Podcast
Questions and Answers
What is the main advantage of using BLOSUM for comparing sequences?
What is the main advantage of using BLOSUM for comparing sequences?
- It is better suited for comparing distantly related sequences (correct)
- It is faster than other algorithms
- It is more sensitive to sequence divergence
- It has a higher accuracy rate
Which type of BLAST algorithm is specifically designed for searching short similar sequences?
Which type of BLAST algorithm is specifically designed for searching short similar sequences?
- blastx
- tblastn
- blastn (correct)
- megablast
What feature of a gene does an exon represent?
What feature of a gene does an exon represent?
- The part that is protein coding (correct)
- The overall length of the gene
- The untranslated regulatory region at the gene ends
- The initial seed for cross-species comparisons
What does a heuristic algorithm do in the context of solving a problem?
What does a heuristic algorithm do in the context of solving a problem?
Which BLAST program is best suited for closely related sequences with a target percent identity of 95% or more?
Which BLAST program is best suited for closely related sequences with a target percent identity of 95% or more?
What is the main difference between blastn and tblastx algorithms?
What is the main difference between blastn and tblastx algorithms?
What does the term Megablast refer to in the context of the provided text?
What does the term Megablast refer to in the context of the provided text?
What is the main difference between BLOSUM and PAM matrices?
What is the main difference between BLOSUM and PAM matrices?
What is the significance of having a lower N50 value when analyzing sequences?
What is the significance of having a lower N50 value when analyzing sequences?
What is a Contig in the context of genetic sequencing?
What is a Contig in the context of genetic sequencing?
In what way does the Blossom algorithm differ from the Pam matrix?
In what way does the Blossom algorithm differ from the Pam matrix?
When choosing between Blastn, Blastp, and Blastx programs, which would be most suitable for short dissimilar sequences?
When choosing between Blastn, Blastp, and Blastx programs, which would be most suitable for short dissimilar sequences?