BIOL 4130H Human Cell Biology Quiz

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Questions and Answers

What is the weight of the final exam in the course evaluation?

30% (correct)
15%
50%
20%

Journal Article Quizzes can be made up if a student misses the scheduled date.

False (B)

What is the email address of Dr. Robert Huber?

[email protected]

The course textbook is titled _____ World of the Cell.

Becker's Signup and view all the answers

Match the following evaluations with their corresponding percentages:

Journal Article Critique = 15% Research Proposal = 20% Midterm = 20% Final Exam = 30% Signup and view all the answers

When is the midterm exam scheduled?

October 28 (B) Signup and view all the answers

Office hours for Dr. Robert Huber are specified in the course details.

False (B) Signup and view all the answers

Lectures for BIOL 4130H are held on _____ at 7:00 PM.

Mondays Signup and view all the answers

What allows HeLa cells to not age or die?

Abnormal telomerase expression (B) Signup and view all the answers

HeLa cells shorten their telomeres and thus age like normal cells.

False (B) Signup and view all the answers

What did the estate of Henrietta Lacks seek from ThermoFisher?

Financial disclosure about how much money was made from the commercialization of her cells. Signup and view all the answers

HeLa cells do not undergo normal aging due to their expression of _____, which prevents telomere shortening.

telomerase Signup and view all the answers

Match the following aspects regarding Henrietta Lacks with their descriptions:

ThermoFisher = Company involved in the lawsuit HeLa cells = Cells that do not age or die Estate of Henrietta Lacks = Requested financial disclosure Settlement = Agreement reached with ThermoFisher Signup and view all the answers

What happens if a student misses the midterm?

Their grade will go to the final exam (A) Signup and view all the answers

A late penalty of 10% is imposed for every day an assignment is late.

False (B) Signup and view all the answers

Name the three strands of biological inquiry that contribute to modern cell biology.

Cytology, Biochemistry, Genetics Signup and view all the answers

Students should ensure to take detailed ______ during lectures.

notes Signup and view all the answers

Match the scientific focus to its definition:

Cytology = Focuses on cellular structure using optical techniques Biochemistry = Studies cellular structure, function, and metabolism Genetics = Examines information flow and heredity Cellular approaches = Utilizes light microscopy and other techniques Signup and view all the answers

Which of the following is a learning objective of the course?

To critically analyze primary literature (C) Signup and view all the answers

Students are encouraged to wait until the last minute to ask for help.

False (B) Signup and view all the answers

Recent technological advances have improved knowledge about the ______.

human cell Signup and view all the answers

Which treatment strategy prevents the formation of amyloid plaques in Alzheimer’s disease?

RNAi to inhibit translation of plaque-associated proteins (D) Signup and view all the answers

Light microscopy is generally used for observing living cells.

False (B) Signup and view all the answers

What is the primary advantage of phase contrast microscopy?

It allows the examination of living cells by providing different levels of brightness. Signup and view all the answers

Differential interference contrast microscopy is preferred for examining __________ cells.

living Signup and view all the answers

Match the microscopy technique with its description:

Phase contrast microscopy = Examines behavior of living cells Fluorescence microscopy = Uses fluorescent dyes to visualize structures Confocal microscopy = Provides 3D images with improved resolution Light microscopy = Used for fixed tissues highlighting cell shape Signup and view all the answers

What is one potential side effect of using Aβ polypeptides in treatments?

They are necessary for neuronal function (C) Signup and view all the answers

Fluorescence microscopy can only be used on fixed tissues.

False (B) Signup and view all the answers

What is the result of phase-shifting in phase contrast microscopy?

Different parts of the cell appear as different levels of brightness. Signup and view all the answers

What is the primary function of nucleic acids?

Store, transmit, and express genetic information (C) Signup and view all the answers

All lipids are formed through linear polymerization.

False (B) Signup and view all the answers

What type of proteins act as catalysts in chemical reactions?

Enzymes Signup and view all the answers

Aβ polypeptides are not soluble in the _______ environment.

extracellular Signup and view all the answers

Match the following classes of proteins with their functions:

Enzymes = Increase reaction rates Motility proteins = Facilitate movement Structural proteins = Provide physical support Transport proteins = Move substances across membranes Signup and view all the answers

Which type of proteins is involved in cell communication?

Signaling proteins (D) Signup and view all the answers

Most forms of Alzheimer's Disease are hereditary.

False (B) Signup and view all the answers

What protein is hyperphosphorylated in neurofibrillary tangles in Alzheimer's Disease?

Tau Signup and view all the answers

Tau functions to stabilize _______.

microtubules Signup and view all the answers

What role does apolipoprotein E (APOE) have in Alzheimer's Disease?

It is involved in cholesterol transport (C) Signup and view all the answers

What type of antibodies are produced when an animal's immune system responds to an antigen?

Polyclonal antibodies (C) Signup and view all the answers

Monoclonal antibodies are non-renewable.

False (B) Signup and view all the answers

What are the two regions of an antibody that are identical to each other but unique for each antibody called?

Variable regions Signup and view all the answers

Antibodies produced from cultured hybrid cells are called __________.

monoclonal antibodies Signup and view all the answers

Match the type of antibody with its characteristic:

Polyclonal antibodies = Non-renewable and recognize different sites Monoclonal antibodies = Renewable and single specificity Hybridomas = Cells resulting from fusion of B lymphocytes and myeloma cells Antigen-binding site = Region that attaches to a specific antigen Signup and view all the answers

What is one major drawback of polyclonal antibodies?

They are non-renewable (A) Signup and view all the answers

Phagocytic cells function to destroy antigens by digesting them.

True (A) Signup and view all the answers

What is the role of plasma B cells in the immune response?

They produce antibodies that bind to and inactivate antigens. Signup and view all the answers

The constant region of an antibody is __________ for all antibodies of a particular type.

the same Signup and view all the answers

Which animal is NOT commonly used for antibody production?

Goldfish (B) Signup and view all the answers

Flashcards

No make-up test

There is no opportunity to retake a missed midterm exam.

Midterm grade redistribution

If you miss the midterm, your grade will be added to the final exam score.