygen (O2) produced by photosynthesis. This provided a more efficient form of energy metabolism, leading to the rise of aerobic organisms.

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Ozone Layer Formation

The formation of the ozone layer in the Earth's atmosphere, a crucial protection against harmful ultraviolet (UV) radiation from the sun, which became possible due to increasing levels of oxygen (O2) produced by photosynthesis.

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Early Earth's UV Exposure

The early Earth lacked an ozone layer due to limited oxygen (O2) in the atmosphere, making it vulnerable to harmful UV radiation. This had a significant impact on early life forms.

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Photosynthesis Transition

The shift from using hydrogen sulfide (H2S) to water (H2O) as a reducing agent in photosynthesis, which resulted in the production of oxygen (O2) as a byproduct and paved the way for the oxygenation of the atmosphere.

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Study Notes

Biological Chemistry: Evolution of Living Organisms

  • Life is defined as a self-sustaining, replicating, and mutating process.
  • Self-sustenance allows for repair of damage or material loss.
  • Replication ensures the continuity of life.
  • Mutation allows progeny to adapt to changing environments.
  • Life is not possible on all planets due to varied environmental conditions.
  • Earth's conditions allow for life.

Various Views on the Origin of Life

  • Special Creation: Life's complexity required a supernatural force for genesis. This view is held by various religious traditions.
  • Some scientists criticize this view as mystical and unprovable, not adhering to natural laws.
  • Colonization Theory (Panspermia): Life originated elsewhere in the universe and was transported to Earth. It could have been in the form of living spores or directed by intelligent forces. This theory postulates an extra-terrestrial origin of life.

Evidence for Panspermia

  • Bacteria can withstand harsh space conditions (UV radiation, bombardment, etc.).
  • Meteorites contain organic molecules, such as amino acids.
  • Some scientists propose Mars as a potential source of life for Earth.

Spontaneous Generation Theory

  • Life spontaneously arose from non-living matter, as suggested by Aristotle, Van Helmont, and others.
  • Francesco Redi's experiments contradicted spontaneous generation concerning large organisms.
  • Needham and Buffon's experiments supported spontaneous generation for microbes but had experimental flaws and errors.
  • Louis Pasteur decisively disproved spontaneous generation for microbes.

Long-Term Spontaneous Generation

  • JBS Haldane and A.I. Oparin suggested life evolved from non-living matter.
  • Raw materials and energy sources (sunlight, lightning) were necessary for the synthesis of monomers and macromolecules for cells.

Prebiotic Soup Theory

  • Biologically crucial compounds were created without oxidation due to a lack of oxygen.
  • These prebiotic compounds could persist during precipitation and build up in oceans and ponds.
  • Life may have begun in bodies of water due to interactions between environmental chemicals and energy sources, creating amino acids and proteins that could evolve into life.
  • Russian scientist A.I. Oparin and English geneticist J.B.S. Haldane independently developed this theory.

Prebiotic Synthesis of Molecules

  • The formation of complex organic molecules from simple ones.
  • Prebiotic synthesis of monosaccharides (formose reaction): Formation of sugars from formaldehyde.
  • Prebiotic synthesis of amino acids (Strecker synthesis): Synthesis of amino acids from aldehydes and HCN.
  • Prebiotic synthesis of nucleotide bases: Formation of building blocks of DNA and RNA from HCN.
  • Prebiotic synthesis of fatty acids: Formation necessitates high temperatures and pressures.

Polymerization and Condensing Agents

  • Polymerization is the formation of complex molecules from monomers.
  • Water removal (dehydration) is necessary for polymerization.
  • Condensing agents (e.g., polyphosphates, cyanides, carbodiimides) could drive polymerization reactions in prebiotic conditions by removing water.

Polypeptides and Polynucleotides

  • Polymerization, while possible, faced a significant challenge from water competition.
  • Methods to lower water, like evaporation, could concentrate the reactants for polymerization.
  • Adsorption to charged mineral surfaces (clay, micas) aids the concentration process.
  • Template-directed synthesis, and non-template-directed synthesis, of these polymers were possible.

Formation of Cells and Membranes

  • Simple cellular structures (protobionts).
  • Membranes are crucial for compartmentalization to prevent dilution.
  • Oparin & Fox's investigations on protobiont formation via coacervation.

Development of Metabolic Pathways

  • Competition for resources drove the evolution of metabolic pathways.
  • Scarcity promoted development of enzymatic systems to produce necessary materials from simpler precursors.
  • Energy production pathways evolved from using existing energy-rich substances.

The Primitive Atmosphere

  • The primitive atmosphere lacked oxygen and ozone, allowing for prebiotic chemical reactions to occur.
  • The lack of oxygen also allowed for the preservation of organic molecules that would have otherwise been altered by the oxidation of oxygen.
  • The matter forming the Earth was largely reductive, like hydrogen.

Summary of Evolution

  • Exogenous Delivery: Evidence suggests that materials like water and organic molecules may have arrived on Earth from space through comets, asteroids, etc.
  • Endogenous Synthesis: These materials also were able to produce by Earth's processes to support life.

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