Podcast
Questions and Answers
What breakthrough method did Frederick Sanger develop for sequencing DNA?
What breakthrough method did Frederick Sanger develop for sequencing DNA?
- Utilizing dideoxy chain termination with a molecular inhibitor (correct)
- Applying fluorescent dye labeling for fragment visualization
- Employing restriction enzymes to cut DNA at specific sequences
- Using polymerase chain reaction to amplify DNA fragments
In what year did Frederick Sanger win the Nobel Prize in Chemistry for his research on insulin?
In what year did Frederick Sanger win the Nobel Prize in Chemistry for his research on insulin?
- 1960
- 1958 (correct)
- 1955
- 1967
What motivated Sanger to move to the laboratory of Molecular Biology in Cambridge, UK?
What motivated Sanger to move to the laboratory of Molecular Biology in Cambridge, UK?
- A passion for understanding the genetic material sequence (correct)
- To collaborate with other Nobel laureates
- The desire to develop synthetic proteins
- To establish a new protein synthesis technique
Which organism's RNA did Sanger successfully sequence by 1967?
Which organism's RNA did Sanger successfully sequence by 1967?
What challenge did Sanger face when shifting his focus to DNA sequencing in the early 1970s?
What challenge did Sanger face when shifting his focus to DNA sequencing in the early 1970s?
What was the primary focus of John Sulston's research?
What was the primary focus of John Sulston's research?
Which significant contribution did John Sulston make to the Human Genome Project?
Which significant contribution did John Sulston make to the Human Genome Project?
What was Sanger's method instrumental in achieving?
What was Sanger's method instrumental in achieving?
Which of the following statements about the C. elegans genome sequencing is accurate?
Which of the following statements about the C. elegans genome sequencing is accurate?
In what year did John Sulston share the Nobel Prize?
In what year did John Sulston share the Nobel Prize?
What was the primary focus of Frederick Sanger's doctoral research?
What was the primary focus of Frederick Sanger's doctoral research?
In which year did Frederick Sanger develop the dideoxy method of DNA sequencing?
In which year did Frederick Sanger develop the dideoxy method of DNA sequencing?
Which aspect of his career did Frederick Sanger identify as his greatest strength?
Which aspect of his career did Frederick Sanger identify as his greatest strength?
What impact did Sanger's work have on the field of molecular biology?
What impact did Sanger's work have on the field of molecular biology?
What was one contribution of the Wellcome Sanger Institute established in 1993?
What was one contribution of the Wellcome Sanger Institute established in 1993?
Which of the following statements about Sanger's early life is true?
Which of the following statements about Sanger's early life is true?
What distinguishes Sanger Sequencing from other DNA sequencing techniques?
What distinguishes Sanger Sequencing from other DNA sequencing techniques?
Which prize did Frederick Sanger share in 1980 for his contributions to science?
Which prize did Frederick Sanger share in 1980 for his contributions to science?
Flashcards
Frederick Sanger
Frederick Sanger
A two-time Nobel laureate and biochemist known for sequencing DNA and proteins.
Sanger Sequencing
Sanger Sequencing
A method of DNA sequencing developed by Frederick Sanger using the dideoxy technique.
Nobel Prize in Chemistry 1958
Nobel Prize in Chemistry 1958
Awarded to Sanger for his work on the sequencing of insulin, marking a significant achievement in biochemistry.
Amino Acids
Amino Acids
The building blocks of proteins that Sanger studied for his PhD.
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Wellcome Sanger Institute
Wellcome Sanger Institute
A genome research center established by Sanger in 1993, significant in genomic studies.
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Dideoxy Method
Dideoxy Method
A technique developed by Sanger for DNA sequencing which involves chain termination.
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Insulin Structure
Insulin Structure
The unique amino acid arrangement and 3D shape of insulin, completed by Sanger's team in 1955.
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Protein Synthesis
Protein Synthesis
The process where amino acids are arranged into proteins, central to Sanger's research.
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John Sulston
John Sulston
An English biologist known for his work on C. elegans and cell death.
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C. elegans
C. elegans
A nematode worm used for studying cell differentiation and death.
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Nobel Prize 2002
Nobel Prize 2002
Award shared by Sulston for his research on programmed cell death.
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Human Genome Project
Human Genome Project
A project from 1990-2003 to map the entire human genome.
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Sanger's Sequencing Method
Sanger's Sequencing Method
A method for isolating and sequencing DNA fragments.
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Synthetic insulin
Synthetic insulin
Insulin created through synthetic methods for diabetes treatment, developed after Sanger's protein research.
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DNA sequencing
DNA sequencing
A method for determining the precise order of nucleotides in a DNA molecule.
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Dideoxy chain termination
Dideoxy chain termination
A technique used by Sanger to sequence DNA, stopping replication at specific points.
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RNA sequencing
RNA sequencing
The process of determining the sequence of RNA, achieved by Sanger in 1967 using E. coli.
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